DK0780125T3 - Anvendelse af hydantoinderivater til fremstilling af et lægemiddel til behandling af sygdomme associeret med tilstedeværelse af aktivt oxygen og frie radikaler - Google Patents

Anvendelse af hydantoinderivater til fremstilling af et lægemiddel til behandling af sygdomme associeret med tilstedeværelse af aktivt oxygen og frie radikaler

Info

Publication number: DK0780125T3
Authority: DK; Denmark
Prior art keywords: diseases; free radicals; active oxygen; group; medicament
Prior art date: 1995-12-20

Application number

DK96120597T

Other languages

English (en)

Inventor

Hitoshi Endou

Kazuharu Ienaga

Original Assignee

Nippon Zoki Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-12-20

Filing date

1996-12-20

Publication date

2001-05-07

1996-12-20 Application filed by Nippon Zoki Pharmaceutical Co filed Critical Nippon Zoki Pharmaceutical Co

2001-05-07 Application granted granted Critical

2001-05-07 Publication of DK0780125T3 publication Critical patent/DK0780125T3/da

Links

201000010099 disease Diseases 0.000 title abstract 4
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 4
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 title abstract 3
150000001469 hydantoins Chemical class 0.000 title abstract 3
239000001301 oxygen Substances 0.000 title abstract 3
229910052760 oxygen Inorganic materials 0.000 title abstract 3
229940053195 antiepileptics hydantoin derivative Drugs 0.000 title 1
239000003814 drug Substances 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
208000036487 Arthropathies Diseases 0.000 abstract 1
208000023275 Autoimmune disease Diseases 0.000 abstract 1
208000002177 Cataract Diseases 0.000 abstract 1
206010016654 Fibrosis Diseases 0.000 abstract 1
208000012659 Joint disease Diseases 0.000 abstract 1
208000019693 Lung disease Diseases 0.000 abstract 1
206010040070 Septic Shock Diseases 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
239000003937 drug carrier Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000004761 fibrosis Effects 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
208000010125 myocardial infarction Diseases 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
239000008177 pharmaceutical agent Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000005855 radiation Effects 0.000 abstract 1
230000010410 reperfusion Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000036303 septic shock Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

DK96120597T 1995-12-20 1996-12-20 Anvendelse af hydantoinderivater til fremstilling af et lægemiddel til behandling af sygdomme associeret med tilstedeværelse af aktivt oxygen og frie radikaler DK0780125T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP34983195		1995-12-20

Publications (1)

Publication Number	Publication Date
DK0780125T3 true DK0780125T3 (da)	2001-05-07

Family

ID=18406411

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK96120597T DK0780125T3 (da)	1995-12-20	1996-12-20	Anvendelse af hydantoinderivater til fremstilling af et lægemiddel til behandling af sygdomme associeret med tilstedeværelse af aktivt oxygen og frie radikaler

Country Status (11)

Country	Link
US (1)	US6197806B1 (da)
EP (1)	EP0780125B1 (da)
KR (1)	KR100468109B1 (da)
CN (1)	CN1093401C (da)
AT (1)	ATE200622T1 (da)
AU (1)	AU705447B2 (da)
CA (1)	CA2193551C (da)
DE (1)	DE69612540T2 (da)
DK (1)	DK0780125T3 (da)
ES (1)	ES2158223T3 (da)
TW (1)	TW461814B (da)

Families Citing this family (13)

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AU775606B2 (en) *	1998-08-31	2004-08-05	Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The	Methimazole derivatives and tautomeric cyclic thiones to treat autoimmune diseases
AU754989B2 (en) *	1998-11-16	2002-11-28	Nippon Zoki Pharmaceutical Co., Ltd.	A therapeutic agent for intractable vasculitis
JP4711523B2 (ja)	2001-02-13	2011-06-29	日本臓器製薬株式会社	低アルブミン血症改善剤
US6919365B2 (en)	2001-04-11	2005-07-19	Senju Pharmaceutical Co., Ltd.	Imidazolidinedione derivatives and use thereof as drugs
BRPI0214256B8 (pt) *	2001-11-19	2021-05-25	Medigene Ag	medicamento
TWI353979B (en) *	2002-04-10	2011-12-11	Nippon Zoki Pharmaceutical Co	Novel crystal form of 5-hydroxy-1-methylhydantoin
US20060241162A1 (en) *	2005-04-20	2006-10-26	Kaoru Okamoto	Optically active (R)-hydantoin derivative
US20060241163A1 (en) *	2005-04-20	2006-10-26	Kaoru Okamoto	Optically active (S)-hydantoin derivative
CN101732348B (zh)	2008-11-11	2015-01-14	威世药业（如皋）有限公司	牛痘疫苗致炎兔皮提取物在制备急性脑血管疾病治疗药物中的用途
BRPI1107312B1 (pt) *	2011-11-25	2021-09-08	Universidade Federal De Santa Catarina	Composto de acil-hidrazona
EP2801573A1 (en) *	2013-05-09	2014-11-12	Sanofi	Hydantoine derivatives as CD38 inhibitors
CN103360320B (zh) *	2013-07-30	2015-12-02	邱智东	1-甲基海因的制备方法
EP3639821B1 (en)	2017-06-13	2024-08-28	National Cancer Center	Carcinogenesis inhibitor

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JP2567593B2 (ja)	1986-12-29	1996-12-25	日本臓器製薬株式会社	イミダゾリジントリオン誘導体及び該化合物を有効成分として含有するアレルギ−性疾患治療剤
JPS6456614A (en)	1987-08-27	1989-03-03	Ono Pharmaceutical Co	Maillard reaction inhibitor
JPH01156965A (ja)	1987-09-29	1989-06-20	Taiho Yakuhin Kogyo Kk	チオヒダントイン化合物
JP2544183B2 (ja)	1988-07-29	1996-10-16	日本臓器製薬株式会社	新規パラバン酸誘導体及び該化合物を有効成分として含有する医薬組成物
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JPH02225485A (ja)	1989-02-27	1990-09-07	Taiho Yakuhin Kogyo Kk	チエノピリミジン―３―酢酸誘導体
CA2011899A1 (en)	1989-03-13	1990-09-13	Masaaki Toda	Benzopyran derivatives
JP2678499B2 (ja)	1989-08-09	1997-11-17	日本臓器製薬株式会社	尿毒症毒素低下剤
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1996
- 1996-12-18 US US08/769,008 patent/US6197806B1/en not_active Expired - Fee Related
- 1996-12-19 CN CN96123286A patent/CN1093401C/zh not_active Expired - Fee Related
- 1996-12-20 DE DE69612540T patent/DE69612540T2/de not_active Expired - Lifetime
- 1996-12-20 ES ES96120597T patent/ES2158223T3/es not_active Expired - Lifetime
- 1996-12-20 EP EP96120597A patent/EP0780125B1/en not_active Expired - Lifetime
- 1996-12-20 KR KR1019960069207A patent/KR100468109B1/ko not_active Expired - Lifetime
- 1996-12-20 AT AT96120597T patent/ATE200622T1/de not_active IP Right Cessation
- 1996-12-20 AU AU76414/96A patent/AU705447B2/en not_active Ceased
- 1996-12-20 CA CA002193551A patent/CA2193551C/en not_active Expired - Fee Related
- 1996-12-20 DK DK96120597T patent/DK0780125T3/da active
1997
- 1997-01-04 TW TW086100051A patent/TW461814B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
TW461814B (en)	2001-11-01
ATE200622T1 (de)	2001-05-15
EP0780125A2 (en)	1997-06-25
CA2193551A1 (en)	1997-06-21
EP0780125A3 (en)	1997-11-05
ES2158223T3 (es)	2001-09-01
DE69612540T2 (de)	2001-08-30
DE69612540D1 (de)	2001-05-23
KR100468109B1 (ko)	2005-04-13
AU7641496A (en)	1997-06-26
CN1093401C (zh)	2002-10-30
CN1159324A (zh)	1997-09-17
CA2193551C (en)	2006-03-21
KR970032863A (ko)	1997-07-22
EP0780125B1 (en)	2001-04-18
AU705447B2 (en)	1999-05-20
US6197806B1 (en)	2001-03-06

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