ATE261307T1 - Verwendung von misoprostol und/oder misoprostolsäure zur behandlung von erektionsstörungen - Google Patents
Verwendung von misoprostol und/oder misoprostolsäure zur behandlung von erektionsstörungenInfo
- Publication number
- ATE261307T1 ATE261307T1 AT98913967T AT98913967T ATE261307T1 AT E261307 T1 ATE261307 T1 AT E261307T1 AT 98913967 T AT98913967 T AT 98913967T AT 98913967 T AT98913967 T AT 98913967T AT E261307 T1 ATE261307 T1 AT E261307T1
- Authority
- AT
- Austria
- Prior art keywords
- misoprostol
- erective
- disorder
- treat
- misoprostolic
- Prior art date
Links
- CNWGPXZGIIOYDL-MKYGPDKMSA-N 7-[(1r,2r,3r)-3-hydroxy-2-[(e)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoic acid Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O CNWGPXZGIIOYDL-MKYGPDKMSA-N 0.000 title abstract 2
- OJLOPKGSLYJEMD-URPKTTJQSA-N methyl 7-[(1r,2r,3r)-3-hydroxy-2-[(1e)-4-hydroxy-4-methyloct-1-en-1-yl]-5-oxocyclopentyl]heptanoate Chemical compound CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC OJLOPKGSLYJEMD-URPKTTJQSA-N 0.000 title abstract 2
- 229960005249 misoprostol Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000003966 vascular damage Effects 0.000 abstract 2
- 208000010228 Erectile Dysfunction Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 201000001881 impotence Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000003899 penis Anatomy 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gynecology & Obstetrics (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GR97100172 | 1997-05-06 | ||
| PCT/GR1998/000012 WO1998050039A1 (en) | 1997-05-06 | 1998-04-22 | Use of misoprostol or/and misoprostol acid for preparing drug in order to cure erectile dysfunction |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE261307T1 true ATE261307T1 (de) | 2004-03-15 |
Family
ID=10942965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98913967T ATE261307T1 (de) | 1997-05-06 | 1998-04-22 | Verwendung von misoprostol und/oder misoprostolsäure zur behandlung von erektionsstörungen |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US6210343B1 (de) |
| EP (1) | EP0980245B1 (de) |
| JP (1) | JP2001525803A (de) |
| AT (1) | ATE261307T1 (de) |
| AU (1) | AU6848098A (de) |
| DE (2) | DE69822295T2 (de) |
| ES (1) | ES2216279T3 (de) |
| GR (1) | GR1002847B (de) |
| PT (1) | PT980245E (de) |
| WO (1) | WO1998050039A1 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR1002847B (el) | 1997-05-06 | 1998-01-27 | Χρηση της μισοπροστολης ή/και της μισοπροστολης οξυ για την παρασκευη φαρμακευτικου προιοντος για τη θεραπευτικη αντιμετωπιση των δυσλειτουργιων της στυσεως | |
| US7087240B1 (en) * | 1998-06-25 | 2006-08-08 | Lavipharm Laboratories Inc. | Device and method for the treatment of erectile dysfunction |
| GR1003199B (el) | 1998-08-14 | 1999-09-01 | Χρηση της μισοπροστολης ή και της μισοπροστολης οξυ για την παρασκευη φαρμακευτικου προιοντος για τη θεραπευτικη αντιμετωπιση της σεξουαλικης δυσλειτουργιας στις γυναικες | |
| US6825234B2 (en) | 1998-12-10 | 2004-11-30 | Nexmed (Holdings) , Inc. | Compositions and methods for amelioration of human female sexual dysfunction |
| WO2000051978A1 (en) | 1999-03-01 | 2000-09-08 | Nitromed, Inc. | Nitrosated and nitrosylated prostaglandins, compositions and metods of use |
| US7479120B2 (en) * | 2002-02-22 | 2009-01-20 | Hans Gregersen | Method and apparatus for investigating force-deformation properties in muscles in walls of bodily hollow systems |
| US8287474B1 (en) | 2002-08-22 | 2012-10-16 | Koenig J Frank | Method and apparatus for noninvasively increasing whole body blood flow and noninvasive physical exercise of limbs from the outside and from within the limb to treat diseases throughout the body |
| US7037257B1 (en) * | 2002-08-22 | 2006-05-02 | Koenig J Frank | Erectile dysfuction treatments comprising momentary vacuum therapy alone or with medications |
| GB0222522D0 (en) | 2002-09-27 | 2002-11-06 | Controlled Therapeutics Sct | Water-swellable polymers |
| US20050255161A1 (en) * | 2004-05-10 | 2005-11-17 | Servet Buyuktimkin | Method for the long term stabilization of labile compounds at room temperature in pharmaceutical preparations containing water |
| GB0417401D0 (en) * | 2004-08-05 | 2004-09-08 | Controlled Therapeutics Sct | Stabilised prostaglandin composition |
| US20060286172A1 (en) * | 2005-06-03 | 2006-12-21 | Anu Mahashabde | Pharmaceutical compositions comprising prostanoid-receptor agonists and methods of making and using the same |
| GB0613333D0 (en) | 2006-07-05 | 2006-08-16 | Controlled Therapeutics Sct | Hydrophilic polyurethane compositions |
| GB0613638D0 (en) | 2006-07-08 | 2006-08-16 | Controlled Therapeutics Sct | Polyurethane elastomers |
| GB0620685D0 (en) | 2006-10-18 | 2006-11-29 | Controlled Therapeutics Sct | Bioresorbable polymers |
| JP2010095454A (ja) * | 2008-10-14 | 2010-04-30 | Cyclochem:Kk | 抗菌組成物 |
| WO2010070617A1 (en) * | 2008-12-19 | 2010-06-24 | Shimoda Biotech (Pty) Ltd | Inclusion complexes of alpha-cyclodextrin and sildenafil salt |
| RU2428933C1 (ru) * | 2010-02-19 | 2011-09-20 | Государственное образовательное учреждение высшего профессионального образования "Рязанский государственный медицинский университет имени акад. И.П. Павлова Федерального агентства по здравоохранению и социальному развитию" | Способ определения индекса функциональной достаточности артериального кровенаполнения кавернозной ткани по результатам ультрасонографии полового члена |
| RU2444989C1 (ru) * | 2010-09-27 | 2012-03-20 | Государственное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения и социального развития Российской Федерации (ГОУ ВПО Первый МГМУ им. И.М. Сеченова Минздравсоцразвития России) | Способ диагностики васкулогенной эректильной дисфункции |
| WO2017168174A1 (en) | 2016-04-02 | 2017-10-05 | N4 Pharma Uk Limited | New pharmaceutical forms of sildenafil |
| IT201600119871A1 (it) * | 2016-11-25 | 2018-05-25 | Sabatino Russo | Uso dell’associazione di inibitori della fosfodiesterasi 5 con prostaglandina e1 per il trattamento della disfunzione erettile |
| US11977085B1 (en) | 2023-09-05 | 2024-05-07 | Elan Ehrlich | Date rape drug detection device and method of using same |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4696821A (en) | 1983-10-11 | 1987-09-29 | Warner-Lambert Company | Transdermal delivery system for administration of nitroglycerin |
| US5256652A (en) | 1987-11-12 | 1993-10-26 | Pharmedic Co. | Topical compositions and methods for treatment of male impotence |
| ZA912984B (en) | 1990-04-25 | 1992-01-29 | Alza Corp | Treatment of erectile dysfunction |
| US5242391A (en) * | 1990-04-25 | 1993-09-07 | Alza Corporation | Urethral insert for treatment of erectile dysfunction |
| US5962528A (en) | 1991-07-03 | 1999-10-05 | Scott; Nathan Earl | Prostaglandin E2 /F2α combination for treating impotence |
| AU2300092A (en) * | 1991-07-03 | 1993-02-11 | Nathan E. Scott | Prostaglandin e2 treatment of impotence |
| US5252602A (en) * | 1991-10-11 | 1993-10-12 | Rafeul Alam | Effects of misoprostol on allergic responses |
| BR9203277A (pt) * | 1992-08-21 | 1994-03-01 | Cesar Roberto Dias Nahoum | Utilizaccao de drogas eretogenicas e respectivas metodologias de aplicacao |
| US5773457A (en) * | 1995-02-15 | 1998-06-30 | Cesar Roberto Dias Nahoum | Compositions |
| US5324746A (en) | 1993-02-12 | 1994-06-28 | Mckee Rex N | Method of treating damaged mucosal and epithelial tissues with misoprostol |
| US6007836A (en) | 1993-05-28 | 1999-12-28 | Vericade, Inc. | Transdermal vasodilator |
| FR2710649A1 (fr) | 1993-09-30 | 1995-04-07 | Germinal Sarl | Film polymérique à base de prolamines, son procédé de préparation et ses applications . |
| JP3901213B2 (ja) | 1994-08-05 | 2007-04-04 | インファルマ・ソシエテ・アノニム | ホスファチジルコリンとプロスタグランジンe1及び/又はトロキサールチンとの複合体を含有する、勃起不能の局所治療のための製剤 |
| US5612359A (en) | 1994-08-26 | 1997-03-18 | Bristol-Myers Squibb Company | Substituted biphenyl isoxazole sulfonamides |
| CN1126587A (zh) | 1995-01-10 | 1996-07-17 | 王怀秀 | 经阴囊睾酮缓释系统 |
| CA2215307A1 (en) | 1995-03-14 | 1996-09-19 | Vivus, Incorporated | Pharmaceutical compositions and kits for preventing erectile dysfunction |
| US5731339A (en) | 1995-04-28 | 1998-03-24 | Zonagen, Inc. | Methods and formulations for modulating the human sexual response |
| AUPN814496A0 (en) | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
| US5688499A (en) | 1996-03-13 | 1997-11-18 | Queen's University At Kingston | Antagonism of endothelin actions |
| US5684177A (en) | 1996-05-17 | 1997-11-04 | Torcan Chemical Ltd. | Misoprostol |
| GR1002847B (el) | 1997-05-06 | 1998-01-27 | Χρηση της μισοπροστολης ή/και της μισοπροστολης οξυ για την παρασκευη φαρμακευτικου προιοντος για τη θεραπευτικη αντιμετωπιση των δυσλειτουργιων της στυσεως | |
| US5976566A (en) | 1997-08-29 | 1999-11-02 | Macrochem Corporation | Non-steroidal antiinflammtory drug formulations for topical application to the skin |
| CA2306837C (en) | 1997-10-28 | 2007-05-08 | Vivus, Inc. | Treatment of female sexual dysfunction |
| US6046244A (en) | 1997-11-05 | 2000-04-04 | Nexmed Holdings, Inc. | Topical compositions for prostaglandin E1 delivery |
| US6277884B1 (en) | 1998-06-01 | 2001-08-21 | Nitromed, Inc. | Treatment of sexual dysfunction with N-hydroxyguanidine compounds |
| US5942545A (en) | 1998-06-15 | 1999-08-24 | Macrochem Corporation | Composition and method for treating penile erectile dysfunction |
| WO2000032195A1 (fr) | 1998-12-02 | 2000-06-08 | Mochida Pharmaceutical Co., Ltd. | Preparations destinees a etre administrees par voie uretrale |
| IL139941A0 (en) | 1999-12-02 | 2002-02-10 | Pfizer Prod Inc | Use of prostaglandin agonists to treat erectile dysfunction or impotence |
| US6323241B1 (en) | 2000-01-10 | 2001-11-27 | Nexmed (Holdings) Inc. | Prostaglandin compositions and methods of treatment for male erectile dysfunction |
| US6476037B1 (en) | 2000-03-23 | 2002-11-05 | The Regents Of The University Of California | L-arginine and phosphodiesterase (PDE) inhibitor synergism |
| WO2001070708A1 (en) | 2000-03-23 | 2001-09-27 | Merck & Co., Inc. | Substituted piperidines as melanocortin receptor agonists |
| JP2003527444A (ja) | 2000-03-23 | 2003-09-16 | メルク エンド カムパニー インコーポレーテッド | メラノコルチン受容体アゴニストとして作用するスピロピペリジン誘導体 |
| KR20030019628A (ko) | 2000-07-31 | 2003-03-06 | 오노 야꾸힝 고교 가부시키가이샤 | 프로스타글란딘 유도체를 유효 성분으로 하는 발기부전치료제 |
-
1997
- 1997-05-06 GR GR970100172A patent/GR1002847B/el not_active IP Right Cessation
-
1998
- 1998-04-22 AT AT98913967T patent/ATE261307T1/de not_active IP Right Cessation
- 1998-04-22 DE DE69822295T patent/DE69822295T2/de not_active Expired - Fee Related
- 1998-04-22 PT PT98913967T patent/PT980245E/pt unknown
- 1998-04-22 AU AU68480/98A patent/AU6848098A/en not_active Abandoned
- 1998-04-22 EP EP98913967A patent/EP0980245B1/de not_active Expired - Lifetime
- 1998-04-22 ES ES98913967T patent/ES2216279T3/es not_active Expired - Lifetime
- 1998-04-22 US US09/423,130 patent/US6210343B1/en not_active Expired - Fee Related
- 1998-04-22 WO PCT/GR1998/000012 patent/WO1998050039A1/en not_active Ceased
- 1998-04-22 JP JP54785598A patent/JP2001525803A/ja active Pending
- 1998-04-22 DE DE0980245T patent/DE980245T1/de active Pending
-
2000
- 2000-02-02 US US09/496,710 patent/US6589990B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6589990B1 (en) | 2003-07-08 |
| WO1998050039A1 (en) | 1998-11-12 |
| US6210343B1 (en) | 2001-04-03 |
| DE69822295T2 (de) | 2005-02-24 |
| DE980245T1 (de) | 2000-08-31 |
| AU6848098A (en) | 1998-11-27 |
| GR1002847B (el) | 1998-01-27 |
| JP2001525803A (ja) | 2001-12-11 |
| PT980245E (pt) | 2004-06-30 |
| EP0980245A1 (de) | 2000-02-23 |
| ES2216279T3 (es) | 2004-10-16 |
| EP0980245B1 (de) | 2004-03-10 |
| DE69822295D1 (de) | 2004-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0980245 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |