ATE261990T1 - Entzündungshemmende peptide des c-reaktiven proteins - Google Patents
Entzündungshemmende peptide des c-reaktiven proteinsInfo
- Publication number
- ATE261990T1 ATE261990T1 AT98929610T AT98929610T ATE261990T1 AT E261990 T1 ATE261990 T1 AT E261990T1 AT 98929610 T AT98929610 T AT 98929610T AT 98929610 T AT98929610 T AT 98929610T AT E261990 T1 ATE261990 T1 AT E261990T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- ile
- reactive protein
- human
- terminal
- Prior art date
Links
- 108010074051 C-Reactive Protein Proteins 0.000 title abstract 2
- 102100032752 C-reactive protein Human genes 0.000 title abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 101000933179 Homo sapiens Cathepsin G Proteins 0.000 abstract 2
- 101000851058 Homo sapiens Neutrophil elastase Proteins 0.000 abstract 2
- 102100033174 Neutrophil elastase Human genes 0.000 abstract 2
- 102000052896 human CTSG Human genes 0.000 abstract 2
- 206010001052 Acute respiratory distress syndrome Diseases 0.000 abstract 1
- 201000003883 Cystic fibrosis Diseases 0.000 abstract 1
- 206010014561 Emphysema Diseases 0.000 abstract 1
- 101000942118 Homo sapiens C-reactive protein Proteins 0.000 abstract 1
- 208000013616 Respiratory Distress Syndrome Diseases 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 238000007792 addition Methods 0.000 abstract 1
- 201000000028 adult respiratory distress syndrome Diseases 0.000 abstract 1
- 230000009435 amidation Effects 0.000 abstract 1
- 238000007112 amidation reaction Methods 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 208000006673 asthma Diseases 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 208000037976 chronic inflammation Diseases 0.000 abstract 1
- 230000006020 chronic inflammation Effects 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4737—C-reactive protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL12119197A IL121191A0 (en) | 1997-06-29 | 1997-06-29 | Synthetic peptides and pharmaceutical compositions comprising them |
| PCT/IL1998/000302 WO1999000418A1 (en) | 1997-06-29 | 1998-06-29 | Anti-inflammatory peptides derived from c-reactive protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE261990T1 true ATE261990T1 (de) | 2004-04-15 |
Family
ID=11070323
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98929610T ATE261990T1 (de) | 1997-06-29 | 1998-06-29 | Entzündungshemmende peptide des c-reaktiven proteins |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6528618B1 (de) |
| EP (1) | EP0996633B1 (de) |
| AT (1) | ATE261990T1 (de) |
| AU (1) | AU7929198A (de) |
| DE (1) | DE69822467T2 (de) |
| ES (1) | ES2218836T3 (de) |
| IL (2) | IL121191A0 (de) |
| WO (1) | WO1999000418A1 (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1237917A2 (de) * | 1999-11-19 | 2002-09-11 | Eli Lilly And Company | Derivate aus protein c |
| CN1216072C (zh) | 2001-07-13 | 2005-08-24 | 一泰医药研究(深圳)有限公司 | 序列号5的生物活性肽 |
| US7425545B2 (en) | 2001-07-25 | 2008-09-16 | Isis Pharmaceuticals, Inc. | Modulation of C-reactive protein expression |
| US6964950B2 (en) | 2001-07-25 | 2005-11-15 | Isis Pharmaceuticals, Inc. | Antisense modulation of C-reactive protein expression |
| IL161407A0 (en) | 2001-10-15 | 2004-09-27 | Chiron Corp | Treatment of severe pneumonia by administration of tissue factor pathway inhibitor (tfpi) |
| FI20012082A0 (fi) | 2001-10-26 | 2001-10-26 | Paeivi Liesi | Biologisesti aktiiviset peptidit hermovauroiden korjaamiseksi |
| US7226995B2 (en) * | 2003-10-23 | 2007-06-05 | Stc.Unm | Use of C-reactive protein to treat immune complex-mediated renal disease |
| US8304382B2 (en) * | 2006-07-21 | 2012-11-06 | Cristalia Productos Quimicos Farmaceuticos Ltda. | Anti-inflammatory and anti-allergic cyclic peptides |
| ES2678143T3 (es) | 2010-01-19 | 2018-08-09 | President And Fellows Of Harvard College | Opsonina obtenida por ingeniería genética para la detección y el tratamiento de microorganismos patógenos |
| EP2734843A2 (de) | 2011-07-18 | 2014-05-28 | President and Fellows of Harvard College | Manipulierte moleküle zur anzielung von mikroben und ihre verwendungen |
| EP2976642A4 (de) | 2013-03-15 | 2016-09-21 | Harvard College | Verfahren und zusammensetzungen zur verbesserung der erkennung und/oder aufnahme einer zieleinheit |
| US9988617B2 (en) | 2013-05-21 | 2018-06-05 | President And Fellows Of Harvard College | Engineered heme-binding compositions and uses thereof |
| EP3546474B1 (de) | 2013-12-18 | 2021-07-07 | President and Fellows of Harvard College | Crp-erfassung/-detektion von grampositiven bakterien |
| CN108289928B (zh) | 2015-08-06 | 2024-09-17 | 哈佛大学校长及研究员协会 | 改进的微生物-结合分子和其用途 |
-
1997
- 1997-06-29 IL IL12119197A patent/IL121191A0/xx unknown
-
1998
- 1998-06-29 WO PCT/IL1998/000302 patent/WO1999000418A1/en not_active Ceased
- 1998-06-29 EP EP98929610A patent/EP0996633B1/de not_active Expired - Lifetime
- 1998-06-29 AU AU79291/98A patent/AU7929198A/en not_active Abandoned
- 1998-06-29 US US09/446,868 patent/US6528618B1/en not_active Expired - Fee Related
- 1998-06-29 ES ES98929610T patent/ES2218836T3/es not_active Expired - Lifetime
- 1998-06-29 DE DE69822467T patent/DE69822467T2/de not_active Expired - Lifetime
- 1998-06-29 AT AT98929610T patent/ATE261990T1/de not_active IP Right Cessation
-
1999
- 1999-12-28 IL IL133769A patent/IL133769A/en not_active IP Right Cessation
-
2003
- 2003-02-27 US US10/373,794 patent/US7182945B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999000418A1 (en) | 1999-01-07 |
| ES2218836T3 (es) | 2004-11-16 |
| DE69822467D1 (de) | 2004-04-22 |
| IL121191A0 (en) | 1997-11-20 |
| AU7929198A (en) | 1999-01-19 |
| US7182945B2 (en) | 2007-02-27 |
| EP0996633A1 (de) | 2000-05-03 |
| US20030152564A1 (en) | 2003-08-14 |
| EP0996633B1 (de) | 2004-03-17 |
| US6528618B1 (en) | 2003-03-04 |
| DE69822467T2 (de) | 2005-03-24 |
| IL133769A (en) | 2006-06-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0996633 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |