ATE262337T1 - Azasteroidverbindung zur behandlung von alopezie, hirsutismus und seborrhoe - Google Patents

Azasteroidverbindung zur behandlung von alopezie, hirsutismus und seborrhoe

Info

Publication number
ATE262337T1
ATE262337T1 AT98933945T AT98933945T ATE262337T1 AT E262337 T1 ATE262337 T1 AT E262337T1 AT 98933945 T AT98933945 T AT 98933945T AT 98933945 T AT98933945 T AT 98933945T AT E262337 T1 ATE262337 T1 AT E262337T1
Authority
AT
Austria
Prior art keywords
hirsutism
aopezia
seborrhoe
treatment
azasteroid compound
Prior art date
Application number
AT98933945T
Other languages
English (en)
Inventor
Koichi Kojima
Takakazu Hamada
Shiroh Yosioka
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Application granted granted Critical
Publication of ATE262337T1 publication Critical patent/ATE262337T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT98933945T 1997-07-29 1998-07-27 Azasteroidverbindung zur behandlung von alopezie, hirsutismus und seborrhoe ATE262337T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP20313697 1997-07-29
PCT/JP1998/003337 WO1999006050A1 (en) 1997-07-29 1998-07-27 Remedial agent for baldness and other diseases

Publications (1)

Publication Number Publication Date
ATE262337T1 true ATE262337T1 (de) 2004-04-15

Family

ID=16469018

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98933945T ATE262337T1 (de) 1997-07-29 1998-07-27 Azasteroidverbindung zur behandlung von alopezie, hirsutismus und seborrhoe

Country Status (21)

Country Link
US (1) US6380179B1 (de)
EP (1) EP0998930B1 (de)
KR (1) KR20010022066A (de)
CN (1) CN1129433C (de)
AT (1) ATE262337T1 (de)
AU (1) AU733830B2 (de)
BR (1) BR9811293A (de)
CA (1) CA2298851A1 (de)
DE (1) DE69822636T2 (de)
DK (1) DK0998930T3 (de)
ES (1) ES2218840T3 (de)
HU (1) HUP0003159A3 (de)
ID (1) ID24566A (de)
IL (1) IL134199A0 (de)
NO (1) NO20000469L (de)
NZ (1) NZ502537A (de)
PL (1) PL338414A1 (de)
PT (1) PT998930E (de)
RU (1) RU2193887C2 (de)
TR (1) TR200000263T2 (de)
WO (1) WO1999006050A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2221703T3 (es) * 1997-02-26 2005-01-01 Sankyo Company Limited Compuesto azasteroide para el tratamiento o la prevencion del cancer de prostata.
US20050169870A1 (en) * 2004-02-02 2005-08-04 Schering Corporation Methods of modulating CD200
JP4956534B2 (ja) * 2005-06-24 2012-06-20 アリゾナ・ボード・オブ・リージェンツ・オン・ビハーフ・オブ・ザ・ユニバーシティ・オブ・アリゾナ 女性型脱毛症等の毛髪成長障害の治療方法とそのために有用な組成物
US20080108681A1 (en) * 2006-10-27 2008-05-08 Access Business Group International Llc Use of allantoin as a pro-collagen synthesis agent in cosmetic compositions
WO2011014649A1 (en) 2009-07-29 2011-02-03 Duke University Compositions and methods for inhibiting hair growth
MX2010012945A (es) * 2010-11-24 2012-05-24 Fidel Ojeda Gomez Una formula para el control y eliminacion de seborrea y alopecia en el cuero cabelludo.
RU2477155C2 (ru) * 2011-04-27 2013-03-10 Закрытое акционерное общество "Патент-Фарм" Способ лечения андрогенетической алопеции

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571817A (en) 1984-02-27 1996-11-05 Merck & Co., Inc. Methods of treating androgenic alopecia with finasteride [17β-N-mono-substituted-carbamoyl-4-aza-5-α-androst-1-en-ones]
US5516768A (en) 1990-03-16 1996-05-14 Smithkline Beecham Corporation Uncompetitive inhibition of steroid and 5α-reductose
IE76452B1 (en) * 1990-10-29 1997-10-22 Sankyo Co Azasteroid compounds for the treatment of prostatic hypertrophy their preparation and use
JP3030152B2 (ja) * 1992-02-03 2000-04-10 三共株式会社 ４−アザステロイド化合物
US5278159A (en) * 1992-10-06 1994-01-11 Merck & Co., Inc. Aryl ester derivatives of 3-oxo-4-aza-androstane 17-β-carboxylates as 5-α-reductase inhibitors
US5486511A (en) * 1993-05-25 1996-01-23 Merrell Dow Pharmaceuticals Inc. 4-amino-17β-(cyclopropyloxy)androst-4-en-3-one, 4-amino-17β-(cyclopropylamino)androst-4-en-3-one and related compounds as C17-20 lyase and 5α-reductase
TW382595B (en) 1993-10-15 2000-02-21 Merck & Co Inc Pharmaceutical composition for use in arresting and reversing androgenic alopecia
JPH0873492A (ja) * 1994-06-28 1996-03-19 Sankyo Co Ltd アザステロイド類
US5629007A (en) 1995-03-21 1997-05-13 Eli Lilly And Company Method of preventing prostatic cancer development
US5635197A (en) 1995-03-21 1997-06-03 Eli Lilly And Company Treatment and prevention of prostatic cancer metastasis
CA2231434A1 (en) 1995-09-27 1997-04-03 Glenn J. Gormley Method of preventing androgenetic alopecia with 5-.alpha. reductase inhibitors
PT923942E (pt) * 1996-02-05 2002-03-28 Sankyo Co Preparacao inibidora de 5alfa-reductase para administracao oral um processo para producao da mesma e sua utilizacao
ES2221703T3 (es) * 1997-02-26 2005-01-01 Sankyo Company Limited Compuesto azasteroide para el tratamiento o la prevencion del cancer de prostata.
US6093722A (en) 1997-02-26 2000-07-25 Sankyo Company, Limited Method for treating prostate cancer

Also Published As

Publication number Publication date
NO20000469L (no) 2000-03-28
IL134199A0 (en) 2001-04-30
DK0998930T3 (da) 2004-04-26
ES2218840T3 (es) 2004-11-16
EP0998930B1 (de) 2004-03-24
AU733830B2 (en) 2001-05-24
US6380179B1 (en) 2002-04-30
DE69822636T2 (de) 2005-01-05
CA2298851A1 (en) 1999-02-11
CN1271285A (zh) 2000-10-25
AU8358598A (en) 1999-02-22
WO1999006050A1 (en) 1999-02-11
RU2193887C2 (ru) 2002-12-10
HK1027290A1 (en) 2001-01-12
KR20010022066A (ko) 2001-03-15
ID24566A (id) 2000-07-27
NZ502537A (en) 2002-11-26
PT998930E (pt) 2004-05-31
CN1129433C (zh) 2003-12-03
EP0998930A1 (de) 2000-05-10
HUP0003159A2 (hu) 2001-04-28
EP0998930A4 (de) 2002-06-12
HUP0003159A3 (en) 2001-07-30
NO20000469D0 (no) 2000-01-28
DE69822636D1 (de) 2004-04-29
BR9811293A (pt) 2000-08-29
PL338414A1 (en) 2000-11-06
TR200000263T2 (tr) 2000-09-21

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