ATE263172T1 - Oxazolidinone mit tricyclische substituente als antibacterielle mittel - Google Patents

Oxazolidinone mit tricyclische substituente als antibacterielle mittel

Info

Publication number
ATE263172T1
ATE263172T1 AT96939496T AT96939496T ATE263172T1 AT E263172 T1 ATE263172 T1 AT E263172T1 AT 96939496 T AT96939496 T AT 96939496T AT 96939496 T AT96939496 T AT 96939496T AT E263172 T1 ATE263172 T1 AT E263172T1
Authority
AT
Austria
Prior art keywords
oxazolidinone
antibacterial agents
organisms
tricyclic substituents
tricyclic
Prior art date
Application number
AT96939496T
Other languages
English (en)
Inventor
Richard C Thomas
Gary J Cleek
Douglas K Hutchinson
Hiroyoshi Yamada
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Application granted granted Critical
Publication of ATE263172T1 publication Critical patent/ATE263172T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT96939496T 1995-11-17 1996-11-05 Oxazolidinone mit tricyclische substituente als antibacterielle mittel ATE263172T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US737195P 1995-11-17 1995-11-17
PCT/US1996/017120 WO1997019089A1 (en) 1995-11-17 1996-11-05 Oxazolidinone antibacterial agent with tricyclic substituents

Publications (1)

Publication Number Publication Date
ATE263172T1 true ATE263172T1 (de) 2004-04-15

Family

ID=21725778

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96939496T ATE263172T1 (de) 1995-11-17 1996-11-05 Oxazolidinone mit tricyclische substituente als antibacterielle mittel

Country Status (12)

Country Link
US (2) US5922707A (de)
EP (1) EP0874852B1 (de)
JP (1) JP2000500489A (de)
AT (1) ATE263172T1 (de)
AU (1) AU7665196A (de)
DE (1) DE69632074T2 (de)
DK (1) DK0874852T3 (de)
ES (1) ES2217329T3 (de)
PT (1) PT874852E (de)
TW (1) TW426683B (de)
WO (1) WO1997019089A1 (de)
ZA (1) ZA968661B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.
GB9601666D0 (en) * 1996-01-27 1996-03-27 Zeneca Ltd Chemical compounds
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
GB9609919D0 (en) 1996-05-11 1996-07-17 Zeneca Ltd Chemical compounds
CN1265660A (zh) * 1997-08-15 2000-09-06 辉瑞产品公司 2－(4－芳基或杂芳基－哌嗪－1－基甲基)－1h－吲哚衍生物
GB9717804D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9717807D0 (en) 1997-08-22 1997-10-29 Zeneca Ltd Chemical compounds
GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
DE19802235A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Mit tricyclischen Indolen substituierte Oxazolidinone
DE19802239A1 (de) * 1998-01-22 1999-07-29 Bayer Ag Neue mit Bicyclen substituierte Oxazolidinone
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6239152B1 (en) 1998-01-23 2001-05-29 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
DE19805117A1 (de) * 1998-02-09 1999-08-12 Bayer Ag Neue Oxazolidinone mit azolhaltigen Tricyclen
CN1311787A (zh) 1998-06-05 2001-09-05 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物
MY122454A (en) * 1998-06-05 2006-04-29 Upjohn Co Use of oxazolidinones for the preparation of a medicament for transdermal delivery
US6673799B1 (en) 1998-09-22 2004-01-06 Yamanouchi Pharmaceutical Co. Ltd. Cyanophenyl derivative
AU4224699A (en) 1999-01-27 2000-08-18 Pharmacia & Upjohn Company Assays for modulators of elongation factor p activity
MXPA01012167A (es) 1999-05-27 2002-06-21 Upjohn Co Nuevas oxazolidinonas biciclicas como agentes antibacterianos.
GB9928568D0 (en) 1999-12-03 2000-02-02 Zeneca Ltd Chemical compounds
GB0009803D0 (en) * 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
DE60304360T2 (de) 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
US7141570B2 (en) 2002-11-21 2006-11-28 Pharmacia & Upjohn Company N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
JP2006516991A (ja) * 2003-02-07 2006-07-13 ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー 抗菌剤
EP1661898A4 (de) * 2003-08-29 2009-04-15 Takeda Pharmaceutical Bicyclische piperazinverbindung und deren verwendung
AR057828A1 (es) * 2005-09-29 2007-12-19 Astrazeneca Ab Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
MX2008009475A (es) * 2006-01-23 2008-10-20 Amira Pharmaceuticals Inc Inhibidores triciclicos de 5-lipoxigenasa.
CN110734454B (zh) * 2016-12-12 2021-08-17 石药集团中奇制药技术（石家庄）有限公司 一类含有三环杂芳基的化合物
CN116675704A (zh) * 2020-12-21 2023-09-01 深圳市祥根生物医药有限公司 一种吡咯衍生物及其制备方法和用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883522A (en) * 1974-02-11 1975-05-13 Riker Laboratories Inc Substituted pyrido(1,2,3-de)-1,4-benzoxazines
US4080499A (en) * 1976-12-20 1978-03-21 1 Substituted 7,8-dihydro-6H-(1,2,5)thiadiazolo(3',4'-5,6)pyrazino(2,3-b)(1,4)oxazines
US5039690A (en) * 1987-10-09 1991-08-13 Du Pont Merck Pharmaceutical Company Aminomethyl oxooxazolidinyl oxa or thia cycloalkylbenzene derivatives useful as antibacterial agents
WO1990002744A1 (en) * 1988-09-15 1990-03-22 The Upjohn Company In position 3 substituted-5-beta-amidomethyl-oxazolidin-2-ones
US5225565A (en) * 1988-09-15 1993-07-06 The Upjohn Company Antibacterial 3-(fused-ring substituted)phenyl-5β-amidomethyloxazolidin-2-ones
JP3512110B2 (ja) * 1992-02-13 2004-03-29 ファルマシア・アンド・アップジョン・カンパニー ベンゾジアゼピン受容体結合剤として有用な４−オキソ−および４Ｈ−イミダゾ（５，１−ｃ）（１，４）ベンゾオキサジン類
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
US5668286A (en) * 1994-03-15 1997-09-16 Pharmacia & Upjohn Company Oxazolidinone derivatives and pharmaceutical compositions containing them
NZ295528A (en) * 1994-11-15 1999-03-29 Upjohn Co Bicyclic oxazine and thiazine oxazolidinone antibacterials
ZA968661B (en) * 1995-11-17 1998-04-14 Upjohn Co Oxazolidinone antibacterial agent with tricyclic substituents.

Also Published As

Publication number Publication date
PT874852E (pt) 2004-08-31
DK0874852T3 (da) 2004-06-07
EP0874852B1 (de) 2004-03-31
AU7665196A (en) 1997-06-11
US5955460A (en) 1999-09-21
ES2217329T3 (es) 2004-11-01
EP0874852A1 (de) 1998-11-04
JP2000500489A (ja) 2000-01-18
TW426683B (en) 2001-03-21
DE69632074T2 (de) 2005-01-20
US5922707A (en) 1999-07-13
WO1997019089A1 (en) 1997-05-29
DE69632074D1 (de) 2004-05-06
ZA968661B (en) 1998-04-14

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