ATE263836T1 - Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür - Google Patents

Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür

Info

Publication number
ATE263836T1
ATE263836T1 AT95900453T AT95900453T ATE263836T1 AT E263836 T1 ATE263836 T1 AT E263836T1 AT 95900453 T AT95900453 T AT 95900453T AT 95900453 T AT95900453 T AT 95900453T AT E263836 T1 ATE263836 T1 AT E263836T1
Authority
AT
Austria
Prior art keywords
proteins
chimeric
chimere
proteins including
borrelia
Prior art date
Application number
AT95900453T
Other languages
English (en)
Inventor
John J Dunn
Benjamin J Luft
Original Assignee
Brookhaven Science Ass Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/235,836 external-priority patent/US6248562B1/en
Application filed by Brookhaven Science Ass Llc filed Critical Brookhaven Science Ass Llc
Application granted granted Critical
Publication of ATE263836T1 publication Critical patent/ATE263836T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/20—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT95900453T 1993-11-01 1994-10-27 Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür ATE263836T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14819193A 1993-11-01 1993-11-01
US08/235,836 US6248562B1 (en) 1993-11-01 1994-04-29 Chimeric proteins comprising borrelia polypeptides and uses therefor
PCT/US1994/012352 WO1995012676A1 (en) 1993-11-01 1994-10-27 Chimeric proteins comprising borrelia polypeptides: uses therefor

Publications (1)

Publication Number Publication Date
ATE263836T1 true ATE263836T1 (de) 2004-04-15

Family

ID=26845620

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95900453T ATE263836T1 (de) 1993-11-01 1994-10-27 Chimere proteine, welche borrelia polypeptide beinhalten, verwendungen dafür

Country Status (10)

Country Link
EP (1) EP0726955B1 (de)
AT (1) ATE263836T1 (de)
AU (1) AU8127494A (de)
CA (1) CA2175567C (de)
DE (1) DE69433690T2 (de)
DK (1) DK0726955T3 (de)
ES (1) ES2219657T3 (de)
IL (1) IL111479A0 (de)
PT (1) PT726955E (de)
WO (1) WO1995012676A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6676942B1 (en) * 1991-08-15 2004-01-13 Smithkline Beecham Biologicals (S.A.) Osp a proteins of Borrelia burgdorferi subgroups, encoding genes and vaccines
US7008625B2 (en) 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
CA2193870C (en) * 1995-12-25 2000-07-18 Nobuyuki Ise Treponema pallidum fused antigen and assay for anti-treponema pallidum antibodies using the same fused antigen
DE19632862B4 (de) 1996-08-14 2006-08-03 Mikrogen Molekularbiologische Entwicklungs-Gmbh Immunologisch aktive Proteine von Borrelia burgdorferi, dafür kodierende Nukleinsäuren sowie deren Verwendung in Testkits und als Impfstoffe
WO1999012960A2 (en) * 1997-09-10 1999-03-18 Symbicom Ab P13 ANTIGENS FROM $i(BORRELIA)
DE19847142A1 (de) * 1998-10-13 2000-04-27 Max Planck Gesellschaft Testkit zur Diagnose von Borreliosen und neue Borrelia-Antigene für die Impfstoffentwicklung
US7060281B1 (en) 1999-06-18 2006-06-13 Research Foundation Of The State University Of New York Groups of barrelia burgdorferi and borrelia afzelii that cause lyme disease in humans
ATE381575T1 (de) 2000-08-18 2008-01-15 Univ New York State Res Found Veränderte borrelia burgdorferi ospa
AU2001281145A1 (en) * 2000-08-18 2002-03-04 Brookhaven Sciences Associates, Llc Recombinant constructs of borrelia burgdorferi
EP1939294A1 (de) * 2000-08-18 2008-07-02 Research Foundation Of State University Of New York Rekombinante Konstrukte von Borrelia Burgdorferi
EP1865062A3 (de) * 2000-08-18 2008-01-09 Research Foundation Of State University Of New York Verändertes OspA der Borrelia burgdorferi
WO2008116468A2 (en) 2007-03-26 2008-10-02 Dako Denmark A/S Mhc peptide complexes and uses thereof in infectious diseases
EP3620465B1 (de) 2007-07-03 2025-02-19 Dako Denmark A/S Verbesserte verfahren zur herstellung, markierung und verwendung von mhc-multimeren
US10611818B2 (en) 2007-09-27 2020-04-07 Agilent Technologies, Inc. MHC multimers in tuberculosis diagnostics, vaccine and therapeutics
DK2254592T3 (da) 2008-02-28 2019-09-09 Dako Denmark As MHC-multimerer til Borrelia-diagnostik og sygdom
WO2010009735A2 (en) 2008-07-23 2010-01-28 Dako Denmark A/S Combinatorial analysis and repair
GB0817244D0 (en) 2008-09-20 2008-10-29 Univ Cardiff Use of a protein kinase inhibitor to detect immune cells, such as T cells
WO2010037402A1 (en) 2008-10-02 2010-04-08 Dako Denmark A/S Molecular vaccines for infectious disease
US11992518B2 (en) 2008-10-02 2024-05-28 Agilent Technologies, Inc. Molecular vaccines for infectious disease
AU2011252844B2 (en) * 2010-05-14 2014-07-03 Baxalta GmbH Chimeric OspA genes, proteins, and methods of use thereof
AU2013293448A1 (en) 2012-07-27 2015-02-05 Baxalta GmbH Compositions comprising chimeric OspA molecules and methods of use thereof
CZ2014320A3 (cs) * 2014-05-09 2015-11-18 VÝZKUMNÝ ÚSTAV VETERINÁRNÍHO LÉKAŘSTVÍ, v.v.i. Polyepitopový antigen, vakcinační konstrukt a vakcína pro prevenci lymeské boreliózy
JP2017531657A (ja) * 2014-10-07 2017-10-26 ザ リサーチ ファンデーション フォー ザ ステート ユニバーシティ オブ ニューヨーク 組換えボレリアタンパク質およびその使用のための方法
WO2020127222A2 (en) 2018-12-17 2020-06-25 Immudex Aps Panel comprising borrelia mhc multimers
US12364744B2 (en) * 2020-11-25 2025-07-22 Lankenau Institute For Medical Research Methods and compositions for the diagnosis, prophylaxis and treatment of Lyme disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05501113A (ja) * 1990-03-05 1993-03-04 アメリカ合衆国 ボレリア　ブルグドルフェリの抗原性タンパク質
ES2194010T3 (es) * 1991-10-22 2003-11-16 Symbicom Ab Mejoras en el diagnostico y profilaxis de la borrelia burgdorferi.
AU6366894A (en) * 1993-03-11 1994-09-26 Regents Of The University Of California, The Methods, compositions, and kits for diagnosing lyme disease

Also Published As

Publication number Publication date
DK0726955T3 (da) 2004-08-09
ES2219657T3 (es) 2004-12-01
WO1995012676A1 (en) 1995-05-11
DE69433690D1 (de) 2004-05-13
EP0726955B1 (de) 2004-04-07
IL111479A0 (en) 1994-12-29
CA2175567C (en) 2010-08-10
PT726955E (pt) 2004-08-31
CA2175567A1 (en) 1995-05-11
EP0726955A1 (de) 1996-08-21
DE69433690T2 (de) 2005-03-10
AU8127494A (en) 1995-05-23

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