ATE263971T1 - Methode zum nachweis von veränderungen zellulärer komponenten - Google Patents

Methode zum nachweis von veränderungen zellulärer komponenten

Info

Publication number
ATE263971T1
ATE263971T1 AT00900695T AT00900695T ATE263971T1 AT E263971 T1 ATE263971 T1 AT E263971T1 AT 00900695 T AT00900695 T AT 00900695T AT 00900695 T AT00900695 T AT 00900695T AT E263971 T1 ATE263971 T1 AT E263971T1
Authority
AT
Austria
Prior art keywords
state
bound
macromolecular component
sensor molecule
molecule
Prior art date
Application number
AT00900695T
Other languages
English (en)
Inventor
Philippe Igor Henri Bastiaens
Peter Joseph Jacques Parker
Original Assignee
Cancer Rec Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Rec Tech Ltd filed Critical Cancer Rec Tech Ltd
Application granted granted Critical
Publication of ATE263971T1 publication Critical patent/ATE263971T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43595—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from coelenteratae, e.g. medusae

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Materials By The Use Of Fluid Adsorption Or Reactions (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Burglar Alarm Systems (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
AT00900695T 1999-01-19 2000-01-19 Methode zum nachweis von veränderungen zellulärer komponenten ATE263971T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9901072.0A GB9901072D0 (en) 1999-01-19 1999-01-19 Methods for detecting changes to a macromolecular component of a cell
PCT/GB2000/000118 WO2000043780A1 (en) 1999-01-19 2000-01-19 Methods for detecting changes to cellular components

Publications (1)

Publication Number Publication Date
ATE263971T1 true ATE263971T1 (de) 2004-04-15

Family

ID=10846082

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00900695T ATE263971T1 (de) 1999-01-19 2000-01-19 Methode zum nachweis von veränderungen zellulärer komponenten

Country Status (7)

Country Link
EP (1) EP1145004B1 (de)
JP (1) JP2002535655A (de)
AT (1) ATE263971T1 (de)
AU (1) AU3062300A (de)
DE (1) DE60009661D1 (de)
GB (1) GB9901072D0 (de)
WO (1) WO2000043780A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0007915D0 (en) * 2000-03-31 2000-05-17 Univ Bristol Protein kinase assay
AU2001294872A1 (en) * 2000-09-28 2002-04-08 Cellomics, Inc. Methods and reagents for live-cell gene expression quantification
AT410601B (de) * 2000-12-29 2003-06-25 Hoffmann La Roche Sensor zur lumineszenz-optischen bestimmung eines analyten sowie reagens, das nach dem fret-prinzip arbeitet
WO2002077623A1 (fr) * 2001-03-23 2002-10-03 Japan Science And Technology Corporation Sonde pour visualiser la phosphorylation/dephosphorylation de proteines et procede de detection et de quantification de la phosphorylation/dephosphorylation de proteines
FR2826666B1 (fr) * 2001-07-02 2004-07-02 Novaleads Procede de selection d'agents bio-actifs par couplage de luminescence et systeme cellulaire vivant pour la mise en oeuvre de ce procede
EP1499885B1 (de) 2001-08-01 2009-10-21 Cellomics, Inc. Neue fusionsproteine und molekulare bindungsassays
WO2003029796A1 (en) * 2001-09-28 2003-04-10 Ciencia, Incorporated Method to improve sensitivity of molecular binding assays using phase-sensitive luminescence detection
GB0208989D0 (en) * 2002-04-19 2002-05-29 Amersham Biosciences Uk Ltd Methods for measuring enzyme activity
WO2005019811A2 (en) 2003-08-26 2005-03-03 Blueshift Biotechnologies, Inc. Time dependent fluorescence measurements
EP1689887B1 (de) 2003-10-21 2012-03-21 Orion Genomics, LLC Verfahren zur quantitativen bestimmung der methylierungsdichte in einem dna-locus
US7141378B2 (en) 2004-07-02 2006-11-28 Blueshift Biotechnologies, Inc. Exploring fluorophore microenvironments
WO2007059297A2 (en) * 2005-11-16 2007-05-24 Carnegie Institution Of Washington Multimeric biosensors and methods of using the same
BRPI0717416A2 (pt) 2006-09-21 2013-11-12 Prometheus Lab Inc Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
EP2087355B1 (de) * 2006-11-27 2014-09-24 Cisbio Bioassays Verfahren zum nachweis posttranslationaler modifikationen
EP2169404B1 (de) * 2007-06-18 2016-01-27 Chugai Seiyaku Kabushiki Kaisha VERFAHREN ZUR MESSUNG DER BINDUNGSAKTIVITÄT EINES ANTIKÖRPERS MIT EINEM ANTIGEN UND MIT EINEM Fc-REZEPTOR
NZ582618A (en) 2007-07-13 2012-07-27 Prometheus Lab Inc Drug selection for lung cancer therapy using antibody-based arrays
EP2196794A4 (de) * 2007-08-30 2014-04-02 Mitsui Shipbuilding Eng Fret-nachweisverfahren und -vorrichtung
ES2553390T3 (es) 2008-02-25 2015-12-09 Nestec S.A. Método para la detección de receptores truncados intracelulares
JP5795311B2 (ja) 2009-07-15 2015-10-14 ネステク ソシエテ アノニム 抗体ベースのアレイを使用する胃癌療法のための薬物選択
US8950687B2 (en) 2010-09-21 2015-02-10 Honeywell International Inc. Remote control of an HVAC system that uses a common temperature setpoint for both heat and cool modes
US9719995B2 (en) 2011-02-03 2017-08-01 Pierian Holdings, Inc. Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling
KR101851425B1 (ko) 2011-09-02 2018-04-23 네스텍 소시에테아노님 치료 효능 결정을 위한 신호 경로 단백질의 프로파일링
CN108603037B (zh) 2015-12-10 2020-11-17 希望之城 细胞穿透花青偶联抗体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739357D1 (de) * 1996-06-04 2009-05-28 Univ Utah Res Found Überwachung der hybridisierung während pcr
WO1998045704A2 (en) * 1997-04-07 1998-10-15 Bioimage A/S A method for extracting quantitative information relating to an influence on a cellular response

Also Published As

Publication number Publication date
JP2002535655A (ja) 2002-10-22
EP1145004A1 (de) 2001-10-17
AU3062300A (en) 2000-08-07
EP1145004B1 (de) 2004-04-07
GB9901072D0 (en) 1999-03-10
DE60009661D1 (de) 2004-05-13
WO2000043780A1 (en) 2000-07-27

Similar Documents

Publication Publication Date Title
DE60009661D1 (de) Methode zum nachweis von veränderungen zellulärer komponenten
DE69840146D1 (de) Fluoreszenzprotein-sensoren zur erkennung von analyten
ATE226323T1 (de) Nachweisverfahren mit hilfe von fluoreszent- energietransferliganden auf lipidfilmen
WO2002044720A3 (en) Membrane molecule indicator compositions and methods
WO2005029033A3 (en) Cyanide sensing compounds and uses thereof
CA2573749A1 (en) Immunological test element with improved control zone
ATE394677T1 (de) Fret proben und verfahren zur erkennung aufeinander einwirkeneden moleküle
DE60038127D1 (de) Methoden und syteme zur überwachung intrazellulärer bindereaktionen
DK0716740T3 (da) Fremgangsmåde til aktivering af polyanioniske, fluorescerende farvestoffer i medier med lav dielektricitet ved hjælp af kvaternære oniumforbindelser
ID27972A (id) Antibodi-antibodi untuk mendeteksi berbagai mikroorganisme
WO2003040670A3 (en) Method of identifying energy transfer sensors for analytes
TW200704778A (en) Screening using polarization anisotropy in fret emissions
ATE555387T1 (de) Tests der molekularen oder subzellulären nähe unter verwendung von depolarisierung nach resonanzenergietransfer (daret)
CA2397545A1 (en) Method of detecting dna by dna hybridization method with the use of fluorescent resonance energy transfer
EP2221385A3 (de) Deubiquinations-Assays
DE69919143D1 (de) Nukleinsäure hybridisierung-testverfahren in lösung
WO2008078526A1 (ja) 蛍光共鳴エネルギー移動を用いたdnaとdna結合性タンパク質の相互作用の検出方法
WO2008123180A1 (ja) 標的物質の検出方法、並びに、これに用いるタグ、dna、ベクター、プローブ及び検出キット
ATE405837T1 (de) Festphase immunochromatographische testverfahren
ATE466884T1 (de) Holo-transcobalamin bindungspartner und ihre verwendung in cobalamintest
DE59907982D1 (de) Verfahren zum Nachweis einer bei Apoptose aktivierten Protease
DK1057021T3 (da) Fremgangsmåde til måling af totalanalyt
ATE354090T1 (de) Verfahren zum bestimmen von crp mit hilfe von phosphorylcholin
ATE396404T1 (de) Verfahren zum nachweis biologischer moleküle
ATE533053T1 (de) Nicht-elispot-test

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties