ATE264689T1 - Herstellung von kollagen - Google Patents

Herstellung von kollagen

Info

Publication number: ATE264689T1
Authority: AT; Austria
Prior art keywords: collagen; contacting; delipidated; phosphorylation; purified
Prior art date: 1997-01-13

Application number

AT98902442T

Other languages

English (en)

Inventor

Subramanian Gunasekaran

Original Assignee

Nova Gen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-01-13

Filing date

1998-01-12

Publication date

2004-05-15

1998-01-12 Application filed by Nova Gen Inc filed Critical Nova Gen Inc

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE264689T1 publication Critical patent/ATE264689T1/de

Links

102000008186 Collagen Human genes 0.000 title abstract 12
108010035532 Collagen Proteins 0.000 title abstract 12
229920001436 collagen Polymers 0.000 title abstract 12
108091005804 Peptidases Proteins 0.000 abstract 4
102000035195 Peptidases Human genes 0.000 abstract 4
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
230000026731 phosphorylation Effects 0.000 abstract 3
238000006366 phosphorylation reaction Methods 0.000 abstract 3
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
239000003638 chemical reducing agent Substances 0.000 abstract 2
239000003795 chemical substances by application Substances 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
108090000526 Papain Proteins 0.000 abstract 1
239000004365 Protease Substances 0.000 abstract 1
239000004599 antimicrobial Substances 0.000 abstract 1
239000003443 antiviral agent Substances 0.000 abstract 1
229940121357 antivirals Drugs 0.000 abstract 1
230000015961 delipidation Effects 0.000 abstract 1
VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 abstract 1
238000001035 drying Methods 0.000 abstract 1
239000000835 fiber Substances 0.000 abstract 1
239000003102 growth factor Substances 0.000 abstract 1
230000023597 hemostasis Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
229940055729 papain Drugs 0.000 abstract 1
235000019834 papain Nutrition 0.000 abstract 1
229940024999 proteolytic enzymes for treatment of wounds and ulcers Drugs 0.000 abstract 1
239000012279 sodium borohydride Substances 0.000 abstract 1
229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
229910052979 sodium sulfide Inorganic materials 0.000 abstract 1
GRVFOGOEDUUMBP-UHFFFAOYSA-N sodium sulfide (anhydrous) Chemical group [Na+].[Na+].[S-2] GRVFOGOEDUUMBP-UHFFFAOYSA-N 0.000 abstract 1
UGTZMIPZNRIWHX-UHFFFAOYSA-K sodium trimetaphosphate Chemical compound [Na+].[Na+].[Na+].[O-]P1(=O)OP([O-])(=O)OP([O-])(=O)O1 UGTZMIPZNRIWHX-UHFFFAOYSA-K 0.000 abstract 1
238000002054 transplantation Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Dermatology (AREA)
Diabetes (AREA)
Hematology (AREA)
Materials For Medical Uses (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

AT98902442T 1997-01-13 1998-01-12 Herstellung von kollagen ATE264689T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/782,138 US5814328A (en)	1997-01-13	1997-01-13	Preparation of collagen using papain and a reducing agent
PCT/US1998/000371 WO1998030225A1 (en)	1997-01-13	1998-01-12	Preparation of collagen

Publications (1)

Publication Number	Publication Date
ATE264689T1 true ATE264689T1 (de)	2004-05-15

Family

ID=25125107

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98902442T ATE264689T1 (de)	1997-01-13	1998-01-12	Herstellung von kollagen

Country Status (8)

Country	Link
US (3)	US5814328A (de)
EP (1)	EP1007065B1 (de)
JP (1)	JP4025897B2 (de)
AT (1)	ATE264689T1 (de)
AU (1)	AU740950B2 (de)
CA (1)	CA2277896C (de)
DE (1)	DE69823361T2 (de)
WO (1)	WO1998030225A1 (de)

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ54899A3 (cs)	1996-08-23	1999-08-11	Cook Biotech, Incorporated	Štěpová protéza, materiály s ní spojené a způsoby její výroby
US20030203008A1 (en) *	1997-01-13	2003-10-30	Subramanian Gunasekaran	Preparation of collagen
US5814328A (en) *	1997-01-13	1998-09-29	Gunasekaran; Subramanian	Preparation of collagen using papain and a reducing agent
JP3869142B2 (ja) *	1999-01-29	2007-01-17	独立行政法人科学技術振興機構	中空糸状シリカとその製造方法
US6372494B1 (en)	1999-05-14	2002-04-16	Advanced Tissue Sciences, Inc.	Methods of making conditioned cell culture medium compositions
CA2452033C (en) *	2001-06-28	2011-11-08	Cook Biotech Incorporated	Graft prosthesis devices containing renal capsule collagen
US6478825B1 (en)	2001-11-28	2002-11-12	Osteotech, Inc.	Implant, method of making same and use of the implant for the treatment of bone defects
JP4698932B2 (ja) *	2002-04-08	2011-06-08	肇一柴	ポリリン酸と水溶性コラーゲンの複合体材料とその製造方法
US20040002444A1 (en) *	2002-04-08	2004-01-01	Toshikazu Shiba	Polyphosphate-water soluble collagen complexes and process for preparation thereof
WO2003092604A2 (en) *	2002-05-02	2003-11-13	Purdue Research Foundation	Vascularization enhanced graft constructs
AUPS242702A0 (en) *	2002-05-21	2002-06-13	Colltech Australia Limited	Improved method for the extraction and purification of collagen
CA2525994C (en)	2002-06-24	2012-10-16	Tufts University	Silk biomaterials and methods of use thereof
CN100394989C (zh) *	2002-11-15	2008-06-18	华沙整形外科股份有限公司	包含微粒状基于胶原材料的组合物的制药应用和包含所述组合物的滑膜关节
CA2562415C (en)	2003-04-10	2015-10-27	Tufts University	Concentrated aqueous silk fibroin solutions free of organic solvents and uses thereof
US7993578B2 (en) *	2004-10-29	2011-08-09	Depuy Spine, Inc.	Methods and kits for aseptic filling of products
WO2007040574A2 (en) *	2004-12-16	2007-04-12	Regents Of The University Of Minnesota	Biomimetic nanocomposite
JP4738005B2 (ja) *	2005-02-02	2011-08-03	株式会社高研	魚皮の前処理方法
KR100676285B1 (ko) *	2005-03-11	2007-01-30	세원셀론텍(주)	동물의 다양한 조직으로부터의 콜라겐 분리방법 및 콜라겐 용액의 제조방법 그리고 이를 이용하여 생산한 매트릭스
US7485323B2 (en) *	2005-05-31	2009-02-03	Gelita Ag	Process for making a low molecular weight gelatine hydrolysate and gelatine hydrolysate compositions
US20070038298A1 (en) *	2005-06-30	2007-02-15	Sulner Joseph W	Repair of tympanic membrane using placenta derived collagen biofabric
EP1919500A2 (de) *	2005-07-13	2008-05-14	Anthrogenesis Corporation	Behandlung von beingeschwüren mit kollagen-biogewebe aus plazenta
EP1919365A2 (de) *	2005-07-13	2008-05-14	Anthrogenesis Corporation	Okular-plug aus kollagen-biogewebe aus plazenta
CA2518298A1 (fr) *	2005-09-06	2007-03-06	Chaimed Technologies Inc.	Polymeres biodegradables, leur preparation et leur usage pour la fabrication de pansements
US20070190165A1 (en) *	2005-10-21	2007-08-16	Brey Eric M	Tissue-specific basement membrane gels
US20070117176A1 (en) *	2005-11-18	2007-05-24	Srinivasan Aishwarya	Process for the extraction of atelopeptide collagen from a collagenous source by microbial treatment
US8690957B2 (en)	2005-12-21	2014-04-08	Warsaw Orthopedic, Inc.	Bone graft composition, method and implant
WO2008021391A1 (en) *	2006-08-15	2008-02-21	Anthrogenesis Corporation	Umbilical cord biomaterial for medical use
US7491541B2 (en) *	2006-09-21	2009-02-17	Kci Licensing, Inc.	Method for quantitation of collagen in tissue
WO2008118133A2 (en)	2006-09-26	2008-10-02	Trustees Of Tufts College	Silk microspheres for encapsulation and controlled release
US20080131522A1 (en) *	2006-10-03	2008-06-05	Qing Liu	Use of placental biomaterial for ocular surgery
US8071135B2 (en)	2006-10-04	2011-12-06	Anthrogenesis Corporation	Placental tissue compositions
NZ597223A (en)	2006-10-06	2013-09-27	Anthrogenesis Corp	Native (telopeptide) placental collagen compositions
US20080260794A1 (en) *	2007-02-12	2008-10-23	Lauritzen Nels J	Collagen products and methods for producing collagen products
US9056151B2 (en) *	2007-02-12	2015-06-16	Warsaw Orthopedic, Inc.	Methods for collagen processing and products using processed collagen
AU2008219006B2 (en) *	2007-02-20	2013-04-18	Shriners Hospitals For Children	In vivo hydraulic fixation including bio-rivets using biocompatible expandable fibers
WO2008106485A2 (en)	2007-02-27	2008-09-04	Trustees Of Tufts College	Tissue-engineered silk organs
US20090004455A1 (en) *	2007-06-27	2009-01-01	Philippe Gravagna	Reinforced composite implant
AU2008274947A1 (en) *	2007-07-12	2009-01-15	The University Of North Carolina At Chapel Hill	Formable bioceramics
WO2009023615A1 (en)	2007-08-10	2009-02-19	Trustees Of Tufts College	Tubular silk compositions and methods of use thereof
US9308068B2 (en)	2007-12-03	2016-04-12	Sofradim Production	Implant for parastomal hernia
US9242026B2 (en)	2008-06-27	2016-01-26	Sofradim Production	Biosynthetic implant for soft tissue repair
MY160866A (en)	2008-12-23	2017-03-31	Univ Putra Malaysia	Collagen extraction from aquatic animals
FR2949688B1 (fr)	2009-09-04	2012-08-24	Sofradim Production	Tissu avec picots revetu d'une couche microporeuse bioresorbable
FR2951549B1 (fr)	2009-10-15	2013-08-23	Olivier Schussler	Procede d'obtention de bioprotheses medicales implantables
US8460691B2 (en)	2010-04-23	2013-06-11	Warsaw Orthopedic, Inc.	Fenestrated wound repair scaffold
US8790699B2 (en)	2010-04-23	2014-07-29	Warsaw Orthpedic, Inc.	Foam-formed collagen strand
CN105671018A (zh) *	2010-08-31	2016-06-15	天野酶制品株式会社	使用了酶的蛋壳膜的溶解方法
CN101948900B (zh) *	2010-10-09	2013-06-12	上海阿敏生物技术有限公司	一种从牛软骨提取水解胶原蛋白的方法
FR2972626B1 (fr)	2011-03-16	2014-04-11	Sofradim Production	Prothese comprenant un tricot tridimensionnel et ajoure
WO2012145652A1 (en)	2011-04-20	2012-10-26	Trustees Of Tufts College	Dynamic silk coatings for implantable devices
US9694106B2 (en)	2011-07-11	2017-07-04	Mimedx Group, Inc.	Synthetic collagen threads for cosmetic uses including skin wrinkle treatments and associated methods
FR2977789B1 (fr)	2011-07-13	2013-07-19	Sofradim Production	Prothese pour hernie ombilicale
FR2977790B1 (fr)	2011-07-13	2013-07-19	Sofradim Production	Prothese pour hernie ombilicale
CN102357259A (zh) *	2011-07-28	2012-02-22	王珊珊	一种生物蛋白海绵及其制备方法
AU2012313984B2 (en)	2011-09-30	2016-02-11	Covidien Lp	Reversible stiffening of light weight mesh
FR2985170B1 (fr)	2011-12-29	2014-01-24	Sofradim Production	Prothese pour hernie inguinale
FR2985271B1 (fr)	2011-12-29	2014-01-24	Sofradim Production	Tricot a picots
WO2013142119A1 (en)	2012-03-20	2013-09-26	Trustees Of Tufts College	Silk reservoirs for drug delivery
CN104602713A (zh)	2012-04-13	2015-05-06	塔夫茨大学信托人	用于制备丝微球的方法和组合物
WO2014012101A1 (en)	2012-07-13	2014-01-16	Trustees Of Tufts College	Silk powder compaction for production of constructs with high mechanical strength and stiffness
FR2994185B1 (fr)	2012-08-02	2015-07-31	Sofradim Production	Procede de preparation d’une couche poreuse a base de chitosane
US20140056865A1 (en) *	2012-08-17	2014-02-27	Allosource	Adipose composition systems and methods
FR2995788B1 (fr)	2012-09-25	2014-09-26	Sofradim Production	Patch hemostatique et procede de preparation
FR2995779B1 (fr)	2012-09-25	2015-09-25	Sofradim Production	Prothese comprenant un treillis et un moyen de consolidation
FR2995778B1 (fr)	2012-09-25	2015-06-26	Sofradim Production	Prothese de renfort de la paroi abdominale et procede de fabrication
US10159555B2 (en)	2012-09-28	2018-12-25	Sofradim Production	Packaging for a hernia repair device
RU2015127077A (ru)	2012-12-07	2017-01-12	Антродженезис Корпорейшн	Лечение поражений полости рта при помощи внеклеточного матрикса плаценты
JP2014166217A (ja) *	2013-02-28	2014-09-11	Tokyo Institute Of Technology	コラーゲン線維無機高分子複合体及びその製造方法
NO2975611T3 (de)	2013-03-15	2018-06-09
US11376329B2 (en)	2013-03-15	2022-07-05	Trustees Of Tufts College	Low molecular weight silk compositions and stabilizing silk compositions
KR102457668B1 (ko)	2013-03-15	2022-10-21	트러스티즈 오브 터프츠 칼리지	저분자량 실크 조성물 및 안정화 실크 조성물
WO2014176458A2 (en)	2013-04-24	2014-10-30	Trustees Of Tufts College	Bioresorbable biopolymer anastomosis devices
FR3006581B1 (fr)	2013-06-07	2016-07-22	Sofradim Production	Prothese a base d’un textile pour voie laparoscopique
FR3006578B1 (fr)	2013-06-07	2015-05-29	Sofradim Production	Prothese a base d’un textile pour voie laparoscopique
US20140363418A1 (en) *	2013-06-10	2014-12-11	Molecular Biology International, Inc.	Method of producing collagen from hydrolyzed egg membrane
EP3013319A4 (de)	2013-06-24	2017-03-22	Anthrogenesis Corporation	Extrazelluläre matrixzusammensetzungskügelchen für zellkultur
CA2919374C (en)	2013-07-30	2019-12-03	Musculoskeletal Transplant Foundation	Acellular soft tissue-derived matrices and methods for preparing same
EP3000432B1 (de)	2014-09-29	2022-05-04	Sofradim Production	Textilbasierte Prothese für die Behandlung von Leistenbruch
EP3000433B1 (de)	2014-09-29	2022-09-21	Sofradim Production	Vorrichtung zur Einführung einer Prothese zur Hernie-Behandlung in einen Einschnitt und flexible textile Prothese
EP3029189B1 (de)	2014-12-05	2021-08-11	Sofradim Production	Prothetisches poröses Netz, sein Herstellungsverfahren und Hernienprothese
WO2016100721A1 (en)	2014-12-17	2016-06-23	Tufts University	Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair
EP3059255B1 (de)	2015-02-17	2020-05-13	Sofradim Production	Verfahren zur Herstellung einer Matrix auf Chitosanbasis mit faseroptischem Verstärkungselement
EP3085337B1 (de)	2015-04-24	2022-09-14	Sofradim Production	Prothese zur unterstützung einer bruststruktur
ES2676072T3 (es)	2015-06-19	2018-07-16	Sofradim Production	Prótesis sintética que comprende un tejido de punto y una película no porosa y método para formarla
CA2995233C (en)	2015-07-20	2024-01-02	Tufts University	Biodegradable silk ear tubes
US10912864B2 (en)	2015-07-24	2021-02-09	Musculoskeletal Transplant Foundation	Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en)	2015-08-19	2021-07-06	Musculoskeletal Transplant Foundation	Cartilage-derived implants and methods of making and using same
CN105316382A (zh) *	2015-12-15	2016-02-10	李国深	一种鱼骨胶原蛋白的制备方法
EP3195830B1 (de)	2016-01-25	2020-11-18	Sofradim Production	Prothese zur hernienreparatur
WO2017165281A1 (en)	2016-03-22	2017-09-28	Avicenna Nutraceutical, Llc	Hydrolyzed collagen compositions and methods of making thereof
WO2017189832A1 (en)	2016-04-29	2017-11-02	Trustees Of Tufts College	An artificial silk based innervated cornea
WO2018006037A1 (en)	2016-07-01	2018-01-04	Trustees Of Tufts College	Innervated artificial skin
WO2018026853A1 (en)	2016-08-01	2018-02-08	Trustees Of Tufts College	Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
EP3312325B1 (de)	2016-10-21	2021-09-22	Sofradim Production	Verfahren zur herstellung eines netzes mit einem daran befestigten nahtmaterial mit widerhaken und dadurch erhaltenes netz
WO2018136754A1 (en)	2017-01-20	2018-07-26	Massachusetts Institute Of Technology	Injectable polymer micro-depots for controlled local drug delivery
EP3398554B1 (de)	2017-05-02	2025-06-25	Sofradim Production	Prothese zur leistenbruch reparatur
US11419947B2 (en)	2017-10-30	2022-08-23	Massachusetts Institute Of Technology	Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
WO2019094702A1 (en)	2017-11-10	2019-05-16	Cocoon Biotech Inc.	Ocular applications of silk-based products
CN108410935A (zh) *	2018-04-09	2018-08-17	陕西科技大学	一种基于层级可控降解技术从含铬废皮渣中制备胶原集合体及胶原的方法
CN112334168B (zh)	2018-05-03	2024-10-22	科尔普兰特有限公司	真皮填充剂和其应用
US11583609B2 (en)	2018-08-08	2023-02-21	Mimedx Group, Inc.	Collagen constructs and methods of making the same
EP3653171B1 (de)	2018-11-16	2024-08-21	Sofradim Production	Implantate zur weichgewebereparatur
WO2020122198A1 (ja) *	2018-12-12	2020-06-18	学校法人近畿大学	コラーゲン固形物、コラーゲン固形物の製造方法、生体材料、および、生体外材料
CN109602896A (zh) *	2019-01-11	2019-04-12	无限极（中国）有限公司	一种胶原蛋白肽和弹性蛋白肽的组合物及其制备方法和应用
EP3975841A1 (de)	2019-05-30	2022-04-06	Massachusetts Institute of Technology	Peptid-nukleinsäurefunktionalisierte hydrogelmikronadeln zur probenahme und detektion von nukleinsäuren in interstitieller flüssigkeit
CA3142608A1 (en)	2019-06-04	2020-12-10	Cocoon Biotech Inc.	Silk-based products, formulations, and methods of use
US12064330B2 (en)	2020-04-28	2024-08-20	Covidien Lp	Implantable prothesis for minimally invasive hernia repair
WO2022221482A1 (en)	2021-04-14	2022-10-20	Cocoon Biotech Inc.	Methods of making stable silk fibroin formulations
CN113957111B (zh) *	2021-10-15	2024-01-05	海南华研胶原科技股份有限公司	一种磷酸化改性的鳕鱼胶原蛋白肽的制备方法

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2202566A (en) *	1936-02-07	1940-05-28	Koninklijke Pharma Fab Nv	Tampons and other porous articles and process for producing same
US2973302A (en) *	1955-05-18	1961-02-28	Ethicon Inc	Purification of collagen
US3157524A (en) *	1960-10-25	1964-11-17	Ethicon Inc	Preparation of collagen sponge
US3113568A (en) *	1961-12-26	1963-12-10	Eric K Erskine	Styptic bandage
GB1147072A (en) *	1965-07-09	1969-04-02	Braun Internat Gmbh B	Process for preparing a wound covering
US3520402A (en) *	1967-08-30	1970-07-14	Ethicon Inc	Purified collagen fibrils
US3529530A (en) *	1968-12-11	1970-09-22	Devro Inc	Edible water soluble collagen film
US3664844A (en) *	1970-02-10	1972-05-23	Devro Inc	Edible collagen film
US3800792A (en) *	1972-04-17	1974-04-02	Johnson & Johnson	Laminated collagen film dressing
US4488911A (en) *	1975-10-22	1984-12-18	Luck Edward E	Non-antigenic collagen and articles of manufacture
US4148664A (en) *	1976-05-10	1979-04-10	Avicon, Inc.	Preparation of fibrous collagen product having hemostatic and wound sealing properties
US4412947A (en) *	1979-09-12	1983-11-01	Seton Company	Collagen sponge
DE3037513C2 (de) *	1980-10-03	1983-05-05	Steffan, Wolfgang, 8425 Neustadt	Kollagene Wundauflage
DE3042860A1 (de) *	1980-11-13	1982-06-09	Heyl & Co Chemisch-Pharmazeutische Fabrik, 1000 Berlin	Kollagenpraeparate, verfahren zu ihrer herstellung und ihre verwendung in der human- und veterinaermedizin
US4539716A (en) *	1981-03-19	1985-09-10	Massachusetts Institute Of Technology	Fabrication of living blood vessels and glandular tissues
US4546500A (en) *	1981-05-08	1985-10-15	Massachusetts Institute Of Technology	Fabrication of living blood vessels and glandular tissues
US4350629A (en) *	1981-07-29	1982-09-21	Massachusetts Institute Of Technology	Procedures for preparing composite materials from collagen and glycosaminoglycan
JPS5826822A (ja) *	1981-08-10	1983-02-17	Kaken Pharmaceut Co Ltd	慢性腎炎治療剤
FR2516927B1 (fr) *	1981-11-26	1986-05-23	Merieux Fond	Procede de preparation industrielle de materiaux collageniques a partir de tissus placentaires humains, materiaux collageniques humains obtenus, leur application comme biomateriaux
US4424208A (en) *	1982-01-11	1984-01-03	Collagen Corporation	Collagen implant material and method for augmenting soft tissue
US4409332A (en) *	1982-01-12	1983-10-11	Jefferies Steven R	Collagen-enzyme conjugates that exhibit no inflammatory response and method for making the same
US4485097A (en) *	1982-05-26	1984-11-27	Massachusetts Institute Of Technology	Bone-equivalent and method for preparation thereof
US4837285A (en) *	1984-03-27	1989-06-06	Medimatrix	Collagen matrix beads for soft tissue repair
MX163953B (es) *	1984-03-27	1992-07-03	Univ New Jersey Med	Procedimiento para preparar una matriz biodegradable a base de colageno
US4557764A (en) *	1984-09-05	1985-12-10	Collagen Corporation	Process for preparing malleable collagen and the product thereof
US4604346A (en) *	1984-10-09	1986-08-05	Massachusetts Institute Of Technology	Skin-equivalent prepared by the use of punch biopsy
US4600533A (en) *	1984-12-24	1986-07-15	Collagen Corporation	Collagen membranes for medical use
JPH0662679B2 (ja) *	1985-06-21	1994-08-17	新田ゼラチン株式会社	組織親和性コラ−ゲンとその製法
DE3522626A1 (de) *	1985-06-25	1987-01-08	Merz & Co Gmbh & Co	Loeslicher kollagen-schwamm
US4883864A (en) *	1985-09-06	1989-11-28	Minnesota Mining And Manufacturing Company	Modified collagen compound and method of preparation
US4687518A (en) *	1985-11-06	1987-08-18	Optical Corp.	Method for manufacturing pyrogen-free collagen gels useful as contact lenses
EP0241838B1 (de) *	1986-04-07	1992-04-15	Agency Of Industrial Science And Technology	Antithrombogenisches Material
FR2601371B1 (fr) *	1986-07-11	1989-05-12	Merieux Inst	Procede de traitement du collagene en vue, notamment, d'en faciliter la reticulation et collagene obtenu par application dudit procede
IT1214505B (it) *	1987-03-12	1990-01-18	Gentili Ist Spa	Procedimento per la preparazione di collageno e prodotti cosi'ottenuto.
US4835102A (en) *	1987-03-31	1989-05-30	Eugene Bell	Tissue equivalent test systems
GB8708009D0 (en) *	1987-04-03	1987-05-07	Clayton Found Res	Injectable soft tissue augmentation materials
US4772288A (en) *	1987-06-15	1988-09-20	Borner William H	Method for producing implantable ligament and tendon prostheses and prostheses produced thereby
FR2617488B1 (fr) *	1987-07-01	1990-03-09	Tab	Procede de fabrication de structures organisees de collagene, notamment d'origine humaine, et structures organisees de collagene correspondantes
US4969912A (en) *	1988-02-18	1990-11-13	Kelman Charles D	Human collagen processing and autoimplant use
ES2060614T3 (es) *	1988-03-11	1994-12-01	Chemokol G B R Ing Buro Fur Ko	Procedimiento para la fabricacion de membranas de colageno para hemostasis, tratamiento de heridas e implantes.
GB8812993D0 (en) *	1988-06-01	1988-07-06	Natural Resources Mfg Ltd	Improvements in/relating to production of protein products
US4837379A (en) *	1988-06-02	1989-06-06	Organogenesis Inc.	Fibrin-collagen tissue equivalents and methods for preparation thereof
US4950483A (en) *	1988-06-30	1990-08-21	Collagen Corporation	Collagen wound healing matrices and process for their production
US4948540A (en) *	1988-08-01	1990-08-14	Semex Medical, Inc.	Method of preparing collagen dressing sheet material
US5064941A (en) *	1988-11-25	1991-11-12	Boston Biomedical Research Institute	Collagen extracted from collagen-containing tissue
FR2641289B1 (fr) *	1989-01-04	1991-03-15	Mitz Vladimir	Procede d'obtention de fibres de collagene de peau d'origine humaine, fibres ainsi obtenues et composition les contenant
US5106949A (en) *	1989-09-15	1992-04-21	Organogenesis, Inc.	Collagen compositions and methods for preparation thereof
US5104660A (en) *	1989-11-21	1992-04-14	Bruce A. Barber	Method of preparing an antimicrobial wound dressing
US5104957A (en) *	1990-02-28	1992-04-14	Autogenesis Technologies, Inc.	Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
US5081106A (en) *	1990-07-16	1992-01-14	The Oregon Health Sciences University	Wound dressing protocol utilizing collagen gelatin formed with iodine
US5229497A (en) *	1990-10-03	1993-07-20	Teepak, Inc.	Process for recovering collagen
JP2774695B2 (ja) *	1991-03-29	1998-07-09	コラーゲンコーポレイション	顔のしわを処置する装置および方法
US5374539A (en) *	1991-06-17	1994-12-20	Nimni; Marcel E.	Process for purifying collagen and generating bioprosthesis
US5316942A (en) *	1993-06-16	1994-05-31	Battelle Memorial Institute	Process for the production of low-cost soluble high-molecular weight collagen
US5814328A (en) *	1997-01-13	1998-09-29	Gunasekaran; Subramanian	Preparation of collagen using papain and a reducing agent

1997
- 1997-01-13 US US08/782,138 patent/US5814328A/en not_active Expired - Lifetime
1998
- 1998-01-12 EP EP98902442A patent/EP1007065B1/de not_active Expired - Lifetime
- 1998-01-12 AU AU59107/98A patent/AU740950B2/en not_active Ceased
- 1998-01-12 WO PCT/US1998/000371 patent/WO1998030225A1/en not_active Ceased
- 1998-01-12 AT AT98902442T patent/ATE264689T1/de not_active IP Right Cessation
- 1998-01-12 DE DE69823361T patent/DE69823361T2/de not_active Expired - Fee Related
- 1998-01-12 CA CA002277896A patent/CA2277896C/en not_active Expired - Fee Related
- 1998-01-12 JP JP53110798A patent/JP4025897B2/ja not_active Expired - Fee Related
- 1998-09-28 US US09/162,319 patent/US6127143A/en not_active Expired - Lifetime
2000
- 2000-10-03 US US09/677,646 patent/US6548077B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JP4025897B2 (ja)	2007-12-26
EP1007065A1 (de)	2000-06-14
US6548077B1 (en)	2003-04-15
EP1007065A4 (de)	2002-11-06
CA2277896A1 (en)	1998-07-16
AU5910798A (en)	1998-08-03
EP1007065B1 (de)	2004-04-21
AU740950B2 (en)	2001-11-15
US6127143A (en)	2000-10-03
DE69823361D1 (de)	2004-05-27
CA2277896C (en)	2003-08-26
JP2001508301A (ja)	2001-06-26
US5814328A (en)	1998-09-29
DE69823361T2 (de)	2005-05-04
WO1998030225A1 (en)	1998-07-16

Legal Events

Date	Code	Title	Description
2004-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69823361D1 (de)	2004-05-27	Herstellung von kollagen
EP1241178A1 (de)	2002-09-18	Verfahren zur herstellung von funktionellem seiden-fibroin und anwedung desselben
EE9700225A (et)	1998-02-16	Meetod diabetes mellituse raviks, kasutades KKF
ES2114924T3 (es)	1998-06-16	Procedimiento para la preparacion de fibras de colageno.
ATE314102T1 (de)	2006-01-15	Verwendung einer kollagenmembrane zur herstellung eines implantates für gesteuerte geweberegeneration
FI92718B (fi)	1994-09-15	Menetelmä tärkkelyshydrolysaatin suodatettavuuden parantamiseksi ja siihen käytettävä entsyymikoostumus
DE69730446D1 (de)	2004-09-30	Methode zur behandlung von cellulosehaltigen textilien unter verwendung eines cellulase fusionsproteins, welches zwei cellulolytische katalytische zentren enthält
MXPA02010343A (es)	2004-09-10	Matrices de colageno degradado y metodos para su preparacion.
WO1999037337A3 (en)	1999-09-30	Prostheses with associated growth factors
EA199900980A1 (ru)	2000-04-24	Улучшенные способы приготовления активированного белка с
WO1999000152A3 (de)	1999-05-27	Bioartifizielles transplantat und verfahren zu seiner herstellung
ATE265191T1 (de)	2004-05-15	Herstellungsverfahren von gewebe zur implantation
AU5761499A (en)	2000-04-10	Dermal scaffold using neutralized chitosan sponge or neutralized chitosan/collagen mixed sponge
DE69728656D1 (de)	2004-05-19	Methode zur herstellung einer flüssigen mischung
DE50001574D1 (de)	2003-04-30	Verfahren zum dehydratisieren von biologischen geweben zur herstellung von transplantat-konserven
AR008633A1 (es)	2000-02-09	Un proceso para tratar un koji de proteinas fermentado, preparado a partir de un material proteinaceo y de un carbohidrato, para la produccion de uncondimento.
HUP9901188A2 (hu)	1999-08-30	Új, meghatározott enzimkeverékek sejtkinyeréshez és sebkezeléshez
RU95119816A (ru)	1997-07-27	Способ получения биоматериала для использования в офтальмологии
BR9711104B1 (pt)	2009-05-05	processo para preparar uma composição polidispersada de sacarìdeos, composição polidispersada de sacarìdeos e produto compreendendo uma composição polidispersada de sacarìdeos.
WO2002040686A3 (en)	2004-02-12	Expression system for recombinant proteins
ATE384781T1 (de)	2008-02-15	Verfahren zur herstellung von entwickelten und unentwickelten pankreasendokrinezellen, zellpräparat und verwendung davon zur behandlung von diabetes
DE69506793D1 (de)	1999-02-04	Verfahren zur Herstellung von Naturwirkstoffe enthaltenden Spheroiden, insbesondere pflanzlichen Ursprungs, und so erhaltene Spheroide
EP1766125B1 (de)	2010-07-21	Neues und schonendes verfahren zur umwandlung des cystins von keratinhaltigen stoffen in lanthionin
BR9904948A (pt)	2000-12-12	Processo para a produção fermentativa de l-aminoácidos.
RO112643B1 (ro)	1997-11-28	Procedeu de preparare a aminoacidului-d sau a derivaţilor aminoacidului-d