ATE384781T1 - Verfahren zur herstellung von entwickelten und unentwickelten pankreasendokrinezellen, zellpräparat und verwendung davon zur behandlung von diabetes - Google Patents

Verfahren zur herstellung von entwickelten und unentwickelten pankreasendokrinezellen, zellpräparat und verwendung davon zur behandlung von diabetes

Info

Publication number
ATE384781T1
ATE384781T1 AT00201326T AT00201326T ATE384781T1 AT E384781 T1 ATE384781 T1 AT E384781T1 AT 00201326 T AT00201326 T AT 00201326T AT 00201326 T AT00201326 T AT 00201326T AT E384781 T1 ATE384781 T1 AT E384781T1
Authority
AT
Austria
Prior art keywords
endocrine cells
undeveloped
pancreatic endocrine
cell preparation
treating diabetes
Prior art date
Application number
AT00201326T
Other languages
English (en)
Inventor
Daniel Pipeleers
Original Assignee
Beta Cell N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beta Cell N V filed Critical Beta Cell N V
Application granted granted Critical
Publication of ATE384781T1 publication Critical patent/ATE384781T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT00201326T 2000-04-12 2000-04-12 Verfahren zur herstellung von entwickelten und unentwickelten pankreasendokrinezellen, zellpräparat und verwendung davon zur behandlung von diabetes ATE384781T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00201326A EP1146117B1 (de) 2000-04-12 2000-04-12 Verfahren zur Herstellung von entwickelten und unentwickelten Pankreasendokrinezellen, Zellpräparat und Verwendung davon zur Behandlung von Diabetes
CA2363971A CA2363971C (en) 2000-04-12 2001-11-26 A method for producing preparations of mature and immature pancreatic endocrine cells, the cell preparation and its use for treatment of diabetes mellitus

Publications (1)

Publication Number Publication Date
ATE384781T1 true ATE384781T1 (de) 2008-02-15

Family

ID=32070512

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00201326T ATE384781T1 (de) 2000-04-12 2000-04-12 Verfahren zur herstellung von entwickelten und unentwickelten pankreasendokrinezellen, zellpräparat und verwendung davon zur behandlung von diabetes

Country Status (8)

Country Link
US (1) US6686197B2 (de)
EP (1) EP1146117B1 (de)
AT (1) ATE384781T1 (de)
CA (1) CA2363971C (de)
DE (1) DE60037876T2 (de)
DK (1) DK1146117T3 (de)
ES (1) ES2299417T3 (de)
PT (1) PT1146117E (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030124721A1 (en) * 2001-11-09 2003-07-03 Bentley Cheatham Endocrine pancreas differentiation of adipose tissue-derived stromal cells and uses thereof
AU2003210959A1 (en) * 2002-02-12 2003-09-04 Cornell Research Foundation, Inc. Identification and high-yield isolation of human pancreatic islet progenitor and stem cells
SI1636348T1 (sl) 2003-06-20 2010-01-29 Vrije Universiteit Brussel Vub Postopek za pridobivanje beta celic iz eksokrinskih celic trebuĺ ne slinavke
EP2691084A1 (de) 2011-03-29 2014-02-05 Beta-Cell N.V. Verfahren für verkapselte therapeutische produkte und verwendungen dafür
US20150099653A1 (en) * 2011-10-28 2015-04-09 Centre National De La Recherche Scientifique Process of diagnostic, prognostic and therapeutic monitoring of solid tumors
WO2015040176A1 (en) * 2013-09-19 2015-03-26 Beta-Cell Nv Method for the treatment of diabetes mellitus
JP6749239B2 (ja) 2013-09-24 2020-09-02 ガイナー ライフ サイエンシズ，インク． 細胞インプラントのガス処理用システム
EP3541449B1 (de) 2016-11-15 2021-11-10 Giner Life Sciences, Inc. Perkutane gasdiffusionsvorrichtung zur verwendung mit einem subkutanen implantat
US11642501B2 (en) 2017-05-04 2023-05-09 Giner, Inc. Robust, implantable gas delivery device and methods, systems and devices including same
CN116121172B (zh) * 2023-03-14 2026-01-30 武汉远赞吉诺百客医学科技有限公司 一种猪胰腺单细胞悬液制备方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5050612A (en) * 1989-09-12 1991-09-24 Matsumura Kenneth N Device for computer-assisted monitoring of the body
US5858973A (en) * 1994-02-23 1999-01-12 The General Hospital Corporation Transcription factor and uses therefor
US6110743A (en) * 1995-02-10 2000-08-29 The Regents Of The University Of California Development and use of human pancreatic cell lines

Also Published As

Publication number Publication date
PT1146117E (pt) 2008-05-06
US20020177228A1 (en) 2002-11-28
DE60037876D1 (de) 2008-03-13
DK1146117T3 (da) 2008-05-26
EP1146117A1 (de) 2001-10-17
US6686197B2 (en) 2004-02-03
EP1146117B1 (de) 2008-01-23
CA2363971C (en) 2011-10-11
ES2299417T3 (es) 2008-06-01
CA2363971A1 (en) 2003-05-26
DE60037876T2 (de) 2009-01-29

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