ATE265454T1 - Phenyloxazol-1,4-diazabicyclo(3.2.2)nonanderiva e,ihre herstellung und ihre therapeutische verwendung - Google Patents

Phenyloxazol-1,4-diazabicyclo(3.2.2)nonanderiva e,ihre herstellung und ihre therapeutische verwendung

Info

Publication number: ATE265454T1
Authority: AT; Austria
Prior art keywords: nonanderiva; phenyloxazole; diazabicyclo; production; therapeutic use
Prior art date: 2000-05-31

Application number

AT01938361T

Other languages

English (en)

Inventor

Frederic Galli

Odile Leclerc

Alistair Lochead

Original Assignee

Sanofi Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-31

Filing date

2001-05-29

Publication date

2004-05-15

2001-05-29 Application filed by Sanofi Synthelabo filed Critical Sanofi Synthelabo

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE265454T1 publication Critical patent/ATE265454T1/de

Links

230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Addiction (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT01938361T 2000-05-31 2001-05-29 Phenyloxazol-1,4-diazabicyclo(3.2.2)nonanderiva e,ihre herstellung und ihre therapeutische verwendung ATE265454T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0006977A FR2809731B1 (fr)	2000-05-31	2000-05-31	Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique
PCT/FR2001/001649 WO2001092259A1 (fr)	2000-05-31	2001-05-29	Derives de 1,4-diazabicyclo[3.22]nonane-phenylisoxazole, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
ATE265454T1 true ATE265454T1 (de)	2004-05-15

Family

ID=8850828

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01938361T ATE265454T1 (de)	2000-05-31	2001-05-29	Phenyloxazol-1,4-diazabicyclo(3.2.2)nonanderiva e,ihre herstellung und ihre therapeutische verwendung

Country Status (10)

Country	Link
US (1)	US6844337B2 (de)
EP (1)	EP1289986B1 (de)
JP (1)	JP4939719B2 (de)
AR (1)	AR028648A1 (de)
AT (1)	ATE265454T1 (de)
AU (1)	AU2001264042A1 (de)
DE (1)	DE60103054T2 (de)
FR (1)	FR2809731B1 (de)
HU (1)	HUP0302115A2 (de)
WO (1)	WO2001092259A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ510287A (en)	1998-11-27	2003-05-30	Neurosearch As	8-azabicyclo[3.2.1]oct-2-ene and -octane derivatives useful as cholinergic ligands at the nicotinic acetyl choline receptor
SE0000540D0 (sv)	2000-02-18	2000-02-18	Astrazeneca Ab	New compounds
FR2832712B1 (fr) *	2001-11-23	2004-02-13	Sanofi Synthelabo	Derives de 4-(oxadiazol-3-yl)-1,4-diazabicyclo[3.2.2]nonane, leur preparation et leur application en therapeutique
SE0202465D0 (sv) *	2002-08-14	2002-08-14	Astrazeneca Ab	New compounds
SE0202430D0 (sv) *	2002-08-14	2002-08-14	Astrazeneca Ab	New Compounds
ATE353899T1 (de)	2002-09-30	2007-03-15	Neurosearch As	Neue 1,4-diazabicycloalkanderivate, deren herstellung und verwendung
PT1551835E (pt) *	2002-09-30	2007-03-30	Neurosearch As	Novos derivados de 1, 4-diazabicicloalcano, sua preparação e utilização
US7223753B2 (en)	2002-11-11	2007-05-29	Neurosearch A/S	Diazabicyclic biaryl derivatives
EP1562945B1 (de) *	2002-11-11	2006-11-15	Neurosearch A/S	1,4-dizabicyclo(3,2,2)nonane derivative, verfahren zur ihre herstellung und therapeutical verwendung
EP1599476B1 (de) *	2003-02-27	2009-10-14	Neurosearch A/S	Neue diazabicyclische arylderivate
ATE363484T1 (de) *	2003-09-26	2007-06-15	Astrazeneca Ab	Nichtamidnonane
EP1713487B1 (de) *	2004-02-04	2009-12-02	Neurosearch A/S	Diazabicyclische aryl-derivate als cholinerge rezeptor-modulatoren
DE602006019561D1 (de)	2005-02-16	2011-02-24	Neurosearch As	Diazabicyclische arylderivate und ihre verwendung als chinolinergische liganden an nikotin-acetylcholin-rezeptoren
US8173658B2 (en)	2005-12-06	2012-05-08	Neurosearch A/S	Diazabicycylic aryl derivatives and their medical use
EP2029607A1 (de)	2006-05-23	2009-03-04	NeuroSearch A/S	Neuartige 8,10-diaza-bicyclo[4.3.1]decan-derivate und ihre medizinische verwendung
ATE463497T1 (de)	2006-05-30	2010-04-15	Neurosearch As	Neues 1,4-diaza-bicycloä3.2.2ünonyl-oxadiazolyl- derivat und seine medizinische verwendung
AU2008209264B2 (en)	2007-01-22	2014-11-27	Mylan Pharmaceuticals Ulc	Pharmaceutical compositions comprising nebivolol or a nebivolol analogue
EP2389181A1 (de)	2009-01-26	2011-11-30	NeuroSearch A/S	Neue indolyl-oxadiazolyl-diazabicyclononan-derivate und ihre medizinische und diagnostische verwendung
WO2012139925A1 (en)	2011-04-15	2012-10-18	Neurosearch A/S	Labelled and un-labelled methyl-pyrrolyl-oxadiazolyl-diazabicyclononane derivatives and their medical use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IN166416B (de) *	1985-09-18	1990-05-05	Pfizer
NZ226000A (en) *	1987-09-10	1991-06-25	Merck Sharp & Dohme	Oxadiazolyl-azabicycloheptanes and pharmaceutical compositions
US5478939A (en) *	1994-07-20	1995-12-26	American Cyanamid Company	(R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives
FR2786770B1 (fr)	1998-12-04	2001-01-19	Synthelabo	Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique

2000
- 2000-05-31 FR FR0006977A patent/FR2809731B1/fr not_active Expired - Fee Related
2001
- 2001-05-29 AT AT01938361T patent/ATE265454T1/de not_active IP Right Cessation
- 2001-05-29 AU AU2001264042A patent/AU2001264042A1/en not_active Abandoned
- 2001-05-29 US US10/276,647 patent/US6844337B2/en not_active Expired - Lifetime
- 2001-05-29 EP EP01938361A patent/EP1289986B1/de not_active Expired - Lifetime
- 2001-05-29 DE DE60103054T patent/DE60103054T2/de not_active Expired - Lifetime
- 2001-05-29 HU HU0302115A patent/HUP0302115A2/hu unknown
- 2001-05-29 JP JP2002500872A patent/JP4939719B2/ja not_active Expired - Fee Related
- 2001-05-29 WO PCT/FR2001/001649 patent/WO2001092259A1/fr not_active Ceased
- 2001-05-30 AR ARP010102575A patent/AR028648A1/es not_active Application Discontinuation

Also Published As

Publication number	Publication date
US20030114461A1 (en)	2003-06-19
AR028648A1 (es)	2003-05-21
HUP0302115A2 (hu)	2003-10-28
FR2809731B1 (fr)	2002-07-19
WO2001092259A1 (fr)	2001-12-06
JP2003535089A (ja)	2003-11-25
JP4939719B2 (ja)	2012-05-30
DE60103054T2 (de)	2005-04-07
EP1289986B1 (de)	2004-04-28
US6844337B2 (en)	2005-01-18
DE60103054D1 (de)	2004-06-03
EP1289986A1 (de)	2003-03-12
FR2809731A1 (fr)	2001-12-07
AU2001264042A1 (en)	2001-12-11

Legal Events

Date	Code	Title	Description
2004-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE232865T1 (de)	2003-03-15	1,4-diazabicyclo(3.2.2)nonan-4-carboxylat und carboxamidderivate, ihre herstellung und therapeutische verwendung
DE69916828D1 (de)	2004-06-03	Pyrazoline, ihre herstellung und verwendung als medikamente
ATE424202T1 (de)	2009-03-15	Substituierte 2-thio-3,5-dicyano-4-phenyl-6- aminopyridine und ihre verwendung
ATE539062T1 (de)	2012-01-15	Bizyklishe verbindung, ihre herstellung und verwendung
DE60103394D1 (de)	2004-06-24	4-(2-phenylthiazol-5-yl)1,4-diazabicyclo[3.2.2]nonanederivate, ihre herstellung und therapeutische verwendung
DE50207849D1 (de)	2006-09-28	Substituierte 2-oxy-3,5-dicyano-4-aryl-6-aminopyridine und ihre verwendung
ATE332294T1 (de)	2006-07-15	Dihydro-1,3,5-triazin-diamin-derivate und ihre therapeutische verwendung
ATE296302T1 (de)	2005-06-15	4-(1,3,4-thiadiazolyl-2-yl)-1,4-diazabizyklo- 3.2.2 nonanderivate, ihre herstellung und ihre therapeutische verwendung
DE60038200D1 (de)	2008-04-17	ren Herstellung und Verwendung
DE10084441T1 (de)	2002-03-21	Koalinton-Pigmente, ihre Herstellung und Verwendung
DE60106151D1 (de)	2004-11-11	Additionshärtbare Silikonelastomermischungen, ihre Herstellung und Verwendung
ATE249460T1 (de)	2003-09-15	1,4-diazabicyclo(3.2.2)nonanderivate, deren herstellung und deren verwendung in heilkunde
DE69529026D1 (de)	2003-01-16	Trehalose, ihre Herstellung und ihre Verwendung
DE60107859D1 (de)	2005-01-20	Benzimidazolderivate, ihre herstellung und therapeutische verwendung
AP2004003002A0 (en)	2004-03-31	azabicyclic-substituted fused-heteroaryl compoundsfor the treatment of disease.
DE60002526D1 (de)	2003-06-12	Herstellung von Tricyclodecandicarbaldehyd, Pentacyclopentadecandicarbaldehyd und der entsprechenden Dimethanole
DE60008862D1 (de)	2004-04-15	Thienopyrimidin verbindungen, ihre herstellung und verwendung
DE69814431D1 (de)	2003-06-12	3,3-diarylpropylamine , ihre verwendung und herstellung
DE60001307D1 (de)	2003-03-06	Pyridopyranoazepinderivate, ihre herstellung und therapeutische verwendung
DE60235547D1 (de)	2010-04-15	En daraus, deren herstellung und verwendung
DE60103054D1 (de)	2004-06-03	Phenyloxazol-1,4-diazabicyclo[3.2.2]nonanderivate, ihre herstellung und ihre therapeutische verwendung
DE69901177D1 (de)	2002-05-08	Platinkomplex, dessen herstellung und dessen therapeutische verwendung
DE60100621D1 (de)	2003-09-25	4-heteroaryl-1,4-diazabicyclo 3.2.2.]nonane, ihre herstellung und ihre therapeutische anwendung
DE60103395D1 (de)	2004-06-24	1,4-diazabicyclo[3.2.2]nonanbenzoxazol-, benzothiazol- und benzoimidazolderivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung
DE60208044D1 (de)	2006-01-19	Acylaminothiazolderivate, deren herstellung und deren therapeutische verwendung