ATE265996T1 - Tri-heteroatom-substituierte und zwei kohlenstoff homologe von 15-hete und verfahren zur verwendung - Google Patents

Tri-heteroatom-substituierte und zwei kohlenstoff homologe von 15-hete und verfahren zur verwendung

Info

Publication number: ATE265996T1
Authority: AT; Austria
Prior art keywords: hete; heteroatom; tri; substituted; carbon homologue
Prior art date: 1999-11-09

Application number

AT00972335T

Other languages

English (en)

Inventor

Peter G Klimko

Mark R Hellberg

Gustav Graff

Original Assignee

Alcon Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-11-09

Filing date

2000-10-23

Publication date

2004-05-15

2000-10-23 Application filed by Alcon Inc filed Critical Alcon Inc

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE265996T1 publication Critical patent/ATE265996T1/de

Links

JSFATNQSLKRBCI-VAEKSGALSA-N 15-HETE Natural products CCCCC[C@H](O)\C=C\C=C/C\C=C/C\C=C/CCCC(O)=O JSFATNQSLKRBCI-VAEKSGALSA-N 0.000 title 1
JSFATNQSLKRBCI-UHFFFAOYSA-N 15-Hydroxyeicosatetraenoic acid Chemical compound CCCCCC(O)C=CC=CCC=CCC=CCCCC(O)=O JSFATNQSLKRBCI-UHFFFAOYSA-N 0.000 title 1
229910052799 carbon Inorganic materials 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/60—Unsaturated compounds containing ether groups, groups, groups, or groups the non-carboxylic part of the ether being unsaturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Ophthalmology & Optometry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT00972335T 1999-11-09 2000-10-23 Tri-heteroatom-substituierte und zwei kohlenstoff homologe von 15-hete und verfahren zur verwendung ATE265996T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US16436899P	1999-11-09	1999-11-09
PCT/US2000/029208 WO2001034548A2 (en)	1999-11-09	2000-10-23	3-heteroatom substituted and two carbon homologs of 15-hete and methods of use

Publications (1)

Publication Number	Publication Date
ATE265996T1 true ATE265996T1 (de)	2004-05-15

Family

ID=22594175

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00972335T ATE265996T1 (de)	1999-11-09	2000-10-23	Tri-heteroatom-substituierte und zwei kohlenstoff homologe von 15-hete und verfahren zur verwendung

Country Status (12)

Country	Link
US (2)	US6331644B1 (de)
EP (1)	EP1228027B1 (de)
JP (1)	JP2003513948A (de)
AR (1)	AR034398A1 (de)
AT (1)	ATE265996T1 (de)
AU (1)	AU776146B2 (de)
CA (1)	CA2386333A1 (de)
DE (1)	DE60010503T2 (de)
DK (1)	DK1228027T3 (de)
ES (1)	ES2215740T3 (de)
PT (1)	PT1228027E (de)
WO (1)	WO2001034548A2 (de)

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* Cited by examiner, † Cited by third party
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ATE265996T1 (de) *	1999-11-09	2004-05-15	Alcon Inc	Tri-heteroatom-substituierte und zwei kohlenstoff homologe von 15-hete und verfahren zur verwendung
JP2005505592A (ja) *	2001-10-11	2005-02-24	アルコン，インコーポレイテッド	抗炎症性ステロイドとｍｕｃ−１分泌促進薬との組み合わせによる、ドライアイを処置するための方法
US20030109508A1 (en) *	2001-10-11	2003-06-12	Alcon, Inc.	Methods for treating dry eye
US6831186B2 (en)	2001-11-06	2004-12-14	Schering Aktiengesellschft	Lipoxin A4 analogs
US6825232B2 (en) *	2002-06-14	2004-11-30	Alcon, Inc.	Use of hydroxyeicosatetraenoic acid compounds to treat ophthalmic inflammatory disorders
AU2003221707A1 (en) *	2002-06-14	2003-12-31	Alcon, Inc.	Topical use of hydroxyeicosatetraenoic acid compounds to treat psoriasis
AU2003278727A1 (en) *	2002-09-20	2004-04-08	Alcon, Inc.	Use of cytokine synthesis inhibitors for the treatment of dry eye disorders

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US4744980A (en)	1986-04-28	1988-05-17	Holly Frank J	Ophthalmic solution for treatment of dry eye syndrome
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US4921644A (en)	1988-02-29	1990-05-01	Technology Unlimited, Inc.	Mucin directed lipsome
US4906467A (en)	1988-03-24	1990-03-06	New York Medical College	Novel, long-duration treatment for glaucoma
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ZA927277B (en)	1991-10-02	1993-05-19	Boston Ocular Res	Dry eye treatment process and solution.
EP0546728A3 (en)	1991-12-13	1993-09-08	Alcon Laboratories Inc	Physiological tear compositions and methods for their preparation
CA2133966C (en)	1992-04-21	1997-09-09	David A. Sullivan	Ocular androgen therapy in sjogren's syndrome
US5290572A (en)	1992-08-06	1994-03-01	Deo Corporation	Opthalmic composition for treating dry eye
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US5723497A (en) *	1993-03-17	1998-03-03	Kao Corporation	Amine derivative and dermatologic preparation containing the same
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ATE265996T1 (de) *	1999-11-09	2004-05-15	Alcon Inc	Tri-heteroatom-substituierte und zwei kohlenstoff homologe von 15-hete und verfahren zur verwendung

2000
- 2000-10-23 AT AT00972335T patent/ATE265996T1/de not_active IP Right Cessation
- 2000-10-23 US US09/694,613 patent/US6331644B1/en not_active Expired - Fee Related
- 2000-10-23 PT PT00972335T patent/PT1228027E/pt unknown
- 2000-10-23 WO PCT/US2000/029208 patent/WO2001034548A2/en not_active Ceased
- 2000-10-23 JP JP2001536499A patent/JP2003513948A/ja not_active Withdrawn
- 2000-10-23 DE DE60010503T patent/DE60010503T2/de not_active Expired - Fee Related
- 2000-10-23 CA CA002386333A patent/CA2386333A1/en not_active Abandoned
- 2000-10-23 AU AU11011/01A patent/AU776146B2/en not_active Ceased
- 2000-10-23 DK DK00972335T patent/DK1228027T3/da active
- 2000-10-23 ES ES00972335T patent/ES2215740T3/es not_active Expired - Lifetime
- 2000-10-23 EP EP00972335A patent/EP1228027B1/de not_active Expired - Lifetime
- 2000-11-08 AR ARP000105872A patent/AR034398A1/es unknown
2001
- 2001-09-20 US US09/957,107 patent/US6437160B1/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US6331644B1 (en)	2001-12-18
EP1228027A2 (de)	2002-08-07
US20020082286A1 (en)	2002-06-27
DE60010503T2 (de)	2004-09-23
WO2001034548A2 (en)	2001-05-17
US6437160B1 (en)	2002-08-20
AU776146B2 (en)	2004-08-26
ES2215740T3 (es)	2004-10-16
DK1228027T3 (da)	2004-07-19
JP2003513948A (ja)	2003-04-15
EP1228027B1 (de)	2004-05-06
AR034398A1 (es)	2004-02-25
WO2001034548A3 (en)	2001-11-01
PT1228027E (pt)	2004-08-31
CA2386333A1 (en)	2001-05-17
DE60010503D1 (de)	2004-06-09
AU1101101A (en)	2001-06-06

Legal Events

Date

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Description

2004-11-15

UEP

Publication of translation of european patent specification

Ref document number: 1228027

Country of ref document: EP

2008-07-15

REN

Ceased due to non-payment of the annual fee

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