ATE266006T1 - 3-hydroxy-2(1h)-pyridone als chelatbildner - Google Patents
3-hydroxy-2(1h)-pyridone als chelatbildnerInfo
- Publication number
- ATE266006T1 ATE266006T1 AT95923971T AT95923971T ATE266006T1 AT E266006 T1 ATE266006 T1 AT E266006T1 AT 95923971 T AT95923971 T AT 95923971T AT 95923971 T AT95923971 T AT 95923971T AT E266006 T1 ATE266006 T1 AT E266006T1
- Authority
- AT
- Austria
- Prior art keywords
- hydroxy
- hopo
- chelating agents
- pyridinone
- disclosed
- Prior art date
Links
- 239000002738 chelating agent Substances 0.000 title abstract 6
- GGOZGYRTNQBSSA-UHFFFAOYSA-N pyridine-2,3-diol Chemical compound OC1=CC=CN=C1O GGOZGYRTNQBSSA-UHFFFAOYSA-N 0.000 title abstract 4
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 150000001408 amides Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- GQZXNSPRSGFJLY-UHFFFAOYSA-N hydroxyphosphanone Chemical group OP=O GQZXNSPRSGFJLY-UHFFFAOYSA-N 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 231100000053 low toxicity Toxicity 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 230000004962 physiological condition Effects 0.000 abstract 1
- 239000002243 precursor Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1995/007766 WO1997000245A1 (en) | 1995-06-14 | 1995-06-14 | 3-hydroxy-2(1h)-pyridinone chelating agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE266006T1 true ATE266006T1 (de) | 2004-05-15 |
Family
ID=22249334
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95923971T ATE266006T1 (de) | 1995-06-14 | 1995-06-14 | 3-hydroxy-2(1h)-pyridone als chelatbildner |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0840727B1 (de) |
| AT (1) | ATE266006T1 (de) |
| AU (1) | AU2865995A (de) |
| DE (1) | DE69533000T2 (de) |
| DK (1) | DK0840727T3 (de) |
| ES (1) | ES2221929T3 (de) |
| WO (1) | WO1997000245A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU752812B2 (en) | 1997-11-17 | 2002-10-03 | Research Corporation Technologies, Inc. | Magnetic resonance imaging agents for the detection of physiological agents |
| FI112796B (fi) * | 2000-04-14 | 2004-01-15 | Valtion Teknillinen | Menetelmä oligo-/polymeripihkahappoaimididendrimeerien valmistamiseksi ja niiden käyttö |
| US6846915B2 (en) * | 2001-08-13 | 2005-01-25 | The Regents Of The University Of California | Hydroxypyridonate and hydroxypyrimidinone chelating agents |
| US7504422B2 (en) | 2003-04-02 | 2009-03-17 | Taigen Biotechnology Co. Ltd. | Polyamine compounds |
| WO2004089360A1 (en) | 2003-04-02 | 2004-10-21 | Taigen Biotechnology | Polyamine compounds for treating chemokine receptor mediated diseases |
| DE102004062250A1 (de) * | 2004-12-23 | 2006-07-06 | Schering Ag | Konjugate von Hydroxypyridinonderivat-Metallkomplexen mit Biomolekülen und deren Verwendung zur Herstellung von Mitteln für die NMR-Diagnostik |
| US7501526B2 (en) | 2005-01-20 | 2009-03-10 | Taigen Biotechnology | Synthesis of polyamine compounds |
| CA2659251C (en) | 2006-07-10 | 2016-06-14 | The Regents Of The University Of California | Luminescent 1-hydroxy-2-pyridinone chelates of lanthanides |
| EP2104662A2 (de) | 2007-01-11 | 2009-09-30 | GE Healthcare AS | Chelatbildende mittel |
| WO2009021948A1 (en) * | 2007-08-13 | 2009-02-19 | Ge Healthcare As | Chelators, paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (mri) |
| WO2009021947A1 (en) * | 2007-08-13 | 2009-02-19 | Ge Healthcare As | Chelators, paramagnetic chelates thereof and their use as contrast agents in magnetic resonance imaging (mri) |
| WO2011025790A1 (en) | 2009-08-24 | 2011-03-03 | Lumiphore, Inc. | Macrocyclic hopo chelators |
| GB201002508D0 (en) * | 2010-02-12 | 2010-03-31 | Algeta As | Product |
| GB201019118D0 (en) | 2010-11-11 | 2010-12-29 | King S College | Conjugates and their uses in molecular imaging |
| CN102603964B (zh) * | 2012-01-15 | 2014-03-05 | 浙江工商大学 | 水溶性聚合物铁螯合剂及其制备方法和用途 |
| US11453652B2 (en) | 2013-03-15 | 2022-09-27 | Lumiphore, Inc. | Di-macrocycles |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8325494D0 (en) * | 1983-09-23 | 1983-10-26 | Hider R C | Pharmaceutical compositions |
| US4698431A (en) * | 1985-11-12 | 1987-10-06 | The United States Of America As Represented By The United States Department Of Energy | Hydroxypyridonate chelating agents |
-
1995
- 1995-06-14 AT AT95923971T patent/ATE266006T1/de not_active IP Right Cessation
- 1995-06-14 ES ES95923971T patent/ES2221929T3/es not_active Expired - Lifetime
- 1995-06-14 AU AU28659/95A patent/AU2865995A/en not_active Abandoned
- 1995-06-14 EP EP95923971A patent/EP0840727B1/de not_active Expired - Lifetime
- 1995-06-14 WO PCT/US1995/007766 patent/WO1997000245A1/en not_active Ceased
- 1995-06-14 DK DK95923971T patent/DK0840727T3/da active
- 1995-06-14 DE DE69533000T patent/DE69533000T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0840727B1 (de) | 2004-05-06 |
| ES2221929T3 (es) | 2005-01-16 |
| AU2865995A (en) | 1997-01-15 |
| DK0840727T3 (da) | 2004-08-16 |
| DE69533000D1 (de) | 2004-06-09 |
| DE69533000T2 (de) | 2005-04-21 |
| EP0840727A1 (de) | 1998-05-13 |
| WO1997000245A1 (en) | 1997-01-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0840727 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |