ATE266398T1 - Pharmazeutische zusammensetzungen enthaltend tyrphostine - Google Patents

Pharmazeutische zusammensetzungen enthaltend tyrphostine

Info

Publication number
ATE266398T1
ATE266398T1 AT97934696T AT97934696T ATE266398T1 AT E266398 T1 ATE266398 T1 AT E266398T1 AT 97934696 T AT97934696 T AT 97934696T AT 97934696 T AT97934696 T AT 97934696T AT E266398 T1 ATE266398 T1 AT E266398T1
Authority
AT
Austria
Prior art keywords
tyrphostines
pharmaceutical compositions
compositions containing
formulae
phenyl
Prior art date
Application number
AT97934696T
Other languages
English (en)
Inventor
Abraham Novogrodsky
Alexander Levitzki
Aviv Gazit
Original Assignee
Notox Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Notox Ltd filed Critical Notox Ltd
Application granted granted Critical
Publication of ATE266398T1 publication Critical patent/ATE266398T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4406—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 3, e.g. zimeldine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT97934696T 1996-08-14 1997-08-14 Pharmazeutische zusammensetzungen enthaltend tyrphostine ATE266398T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL11906996A IL119069A0 (en) 1996-08-14 1996-08-14 Pharmaceutical composition comprising tyrphostins
PCT/IL1997/000276 WO1998006391A1 (en) 1996-08-14 1997-08-14 Pharmaceutical compositions comprising tyrphostins

Publications (1)

Publication Number Publication Date
ATE266398T1 true ATE266398T1 (de) 2004-05-15

Family

ID=11069189

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97934696T ATE266398T1 (de) 1996-08-14 1997-08-14 Pharmazeutische zusammensetzungen enthaltend tyrphostine

Country Status (11)

Country Link
US (2) US6426366B1 (de)
EP (1) EP0923371B1 (de)
JP (1) JP2001504085A (de)
CN (1) CN1232392A (de)
AT (1) ATE266398T1 (de)
AU (1) AU728672B2 (de)
BR (1) BR9711160A (de)
CA (1) CA2263325A1 (de)
DE (1) DE69729104D1 (de)
IL (1) IL119069A0 (de)
WO (1) WO1998006391A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1146869A2 (de) * 1999-01-27 2001-10-24 University Of South Florida Inhibierung der stat3 signaltransduktion für krebsbehandlung
AU780844B2 (en) * 1999-10-12 2005-04-21 Temple University-Of The Commonwealth System Of Higher Education Method for protecting normal cells from cytotoxicity of chemotherapeutic agents
US20040052762A1 (en) * 2001-09-10 2004-03-18 Hua Yu Stat3 agonists and antagonists and therapeutic uses thereof
US20040197335A1 (en) * 2001-06-14 2004-10-07 Shimon Slavin Non-myeloablative tolerogenic treatment with tyrphostins
US6433018B1 (en) 2001-08-31 2002-08-13 The Research Foundation Of State University Of New York Method for reducing hypertrophy and ischemia
US7638122B2 (en) * 2003-03-07 2009-12-29 University Of South Florida Stat3 antagonists and their use as vaccines against cancer
MXPA06006460A (es) * 2003-12-11 2006-08-23 Univ Texas Compuestos para el tratamiento de enfermedades proliferativas celulares.
WO2005082415A2 (en) * 2004-02-25 2005-09-09 Dana Farber Cancer Institute, Inc. Inhibitors of insulin-like growth factor receptor-1 for inhibiting tumor cell growth
RU2456265C2 (ru) * 2006-03-31 2012-07-20 Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем Биологически доступная для перорального применения кофейная кислота, относящаяся к противоопухолевым лекарственным средствам
US20100292229A1 (en) * 2006-06-30 2010-11-18 The Board Of Regents Of The University Of Texas System Tryphostin-analogs for the treatment of cell proliferative diseases
US20110129456A1 (en) * 2008-05-05 2011-06-02 Yaolin Wang Sequential Administration of Chemotherapeutic Agents for Treatment of Cancer
AU2009268841B2 (en) 2008-07-08 2014-02-06 Board Of Regents, The University Of Texas System Novel inhibitors of proliferation and activation of signal transducer and activator of transcription (STATS)
WO2011080261A1 (en) 2009-12-28 2011-07-07 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for improved cardiomyogenic differentiation of pluripotent cells
TWI846678B (zh) 2017-11-10 2024-07-01 美國德州系統大學評議委員會 咖啡酸衍生物及其用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH484603A (de) 1966-03-21 1970-01-31 Ciba Geigy Schädlingsbekämpfungsmittel, enthaltend bestimmte Malodinitrile
US3551573A (en) 1967-11-08 1970-12-29 Monsanto Co Insecticidal composition and method containing anilinomethylene malonitriles
US3726662A (en) * 1970-01-14 1973-04-10 Monsanto Co Herbicidal anilinomethylene-malononitriles
US4151298A (en) * 1977-01-10 1979-04-24 Ciba-Geigy Corporation Anthelmintic compositions
AU632992B2 (en) 1987-12-24 1993-01-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem Pharmaceutical compositions comprising benzylidene- and cinnamylidene-malononitrile derivatives for the inhibition of proliferative processes in mammalian cells, certain such novel compounds and their preparation
RU2024514C1 (ru) 1991-10-01 1994-12-15 Иркутский институт органической химии СО РАН Комплекс 1-этилимидазола с аскорбатом цинка, повышающий устойчивость организма к действию диоксида азота и обладающий цитопротекторным и антигипоксическим действием
US5284868A (en) 1991-10-09 1994-02-08 Eli Lilly And Company Pharmaceutical compounds
US5972598A (en) * 1992-09-17 1999-10-26 Board Of Trustess Of The University Of Illinois Methods for preventing multidrug resistance in cancer cells
ATE361759T1 (de) * 1993-07-15 2007-06-15 Cancer Res Campaign Tech Verbindungen die zur herstellung von protein- tyrosin-kinase-inhibitor-prodrogen verwendet werden können
IL107736A (en) * 1993-11-24 2001-01-11 Yissum Res Dev Co Pharmaceutical composition for the prevention of septic shock and for the treatment of chronic inflammatory diseases
US5700823A (en) 1994-01-07 1997-12-23 Sugen, Inc. Treatment of platelet derived growth factor related disorders such as cancers
WO1995024190A2 (en) 1994-03-07 1995-09-14 Sugen, Inc. Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof
AU709191B2 (en) * 1995-09-11 1999-08-26 Osteoarthritis Sciences, Inc. Protein tyrosine kinase inhibitors for treating osteoarthritis

Also Published As

Publication number Publication date
IL119069A0 (en) 1996-11-14
JP2001504085A (ja) 2001-03-27
AU728672B2 (en) 2001-01-18
AU3782297A (en) 1998-03-06
US20030013748A1 (en) 2003-01-16
DE69729104D1 (de) 2004-06-17
CA2263325A1 (en) 1998-02-19
BR9711160A (pt) 2000-01-11
CN1232392A (zh) 1999-10-20
EP0923371B1 (de) 2004-05-12
WO1998006391A1 (en) 1998-02-19
EP0923371A1 (de) 1999-06-23
US6426366B1 (en) 2002-07-30

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties