MA23639A1 - Derives pyrrocarbazole, leur preparation, les compositions pharmaceutiques les contenant, leur utilisation dans le traitement des tumeurs malignes. - Google Patents

Derives pyrrocarbazole, leur preparation, les compositions pharmaceutiques les contenant, leur utilisation dans le traitement des tumeurs malignes.

Info

Publication number
MA23639A1
MA23639A1 MA23980A MA23980A MA23639A1 MA 23639 A1 MA23639 A1 MA 23639A1 MA 23980 A MA23980 A MA 23980A MA 23980 A MA23980 A MA 23980A MA 23639 A1 MA23639 A1 MA 23639A1
Authority
MA
Morocco
Prior art keywords
pyrrocarbazole
derivatives
preparation
treatment
pharmaceutical compositions
Prior art date
Application number
MA23980A
Other languages
English (en)
Inventor
Allen Broka Chris
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MA23639A1 publication Critical patent/MA23639A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
MA23980A 1994-08-04 1995-08-03 Derives pyrrocarbazole, leur preparation, les compositions pharmaceutiques les contenant, leur utilisation dans le traitement des tumeurs malignes. MA23639A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28604394A 1994-08-04 1994-08-04

Publications (1)

Publication Number Publication Date
MA23639A1 true MA23639A1 (fr) 1996-04-01

Family

ID=23096813

Family Applications (1)

Application Number Title Priority Date Filing Date
MA23980A MA23639A1 (fr) 1994-08-04 1995-08-03 Derives pyrrocarbazole, leur preparation, les compositions pharmaceutiques les contenant, leur utilisation dans le traitement des tumeurs malignes.

Country Status (29)

Country Link
US (1) US5721267A (fr)
EP (1) EP0695755B1 (fr)
JP (1) JP2672290B2 (fr)
KR (1) KR100326790B1 (fr)
CN (1) CN1051551C (fr)
AT (1) ATE172463T1 (fr)
AU (1) AU692563B2 (fr)
BR (1) BR9503536A (fr)
CA (1) CA2155148A1 (fr)
CO (1) CO4410329A1 (fr)
CZ (1) CZ288583B6 (fr)
DE (1) DE69505470T2 (fr)
DK (1) DK0695755T3 (fr)
ES (1) ES2123873T3 (fr)
FI (1) FI111258B (fr)
HU (1) HU225567B1 (fr)
IL (1) IL114785A (fr)
MA (1) MA23639A1 (fr)
MY (1) MY117092A (fr)
NO (1) NO304833B1 (fr)
NZ (1) NZ272687A (fr)
PE (1) PE34996A1 (fr)
PL (1) PL180801B1 (fr)
RU (1) RU2162089C2 (fr)
SA (1) SA95160203B1 (fr)
TR (1) TR199500954A1 (fr)
TW (1) TW403652B (fr)
UY (1) UY24010A1 (fr)
ZA (1) ZA956327B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1283203B1 (it) * 1996-03-07 1998-04-16 Ausimont Spa Composizioni estinguenti la fiamma
US6020298A (en) * 1997-03-05 2000-02-01 Ausimont S.P.A. Solvent cleaning agents including additives of the formula Rf -CFX-L containing perfluoroalkylenic units
DE19744257B4 (de) * 1997-10-07 2004-04-15 Zentaris Gmbh Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US7122679B2 (en) * 2000-05-09 2006-10-17 Cephalon, Inc. Multicyclic compounds and the use thereof
US20050070591A1 (en) * 2001-12-18 2005-03-31 Fumihiko Kanai Indole derivative
US7094798B1 (en) 2002-04-26 2006-08-22 Pfizer Inc Inhibitors of checkpoint kinases (Wee1 and Chk1)
CA2483496A1 (fr) * 2002-04-26 2003-11-06 Warner-Lambert Company Llc Inhibiteurs de checkpoint kinases (wee1 et chk1)
JP2012051804A (ja) * 2008-12-26 2012-03-15 Kyoto Univ Ｅｇ５阻害剤
RU2404983C1 (ru) * 2009-06-08 2010-11-27 Федеральное Государственное Образовательное Учреждение Высшего Профессионального Образования "Южный Федеральный Университет" СПОСОБ ПОЛУЧЕНИЯ 2-R1-6-R2-5-АРИЛ-ПИРРОЛО[3,4-с]КАРБАЗОЛ-1,3(2Н,6Н)-ДИОНОВ
ES2668775T3 (es) * 2009-06-10 2018-05-22 Chugai Seiyaku Kabushiki Kaisha Compuestos tetracíclicos
MX355836B (es) 2010-08-20 2018-05-02 Chugai Pharmaceutical Co Ltd Composicion que comprende compuestos tetraciclicos.
US10668075B2 (en) 2012-09-25 2020-06-02 Chugai Seiyaku Kabushiki Kaisha RET inhibitor
KR101577098B1 (ko) 2012-11-20 2015-12-14 주식회사 두산 유기 화합물 및 이를 포함하는 유기 전계 발광 소자
WO2015163448A1 (fr) 2014-04-25 2015-10-29 中外製薬株式会社 Préparation contenant un composé tétracyclique à haute dose
EP3135671B1 (fr) 2014-04-25 2019-09-18 Chugai Seiyaku Kabushiki Kaisha Nouveau cristal de composé tétracyclique
TWI831347B (zh) 2014-08-08 2024-02-01 日商中外製藥股份有限公司 包含４環性化合物的非晶質體之固體分散體及製劑
JP6741596B2 (ja) 2015-01-16 2020-08-19 中外製薬株式会社 併用医薬
CN112384223B (zh) 2018-06-29 2024-08-27 中外制药株式会社 含有难溶性碱性药剂的药物组合物
WO2020050241A1 (fr) 2018-09-04 2020-03-12 中外製薬株式会社 Procédé de production de composé tétracyclique
KR102509614B1 (ko) * 2022-08-09 2023-03-13 김학수 부직포 패널 제조방법 및 제조장치

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611762D0 (en) * 1986-05-14 1986-06-25 Wellcome Found Polycyclic biocidal compounds
US4785085A (en) * 1986-11-21 1988-11-15 Bristol-Myers Company Rebeccamycin analogs
SK75289A3 (en) * 1988-02-10 1998-05-06 Hoffmann La Roche Substituted pyrroles, their use for producing a drug, and the drug on their base
DE3833008A1 (de) * 1988-09-29 1990-04-05 Goedecke Ag Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
MC2096A1 (fr) * 1989-02-23 1991-02-15 Hoffmann La Roche Pyrroles substitues
GB2239013B (en) * 1989-11-01 1993-06-02 Toyama Chemical Co Ltd Novel isoindole derivatives and salts thereof,processes for producing the same and antitumor agent comprising the same
DE4005969A1 (de) * 1990-02-26 1991-08-29 Boehringer Mannheim Gmbh Neue trisubstituierte pyrrole, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
DE4217964A1 (de) * 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
AU678435B2 (en) * 1993-05-10 1997-05-29 F. Hoffmann-La Roche Ag Substituted pyrroles
EP0699204B1 (fr) * 1993-05-28 1998-04-15 Cephalon, Inc. Utilisation de derives de l'indolocarbozole pour traiter une affection de la prostate

Also Published As

Publication number Publication date
KR100326790B1 (ko) 2002-07-27
DK0695755T3 (da) 1999-06-28
AU692563B2 (en) 1998-06-11
TW403652B (en) 2000-09-01
IL114785A (en) 1998-06-15
PE34996A1 (es) 1996-10-01
DE69505470T2 (de) 1999-05-12
CA2155148A1 (fr) 1996-02-05
MY117092A (en) 2004-05-31
FI953710A0 (fi) 1995-08-03
PL180801B1 (pl) 2001-04-30
NO953052L (no) 1996-02-05
ATE172463T1 (de) 1998-11-15
SA95160203B1 (ar) 2005-07-31
CO4410329A1 (es) 1997-01-09
NO953052D0 (no) 1995-08-03
NO304833B1 (no) 1999-02-22
ES2123873T3 (es) 1999-01-16
AU2722095A (en) 1996-02-15
HUT73437A (en) 1996-07-29
UY24010A1 (es) 2000-12-29
HU9502270D0 (en) 1995-09-28
ZA956327B (en) 1996-02-04
EP0695755B1 (fr) 1998-10-21
US5721267A (en) 1998-02-24
CZ288583B6 (cs) 2001-07-11
EP0695755A1 (fr) 1996-02-07
RU2162089C2 (ru) 2001-01-20
CN1051551C (zh) 2000-04-19
NZ272687A (en) 1997-04-24
HU225567B1 (en) 2007-03-28
BR9503536A (pt) 1996-06-04
KR960007592A (ko) 1996-03-22
IL114785A0 (en) 1995-11-27
CZ199795A3 (en) 1996-02-14
HK1012341A1 (en) 1999-07-30
FI111258B (fi) 2003-06-30
JPH0859666A (ja) 1996-03-05
CN1123280A (zh) 1996-05-29
DE69505470D1 (de) 1998-11-26
FI953710L (fi) 1996-02-05
PL309874A1 (en) 1996-02-05
TR199500954A1 (tr) 1996-10-21
JP2672290B2 (ja) 1997-11-05

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