ATE266418T1 - Malignitätsunterdrückung durch verwendung von ribonucleotid reductase r1 - Google Patents

Malignitätsunterdrückung durch verwendung von ribonucleotid reductase r1

Info

Publication number
ATE266418T1
ATE266418T1 AT98910553T AT98910553T ATE266418T1 AT E266418 T1 ATE266418 T1 AT E266418T1 AT 98910553 T AT98910553 T AT 98910553T AT 98910553 T AT98910553 T AT 98910553T AT E266418 T1 ATE266418 T1 AT E266418T1
Authority
AT
Austria
Prior art keywords
ribonucleotide reductase
mammal
cell
provides
malignance
Prior art date
Application number
AT98910553T
Other languages
English (en)
Inventor
Jim A Wright
Aiping H Young
Original Assignee
Genesense Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genesense Technologies Inc filed Critical Genesense Technologies Inc
Application granted granted Critical
Publication of ATE266418T1 publication Critical patent/ATE266418T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44Oxidoreductases (1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y117/00Oxidoreductases acting on CH or CH2 groups (1.17)
    • C12Y117/04Oxidoreductases acting on CH or CH2 groups (1.17) with a disulfide as acceptor (1.17.3)
    • C12Y117/04001Ribonucleoside-diphosphate reductase (1.17.4.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
AT98910553T 1997-03-19 1998-03-18 Malignitätsunterdrückung durch verwendung von ribonucleotid reductase r1 ATE266418T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4083797P 1997-03-19 1997-03-19
US6066997P 1997-10-02 1997-10-02
PCT/CA1998/000242 WO1998041231A1 (en) 1997-03-19 1998-03-18 Suppression of malignancy utilizing ribonucleotide reductase r1

Publications (1)

Publication Number Publication Date
ATE266418T1 true ATE266418T1 (de) 2004-05-15

Family

ID=26717500

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98910553T ATE266418T1 (de) 1997-03-19 1998-03-18 Malignitätsunterdrückung durch verwendung von ribonucleotid reductase r1

Country Status (10)

Country Link
US (2) US6472376B2 (de)
EP (1) EP0971731B1 (de)
JP (1) JP2002501486A (de)
CN (1) CN1256632A (de)
AT (1) ATE266418T1 (de)
AU (1) AU742176B2 (de)
CA (1) CA2301874C (de)
DE (1) DE69823813T2 (de)
ES (1) ES2222577T3 (de)
WO (1) WO1998041231A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1329146A (zh) * 2000-06-21 2002-01-02 上海博德基因开发有限公司 一种新的多肽——核苷酸还原酶10.49和编码这种多肽的多核苷酸
WO2008051527A2 (en) * 2006-10-23 2008-05-02 Psivida, Inc. Sustained release of agents for localized pain management

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3082204B2 (ja) * 1988-09-01 2000-08-28 ホワイトヘッド・インスティチュート・フォー・バイオメディカル・リサーチ 両栄養性および環境栄養性宿主域を持つ組換え体レトロウイルス
US5518913A (en) * 1991-10-10 1996-05-21 National Research Council Of Canada High level recombinant protein production using conditional helper-free adenovirus vector
US5643599A (en) * 1995-06-07 1997-07-01 President And Fellows Of Harvard College Intracellular delivery of macromolecules
AU3249897A (en) * 1996-07-01 1998-01-21 Jim A. Wright Oligonucleotides from the untranslated regions of housekeeping genes and methods of using same to modulate cell growth
CN1189562C (zh) 1996-08-02 2005-02-16 吉倪塞思技术公司 针对核糖核苷酸还原酶r1和r2组分的抗肿瘤反义序列
EP1100533A2 (de) * 1998-07-31 2001-05-23 Centre De Recherche Du Centre Hospitalier De L'Universite De Montreal Anti apoptotische zusammensetzungen die die r1 untereinheit von herpes simplex virus ribonukleotide reduktase oder n-endgruppe enthalten und deren verwendungen

Also Published As

Publication number Publication date
CA2301874A1 (en) 1998-09-24
US6472376B2 (en) 2002-10-29
WO1998041231A1 (en) 1998-09-24
EP0971731A1 (de) 2000-01-19
DE69823813T2 (de) 2005-06-30
EP0971731B1 (de) 2004-05-12
JP2002501486A (ja) 2002-01-15
AU6492298A (en) 1998-10-12
US20030087866A1 (en) 2003-05-08
ES2222577T3 (es) 2005-02-01
CA2301874C (en) 2009-02-17
CN1256632A (zh) 2000-06-14
US20020004488A1 (en) 2002-01-10
AU742176B2 (en) 2001-12-20
DE69823813D1 (de) 2004-06-17
HK1024640A1 (en) 2000-10-20

Similar Documents

Publication Publication Date Title
MX9800719A (es) Proteinas de transporte y sus usos.
DE59711812D1 (de) Rekombinante collagenase typ i aus clostridium histolyticum und ihre verwendung zur isolierung von zellen und zellverbänden
WO2023230578A9 (en) Compositions and methods for modulating circulating factors
DE69937347D1 (de) Regulierung der hämatopoietischen stammzelldifferenzierung durch verwendung von menschlichen mesenchymalen stammzellen
ATE335078T1 (de) Überexpression von säugetier- und virusproteinen
CA2323086A1 (en) Regulation of endogenous gene expression in cells using zinc finger proteins
AU1750297A (en) Humanized green fluorescent protein genes and methods
DE69734930D1 (de) Adenovirales fiberprotein mit einem kurzen schaft und seine verwendung
ATE305972T1 (de) Herstellungsmethode von glycerin mittels rekombinanten organismen
DE69738586D1 (de) Hohe expressionsrate von proteinen
DE69637545D1 (de) Chimärisches , adenovirales faserprotein und verfahren zu dessen verwendung
ATE76878T1 (de) Solubilisierung von protein-aggregaten.
CA2285667A1 (en) Viral vectors having chimeric envelope proteins containing the igg-binding domain of protein a
BR9407512A (pt) Sequência de ácidos nucléicos vírus recombinante defectivo vetor notadamente virale composição farmaceutica e utilização de uma sequencia de ácidos nucléicos
DE69834565D1 (de) Schnell erzeugung von stabilen säugertier-zellinien mit gewinnung eines hohen gehalts von recombinanten proteine
WO1999025878A3 (en) Methods for modulating and identifying cellular senescence
ATE294856T1 (de) Lunasin peptide
DE69631972D1 (de) Proliferationsinhibitor von endothellzellen und dessen verwendung
CA2260365A1 (en) Differentiation-suppressive polypeptide
WO1997039721A3 (en) Methods and compositions for regulating t cell subsets by modulating transcription factor activity
ATE380873T1 (de) Prenylcystein carboxyl methyl-transferase, dns, welche für selbige kodiert, und ein verfahren zur suche nach hemmstoffen
DE69634563D1 (de) Verbesserte verfahren zur transfektion der t-zellen
EP1702071A4 (de) Transaktivierungssystem für säugerzellen
TR200000288T2 (tr) İnsülin C-peptidin rekombinan ekspresyonu.
ATE266418T1 (de) Malignitätsunterdrückung durch verwendung von ribonucleotid reductase r1

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties