ATE26709T1 - Sparsomycin(sc-rs)-derivate; pharmazeutische zusammensetzung mit antitumorwirkung. - Google Patents

Sparsomycin(sc-rs)-derivate; pharmazeutische zusammensetzung mit antitumorwirkung.

Info

Publication number: ATE26709T1
Authority: AT; Austria
Prior art keywords: sparsomycin; derivatives; antitumors; activity; pharmaceutical composition
Prior art date: 1982-11-01

Application number

AT83201556T

Other languages

English (en)

Inventor

H C J Ottenheijm

R M J Cancer Ctr Inst Liskamp

Street

Original Assignee

Stichting Katholieke Univ

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-11-01

Filing date

1983-10-31

Publication date

1987-05-15

1983-10-31 Application filed by Stichting Katholieke Univ filed Critical Stichting Katholieke Univ

1987-05-15 Application granted granted Critical

1987-05-15 Publication of ATE26709T1 publication Critical patent/ATE26709T1/de

Links

XKLZIVIOZDNKEQ-CLQLPEFOSA-N sparsomycin Chemical compound CSC[S@](=O)C[C@H](CO)NC(=O)\C=C\C1=C(C)NC(=O)NC1=O XKLZIVIOZDNKEQ-CLQLPEFOSA-N 0.000 title abstract 5
229950009641 sparsomycin Drugs 0.000 title abstract 3
XKLZIVIOZDNKEQ-UHFFFAOYSA-N sparsomycin Natural products CSCS(=O)CC(CO)NC(=O)C=CC1=C(C)NC(=O)NC1=O XKLZIVIOZDNKEQ-UHFFFAOYSA-N 0.000 title abstract 3
239000008194 pharmaceutical composition Substances 0.000 title 1
125000006755 (C2-C20) alkyl group Chemical group 0.000 abstract 1
125000002877 alkyl aryl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
230000001085 cytostatic effect Effects 0.000 abstract 1
-1 n-octyl Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/905—Streptomyces sparogenes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

AT83201556T 1982-11-01 1983-10-31 Sparsomycin(sc-rs)-derivate; pharmazeutische zusammensetzung mit antitumorwirkung. ATE26709T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL8204224		1982-11-01
EP83201556A EP0108455B1 (de)	1982-11-01	1983-10-31	Sparsomycin(Sc-Rs)-Derivate; pharmazeutische Zusammensetzung mit Antitumorwirkung

Publications (1)

Publication Number	Publication Date
ATE26709T1 true ATE26709T1 (de)	1987-05-15

Family

ID=19840504

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT83201556T ATE26709T1 (de)	1982-11-01	1983-10-31	Sparsomycin(sc-rs)-derivate; pharmazeutische zusammensetzung mit antitumorwirkung.

Country Status (9)

Country	Link
US (1)	US4581360A (de)
EP (1)	EP0108455B1 (de)
JP (1)	JPS5998069A (de)
AT (1)	ATE26709T1 (de)
AU (1)	AU565425B2 (de)
CA (1)	CA1248105A (de)
DE (1)	DE3371075D1 (de)
DK (1)	DK159310C (de)
IE (1)	IE56130B1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4595687A (en) *	1984-07-18	1986-06-17	Merrell Dow Pharmaceuticals Inc.	Sparsomycin derivatives
CH660305A5 (de) *	1984-10-05	1987-04-15	Schering Spa	Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
US4820712A (en) *	1986-08-27	1989-04-11	Stichting Katholieke Universiteit	Sparsomycin (SC-RS) compounds having antitumor activity, a process for their preparation and pharmaceutical compositions containing sparsomycin (SC-RS) compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0048532A3 (de) *	1981-11-20	1983-04-27	Stichting Research en Techniek van de Katholieke Universiteit	Sultine, Verfahren zu ihrer Herstellung, Verfahren zur Herstellung von Sulfoxiden, Verfahren zur Herstellung von Sparsomycin und verwandten Verbindungen

1983
- 1983-10-21 AU AU20443/83A patent/AU565425B2/en not_active Ceased
- 1983-10-25 IE IE2491/83A patent/IE56130B1/en not_active IP Right Cessation
- 1983-10-31 AT AT83201556T patent/ATE26709T1/de not_active IP Right Cessation
- 1983-10-31 EP EP83201556A patent/EP0108455B1/de not_active Expired
- 1983-10-31 CA CA000440062A patent/CA1248105A/en not_active Expired
- 1983-10-31 DK DK496783A patent/DK159310C/da not_active IP Right Cessation
- 1983-10-31 DE DE8383201556T patent/DE3371075D1/de not_active Expired
- 1983-11-01 JP JP58205712A patent/JPS5998069A/ja active Pending
- 1983-12-09 US US06/546,845 patent/US4581360A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DK496783A (da)	1984-05-02
EP0108455A1 (de)	1984-05-16
AU2044383A (en)	1984-05-10
DK496783D0 (da)	1983-10-31
DE3371075D1 (en)	1987-05-27
US4581360A (en)	1986-04-08
CA1248105A (en)	1989-01-03
IE832491L (en)	1984-05-01
DK159310C (da)	1991-02-25
IE56130B1 (en)	1991-04-24
DK159310B (da)	1990-10-01
JPS5998069A (ja)	1984-06-06
AU565425B2 (en)	1987-09-17
EP0108455B1 (de)	1987-04-22

Legal Events

Date	Code	Title	Description
1987-09-15	UEP	Publication of translation of european patent specification
1993-07-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DE3586545D1 (de)	1992-09-24	Erhoehte schmerzlosigkeit bewirkende pharmazeutische zusammensetzungen.
FI873113L (fi)	1988-01-16	Tvaettmedelskomposition.
FI863362A7 (fi)	1987-10-16	Farmaseuttinen koostumus.
DE3863963D1 (de)	1991-09-05	Pharmazeutische zusammensetzungen.
FI905718L (fi)	1991-05-21	Transdermalt medel.
NL190553C (nl)	1994-04-18	Gesubstitueerde (2-imidazolin-2-yl)aminopirimidinen, alsmede farmaceutisch preparaat met antihypertensieve werking, dat een of meer van deze verbindingen bevat.
DE3887800D1 (de)	1994-03-24	Substituierte Guanidine.
DE58902185D1 (de)	1992-10-08	Ampulle.
DE3785281D1 (de)	1993-05-13	Grundierungszusammensetzungen.
FI885026L (fi)	1988-11-01	Haorvaordsmedel.
FI884778A7 (fi)	1989-04-21	Kalanderdrift.
DE3879811D1 (de)	1993-05-06	Pharmazeutische zusammensetzung und ihre verwendung.
IT8721410A0 (it)	1987-07-23	Composizione farmaceutica idrosolubile contenente n acetilcisteina.
FI872733A0 (fi)	1987-06-18	Farmaceutiska kompositioner.
DE3575072D1 (de)	1990-02-08	Pharmazeutische zusammensetzungen von mikrobenerzeugtem interleukin-2.
FI872313A0 (fi)	1987-05-25	Farmaceutiska kompositioner.
FI883673A0 (fi)	1988-08-05	Farmaceutiska kompositioner.
DE68914726D1 (de)	1994-05-26	Thiokarbonsäure oder ihre Derivate enthaltende Klebzusammensetzung.
IT8820388A0 (it)	1988-04-29	Composizione oftalmologica.
ES2019305B3 (es)	1991-06-16	Pelicula o lampara para ahuyentar insectos.
NO873600D0 (no)	1987-08-26	Stabilisator for foringsroer.
ATE26709T1 (de)	1987-05-15	Sparsomycin(sc-rs)-derivate; pharmazeutische zusammensetzung mit antitumorwirkung.
FI893279A0 (fi)	1989-07-05	Antivirusmedel samt kompositioner innehaollande desamma.
NO163364C (no)	1990-05-16	Vertikal arkstabler.
AT364678B (de)	1981-11-10	Lagerbestaendige, schnell wirkende tablette zur bekaempfung von ueberwiegend in unterirdischen bauen lebenden wirbeltieren