DK496783A - Sparsomycin (sc-rs) derivat, farmaceutisk sammensaetning med anti-tumor effekt - Google Patents

Sparsomycin (sc-rs) derivat, farmaceutisk sammensaetning med anti-tumor effekt Download PDF

Info

Publication number: DK496783A
Authority: DK; Denmark
Prior art keywords: sparsomycin; derivative; pharmaceutical composition; tumor effect; derivatives
Prior art date: 1982-11-01

Application number

DK496783A

Other languages

English (en)

Other versions

DK159310C (da

DK159310B (da

DK496783D0 (da

Inventor

Henricus Carl Josep Ottenheijm

Robertus Matthias Jose Liskamp

Original Assignee

Stichting Katholieke Univ

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-11-01

Filing date

1983-10-31

Publication date

1984-05-02

1983-10-31 Application filed by Stichting Katholieke Univ filed Critical Stichting Katholieke Univ

1983-10-31 Publication of DK496783D0 publication Critical patent/DK496783D0/da

1984-05-02 Publication of DK496783A publication Critical patent/DK496783A/da

1990-10-01 Publication of DK159310B publication Critical patent/DK159310B/da

1991-02-25 Application granted granted Critical

1991-02-25 Publication of DK159310C publication Critical patent/DK159310C/da

Links

XKLZIVIOZDNKEQ-CLQLPEFOSA-N sparsomycin Chemical compound CSC[S@](=O)C[C@H](CO)NC(=O)\C=C\C1=C(C)NC(=O)NC1=O XKLZIVIOZDNKEQ-CLQLPEFOSA-N 0.000 title abstract 5
229950009641 sparsomycin Drugs 0.000 title abstract 3
XKLZIVIOZDNKEQ-UHFFFAOYSA-N sparsomycin Natural products CSCS(=O)CC(CO)NC(=O)C=CC1=C(C)NC(=O)NC1=O XKLZIVIOZDNKEQ-UHFFFAOYSA-N 0.000 title abstract 3
230000000259 anti-tumor effect Effects 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000006755 (C2-C20) alkyl group Chemical group 0.000 abstract 1
125000002877 alkyl aryl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
230000001085 cytostatic effect Effects 0.000 abstract 1
-1 n-octyl Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/905—Streptomyces sparogenes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

DK496783A 1982-11-01 1983-10-31 Analogifremgangsmaade til fremstilling af sparsomycin-(sc-rs)-derivater DK159310C (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL8204224		1982-11-01

Publications (4)

Publication Number	Publication Date
DK496783D0 DK496783D0 (da)	1983-10-31
DK496783A true DK496783A (da)	1984-05-02
DK159310B DK159310B (da)	1990-10-01
DK159310C DK159310C (da)	1991-02-25

Family

ID=19840504

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK496783A DK159310C (da)	1982-11-01	1983-10-31	Analogifremgangsmaade til fremstilling af sparsomycin-(sc-rs)-derivater

Country Status (9)

Country	Link
US (1)	US4581360A (da)
EP (1)	EP0108455B1 (da)
JP (1)	JPS5998069A (da)
AT (1)	ATE26709T1 (da)
AU (1)	AU565425B2 (da)
CA (1)	CA1248105A (da)
DE (1)	DE3371075D1 (da)
DK (1)	DK159310C (da)
IE (1)	IE56130B1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4595687A (en) *	1984-07-18	1986-06-17	Merrell Dow Pharmaceuticals Inc.	Sparsomycin derivatives
CH660305A5 (de) *	1984-10-05	1987-04-15	Schering Spa	Wasserloesliche pharmazeutische zusammensetzungen auf der basis von salzen der (-)cis-1,2-epoxypropylphosphonsaeure mit aminosaeuren.
US4820712A (en) *	1986-08-27	1989-04-11	Stichting Katholieke Universiteit	Sparsomycin (SC-RS) compounds having antitumor activity, a process for their preparation and pharmaceutical compositions containing sparsomycin (SC-RS) compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0048532A3 (en) *	1981-11-20	1983-04-27	Stichting Research en Techniek van de Katholieke Universiteit	Sultines; a process for producing these; a process for producing sulfoxides; a process for producing sparsomycin and related compounds

1983
- 1983-10-21 AU AU20443/83A patent/AU565425B2/en not_active Ceased
- 1983-10-25 IE IE2491/83A patent/IE56130B1/en not_active IP Right Cessation
- 1983-10-31 CA CA000440062A patent/CA1248105A/en not_active Expired
- 1983-10-31 DE DE8383201556T patent/DE3371075D1/de not_active Expired
- 1983-10-31 EP EP83201556A patent/EP0108455B1/en not_active Expired
- 1983-10-31 DK DK496783A patent/DK159310C/da not_active IP Right Cessation
- 1983-10-31 AT AT83201556T patent/ATE26709T1/de not_active IP Right Cessation
- 1983-11-01 JP JP58205712A patent/JPS5998069A/ja active Pending
- 1983-12-09 US US06/546,845 patent/US4581360A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ATE26709T1 (de)	1987-05-15
US4581360A (en)	1986-04-08
AU2044383A (en)	1984-05-10
DK159310C (da)	1991-02-25
IE56130B1 (en)	1991-04-24
IE832491L (en)	1984-05-01
JPS5998069A (ja)	1984-06-06
DE3371075D1 (en)	1987-05-27
AU565425B2 (en)	1987-09-17
EP0108455B1 (en)	1987-04-22
DK159310B (da)	1990-10-01
CA1248105A (en)	1989-01-03
DK496783D0 (da)	1983-10-31
EP0108455A1 (en)	1984-05-16

Legal Events

Date	Code	Title	Description
1993-06-28	PBP	Patent lapsed

Publication	Publication Date	Title
FI882456L (fi)	1988-11-29	Human proapolipoprotein a-i expression.
NO885283D0 (no)	1988-11-25	Foringsinnsats for brennkammer.
DE3777251D1 (de)	1992-04-16	2-phenoxypyrimidin-derivat und herbizide zusammensetzungen.
FI863362A7 (fi)	1987-10-16	Farmaseuttinen koostumus.
FI884298L (fi)	1989-03-19	Absorberande produkt med hydrofobiskt sugskikt.
FI873812A7 (fi)	1989-03-03	Foerfarande och anordning i en torkningsgrupp med enkel vira foer pappersmaskin.
FI884312L (fi)	1988-09-20	Faestelement foersett med en underlaeggsbricka med stor yta.
FI883402L (fi)	1989-01-21	Esternitratderivat.
FI872733A0 (fi)	1987-06-18	Farmaceutiska kompositioner.
FI885256A0 (fi)	1988-11-14	Kalander med foerskjutbara lagerdelar.
FI872313A0 (fi)	1987-05-25	Farmaceutiska kompositioner.
FI883097A7 (fi)	1988-12-31	Tioureaderivat.
IT8820388A0 (it)	1988-04-29	Composizione oftalmologica.
IT1207759B (it)	1989-06-01	Cassetto per mobili.
DK496783D0 (da)	1983-10-31	Sparsomycin (sc-rs) derivat, farmaceutisk sammensaetning med antitumor effekt
ES2022896B3 (es)	1991-12-16	Derivados de azol utiles para el control de enfermedades vegetales.
IT1217315B (it)	1990-03-22	Composti triazinici derivati dalla 2,2,6,6-tetrametilpiperidina
MX9202507A (es)	1992-11-01	Composicion farmaceutica para el tratamiento de esofagitis de reflujo.
DE3885482D1 (de)	1993-12-16	Pyridyloxy-Derivate.
IT8722560A0 (it)	1987-11-09	Azolilderivati fungicidi.
FI885360A7 (fi)	1989-05-24	Prolaekemedel med antitumoereffekt.
IT8619481A0 (it)	1986-02-20	Derivati eterociclici.
NO883721D0 (no)	1988-08-19	Tennsats for eksplosiver.
IT8706732V0 (it)	1987-12-07	Cassetto per mobili.
IT8619486A0 (it)	1986-02-20	Derivati eterociclici.