ATE267610T1 - Glykosylierte igg antikörper - Google Patents

Glykosylierte igg antikörper

Info

Publication number
ATE267610T1
ATE267610T1 AT97916787T AT97916787T ATE267610T1 AT E267610 T1 ATE267610 T1 AT E267610T1 AT 97916787 T AT97916787 T AT 97916787T AT 97916787 T AT97916787 T AT 97916787T AT E267610 T1 ATE267610 T1 AT E267610T1
Authority
AT
Austria
Prior art keywords
antibody
fragment
igg antibodies
glycosylated
glycosylated igg
Prior art date
Application number
AT97916787T
Other languages
English (en)
Inventor
Shui-On Leung
Hans Hansen
Zhengxing Qu
Original Assignee
Immunomedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunomedics Inc filed Critical Immunomedics Inc
Application granted granted Critical
Publication of ATE267610T1 publication Critical patent/ATE267610T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/40Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41Glycosylation, sialylation, or fucosylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54F(ab')2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT97916787T 1996-03-20 1997-03-19 Glykosylierte igg antikörper ATE267610T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1370996P 1996-03-20 1996-03-20
PCT/US1997/004196 WO1997034632A1 (en) 1996-03-20 1997-03-19 Glycosylated humanized b-cell specific antibodies

Publications (1)

Publication Number Publication Date
ATE267610T1 true ATE267610T1 (de) 2004-06-15

Family

ID=21761323

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97916787T ATE267610T1 (de) 1996-03-20 1997-03-19 Glykosylierte igg antikörper

Country Status (8)

Country Link
US (3) US6254868B1 (de)
EP (1) EP0888125B1 (de)
JP (1) JP3904238B2 (de)
AT (1) ATE267610T1 (de)
AU (1) AU705063B2 (de)
CA (1) CA2249320C (de)
DE (1) DE69729283T2 (de)
WO (1) WO1997034632A1 (de)

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JP3904238B2 (ja) 2007-04-11
US6254868B1 (en) 2001-07-03
US20040258682A1 (en) 2004-12-23
AU705063B2 (en) 1999-05-13
DE69729283D1 (de) 2004-07-01
CA2249320C (en) 2008-12-23
CA2249320A1 (en) 1997-09-25
EP0888125B1 (de) 2004-05-26
EP0888125A4 (de) 2001-04-25
EP0888125A1 (de) 1999-01-07
JP2000507818A (ja) 2000-06-27
WO1997034632A1 (en) 1997-09-25
DE69729283T2 (de) 2005-05-25
US20030035800A1 (en) 2003-02-20
AU2531897A (en) 1997-10-10

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