ATE267831T1 - Kristalle von cephemderivaten und verfahren zu ihrer herstellung - Google Patents

Kristalle von cephemderivaten und verfahren zu ihrer herstellung

Info

Publication number: ATE267831T1
Authority: AT; Austria
Prior art keywords: crystals; production; cephem derivatives; cephem; derivatives
Prior art date: 1999-09-30

Application number

AT00962912T

Other languages

English (en)

Inventor

Takashi Moriyoshi

Yasuhiro Uosaki

Yutaka Kameyama

Daisuke Suzuki

Yoshiko Seo

Original Assignee

Otsuka Kagaku Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-09-30

Filing date

2000-09-28

Publication date

2004-06-15

2000-09-28 Application filed by Otsuka Kagaku Kk filed Critical Otsuka Kagaku Kk

2004-06-15 Application granted granted Critical

2004-06-15 Publication of ATE267831T1 publication Critical patent/ATE267831T1/de

Links

239000013078 crystal Substances 0.000 title abstract 2
150000001782 cephems Chemical class 0.000 title 1
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
FZEVMBJWXHDLDB-ZCFIWIBFSA-N (6r)-5-thia-1-azabicyclo[4.2.0]oct-2-en-8-one Chemical class S1CC=CN2C(=O)C[C@H]21 FZEVMBJWXHDLDB-ZCFIWIBFSA-N 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
-1 p-methoxybenzyl ester Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)

AT00962912T 1999-09-30 2000-09-28 Kristalle von cephemderivaten und verfahren zu ihrer herstellung ATE267831T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP27853599		1999-09-30
JP27908099		1999-09-30
PCT/JP2000/006693 WO2001023393A1 (en)	1999-09-30	2000-09-28	3-cephem derivative crystal and method for preparing the same

Publications (1)

Publication Number	Publication Date
ATE267831T1 true ATE267831T1 (de)	2004-06-15

Family

ID=26552911

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT00962912T ATE267831T1 (de)	1999-09-30	2000-09-28	Kristalle von cephemderivaten und verfahren zu ihrer herstellung
AT04012048T ATE335747T1 (de)	1999-09-30	2000-09-28	Kristallines 3-cephem derivat

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT04012048T ATE335747T1 (de)	1999-09-30	2000-09-28	Kristallines 3-cephem derivat

Country Status (6)

Country	Link
US (1)	US6887992B2 (de)
EP (2)	EP1227100B1 (de)
KR (1)	KR100494825B1 (de)
AT (2)	ATE267831T1 (de)
HK (1)	HK1049480B (de)
WO (1)	WO2001023393A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040077849A1 (en) *	2002-10-16	2004-04-22	Orchid Chemicals & Pharmaceuticals Limited	Process for the preparation of cefadroxil
CN103622916B (zh) *	2013-12-19	2015-04-08	石家庄市华新药业有限责任公司	一种头孢克肟干混悬制剂及其制备方法
CN104045655B (zh) *	2014-06-23	2016-08-17	山东普洛得邦医药有限公司	一种抗菌素头孢母核的合成方法
CN104693217B (zh) *	2015-02-28	2017-01-11	浙江华方药业股份有限公司	一种头孢克肟的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH546794A (de)	1970-06-18	1974-03-15	Ciba Geigy Ag	Verfahren zur herstellung von cephalosporansaeurederivaten.
US3925372A (en) *	1973-02-23	1975-12-09	Lilly Co Eli	Alpha-aminoacyl-3-halo cephalosporins
DE3318194C2 (de) *	1983-05-19	1987-01-22	Fried. Krupp Gmbh, 4300 Essen	Verfahren zur Isolierung und Reinigung von Antibiotika
US4694079A (en) *	1985-07-29	1987-09-15	Bristol-Myers Company	3-propenyl cephalosporin solvates
JPH07121951B2 (ja) *	1986-04-15	1995-12-25	武田薬品工業株式会社	セファロスポリン系抗生物質の精製法
AU615966B2 (en) *	1987-12-04	1991-10-17	Takeda Chemical Industries Ltd.	Crystals of cephem hydrochloride
US5707634A (en) *	1988-10-05	1998-01-13	Pharmacia & Upjohn Company	Finely divided solid crystalline powders via precipitation into an anti-solvent
EP0638573A1 (de) *	1993-08-10	1995-02-15	Lucky Ltd.	Kristalline Hydrate eines Cephalosporins und Verfahren zu ihrer Herstellung
TW427993B (en) *	1993-09-09	2001-04-01	Fujisawa Pharmaceutical Co	New cephem compounds
GB9423459D0 (en) *	1994-11-21	1995-01-11	Biochemie Gmbh	Silylation process
ATE226954T1 (de) *	1998-03-27	2002-11-15	Dsm Nv	Verfahren zur fermentativen herstellung von cephalosporin
US6221153B1 (en) *	1998-06-09	2001-04-24	Trevor Percival Castor	Method for producing large crystals of complex molecules
TWI250160B (en) *	1999-07-06	2006-03-01	Sankyo Co	Crystalline 1-methylcarbapenem compound

2000
- 2000-09-28 AT AT00962912T patent/ATE267831T1/de active
- 2000-09-28 EP EP00962912A patent/EP1227100B1/de not_active Expired - Lifetime
- 2000-09-28 WO PCT/JP2000/006693 patent/WO2001023393A1/ja not_active Ceased
- 2000-09-28 EP EP04012048A patent/EP1447406B1/de not_active Expired - Lifetime
- 2000-09-28 KR KR10-2002-7003008A patent/KR100494825B1/ko not_active Expired - Fee Related
- 2000-09-28 HK HK03100779.4A patent/HK1049480B/en not_active IP Right Cessation
- 2000-09-28 AT AT04012048T patent/ATE335747T1/de active
2003
- 2003-10-07 US US10/679,451 patent/US6887992B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR20020032568A (ko)	2002-05-03
EP1227100A1 (de)	2002-07-31
EP1227100A4 (de)	2003-03-05
ATE335747T1 (de)	2006-09-15
EP1447406A1 (de)	2004-08-18
KR100494825B1 (ko)	2005-06-14
EP1447406B1 (de)	2006-08-09
HK1049480B (en)	2004-12-10
US6887992B2 (en)	2005-05-03
HK1049480A1 (en)	2003-05-16
EP1227100B1 (de)	2004-05-26
US20040073023A1 (en)	2004-04-15
WO2001023393A1 (en)	2001-04-05

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Legal Events

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2005-02-15

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