ATE268593T1 - Bupropionhydrochlorid enthaltende tabletten mit gesteuerter wirkstoffabgabe - Google Patents
Bupropionhydrochlorid enthaltende tabletten mit gesteuerter wirkstoffabgabeInfo
- Publication number
- ATE268593T1 ATE268593T1 AT99402455T AT99402455T ATE268593T1 AT E268593 T1 ATE268593 T1 AT E268593T1 AT 99402455 T AT99402455 T AT 99402455T AT 99402455 T AT99402455 T AT 99402455T AT E268593 T1 ATE268593 T1 AT E268593T1
- Authority
- AT
- Austria
- Prior art keywords
- controlled release
- bupropionhydrochloride
- tablets containing
- water
- free
- Prior art date
Links
- IKBZAUYPBWFMDI-UHFFFAOYSA-N 5-bromo-4-methoxy-7-methyl-2,3-dihydro-1h-indene Chemical compound C1=C(Br)C(OC)=C2CCCC2=C1C IKBZAUYPBWFMDI-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004367 bupropion hydrochloride Drugs 0.000 title abstract 2
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000011230 binding agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 239000000314 lubricant Substances 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 229920003169 water-soluble polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/184,096 US6033686A (en) | 1998-10-30 | 1998-10-30 | Controlled release tablet of bupropion hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268593T1 true ATE268593T1 (de) | 2004-06-15 |
Family
ID=22675529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99402455T ATE268593T1 (de) | 1998-10-30 | 1999-10-07 | Bupropionhydrochlorid enthaltende tabletten mit gesteuerter wirkstoffabgabe |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6033686A (de) |
| EP (2) | EP1004298B1 (de) |
| AT (1) | ATE268593T1 (de) |
| DE (2) | DE69937650T2 (de) |
| ES (2) | ES2295256T3 (de) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2758459B1 (fr) * | 1997-01-17 | 1999-05-07 | Pharma Pass | Composition pharmaceutique de fenofibrate presentant une biodisponibilite elevee et son procede de preparation |
| US8545880B2 (en) * | 1999-02-26 | 2013-10-01 | Andrx Pharmaceuticals, Llc | Controlled release oral dosage form |
| US20030044462A1 (en) * | 2001-08-20 | 2003-03-06 | Kali Laboratories, Inc. | Sustained release tablets containing bupropion hydrochloride |
| US20030091634A1 (en) * | 2001-09-14 | 2003-05-15 | Pawan Seth | Delayed release tablet of venlafaxin |
| US20030118647A1 (en) * | 2001-12-04 | 2003-06-26 | Pawan Seth | Extended release tablet of metformin |
| JP2005526079A (ja) * | 2002-03-15 | 2005-09-02 | サイプレス バイオサイエンス, インコーポレイテッド | 内蔵痛症候群を処置するためのneおよび5−ht再取り込み阻害剤 |
| IN192747B (de) * | 2002-04-15 | 2004-05-15 | Ranbaxy Lab Ltd | |
| US20050215552A1 (en) * | 2002-05-17 | 2005-09-29 | Gadde Kishore M | Method for treating obesity |
| US20040132826A1 (en) * | 2002-10-25 | 2004-07-08 | Collegium Pharmaceutical, Inc. | Modified release compositions of milnacipran |
| US20060003004A1 (en) * | 2002-10-25 | 2006-01-05 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
| US20040086567A1 (en) * | 2002-10-30 | 2004-05-06 | Pawan Seth | Bioequivalent composition of itraconazole and a hydrophilic polymer |
| US6893660B2 (en) * | 2002-11-21 | 2005-05-17 | Andrx Pharmaceuticals, Inc. | Stable pharmaceutical compositions without a stabilizer |
| US20040228830A1 (en) * | 2003-01-28 | 2004-11-18 | Collegium Pharmaceutical, Inc. | Multiparticulate compositions of milnacipran for oral administration |
| US20040162320A1 (en) * | 2003-02-14 | 2004-08-19 | Pawan Seth | Solid composition containing nisoldipine a mixture of polyethylene oxides and an antioxidant |
| RU2350327C2 (ru) | 2003-04-29 | 2009-03-27 | Ориксиджен Серапьютикс, Инкорпорэйтд | Составы, вызывающие потерю веса |
| RS51934B (sr) * | 2003-08-08 | 2012-02-29 | Biovail Laboratories International Srl. | Tableta bupropion hidrohlorida sa modifikovanim otpuštanjem |
| EP1523979A1 (de) * | 2003-10-13 | 2005-04-20 | Wyeth | Darreichungsform mit verlängerter Freisetzung |
| WO2005049003A1 (en) * | 2003-11-21 | 2005-06-02 | Ranbaxy Laboratories Limited | Extended release dosage forms of bupropion hydrochloride |
| US20060024362A1 (en) | 2004-07-29 | 2006-02-02 | Pawan Seth | Composition comprising a benzimidazole and process for its manufacture |
| US20060099262A1 (en) * | 2004-11-08 | 2006-05-11 | Biokey, Inc. | Methods and formulations for making controlled release oral dosage form |
| US8586085B2 (en) * | 2004-11-08 | 2013-11-19 | Biokey, Inc. | Methods and formulations for making pharmaceutical compositions containing bupropion |
| KR100670798B1 (ko) | 2004-12-17 | 2007-01-17 | 한국전자통신연구원 | 데이터베이스 캐시 시스템 |
| US7884136B2 (en) * | 2005-06-27 | 2011-02-08 | Biovail Laboratories International S.R.L. | Modified-release formulations of a bupropion salt |
| US7671094B2 (en) | 2005-06-27 | 2010-03-02 | Biovail Laboratories International S.R.L. | Bupropion hydrobromide and therapeutic applications |
| US7645802B2 (en) * | 2005-06-27 | 2010-01-12 | Biovail Laboratories International Srl. | Bupropion hydrobromide and therapeutic applications |
| EP1951212A2 (de) | 2005-11-22 | 2008-08-06 | Orexigen Therapeutics, Inc. | Zusammensetzungen und verfahren zur erhöhung der insulinsensitivität |
| AR057946A1 (es) * | 2005-11-28 | 2007-12-26 | Orexigen Therapeutics Inc | Formulacion de zonisamida de liberacion sostenidda |
| US8916195B2 (en) * | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| US20080069891A1 (en) * | 2006-09-15 | 2008-03-20 | Cima Labs, Inc. | Abuse resistant drug formulation |
| US8703191B2 (en) * | 2006-07-25 | 2014-04-22 | Intelgenx Corp. | Controlled-release pharmaceutical tablets |
| US7674479B2 (en) * | 2006-07-25 | 2010-03-09 | Intelgenx Corp. | Sustained-release bupropion and bupropion/mecamylamine tablets |
| US20100008987A1 (en) * | 2006-08-21 | 2010-01-14 | Pasula Basavaiah Chowdary | Modified Release Pharmaceutical Composition of Bupropion Hydrochloride |
| US8445018B2 (en) | 2006-09-15 | 2013-05-21 | Cima Labs Inc. | Abuse resistant drug formulation |
| CA2668885C (en) * | 2006-11-09 | 2016-08-02 | Orexigen Therapeutics, Inc. | Methods for administering weight loss medications |
| TW201811315A (zh) | 2006-11-09 | 2018-04-01 | 美商歐瑞根治療有限公司 | 層狀醫藥調配物 |
| EP2167065A1 (de) * | 2007-06-18 | 2010-03-31 | The General Hospital Corporation | Kombinationstherapie gegen depressionen |
| EP2303025A4 (de) | 2008-05-30 | 2012-07-04 | Orexigen Therapeutics Inc | Verfahren zur behandlung von eingeweidefettbeschwerden |
| JP2011526598A (ja) * | 2008-07-02 | 2011-10-13 | ビーエーエスエフ ソシエタス・ヨーロピア | 錠剤のコーティング方法 |
| US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
| US20110136815A1 (en) * | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| EP3659604A1 (de) * | 2010-01-11 | 2020-06-03 | Nalpropion Pharmaceuticals, Inc. | Verfahren zur bereitstellung einer gewichtsverlusttherapie für patienten mit schweren depressionen |
| PT3730132T (pt) | 2012-06-06 | 2022-08-16 | Nalpropion Pharmaceuticals Llc | Composição para utilização num método de tratamento de excesso de peso e obesidade em doentes com alto risco cardiovascular |
| WO2015065547A1 (en) | 2013-10-31 | 2015-05-07 | Cima Labs Inc. | Immediate release abuse-deterrent granulated dosage forms |
| WO2020225773A1 (en) | 2019-05-07 | 2020-11-12 | Clexio Biosciences Ltd. | Abuse-deterrent dosage forms containing esketamine |
| US20220062200A1 (en) | 2019-05-07 | 2022-03-03 | Clexio Biosciences Ltd. | Abuse-deterrent dosage forms containing esketamine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8322007D0 (en) * | 1983-08-16 | 1983-09-21 | Wellcome Found | Pharmaceutical delivery system |
| WO1985003436A1 (en) * | 1984-02-10 | 1985-08-15 | A/S Alfred Benzon | Diffusion coated multiple-units dosage form |
| US4769027A (en) * | 1984-08-15 | 1988-09-06 | Burroughs Wellcome Co. | Delivery system |
| CA1239034A (en) * | 1984-08-17 | 1988-07-12 | Kelly L. Smith | Delivery system |
| GB9217295D0 (en) * | 1992-08-14 | 1992-09-30 | Wellcome Found | Controlled released tablets |
| DE69425453T2 (de) * | 1993-04-23 | 2001-04-12 | Novartis Ag, Basel | Wirkstoffabgabevorrichtung mit gesteuerter Freigabe |
| US5358970A (en) * | 1993-08-12 | 1994-10-25 | Burroughs Wellcome Co. | Pharmaceutical composition containing bupropion hydrochloride and a stabilizer |
-
1998
- 1998-10-30 US US09/184,096 patent/US6033686A/en not_active Expired - Lifetime
-
1999
- 1999-10-07 DE DE69937650T patent/DE69937650T2/de not_active Expired - Lifetime
- 1999-10-07 ES ES02011246T patent/ES2295256T3/es not_active Expired - Lifetime
- 1999-10-07 EP EP99402455A patent/EP1004298B1/de not_active Expired - Lifetime
- 1999-10-07 EP EP02011246A patent/EP1232747B1/de not_active Expired - Lifetime
- 1999-10-07 ES ES99402455T patent/ES2222020T3/es not_active Expired - Lifetime
- 1999-10-07 DE DE69917866T patent/DE69917866T2/de not_active Expired - Lifetime
- 1999-10-07 AT AT99402455T patent/ATE268593T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2222020T3 (es) | 2005-01-16 |
| DE69937650D1 (de) | 2008-01-10 |
| DE69917866D1 (de) | 2004-07-15 |
| EP1004298A2 (de) | 2000-05-31 |
| EP1232747A3 (de) | 2003-01-29 |
| US6033686A (en) | 2000-03-07 |
| EP1004298B1 (de) | 2004-06-09 |
| EP1232747A2 (de) | 2002-08-21 |
| EP1004298A3 (de) | 2000-06-14 |
| EP1232747B1 (de) | 2007-11-28 |
| ES2295256T3 (es) | 2008-04-16 |
| DE69937650T2 (de) | 2008-07-17 |
| DE69917866T2 (de) | 2005-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |