ATE268771T1 - Verfahren zur herstellung von pyrazolopyridinderivaten - Google Patents
Verfahren zur herstellung von pyrazolopyridinderivatenInfo
- Publication number
- ATE268771T1 ATE268771T1 AT01932738T AT01932738T ATE268771T1 AT E268771 T1 ATE268771 T1 AT E268771T1 AT 01932738 T AT01932738 T AT 01932738T AT 01932738 T AT01932738 T AT 01932738T AT E268771 T1 ATE268771 T1 AT E268771T1
- Authority
- AT
- Austria
- Prior art keywords
- 6alkyl
- 6alkoxy
- substituted
- fluorine atoms
- halogen
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 150000005229 pyrazolopyridines Chemical class 0.000 title 1
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 abstract 6
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 6
- 125000001153 fluoro group Chemical group F* 0.000 abstract 4
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 3
- 125000004739 (C1-C6) alkylsulfonyl group Chemical group 0.000 abstract 1
- ZHKJHQBOAJQXQR-UHFFFAOYSA-N 1H-azirine Chemical compound N1C=C1 ZHKJHQBOAJQXQR-UHFFFAOYSA-N 0.000 abstract 1
- 125000006577 C1-C6 hydroxyalkyl group Chemical group 0.000 abstract 1
- 229910006074 SO2NH2 Inorganic materials 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 125000000565 sulfonamide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20040000P | 2000-04-28 | 2000-04-28 | |
| PCT/US2001/013801 WO2001083479A2 (en) | 2000-04-28 | 2001-04-27 | Process for the preparation of pyrazolopyridine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268771T1 true ATE268771T1 (de) | 2004-06-15 |
Family
ID=22741567
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01932738T ATE268771T1 (de) | 2000-04-28 | 2001-04-27 | Verfahren zur herstellung von pyrazolopyridinderivaten |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1276742B1 (de) |
| JP (1) | JP2003531906A (de) |
| AT (1) | ATE268771T1 (de) |
| AU (1) | AU2001259242A1 (de) |
| DE (1) | DE60103752T2 (de) |
| ES (1) | ES2222372T3 (de) |
| WO (1) | WO2001083479A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20020506A1 (es) | 2000-08-22 | 2002-07-09 | Glaxo Group Ltd | Derivados de pirazol fusionados como inhibidores de la proteina cinasa |
| DE60305053T2 (de) | 2002-08-19 | 2006-08-31 | Glaxo Group Ltd., Greenford | Pyrimidinderivate als selektive cox-2-inhibitoren |
| GB0221443D0 (en) | 2002-09-16 | 2002-10-23 | Glaxo Group Ltd | Pyridine derivates |
| UA103319C2 (en) | 2008-05-06 | 2013-10-10 | Глаксосмитклайн Ллк | Thiazole- and oxazole-benzene sulfonamide compounds |
| FR2950345B1 (fr) * | 2009-09-18 | 2011-09-23 | Sanofi Aventis | Derives acetyleniques de 5-phenyl-pyrazolopyridine, leur preparation et leur application en therapeutique |
| US8871754B2 (en) | 2012-11-19 | 2014-10-28 | Irm Llc | Compounds and compositions for the treatment of parasitic diseases |
| WO2014078802A1 (en) | 2012-11-19 | 2014-05-22 | Irm Llc | Compounds and compositions for the treatment of parasitic diseases |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4821117B1 (de) * | 1970-09-25 | 1973-06-26 | ||
| JPS5753486A (en) * | 1980-09-17 | 1982-03-30 | Mitsubishi Paper Mills Ltd | Preparation of 3-formyl-pyrazolo 1,5-a pyridine derivative |
| JPS57126489A (en) * | 1981-01-28 | 1982-08-06 | Mitsubishi Paper Mills Ltd | Preparation of pyrazolo(1, 5-a)pyridine derivative |
| JPS60248689A (ja) * | 1984-05-24 | 1985-12-09 | Mitsubishi Paper Mills Ltd | ３−（３′−ピラゾロ〔１，５−ａ〕ピリジル）アクロレイン誘導体 |
-
2001
- 2001-04-27 AU AU2001259242A patent/AU2001259242A1/en not_active Abandoned
- 2001-04-27 JP JP2001580907A patent/JP2003531906A/ja active Pending
- 2001-04-27 WO PCT/US2001/013801 patent/WO2001083479A2/en not_active Ceased
- 2001-04-27 EP EP01932738A patent/EP1276742B1/de not_active Expired - Lifetime
- 2001-04-27 AT AT01932738T patent/ATE268771T1/de not_active IP Right Cessation
- 2001-04-27 DE DE60103752T patent/DE60103752T2/de not_active Expired - Lifetime
- 2001-04-27 ES ES01932738T patent/ES2222372T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003531906A (ja) | 2003-10-28 |
| EP1276742A2 (de) | 2003-01-22 |
| AU2001259242A1 (en) | 2001-11-12 |
| EP1276742B1 (de) | 2004-06-09 |
| WO2001083479A2 (en) | 2001-11-08 |
| DE60103752T2 (de) | 2005-07-14 |
| DE60103752D1 (de) | 2004-07-15 |
| ES2222372T3 (es) | 2005-02-01 |
| WO2001083479A3 (en) | 2002-05-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |