ATE269086T1 - Antibiotische steroidderivate - Google Patents

Antibiotische steroidderivate

Info

Publication number
ATE269086T1
ATE269086T1 AT98909028T AT98909028T ATE269086T1 AT E269086 T1 ATE269086 T1 AT E269086T1 AT 98909028 T AT98909028 T AT 98909028T AT 98909028 T AT98909028 T AT 98909028T AT E269086 T1 ATE269086 T1 AT E269086T1
Authority
AT
Austria
Prior art keywords
steroid derivatives
antibiotic steroid
antibiotic
derivatives
erythromicin
Prior art date
Application number
AT98909028T
Other languages
English (en)
Inventor
Paul B Savage
Chunhong Li
Original Assignee
Univ Brigham Young
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brigham Young filed Critical Univ Brigham Young
Application granted granted Critical
Publication of ATE269086T1 publication Critical patent/ATE269086T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT98909028T 1998-03-06 1998-03-06 Antibiotische steroidderivate ATE269086T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/004489 WO1999044616A1 (en) 1998-03-06 1998-03-06 Steroid derived antibiotics

Publications (1)

Publication Number Publication Date
ATE269086T1 true ATE269086T1 (de) 2004-07-15

Family

ID=22266538

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98909028T ATE269086T1 (de) 1998-03-06 1998-03-06 Antibiotische steroidderivate

Country Status (9)

Country Link
EP (1) EP1058552B1 (de)
JP (1) JP2002505292A (de)
CN (1) CN100398109C (de)
AT (1) ATE269086T1 (de)
AU (1) AU759333B2 (de)
BR (1) BR9815711B1 (de)
CA (1) CA2322847C (de)
DE (1) DE69824638T2 (de)
WO (1) WO1999044616A1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350738B1 (en) * 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics
JP2003512474A (ja) * 1999-10-25 2003-04-02 ホリス − イーデン ファーマスーティカルズ、 インコーポレイテッド 血液細胞欠乏症の治療処置
EP1278763B1 (de) 2000-04-28 2007-02-14 Inflazyme Pharmaceuticals, Ltd. 3-stickstoff-6,7-dioxygenierte steroid verbindungen und verwendungen davon
CA2419801C (en) * 2000-08-15 2010-08-10 Brigham Young University Steroid derived antibiotics
US7141559B2 (en) 2002-06-19 2006-11-28 Karo Bio Ab Glucocorticoid receptor ligands for the treatment of metabolic disorders
KR100552567B1 (ko) * 2003-08-23 2006-02-15 한국유나이티드제약 주식회사 수분 흡수에 안정하고 빠르게 붕해되는 세푸록심 악세틸을포함하는 정제의 조성물 및 제조 방법
US9943614B2 (en) 2008-06-17 2018-04-17 Brigham Young University Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods
CN104053458B (zh) 2011-07-20 2016-07-20 布莱阿姆青年大学 包含洗脱塞拉集宁化合物的水凝胶材料
US8945217B2 (en) 2011-08-25 2015-02-03 Brigham Young University Medical devices incorporating ceragenin-containing composites
EP2755661A1 (de) 2011-09-13 2014-07-23 Brigham Young University Zusammensetzungen zur behandlung von knochenkrankheiten und gebrochenen knochen
US9603859B2 (en) 2011-09-13 2017-03-28 Brigham Young University Methods and products for increasing the rate of healing of tissue wounds
US9694019B2 (en) 2011-09-13 2017-07-04 Brigham Young University Compositions and methods for treating bone diseases and broken bones
MX369385B (es) 2011-09-13 2019-11-07 Univ Brigham Young Productos para cicatrizar heridas tisulares.
KR20140116111A (ko) * 2011-12-21 2014-10-01 브라이엄 영 유니버시티 구강 관리 조성물
US9533063B1 (en) 2012-03-01 2017-01-03 Brigham Young University Aerosols incorporating ceragenin compounds and methods of use thereof
US20130280391A1 (en) * 2012-04-24 2013-10-24 Brigham Young University Anti-microbial wash compositions including ceragenin compounds and methods of use for treating non-meat food products
US10039285B2 (en) 2012-05-02 2018-08-07 Brigham Young University Ceragenin particulate materials and methods for making same
EP2908826A1 (de) 2012-10-17 2015-08-26 Brigham Young University Behandlung und prävention von mastitis
JP6294352B2 (ja) 2013-01-07 2018-03-14 ブリガム・ヤング・ユニバーシティＢｒｉｇｈａｍ Ｙｏｕｎｇ Ｕｎｉｖｅｒｓｉｔｙ 細胞増殖を減少させ、ある特定の疾患を治療する方法
WO2014151411A1 (en) 2013-03-15 2014-09-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US9387215B2 (en) 2013-04-22 2016-07-12 Brigham Young University Animal feed including cationic cholesterol additive and related methods
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9867836B2 (en) 2014-03-13 2018-01-16 Brigham Young University Lavage and/or infusion using CSA compounds for increasing fertility in a mammal
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
US9686966B2 (en) 2014-04-30 2017-06-27 Brigham Young University Methods and apparatus for cleaning or disinfecting a water delivery system
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
US10370403B2 (en) 2015-04-22 2019-08-06 Brigham Young University Methods for the synthesis of ceragenins
US9527883B2 (en) 2015-04-22 2016-12-27 Brigham Young University Methods for the synthesis of ceragenins
US9434759B1 (en) 2015-05-18 2016-09-06 Brigham Young University Cationic steroidal antimicrobial compounds and methods of manufacturing such compounds
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
JP2017031201A (ja) * 2016-09-30 2017-02-09 ブリガム ヤング ユニバーシティ 口腔ケア組成物
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
US12186328B2 (en) 2019-05-23 2025-01-07 Brigham Young University Use of CSA compounds to stimulate stem cells and hair growth

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3519714A (en) * 1966-03-15 1970-07-07 Herchel Smith Synthesis of gona-1,3,5(10)-trienes
US4192871A (en) * 1976-01-06 1980-03-11 Glaxo Laboratories Limited Chemical compounds
WO1994020520A1 (en) * 1993-03-10 1994-09-15 Magainin Pharmaceuticals Inc. Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants
JPH09511486A (ja) * 1994-01-13 1997-11-18 ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨーク 合成レセプター、ライブラリー及びこれらの使用
ES2164110T3 (es) * 1994-03-10 2002-02-16 Magainin Pharma Usos farmaceuticos de derivados de esteroides.
US5834453A (en) * 1995-05-30 1998-11-10 Lehigh University Methods for the manufacture and use of antimicrobial sterol conjugates

Also Published As

Publication number Publication date
EP1058552B1 (de) 2004-06-16
AU759333B2 (en) 2003-04-10
CA2322847C (en) 2008-05-13
JP2002505292A (ja) 2002-02-19
CN1294514A (zh) 2001-05-09
DE69824638T2 (de) 2005-06-23
CA2322847A1 (en) 1999-09-10
AU6691198A (en) 1999-09-20
BR9815711B1 (pt) 2014-10-29
BR9815711A (pt) 2001-11-13
EP1058552A4 (de) 2001-09-19
WO1999044616A1 (en) 1999-09-10
EP1058552A1 (de) 2000-12-13
DE69824638D1 (de) 2004-07-22
CN100398109C (zh) 2008-07-02

Similar Documents

Publication Publication Date Title
ATE269086T1 (de) Antibiotische steroidderivate
GEP19991836B (en) Novel Erythromicin Derivatives, Method for Preparing Same and Pharmaceutical Composition on its Basis
ES2161220T3 (es) 9-((glicil sustituido)amido)-6-desmetil-6-desoxitetraciclinas como agentes antibioticos.
UY26870A1 (es) Antibióticos macrólidos
ATE349464T1 (de) Derivate von glykopeptidantibiotika
ES2131496T3 (es) Mejoras relativas a derivados glicopeptidicos.
DE69928952D1 (de) Chinolin-derivate und ihre verwendung als antibakterielle wirkstoffe
FR11C0037I2 (fr) Antibiotiques macrolides et traitement de la pasteurellose
ATE133179T1 (de) Steroid-sulfatase-inhibitoren
ES2191208T3 (es) Oxiimino-pregnano-carbolactonas.
ES2106965T3 (es) Nuevas 4-aza-5alfa-androstan-3-onas 7beta-sustituidas como inhibidores de 5alfa-reductasa.
ATE277063T1 (de) 6-o-alkylerythromycinoxim b
BR0007514A (pt) Macrolìdeos com atividade anti-inflamatória
ATE66001T1 (de) Makrolid-antibiotikaderivate.
TR200003587T2 (tr) Nosatiasin antibiyotikleri.
YU175791A (sh) Heterociklični derivati monocikličnih beta laktam antibiotika
DE3780644D1 (de) Glykopeptid-antibiotika.
RU95101041A (ru) Липосомные растворы
ES2048793T3 (es) Antibioticos antifungicos.
AU4714297A (en) Metalloproteinase inhibitors
DE69936052D1 (de) N1 modifizierte glycopeptide
ATE90105T1 (de) Glycosid-antibiotika bu-3608d und bu-3608e.
TR199701298T1 (xx) Tetralinler.
BR9811674A (pt) Solvatos oxima de eritromicina a
PT1104419E (pt) Derivados de azabicicloheptano substituidos no azoto sua preparacao e utilizacao

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties