ATE349464T1 - Derivate von glykopeptidantibiotika - Google Patents

Derivate von glykopeptidantibiotika

Info

Publication number
ATE349464T1
ATE349464T1 AT96909713T AT96909713T ATE349464T1 AT E349464 T1 ATE349464 T1 AT E349464T1 AT 96909713 T AT96909713 T AT 96909713T AT 96909713 T AT96909713 T AT 96909713T AT E349464 T1 ATE349464 T1 AT E349464T1
Authority
AT
Austria
Prior art keywords
derivatives
derivative compounds
glycopeptide antibiotics
activity against
glycopeptide antibiotic
Prior art date
Application number
AT96909713T
Other languages
English (en)
Inventor
Robin D G Cooper
Bret E Huff
Thalia I Nicas
John T Quatroche
Michael J Rodriguez
Nancy J Snyder
Michael A Staszak
Richard C Thompson
Stephen C Wilkie
Mark J Zweifel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE349464T1 publication Critical patent/ATE349464T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT96909713T 1995-03-24 1996-03-14 Derivate von glykopeptidantibiotika ATE349464T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/410,155 US5840684A (en) 1994-01-28 1995-03-24 Glycopeptide antibiotic derivatives

Publications (1)

Publication Number Publication Date
ATE349464T1 true ATE349464T1 (de) 2007-01-15

Family

ID=23623466

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96909713T ATE349464T1 (de) 1995-03-24 1996-03-14 Derivate von glykopeptidantibiotika

Country Status (10)

Country Link
US (2) US5840684A (de)
EP (1) EP0817797B1 (de)
JP (1) JPH11502534A (de)
AT (1) ATE349464T1 (de)
AU (1) AU5312196A (de)
DE (1) DE69636791T2 (de)
DK (1) DK0817797T3 (de)
ES (1) ES2274525T3 (de)
PT (1) PT817797E (de)
WO (1) WO1996030401A1 (de)

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US5977063A (en) * 1997-05-20 1999-11-02 Eli Lilly And Company Alkylated hexapeptides
US6518242B1 (en) * 1998-02-20 2003-02-11 Theravance, Inc. Derivatives of glycopeptide antibacterial agents
HUP0101830A3 (en) * 1998-05-05 2002-10-28 Lilly Co Eli Purification carboxaldehyde
US6392012B1 (en) * 1998-12-23 2002-05-21 Advanced Medicine, Inc. Glycopeptide derivatives and pharmaceutical compositions containing the same
AU2606700A (en) * 1999-01-12 2000-08-01 Princeton University Saccharides linked to compounds that bind cell-surface peptides or proteins
US6699836B2 (en) 1999-04-02 2004-03-02 The Trustees Of Princeton University Vancomycin analogs
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EP1276759B1 (de) * 2000-05-02 2008-07-30 Theravance, Inc. Verfahren zur reduktiven alkylierung von glykopeptiden
WO2001083520A2 (en) * 2000-05-02 2001-11-08 Theravance,Inc Polyacid glycopeptide derivatives
DE60136926D1 (de) * 2000-05-02 2009-01-22 Theravance Inc Zusammensetzung die eine zyklodextrin und ein glykopeptid-antibiotikum enthält
EP1154663B1 (de) * 2000-05-09 2008-09-24 Lucent Technologies Inc. Verbesserte Steurung der Dienstequalität in einem mobilen Telekommunikationsnetz
US6872804B2 (en) * 2000-06-22 2005-03-29 Theravance, Inc. Glycopeptide disulfide and thioester derivatives
ES2302733T3 (es) * 2000-06-22 2008-08-01 Theravance, Inc. Derivados carboxi-sacaridos de glucopeptido.
UA75083C2 (uk) * 2000-06-22 2006-03-15 Тераванс, Інк. Похідні глікопептидфосфонатів
AU2001259816A1 (en) 2000-06-22 2002-01-02 Advanced Medecine, Inc. Polyhydroxy glycopeptide derivatives
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WO2004019970A2 (en) * 2002-08-30 2004-03-11 K.U. Leuven Research And Development Glycopeptide antibiotic and semisynthetic derivatives thereof and their use as antiviral agents
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WO2006057303A1 (ja) 2004-11-29 2006-06-01 National University Corporation Nagoya University グリコペプチド抗生物質モノマー誘導体
US7632918B2 (en) * 2005-02-28 2009-12-15 Novartis Vaccines And Diagnostics, Inc. Semi-synthetic glycopeptides with antibiotic activity
US20070185015A1 (en) * 2005-02-28 2007-08-09 Chiron Corporation and North China Pharmaceutical Corporation Semi-synthetic desmethyl-vancomycin-based glycopeptides with antibiotic activity
US7368422B2 (en) * 2005-02-28 2008-05-06 Novartis Vaccines And Diagnostics Inc. Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity
UA90707C2 (en) * 2005-04-06 2010-05-25 Астразенека Аб Novel 5-substituted 7-amino-[1,3]thiazolo[4,5-d]pyrimidine derivatives
AR053347A1 (es) * 2005-04-06 2007-05-02 Astrazeneca Ab Derivados de [1,3]tiazolo[4,5-d]pirimidin-2(3h)-ona 5,7-sustituidos
WO2007038246A2 (en) 2005-09-22 2007-04-05 Medivas, Llc Solid polymer delivery compositions and methods for use thereof
CA2623198C (en) 2005-09-22 2014-08-05 Medivas, Llc Bis-(a-amino)-diol-diester-containing poly(ester amide) and poly(ester urethane) compositions and methods of use
US20070173438A1 (en) * 2006-01-13 2007-07-26 The Scripps Research Institute [PSI[CH2NH]PG4] glycopeptide antibiotic analogs
TW200808818A (en) 2006-05-26 2008-02-16 Shionogi & Co Glycopeptide antibiotic derivatives
CA2664444C (en) 2006-09-25 2015-10-27 Melinta Therapeutics, Inc. Use of oritavancin for prevention and treatment of anthrax
EP2097440A4 (de) * 2006-12-22 2010-09-08 Targanta Therapeutics Inc Phosphonierte glycopeptid- und lipoglycopeptidantibiotika und deren verwendung zur prävention und behandlung von knochen- und gelenkinfektionen
AU2008342149A1 (en) * 2007-12-26 2009-07-02 Shionogi & Co., Ltd. Glycosylated glycopeptide antibiotic derivative
US8841440B2 (en) 2008-04-01 2014-09-23 Cornell University Organo-soluble chitosan salts and chitosan-derived biomaterials prepared thereof
ES2884673T3 (es) 2008-04-08 2021-12-10 Melinta Therapeutics Inc Oritavancina para inhibir y tratar biopelículas
JP5782615B2 (ja) 2008-08-30 2015-09-24 ザ メディシンズ カンパニー オリタバンシンの単回用量を用いる治療の方法
PT2424559T (pt) 2009-04-28 2024-04-30 Melinta Therapeutics Llc Métodos de tratamento de infeções bacterianas utilizando oritavancina
WO2013016529A2 (en) 2011-07-26 2013-01-31 The Medicines Company Disk diffusion assay for oritavancin
WO2014152332A1 (en) 2013-03-15 2014-09-25 Melinta Therapeutics, Inc. Methods of treating infections in overweight and obese patients using antibiotics
CN107759672A (zh) * 2013-08-19 2018-03-06 南京爱斯药业有限公司 万古霉素衍生物、制备方法及其应用
LT3038616T (lt) 2013-08-26 2023-05-25 Melinta Therapeutics, Inc. Bakteriemijos ir osteomielito gydymo būdai naudojant oritavanciną
WO2015040467A1 (en) 2013-09-23 2015-03-26 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Vancomycin-sugar conjugates and uses thereof
GB201402267D0 (en) 2014-02-10 2014-03-26 Cambridge Entpr Ltd Antibacterial agents
WO2016007855A1 (en) * 2014-07-10 2016-01-14 The Scripps Research Institute N- (hydrophobe-substituted) vancosaminyl [ψ[c(=nh) nh] tpg4] vancomycin and [ψ[ch2nh]tpg4] vancomycin
MX385925B (es) 2014-07-17 2025-03-18 The Medicines Co Oritavancina de alta pureza y método para producir la misma.
CA2972276A1 (en) * 2014-12-25 2016-06-30 Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR) Glycopeptides and uses thereof
US10561648B2 (en) * 2016-01-11 2020-02-18 Stc.Unm Inhibition and treatment of bacterial infections by sex-specific GPER targeting
JP6671972B2 (ja) * 2016-01-15 2020-03-25 キヤノン株式会社 ファクシミリ装置、閾値設定方法、及びプログラム
CA3014294A1 (en) 2016-02-18 2017-08-24 Melinta Therapeutics, Inc. Oritavancin formulations
WO2017179003A1 (en) 2016-04-15 2017-10-19 Lupin Limited Topical compositions for ophthalmic and otic use
CN107619432B (zh) * 2016-07-15 2023-03-17 上海来益生物药物研究开发中心有限责任公司 糖肽类衍生物及其药学可接受的盐、制备方法和应用
CN108409837B (zh) * 2018-03-06 2021-09-24 上海来益生物药物研究开发中心有限责任公司 一组具有抗耐药性细菌活性的糖肽类化合物、其制备方法和应用

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Also Published As

Publication number Publication date
EP0817797A1 (de) 1998-01-14
DE69636791D1 (de) 2007-02-08
EP0817797B1 (de) 2006-12-27
JPH11502534A (ja) 1999-03-02
PT817797E (pt) 2007-02-28
ES2274525T3 (es) 2007-05-16
DK0817797T3 (da) 2007-05-07
EP0817797A4 (de) 2000-12-06
WO1996030401A1 (en) 1996-10-03
US5840684A (en) 1998-11-24
DE69636791T2 (de) 2007-10-11
AU5312196A (en) 1996-10-16
US5977062A (en) 1999-11-02

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