ATE269847T1 - Verfahren zur herstellung von 13-cis retinsaüre - Google Patents

Verfahren zur herstellung von 13-cis retinsaüre

Info

Publication number
ATE269847T1
ATE269847T1 AT99914082T AT99914082T ATE269847T1 AT E269847 T1 ATE269847 T1 AT E269847T1 AT 99914082 T AT99914082 T AT 99914082T AT 99914082 T AT99914082 T AT 99914082T AT E269847 T1 ATE269847 T1 AT E269847T1
Authority
AT
Austria
Prior art keywords
producing
acid
cis
retin
present
Prior art date
Application number
AT99914082T
Other languages
English (en)
Inventor
Xiu C Wang
Ashok V Bhatia
Azad Hossain
Timothy B Towne
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE269847T1 publication Critical patent/ATE269847T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT99914082T 1998-03-25 1999-03-23 Verfahren zur herstellung von 13-cis retinsaüre ATE269847T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/047,700 US6124485A (en) 1998-03-25 1998-03-25 Process for producing 13-cis retinoic acid
PCT/US1999/006385 WO1999048866A1 (en) 1998-03-25 1999-03-23 Process for producing 13-cis retinoic acid

Publications (1)

Publication Number Publication Date
ATE269847T1 true ATE269847T1 (de) 2004-07-15

Family

ID=21950449

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99914082T ATE269847T1 (de) 1998-03-25 1999-03-23 Verfahren zur herstellung von 13-cis retinsaüre

Country Status (9)

Country Link
US (2) US6124485A (de)
EP (1) EP1066253B1 (de)
JP (1) JP4532734B2 (de)
AT (1) ATE269847T1 (de)
CA (1) CA2325517A1 (de)
DE (1) DE69918277T2 (de)
ES (1) ES2229691T3 (de)
PT (1) PT1066253E (de)
WO (1) WO1999048866A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102558007B (zh) * 2011-12-31 2014-02-26 湖南师范大学 一种全反式维a酸类药物的合成方法
CN104447459A (zh) * 2014-11-28 2015-03-25 重庆华邦制药有限公司 异维a酸的新晶型及其制备方法与应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK170945B1 (da) * 1982-12-10 1996-03-25 Hoffmann La Roche Fremgangsmåde til fremstilling af 13-cisretinsyre og fremgangsmåde til fremstilling af en palladiumkatalysator til brug ved fremgangsmåden
US4556518A (en) * 1982-12-10 1985-12-03 Hoffmann-La Roche Inc. Preparation of 13-cis retinoic acid
US4556578A (en) * 1983-06-30 1985-12-03 Mallinckrodt, Inc. NaCl-Free salt substitute containing potassium chloride, maltodextrin and potassium bitartrate and method of preparation
US5191110A (en) * 1987-05-21 1993-03-02 L'oreal Process for the synthesis of vitamin A and certain ones of derivatives
US5061819A (en) * 1988-10-31 1991-10-29 Loyola University Of Chicago Methods for synthesizing phosphonate reagents and retinoids
US4916250A (en) * 1988-10-31 1990-04-10 Loyola University Of Chicago Phosphonate reagent compositions
JP3159413B2 (ja) * 1993-01-20 2001-04-23 株式会社クラレ ３−置換−４−ヒドロキシ−２−ブテノライドの製造方法
DE4313089A1 (de) * 1993-04-22 1994-10-27 Basf Ag Verfahren zur Herstellung von 13-(Z)-Retinsäure
JP3599403B2 (ja) * 1995-02-24 2004-12-08 山之内製薬株式会社 ベンズアゼピン誘導体の新規製造法
IT1274494B (it) * 1995-05-12 1997-07-17 Lab Mag Spa Procedimento fotochimico per la preparazione dell'acido 13-cis-retinoico
JPH10298173A (ja) * 1997-04-30 1998-11-10 Kuraray Co Ltd ４−ヒドロキシ−２−ブテノリド類の製造方法

Also Published As

Publication number Publication date
EP1066253B1 (de) 2004-06-23
DE69918277T2 (de) 2005-07-14
JP4532734B2 (ja) 2010-08-25
US20010018533A1 (en) 2001-08-30
EP1066253A1 (de) 2001-01-10
PT1066253E (pt) 2004-10-29
CA2325517A1 (en) 1999-09-30
JP2002507596A (ja) 2002-03-12
DE69918277D1 (de) 2004-07-29
ES2229691T3 (es) 2005-04-16
US6124485A (en) 2000-09-26
WO1999048866A1 (en) 1999-09-30

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