ATE269851T1 - Benzimidazole derivate - Google Patents

Benzimidazole derivate

Info

Publication number
ATE269851T1
ATE269851T1 AT98917745T AT98917745T ATE269851T1 AT E269851 T1 ATE269851 T1 AT E269851T1 AT 98917745 T AT98917745 T AT 98917745T AT 98917745 T AT98917745 T AT 98917745T AT E269851 T1 ATE269851 T1 AT E269851T1
Authority
AT
Austria
Prior art keywords
group
substituted
optionally
alkyl group
alkylene
Prior art date
Application number
AT98917745T
Other languages
English (en)
Inventor
Keizo Tanikawa
- Tsuboi-Cho Institute
Yoshimasa Kamikawaji
Mitsuaki Hirotsuka
Takehisa Iwama
Kenkyusho Seibutsukagaku
Akiko Yamamoto
Yoichiro Fujita
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Application granted granted Critical
Publication of ATE269851T1 publication Critical patent/ATE269851T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/14—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT98917745T 1997-05-01 1998-04-30 Benzimidazole derivate ATE269851T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP11372397 1997-05-01
JP5530398 1998-03-06
PCT/JP1998/001986 WO1998050368A1 (en) 1997-05-01 1998-04-30 Benzimidazole derivative

Publications (1)

Publication Number Publication Date
ATE269851T1 true ATE269851T1 (de) 2004-07-15

Family

ID=26396198

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98917745T ATE269851T1 (de) 1997-05-01 1998-04-30 Benzimidazole derivate

Country Status (15)

Country Link
US (1) US6114369A (de)
EP (1) EP0980359B1 (de)
KR (1) KR100530208B1 (de)
CN (1) CN1095836C (de)
AT (1) ATE269851T1 (de)
AU (1) AU730650B2 (de)
CA (1) CA2285535C (de)
DE (1) DE69824722T2 (de)
HU (1) HUP0001010A3 (de)
IL (1) IL132575A0 (de)
NO (1) NO995289D0 (de)
NZ (1) NZ337749A (de)
RU (1) RU2188822C2 (de)
SK (1) SK146699A3 (de)
WO (1) WO1998050368A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002096853A1 (fr) * 2001-05-28 2002-12-05 Ihara Chemical Industry Co., Ltd. Procede de production d'un derive d'aralkylamine
US7118765B2 (en) * 2001-12-17 2006-10-10 Spi Pharma, Inc. Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms
DE10207844A1 (de) * 2002-02-15 2003-09-04 Schering Ag 1-Phenyl-2-heteroaryl-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate
DE60319813T2 (de) * 2002-04-18 2009-04-23 Schering Corporation 1-(4-piperidinyl)benzimidazole als histamin h3 antagonisten
FR2851563B1 (fr) * 2003-02-26 2005-04-22 Sod Conseils Rech Applic Nouveaux derives de benzimidazole et d'imidazo-pyridine et leur utilisation en tant que medicament
US7419996B2 (en) * 2003-08-13 2008-09-02 The University Of Houston Parenteral and oral formulations of benzimidazoles
US7291744B2 (en) * 2003-11-13 2007-11-06 Bristol-Myers Squibb Company N-ureidoalkyl-amino compounds as modulators of chemokine receptor activity
MX2011009053A (es) 2009-03-09 2012-04-02 Spi Pharma Inc Excipientes de compresion directa con alta capacidad de compactacion y durables y sistemas de excipiente.
RU2423355C2 (ru) * 2009-09-17 2011-07-10 Федеральное государственное образовательное учреждение высшего профессионального образования "Южный Федеральный университет" (ЮФУ) Министерства науки и образования Российской Федерации, Федерального агентства по образованию 1,3-дизамещенные 2-иминобензимидазолина, обладающие антибактериальным действием
CN103121969A (zh) * 2012-12-04 2013-05-29 中国科学院昆明植物研究所 苯并咪唑及其衍生物，其药物组合物及其应用
CN103121970B (zh) * 2012-12-04 2015-04-29 中国科学院昆明植物研究所 苯并咪唑及其衍生物，其药物组合物及其在制备抗抑郁药物中的应用
RU2711098C1 (ru) * 2019-04-15 2020-01-15 Федеральное государственное бюджетное научное учреждение "Федеральный Ростовский аграрный научный центр" (ФГБНУ ФРАНЦ) Производные нитропиридина, обладающие антибактериальной и протистоцидной активностью

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2244500B1 (de) * 1973-07-03 1977-07-01 Delalande Sa
EP0144101B1 (de) * 1983-11-30 1991-02-06 Janssen Pharmaceutica N.V. Bizyklisches Heterozyklyl aufveisende N-(bizyklisches Heterozyklyl-4-piperidinamine
US5290801A (en) * 1992-05-29 1994-03-01 The Du Pont Merck Pharmaceutical Company Benzimidazoles for the treatment of atherosclerosis
US5478858A (en) * 1993-12-17 1995-12-26 The Procter & Gamble Company 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists
JPH09124609A (ja) * 1995-11-07 1997-05-13 Nissan Chem Ind Ltd ベンズイミダゾール誘導体

Also Published As

Publication number Publication date
CN1253549A (zh) 2000-05-17
NZ337749A (en) 2000-09-29
US6114369A (en) 2000-09-05
CA2285535A1 (en) 1998-11-12
IL132575A0 (en) 2001-03-19
EP0980359A1 (de) 2000-02-23
WO1998050368A1 (en) 1998-11-12
DE69824722T2 (de) 2004-12-09
SK146699A3 (en) 2000-05-16
NO995289L (no) 1999-10-29
DE69824722D1 (de) 2004-07-29
RU2188822C2 (ru) 2002-09-10
KR100530208B1 (ko) 2005-11-22
CN1095836C (zh) 2002-12-11
HUP0001010A3 (en) 2001-06-28
AU7083098A (en) 1998-11-27
EP0980359B1 (de) 2004-06-23
HUP0001010A2 (hu) 2001-04-28
NO995289D0 (no) 1999-10-29
CA2285535C (en) 2006-08-15
AU730650B2 (en) 2001-03-08
KR20010020281A (ko) 2001-03-15

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties