ATE269895T1 - Erhöhung des trehalosegehaltes in organismen durch transformation mit kombinierten strukturgenen der trehalosesynthase - Google Patents

Erhöhung des trehalosegehaltes in organismen durch transformation mit kombinierten strukturgenen der trehalosesynthase

Info

Publication number
ATE269895T1
ATE269895T1 AT93904049T AT93904049T ATE269895T1 AT E269895 T1 ATE269895 T1 AT E269895T1 AT 93904049 T AT93904049 T AT 93904049T AT 93904049 T AT93904049 T AT 93904049T AT E269895 T1 ATE269895 T1 AT E269895T1
Authority
AT
Austria
Prior art keywords
trehalose
organisms
transformation
increasing
synthase
Prior art date
Application number
AT93904049T
Other languages
English (en)
Inventor
John Londesborough
Outi Vuorio
Original Assignee
Btg Int Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Btg Int Ltd filed Critical Btg Int Ltd
Application granted granted Critical
Publication of ATE269895T1 publication Critical patent/ATE269895T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C12N9/92—Glucose isomerase (5.3.1.5; 5.3.1.9; 5.3.1.18)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces
    • Y10S435/942—Saccharomyces cerevisiae

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dairy Products (AREA)
AT93904049T 1992-02-14 1993-02-15 Erhöhung des trehalosegehaltes in organismen durch transformation mit kombinierten strukturgenen der trehalosesynthase ATE269895T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83602192A 1992-02-14 1992-02-14
US07/841,997 US5422254A (en) 1992-02-14 1992-02-28 Method to increase the trehalose content of organisms by transforming them with the structural genes for the short and long chains of yeast trehalose synthase
PCT/FI1993/000049 WO1993017093A2 (en) 1992-02-14 1993-02-15 Increasing the trehalose content of organisms by transforming them with combinations of the structural genes for trehalose synthase

Publications (1)

Publication Number Publication Date
ATE269895T1 true ATE269895T1 (de) 2004-07-15

Family

ID=27125836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93904049T ATE269895T1 (de) 1992-02-14 1993-02-15 Erhöhung des trehalosegehaltes in organismen durch transformation mit kombinierten strukturgenen der trehalosesynthase

Country Status (10)

Country Link
US (1) US5422254A (de)
EP (1) EP0635051B1 (de)
JP (1) JPH07503853A (de)
AT (1) ATE269895T1 (de)
AU (1) AU677175B2 (de)
CA (1) CA2130082A1 (de)
DE (1) DE69333559D1 (de)
FI (1) FI943739A7 (de)
NZ (1) NZ249133A (de)
WO (1) WO1993017093A2 (de)

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US7705215B1 (en) 1990-04-17 2010-04-27 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US6803499B1 (en) 1989-08-09 2004-10-12 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US6777589B1 (en) 1990-01-22 2004-08-17 Dekalb Genetics Corporation Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
US6329574B1 (en) 1990-01-22 2001-12-11 Dekalb Genetics Corporation High lysine fertile transgenic corn plants
JP3209744B2 (ja) * 1990-01-22 2001-09-17 デカルブ・ジェネティクス・コーポレーション 結実能力のある遺伝子変換コーン
US6395966B1 (en) 1990-08-09 2002-05-28 Dekalb Genetics Corp. Fertile transgenic maize plants containing a gene encoding the pat protein
US5792921A (en) * 1992-02-14 1998-08-11 Londesborough; John Increasing the trehalose content of organisms by transforming them with combinations of the structural genes for trehalose synthase
US6130368A (en) * 1992-02-14 2000-10-10 Btg International Ltd Transgenic plants producing trehalose
FI943133A0 (fi) * 1994-06-29 1994-06-29 Alko Ab Oy Transgena vaexter
US6133034A (en) * 1992-05-27 2000-10-17 Calgene, Inc. Methods and compositions related to the production of trehalose
EP0711353B1 (de) * 1993-06-30 2004-12-08 Syngenta Mogen B.V. Herstellung von trehalose in pflanzen
WO1995006126A1 (en) * 1993-08-24 1995-03-02 Mogen International N.V. Production of trehalose in plants
RU2143496C1 (ru) * 1993-06-30 1999-12-27 Моген Интернэшнл Н.В. Продуцирование трегалозы в растениях
US6281411B1 (en) 1993-08-25 2001-08-28 Dekalb Genetics Corporation Transgenic monocots plants with increased glycine-betaine content
US6326527B1 (en) 1993-08-25 2001-12-04 Dekalb Genetics Corporation Method for altering the nutritional content of plant seed
US6118047A (en) 1993-08-25 2000-09-12 Dekalb Genetic Corporation Anthranilate synthase gene and method of use thereof for conferring tryptophan overproduction
KR100468307B1 (ko) * 1994-06-29 2005-12-26 비티지 인터내셔널 리미티드 트레할로스를생성하는유전자도입식물
DE4444460A1 (de) * 1994-11-29 1996-05-30 Inst Genbiologische Forschung Verfahren zur Steigerung des Ertrags sowie zur Veränderung des Blühverhaltens bei Pflanzen
IL116564A0 (en) * 1995-01-04 1996-03-31 Mogen Int Process for producing trehalose in plants
EP0784095A3 (de) 1996-01-12 1997-12-29 Mogen International N.V. Erhöhte Trehalose Akkumulation in Pflanzen
IN1997CH00924A (en) 1996-05-03 2005-03-04 Syngenta Mogen Bv Regulating metabolism by modifying the level of trehalose-6-phosphate
MX205414B (es) * 1996-05-08 2001-12-07 Univ Mexico Nacional Autonoma Metodo para incrementar de trehalosa de los organismos por medio de su transformacion con el adnc de la trehalosa-6-fosfato sintasa/fosfatasa de selaginella lepidophylla.
ES2110918B1 (es) * 1996-07-04 1998-08-01 Univ Poltecnica De Valencia Obtencion de plantas tolerantes al estres osmotico mediante manipulacion genetica del metabolismo de carbohidratos.
JPH10117771A (ja) 1996-10-23 1998-05-12 Natl Food Res Inst 冷凍生地耐性実用パン酵母
GB9703681D0 (en) * 1997-02-21 1997-04-09 Gene Shears Pty Ltd Protein complemention
ZA989782B (en) 1997-10-30 1999-05-04 Mogen Int Pre-and postharvest inhibition of remobilisation of storage compounds
WO1999023225A1 (en) * 1997-10-30 1999-05-14 Mogen International N.V. Novel high-fermenting microorganisms
WO1999024558A2 (en) * 1997-10-30 1999-05-20 Mogen International N.V. Novel high-fermenting microorganisms
JP4278726B2 (ja) * 1997-12-08 2009-06-17 独立行政法人農業・食品産業技術総合研究機構 冷凍生地耐性および高糖生地耐性実用パン酵母
JP2002505875A (ja) 1998-03-11 2002-02-26 ノバルティス アクチエンゲゼルシャフト 植物中トレハロース生合成遺伝子の発現
EP1002867A1 (de) * 1998-10-15 2000-05-24 K.U. Leuven Research & Development Spezifische genetische Veränderung der Aktivität von Trehalose-6-phosphatsynthase und Expression in einer homologen und heterologen Umgebung
AU2005202773B8 (en) * 1998-10-15 2008-10-16 Vlaams Interuniversitair Instituut Voor Biotechnologie V.Z.W.(Vib) Specific genetic modification of the activity of trehalose-6-phosphate synthase and expression in a Homologous or heterologous environment
CH690127A5 (de) * 1999-02-11 2000-05-15 Rheinbiotech Gmbh Hitzeschock induzierter Promotor.
GB9919732D0 (en) * 1999-08-19 1999-10-20 Colaco Camilo Trehalose producing cells as vaccines
AU4507001A (en) * 1999-11-16 2001-06-25 Regents Of The University Of California, The Enhancing trehalose biosynthesis
US20090017161A1 (en) * 2006-02-28 2009-01-15 Suntory Limited Gene encoding protein having trehalose synthesis-promoting activity and use thereof
JP2013513394A (ja) * 2009-12-15 2013-04-22 ストラトリー・アーゲー 希薄水溶液から有機成分を回収するための方法
BR112021009161A2 (pt) * 2018-11-13 2021-08-31 Lallemand Hungary Liquidity Management Llc. Expressão combinada de enzimas de produção de trealose e degradação de trealose
KR102500338B1 (ko) * 2022-07-28 2023-02-16 에스피씨 주식회사 우수한 발효 특징을 가진 신규 제빵용 효모 사카로마이세스 세레비지애 spc y76h

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ATE133198T1 (de) * 1990-03-28 1996-02-15 Gist Brocades Nv Neue hefestämme mit erhöhtem trehalosegehalt, verfahren zur gewinnung solcher hefen und verwendung dieser hefen
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Also Published As

Publication number Publication date
FI943739A7 (fi) 1994-10-14
FI943739A0 (fi) 1994-08-12
NZ249133A (en) 1995-09-26
EP0635051B1 (de) 2004-06-23
JPH07503853A (ja) 1995-04-27
DE69333559D1 (de) 2004-07-29
CA2130082A1 (en) 1993-09-02
AU3500993A (en) 1993-09-13
AU677175B2 (en) 1997-04-17
WO1993017093A2 (en) 1993-09-02
US5422254A (en) 1995-06-06
HK1005834A1 (en) 1999-01-29
WO1993017093A3 (en) 1993-09-30
EP0635051A1 (de) 1995-01-25

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