|
NZ199722A
(en)
*
|
1981-02-25 |
1985-12-13 |
Genentech Inc |
Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
|
|
JPS58146281A
(ja)
*
|
1981-10-19 |
1983-08-31 |
Suntory Ltd |
酵母細胞の形質転換法
|
|
US4775622A
(en)
*
|
1982-03-08 |
1988-10-04 |
Genentech, Inc. |
Expression, processing and secretion of heterologous protein by yeast
|
|
EP0096910B1
(en)
*
|
1982-05-19 |
1989-04-19 |
Unilever N.V. |
Yeast of the genus kluyveromyces modified for the expression of preprothaumatin or its various allelic and modified forms or their maturation forms
|
|
GB2125047B
(en)
*
|
1982-08-09 |
1986-02-19 |
Ciba Geigy Ag |
Yeast hybrid vectors and their use for the production of polypeptides
|
|
AU577259B2
(en)
*
|
1982-08-13 |
1988-09-22 |
Zymogenetics Inc. |
Glycolytic promters for regulated protein expression protease inhibitor
|
|
JPS5931799A
(ja)
*
|
1982-08-16 |
1984-02-20 |
Science & Tech Agency |
B型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
|
|
US4977092A
(en)
*
|
1985-06-26 |
1990-12-11 |
Amgen |
Expression of exogenous polypeptides and polypeptide products including hepatitis B surface antigen in yeast cells
|
|
DE3382547D1
(de)
*
|
1983-01-12 |
1992-05-27 |
Chiron Corp |
Sekretorische expression in eukaryoten.
|
|
US5089398A
(en)
*
|
1983-02-22 |
1992-02-18 |
Chiron Corporation |
Enhanced yeast transcription employing hybrid GAPDH promoter region constructs
|
|
US4876197A
(en)
*
|
1983-02-22 |
1989-10-24 |
Chiron Corporation |
Eukaryotic regulatable transcription
|
|
JPS60501140A
(ja)
*
|
1983-04-22 |
1985-07-25 |
アムジエン |
酵母による外因性ポリペプチドの分泌
|
|
EP0143821A1
(fr)
*
|
1983-05-19 |
1985-06-12 |
Transgene S.A. |
Production de la catechol 2,3-oxygenase par des levures, plasmide pour sa mise en oeuvre et application
|
|
FR2561662B2
(fr)
*
|
1984-03-22 |
1986-08-22 |
Transgene Sa |
Bloc d'expression de la catechol 2,3-oxygenase dans les levures et souche marquee par ce bloc d'expression
|
|
EP0129268B1
(en)
*
|
1983-05-19 |
1989-10-04 |
Unilever N.V. |
Improvements in the expression of newly introduced genes in yeast cells
|
|
GB8314961D0
(en)
*
|
1983-05-31 |
1983-07-06 |
Kingsman A J |
Dna sequence
|
|
US4870008A
(en)
*
|
1983-08-12 |
1989-09-26 |
Chiron Corporation |
Secretory expression in eukaryotes
|
|
GB8325043D0
(en)
*
|
1983-09-19 |
1983-10-19 |
Kingsman A J |
Vector
|
|
FR2552776B1
(fr)
*
|
1983-10-03 |
1986-05-09 |
Transgene Sa |
Vecteurs d'expression d'une proteine antigenique de la rage dans les cellules eucaryotes et leur application a la preparation d'un vaccin
|
|
WO1985001516A1
(fr)
*
|
1983-10-03 |
1985-04-11 |
Transgene S.A. |
Vecteurs d'expression d'une proteine antigenique de la rage dans les cellules eucaryotes et leur application a la preparation d'un vaccin
|
|
FR2562090B2
(fr)
*
|
1984-03-27 |
1988-04-08 |
Transgene Sa |
Proteine antigenique de la rage glycosylee
|
|
GB8334261D0
(en)
*
|
1983-12-22 |
1984-02-01 |
Bass Plc |
Fermentation processes
|
|
AU587176B2
(en)
*
|
1984-02-14 |
1989-08-10 |
Mycogen Plant Science, Inc. |
Transfer vector
|
|
FR2559782B1
(fr)
*
|
1984-02-16 |
1986-07-18 |
Transgene Sa |
Vecteur d'expression dans les levures de l'interleukine-2, levures transformees et procede de preparation de l'interleukine-2
|
|
FI841500A0
(fi)
*
|
1984-04-13 |
1984-04-13 |
Valtion Teknillinen |
Foerfarande foer uppbygnande av cellulolytiska jaeststammar.
|
|
FR2564106B1
(fr)
*
|
1984-05-09 |
1988-04-22 |
Transgene Sa |
Vecteurs d'expression du facteur ix, cellules transformees par ces vecteurs et procede de preparation du facteur ix.
|
|
US4880734A
(en)
*
|
1984-05-11 |
1989-11-14 |
Chiron Corporation |
Eukaryotic regulatable transcription
|
|
DK58285D0
(da)
*
|
1984-05-30 |
1985-02-08 |
Novo Industri As |
Peptider samt fremstilling og anvendelse deraf
|
|
SU1364343A1
(ru)
*
|
1984-07-13 |
1988-01-07 |
Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов |
Способ получени человеческого лейкоцитарного интерферона альфа-2
|
|
US4762786A
(en)
*
|
1984-09-27 |
1988-08-09 |
Eli Lilly And Company |
Vectors and conditions which allow genetic transformation of cephalosporium
|
|
US4855231A
(en)
*
|
1984-10-30 |
1989-08-08 |
Phillips Petroleum Company |
Regulatory region for heterologous gene expression in yeast
|
|
US4885242A
(en)
*
|
1984-10-30 |
1989-12-05 |
Phillips Petroleum Company |
Genes from pichia histidine pathway and uses thereof
|
|
CA1341482C
(en)
|
1984-10-31 |
2005-05-10 |
Paul A. Luciw |
Process for preparing fragments of aids-associated retroviruses
|
|
US7285271B1
(en)
|
1984-10-31 |
2007-10-23 |
Novartis Vaccines And Diagnostics, Inc. |
Antigenic composition comprising an HIV gag or env polypeptide
|
|
US7273695B1
(en)
|
1984-10-31 |
2007-09-25 |
Novartis Vaccines And Diagnostics, Inc. |
HIV immunoassays using synthetic envelope polypeptides
|
|
JPS61268184A
(ja)
*
|
1984-11-05 |
1986-11-27 |
Green Cross Corp:The |
組換えプラスミド及び当該プラスミドによる形質転換株
|
|
CA1280080C
(en)
*
|
1984-12-06 |
1991-02-12 |
Jacques Oberto |
Promoters for the expression of foreign genes in yeast, plasmids comprising them, and uses thereof for the production of polypeptides
|
|
JPS61141890A
(ja)
*
|
1984-12-15 |
1986-06-28 |
Suntory Ltd |
アルコ−ルの製造法
|
|
GB8513645D0
(en)
*
|
1985-05-30 |
1985-07-03 |
Kingsman A J |
Expression vector
|
|
US4882282A
(en)
*
|
1985-08-16 |
1989-11-21 |
Immunex Corporation |
DNA sequences encoding bovine interleukin-2
|
|
EP0240550A4
(en)
*
|
1985-09-26 |
1989-09-19 |
Genetics Inst |
Pulmonary surfactant proteins.
|
|
US5104795A
(en)
*
|
1985-11-13 |
1992-04-14 |
Zoma Corporation |
Shortened phosphoglycerate kinase promoter
|
|
EP0245479B1
(en)
*
|
1985-11-13 |
1993-02-17 |
Xoma Corporation |
Shortened phosphoglycerate kinase promoter
|
|
GB8620926D0
(en)
*
|
1986-08-29 |
1986-10-08 |
Delta Biotechnology Ltd |
Yeast promoter
|
|
DE3635867A1
(de)
*
|
1986-10-22 |
1988-05-11 |
Boehringer Ingelheim Int |
Neue hefeexpressionsvektoren fuer ifn-omega, verfahren zu ihrer herstellung und deren verwendung
|
|
US5378603A
(en)
*
|
1987-03-30 |
1995-01-03 |
Board Of Regents, The University Of Texas System |
Method and composition for identifying substances which activate transcription of the LDL receptor gene
|
|
JPS6463395A
(en)
|
1987-05-04 |
1989-03-09 |
Oncogen |
Oncostatin m and novel composition having antitumor activity
|
|
US4966841A
(en)
*
|
1987-05-22 |
1990-10-30 |
The Board Of Regents Of The University Of Washington |
Enhanced vector production and expression of recombinant DNA products
|
|
ES2093606T3
(es)
|
1987-06-23 |
1997-01-01 |
Univ Leland Stanford Junior |
Gen del receptor de celulas t localizado en el locus alfa y estructuras artificiales de adn.
|
|
WO1988010308A1
(en)
*
|
1987-06-24 |
1988-12-29 |
Whitehead Institute For Biomedical Research |
Pheromone-inducible yeast promoter
|
|
US5063154A
(en)
*
|
1987-06-24 |
1991-11-05 |
Whitehead Institute For Biomedical Research |
Pheromone - inducible yeast promoter
|
|
US5591603A
(en)
*
|
1987-08-28 |
1997-01-07 |
Novo Nordisk A/S |
Process for preparing aprotinin and aprotinin analogs in yeast cells
|
|
US5049493A
(en)
*
|
1987-10-23 |
1991-09-17 |
California Institute Of Technology |
Enhancement of cell growth by expression of a cloned hemoglobin gene
|
|
US7442525B1
(en)
|
1987-12-24 |
2008-10-28 |
Novartis Vaccines And Diagnostics, Inc. |
Method for expressing HIV polypeptides
|
|
FR2628750B1
(fr)
*
|
1988-03-21 |
1991-11-08 |
Pasteur Institut |
Vecteur modifie par une sequence codant pour une sequence d'acides amines contenue dans une proteine de mammifere ayant une activite biologique de recepteur membranaire
|
|
US5258502A
(en)
*
|
1989-01-30 |
1993-11-02 |
Massachusetts Institute Of Technology |
Immobilization and purification of fusion proteins using chitin-binding ability
|
|
US6172039B1
(en)
|
1990-04-16 |
2001-01-09 |
Apex Bioscience, Inc. |
Expression of recombinant hemoglobin and hemoglobin variants in yeast
|
|
US5206153A
(en)
*
|
1990-06-27 |
1993-04-27 |
Snow Brand Milk Products Co., Ltd. |
Method of producing human α-fetoprotein and product produced thereby
|
|
ES2157197T3
(es)
*
|
1990-09-13 |
2001-08-16 |
Univ Duke |
Expresion de receptores acoplados a una proteina g en levadura.
|
|
US6027722A
(en)
*
|
1990-10-25 |
2000-02-22 |
Nature Technology Corporation |
Vectors for gene transfer
|
|
ES2121794T3
(es)
*
|
1990-10-25 |
1998-12-16 |
Clague Pitman Hodgson |
Procedimiento de transferencia de genes por medio de retrotransposones.
|
|
SG84484A1
(en)
*
|
1991-02-25 |
2001-11-20 |
Ciba Geigy Ag |
Improved yeast vectors
|
|
US20100267023A1
(en)
*
|
1992-09-24 |
2010-10-21 |
Keygene N.V. |
Selective restriction fragment amplification: fingerprinting
|
|
US5422254A
(en)
*
|
1992-02-14 |
1995-06-06 |
Oy Alko Ab |
Method to increase the trehalose content of organisms by transforming them with the structural genes for the short and long chains of yeast trehalose synthase
|
|
EP0688358A4
(en)
|
1993-03-12 |
1997-10-01 |
Univ Creighton |
IMPROVED VECTORS FOR GENTHERAPY
|
|
US20030190753A1
(en)
*
|
1995-11-09 |
2003-10-09 |
Nature Technology Corporation |
Vectors for gene transfer
|
|
UA75316C2
(uk)
|
1996-10-16 |
2006-04-17 |
Займодженетікс, Інк. |
Гомологи з фактором росту фібробласта
|
|
US6017694A
(en)
*
|
1997-12-19 |
2000-01-25 |
American Cyanamid Company |
Methods of screening for modulators of respiratory syncytial virus matrix protein interaction
|
|
CZ20011026A3
(cs)
|
1998-09-23 |
2001-08-15 |
Zymogenetics, Inc. |
Izolovaný polynukleotid, expresní vektor, kultivovaná buňka, konstrukt DNA, způsob produkce proteinu, izolovaný polypeptid, způsob produkce protilátky, protilátka a způsob detekce
|
|
DE69939330D1
(de)
|
1998-12-07 |
2008-09-25 |
Zymogenetics Inc |
Wachstumsfaktor-homologe zvegf-3
|
|
US7833529B1
(en)
|
1999-01-07 |
2010-11-16 |
Zymogenetics, Inc. |
Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
|
|
CZ303272B6
(cs)
|
1999-01-07 |
2012-07-11 |
Zymogenetics, Inc. |
Farmaceutický prostredek obsahující fúzní protein, izolovaná molekula polynukleotidu, expresní vektor, kultivovaná bunka, zpusob prípravy polypeptidu a izolovaný polypeptid
|
|
UA84387C2
(ru)
|
1999-03-09 |
2008-10-27 |
Займодженетикс, Инк. |
Человеческий цитокин как лиганд зальфа рецептора и его применение
|
|
DE60034564T2
(de)
|
1999-07-07 |
2007-12-27 |
Zymogenetics, Inc., Seattle |
Menschlicher cytokinrezeptor
|
|
EP2194130A1
(en)
|
1999-12-23 |
2010-06-09 |
ZymoGenetics, L.L.C. |
Cytokine ZCYTO18
|
|
WO2001087933A2
(en)
|
2000-05-11 |
2001-11-22 |
Zymogenetics, Inc. |
Zsig33-like peptides
|
|
EP1325115B1
(en)
|
2000-06-26 |
2016-07-27 |
ZymoGenetics, Inc. |
Cytokine receptor zcytor17
|
|
ES2286128T3
(es)
|
2000-06-30 |
2007-12-01 |
Zymogenetics, Inc. |
Proteina zcyto21 tipo interferon.
|
|
EP1736545A3
(en)
|
2000-08-08 |
2007-03-28 |
ZymoGenetics, Inc. |
Soluble zcytor 11 cytokine receptors
|
|
AU2002238052A1
(en)
|
2001-02-20 |
2002-09-04 |
Zymogenetics, Inc. |
Antibodies that bind both bcma and taci
|
|
FR2821625B1
(fr)
*
|
2001-03-01 |
2003-05-16 |
Genodyssee |
Nouveaux polynucleotides comportant un polymorphisme de type snp fonctionnel dans la sequence nucleotidique du gene ifn-alpha-2 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques
|
|
FR2823220B1
(fr)
*
|
2001-04-04 |
2003-12-12 |
Genodyssee |
Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
|
|
PL403488A1
(pl)
|
2001-05-24 |
2013-07-08 |
Zymogenetics, Inc. |
Zastosowanie bialka fuzyjnego TACI-immunoglobulina, bialko fuzyjne, czasteczka kwasu nukleinowego kodujaca bialko fuzyjne, kompozycja farmaceutyczna i sposób wytwarzania bialka fuzyjnego TACI-immunoglobulina
|
|
US6645739B2
(en)
|
2001-07-26 |
2003-11-11 |
Phoenix Pharmacologies, Inc. |
Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
|
|
CA2457282C
(en)
|
2001-09-13 |
2015-01-13 |
California Institute Of Technology |
Method for expression of small antiviral rna molecules within a cell
|
|
EP1425400B1
(en)
|
2001-09-13 |
2016-11-02 |
California Institute Of Technology |
Method for producing transgenic animals
|
|
EP2130919A1
(en)
|
2001-11-05 |
2009-12-09 |
ZymoGenetics, Inc. |
IL-21 antagonists
|
|
WO2004003140A2
(en)
|
2002-01-18 |
2004-01-08 |
Zymogenetics, Inc. |
Cytokine receptor zcytor17 multimers
|
|
RU2490276C2
(ru)
|
2002-01-18 |
2013-08-20 |
Займоджинетикс, Инк. |
Новый лиганд рецептора цитокина zcytor17
|
|
CN1659274A
(zh)
|
2002-04-19 |
2005-08-24 |
津莫吉尼蒂克斯公司 |
细胞因子受体
|
|
JP4808157B2
(ja)
|
2003-08-07 |
2011-11-02 |
ザイモジェネティクス リミテッド ライアビリティ カンパニー |
Il−28およびil−29の均一な調製物
|
|
CA2558811A1
(en)
|
2004-03-08 |
2005-09-22 |
Zymogenetics, Inc. |
Dimeric fusion proteins and materials and methods for producing them
|
|
US7351689B2
(en)
|
2004-07-29 |
2008-04-01 |
Zymogenetics, Inc. |
Use of IL-28 and IL-29 to treat cancer and autoimmune disorders
|
|
EP1781784A2
(en)
|
2004-08-02 |
2007-05-09 |
BASF Plant Science GmbH |
Method for isolation of transcription termination sequences
|
|
WO2006086396A2
(en)
|
2005-02-08 |
2006-08-17 |
Zymogenetics, Inc. |
Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation
|
|
EP3683230A1
(en)
|
2005-05-12 |
2020-07-22 |
ZymoGenetics, Inc. |
Compositions and methods for modulating immune responses
|
|
US8808696B2
(en)
|
2005-08-09 |
2014-08-19 |
Ares Trading S.A. |
Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules
|
|
KR20080056714A
(ko)
*
|
2005-08-09 |
2008-06-23 |
지모제넥틱스, 인코포레이티드 |
TACI―Ig 융합 분자를 사용하여 B―세포 악성종양을치료하는 방법
|
|
WO2007134326A2
(en)
*
|
2006-05-15 |
2007-11-22 |
Ares Trading S.A. |
Methods for treating autoimmune diseases using a taci-ig fusion molecule
|
|
WO2008157263A2
(en)
|
2007-06-15 |
2008-12-24 |
Arkansas State University |
Methods of delivery of molecules to cells using a ricin subunit and compositions relating to same
|
|
CN101918437B
(zh)
|
2007-11-21 |
2013-08-14 |
罗斯基勒大学 |
具有冰结合活性的多肽
|
|
US20110027337A1
(en)
*
|
2007-12-21 |
2011-02-03 |
Ifxa A/S |
Protease inhibitor
|
|
KR101720760B1
(ko)
*
|
2008-01-25 |
2017-03-28 |
오르후스 우니베르시테트 |
Igfbp-4에 대한 papp-a 활성의 선택적 엑소사이트 억제
|
|
JP5425180B2
(ja)
|
2008-03-27 |
2014-02-26 |
ザイモジェネティクス, インコーポレイテッド |
PDGFRβおよびVEGF−Aを阻害するための組成物および方法
|
|
WO2009158696A1
(en)
|
2008-06-27 |
2009-12-30 |
Zymogenetics, Inc. |
SOLUBLE HYBRID Fcγ RECEPTORS AND RELATED METHODS
|
|
RU2422504C2
(ru)
*
|
2008-11-07 |
2011-06-27 |
Учреждение Российской академии наук Институт микробиологии им. С.Н. Виноградского РАН |
СПОСОБ ПОЛУЧЕНИЯ ЭКСПРЕССИОННОГО ПЛАЗМИДНОГО ВЕКТОРА, ОБЛАДАЮЩЕГО ПОВЫШЕННОЙ СТАБИЛЬНОСТЬЮ НАСЛЕДОВАНИЯ В КЛЕТКАХ Escherichia coli
|
|
EP2580238A1
(en)
|
2010-06-09 |
2013-04-17 |
Zymogenetics, Inc. |
Dimeric vstm3 fusion proteins and related compositions and methods
|
|
CA2862149C
(en)
|
2012-02-01 |
2022-07-26 |
Synthetic Genomics, Inc. |
Materials and methods for the synthesis of error-minimized nucleic acid molecules
|
|
WO2014202089A2
(en)
|
2013-06-18 |
2014-12-24 |
Roskilde Universitet |
Variants of anti-freeze polypeptides
|
|
CN107969127B
(zh)
|
2015-09-08 |
2022-09-06 |
赛瑞品股份有限公司 |
Apoa-1融合多肽及相关组合物和方法
|
|
HK1251480A1
(zh)
|
2015-09-21 |
2019-02-01 |
Aptevo Research And Development Llc |
Cd3结合多肽
|
|
WO2018136163A2
(en)
|
2016-12-09 |
2018-07-26 |
Theripion, Inc. |
Tandem apoa-1 fusion polypeptides
|
|
US11725060B2
(en)
|
2017-07-20 |
2023-08-15 |
Aptevo Reserch and Development LLC |
Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods
|
|
SG11202005692WA
(en)
|
2017-12-20 |
2020-07-29 |
Harbour Biomed Shanghai Co Ltd |
Antibodies binding ctla-4 and uses thereof
|
|
US10150801B1
(en)
|
2017-12-27 |
2018-12-11 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
WO2019132765A1
(en)
|
2017-12-27 |
2019-07-04 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
WO2021040610A1
(en)
|
2019-08-26 |
2021-03-04 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
US10675332B1
(en)
|
2019-08-26 |
2020-06-09 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
US20240293504A1
(en)
|
2020-06-22 |
2024-09-05 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and combinations for use in the treatment of cancer
|
|
EP4294916A2
(en)
|
2021-02-19 |
2023-12-27 |
Theripion, Inc. |
Dnase fusion polypeptides and related compositions and methods
|
|
CN120584137A
(zh)
|
2023-01-06 |
2025-09-02 |
阿帕特夫研究和发展有限公司 |
双特异性pd-l1和cd40结合分子以及其用途
|
|
WO2024259220A1
(en)
|
2023-06-15 |
2024-12-19 |
Theripion, Inc. |
Pon3 and evolved pon1 fusion polypeptides
|