ATE269977T1 - Bindungsbeschleunigungsverfahren zum nachweis von analyten - Google Patents

Bindungsbeschleunigungsverfahren zum nachweis von analyten

Info

Publication number
ATE269977T1
ATE269977T1 AT00978615T AT00978615T ATE269977T1 AT E269977 T1 ATE269977 T1 AT E269977T1 AT 00978615 T AT00978615 T AT 00978615T AT 00978615 T AT00978615 T AT 00978615T AT E269977 T1 ATE269977 T1 AT E269977T1
Authority
AT
Austria
Prior art keywords
acceleration method
detecting analytes
binding
etm
binding acceleration
Prior art date
Application number
AT00978615T
Other languages
English (en)
Inventor
Gary Blackburn
Jost G Vielmetter
Jon Faiz Kayyem
Original Assignee
Clinical Micro Sensors Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clinical Micro Sensors Inc filed Critical Clinical Micro Sensors Inc
Application granted granted Critical
Publication of ATE269977T1 publication Critical patent/ATE269977T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Materials Engineering (AREA)
  • Food Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Cell Biology (AREA)
  • Composite Materials (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT00978615T 1999-11-12 2000-11-13 Bindungsbeschleunigungsverfahren zum nachweis von analyten ATE269977T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44037199A 1999-11-12 1999-11-12
US17198199P 1999-12-23 1999-12-23
PCT/US2000/031233 WO2001035100A2 (en) 1999-11-12 2000-11-13 Binding acceleration techniques for the detection of analytes

Publications (1)

Publication Number Publication Date
ATE269977T1 true ATE269977T1 (de) 2004-07-15

Family

ID=26867628

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00978615T ATE269977T1 (de) 1999-11-12 2000-11-13 Bindungsbeschleunigungsverfahren zum nachweis von analyten

Country Status (8)

Country Link
EP (1) EP1254372B1 (de)
JP (1) JP3548159B2 (de)
AT (1) ATE269977T1 (de)
AU (1) AU778556B2 (de)
CA (1) CA2388780C (de)
DE (1) DE60011821T2 (de)
ES (1) ES2225264T3 (de)
WO (1) WO2001035100A2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071699A (en) 1996-06-07 2000-06-06 California Institute Of Technology Nucleic acid mediated electron transfer
US6761816B1 (en) 1998-06-23 2004-07-13 Clinical Micro Systems, Inc. Printed circuit boards with monolayers and capture ligands
WO2000024941A1 (en) 1998-10-27 2000-05-04 Clinical Micro Sensors, Inc. Detection of target analytes using particles and electrodes
US6942771B1 (en) 1999-04-21 2005-09-13 Clinical Micro Sensors, Inc. Microfluidic systems in the electrochemical detection of target analytes
US7312087B2 (en) 2000-01-11 2007-12-25 Clinical Micro Sensors, Inc. Devices and methods for biochip multiplexing
US6361958B1 (en) 1999-11-12 2002-03-26 Motorola, Inc. Biochannel assay for hybridization with biomaterial
US6602400B1 (en) 2000-06-15 2003-08-05 Motorola, Inc. Method for enhanced bio-conjugation events
DE10049901C2 (de) * 2000-10-10 2003-01-02 Aventis Res & Tech Gmbh & Co Vorrichtung und Verfahren zur elektrisch beschleunigten Immobilisierung und zur Detektion von Molekülen
WO2002031482A2 (de) * 2000-10-10 2002-04-18 Nanogen, Inc. Vorrichtung und verfahren zur elektrisch beschleunigten immobilisierung von molekülen
US7198754B2 (en) 2001-08-31 2007-04-03 Kabushiki Kaisha Toshiba Biological material detection element, biological material detection method and apparatus, charged material moving apparatus
CA2468743A1 (en) * 2001-11-30 2003-06-12 Northwestern University Direct write nanolithographic deposition of nucleic acids from nanoscopic tips
CA2474530A1 (en) * 2002-02-07 2003-08-14 Eastern Virginia Medical School Of The Medical College Of Hampton Roads Diagnostic microarray and method of use thereof
TWI221523B (en) 2002-05-21 2004-10-01 Sony Corp Bioassay method, bioassay device, and bioassay substrate
WO2004101785A1 (ja) * 2003-05-13 2004-11-25 Jsr Corporation 目的遺伝子の抽出方法およびプローブdna結合粒子
JP4464664B2 (ja) * 2003-06-13 2010-05-19 独立行政法人理化学研究所 生体分子マイクロアレイ用基板、生体分子マイクロアレイ、相互作用促進用装置および方法、ならびに、相互作用の検出方法
US8455088B2 (en) 2005-12-23 2013-06-04 Boston Scientific Scimed, Inc. Spun nanofiber, medical devices, and methods
US7470466B2 (en) 2005-12-23 2008-12-30 Boston Scientific Scimed, Inc. Nanoparticle structures and composite materials comprising a silicon-containing compound having a chemical linker that forms a non-covalent bond with a polymer
US20070151856A1 (en) * 2005-12-29 2007-07-05 Fazzio R S Fluidic device having contiguous conductive layer over interior and exterior surfaces thereof
JP2007267644A (ja) * 2006-03-30 2007-10-18 Toshiba Corp 単位塩基の繰り返し回数の測定方法
WO2008020364A2 (en) * 2006-08-14 2008-02-21 Koninklijke Philips Electronics N. V. Biochemical sensor device
EP2136716A2 (de) * 2007-03-14 2009-12-30 Ogeno Gmbh Biopsievorrichtung zur in-vivo-anreicherung von geweben, zellen oder analyten
JP6337470B2 (ja) * 2012-06-20 2018-06-06 東レ株式会社 核酸の検出方法および核酸検出キット
US10114015B2 (en) 2013-03-13 2018-10-30 Meso Scale Technologies, Llc. Assay methods
CN117288934A (zh) 2013-03-13 2023-12-26 中尺度技术有限责任公司 改进的测定方法
US9587268B2 (en) 2014-01-29 2017-03-07 Agilent Technologies Inc. Fast hybridization for next generation sequencing target enrichment
KR102757668B1 (ko) 2014-05-15 2025-01-21 메소 스케일 테크놀러지즈, 엘엘시 개선된 분석 방법
US11446663B2 (en) 2018-01-26 2022-09-20 Aincobio Llc Method and apparatus for isolating and detecting biological and other particles
CN120098057A (zh) 2019-03-01 2025-06-06 中尺度技术有限责任公司 用于免疫方法的被电化学发光标记的探针、使用这类探针的方法和包含这类探针的试剂盒
WO2022022480A1 (zh) * 2020-07-27 2022-02-03 南京金斯瑞生物科技有限公司 一种半导体芯片的表面连接体及其制备方法和应用
AU2022304570A1 (en) 2021-06-28 2024-01-18 Meso Scale Technologies, Llc. Methods, compositions, and kits for assay signal amplification
CA3229708A1 (en) * 2021-08-16 2023-02-23 Diagmetrics, Inc. Diagnostic platform for testing exhaled breath condensate and universal biosensor
CN115895279B (zh) * 2022-11-24 2023-07-21 西北大学 一种SPAN/MOFs@Luminol发光材料及其制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4787963A (en) * 1987-05-04 1988-11-29 Syntro Corporation Method and means for annealing complementary nucleic acid molecules at an accelerated rate
US6017696A (en) * 1993-11-01 2000-01-25 Nanogen, Inc. Methods for electronic stringency control for molecular biological analysis and diagnostics
US6051380A (en) * 1993-11-01 2000-04-18 Nanogen, Inc. Methods and procedures for molecular biological analysis and diagnostics
US5632957A (en) * 1993-11-01 1997-05-27 Nanogen Molecular biological diagnostic systems including electrodes
AU735440B2 (en) * 1996-02-09 2001-07-05 Cornell Research Foundation Inc. Detection of nucleic acid sequence differences using the ligase detection reaction with addressable arrays
DE69835516D1 (de) * 1997-05-16 2006-09-21 Exact Sciences Corp Elektrophoretische analyse von molekülen mit immobilisierten sonden
EP1051517A2 (de) * 1998-01-27 2000-11-15 Clinical Micro Sensors, Inc. Amplifizierung von nukleinsäuren mit elektronischer erkennung
CA2327525A1 (en) * 1998-05-06 1999-11-11 Cynthia Bamdad Electronic detection of nucleic acids using monolayers
US6290839B1 (en) * 1998-06-23 2001-09-18 Clinical Micro Sensors, Inc. Systems for electrophoretic transport and detection of analytes

Also Published As

Publication number Publication date
JP2003514227A (ja) 2003-04-15
CA2388780A1 (en) 2001-05-17
DE60011821D1 (de) 2004-07-29
DE60011821T2 (de) 2005-07-07
JP3548159B2 (ja) 2004-07-28
EP1254372B1 (de) 2004-06-23
CA2388780C (en) 2006-06-06
AU1606301A (en) 2001-06-06
WO2001035100A2 (en) 2001-05-17
AU778556B2 (en) 2004-12-09
WO2001035100A3 (en) 2002-01-03
WO2001035100A9 (en) 2002-07-04
EP1254372A2 (de) 2002-11-06
ES2225264T3 (es) 2005-03-16

Similar Documents

Publication Publication Date Title
DE60011821D1 (de) Bindungsbeschleunigungsverfahren zum nachweis von analyten
WO1999067425A3 (en) Binding acceleration techniques for the detection of analytes
IL124322A0 (en) Detection of an entity in a sample
ATE498838T1 (de) Elektronische verfahren und vorrichtung zum nachweis von analyten
DE50003766D1 (de) Verfahren und vorrichtung zum nachweis und zur quantifizierung von biomolekülen
WO2003073817A3 (en) Rapid and sensitive detection of cells and viruses
EP1318399A3 (de) Passive Probefeststellung zum Beginn einer Analyse
ATE410684T1 (de) Molekular-modifikations-assays
DE60233142D1 (de) Verfahren und reagentien zum nachweis von endotoxin
IS6333A (is) DNA-röðunaraðferð
CA2217074A1 (en) Process for detecting target nucleic acid, process for quantifying the same, and pyrylium compound for chemiluminescence analysis
EA200500356A1 (ru) Способы обнаружения амниотической жидкости во влагалищном секрете и устройства для реализации указанных способов
ATE330704T1 (de) Vorrichtung zur probennahme von flüssigen proben
WO2002004670A3 (en) Improved capture and detection of target nucleic acid in dipstick assays
DK1246945T3 (da) Fremgangsmåde til identifikation af en mærkning anbragt på et fast legeme
ATE365324T1 (de) Nachweis durch serrs in mikrofluidischer umgebung
ATE513058T1 (de) Verdrängungsassay zur detektion von nukleinsäureoligomer-hybridisierungsereignissen
ATE232981T1 (de) Differenziertes timingsverfahren zum nachweiss multiple analyte in eine testprobe
NO20052553L (no) Cobalaminanalyse.
WO2003014695A3 (de) Biosensor und verfahren zum erfassen von makromolekularen biopolymeren mittels mindestens einer einheit zum immobilisieren von makromolekularen biopolymeren
DE60129020D1 (de) Vorrichtung und verfahren zum molekularen nachweis
AU1705801A (en) Dynamic determination of analytes
DE60127941D1 (de) Versuchsaufbau zum messen von kobalamin und folsäure
ATE258684T1 (de) Vorrichtung zur prozessierung von analyten an festphasen
ATE360819T1 (de) Verfahren zum nachweis von analyten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties