ATE365324T1 - Nachweis durch serrs in mikrofluidischer umgebung - Google Patents

Nachweis durch serrs in mikrofluidischer umgebung

Info

Publication number
ATE365324T1
ATE365324T1 AT02772626T AT02772626T ATE365324T1 AT E365324 T1 ATE365324 T1 AT E365324T1 AT 02772626 T AT02772626 T AT 02772626T AT 02772626 T AT02772626 T AT 02772626T AT E365324 T1 ATE365324 T1 AT E365324T1
Authority
AT
Austria
Prior art keywords
serrs
detection
microfluidic
ser
detecting
Prior art date
Application number
AT02772626T
Other languages
English (en)
Inventor
William Smith
Duncan Graham
Jonathan Mark Cooper
Ruth Keir
Eishi Igata
Original Assignee
Univ Strathclyde
Univ Glasgow
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Strathclyde, Univ Glasgow filed Critical Univ Strathclyde
Application granted granted Critical
Publication of ATE365324T1 publication Critical patent/ATE365324T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
    • B01F25/423—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path by means of elements placed in the receptacle for moving or guiding the components
    • B01F25/4231—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path by means of elements placed in the receptacle for moving or guiding the components using baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N21/658—Raman scattering enhancement Raman, e.g. surface plasmons
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0654—Lenses; Optical fibres
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0346—Capillary cells; Microcells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/651—Cuvettes therefore

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Carbon And Carbon Compounds (AREA)
AT02772626T 2001-11-02 2002-11-04 Nachweis durch serrs in mikrofluidischer umgebung ATE365324T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0126319.3A GB0126319D0 (en) 2001-11-02 2001-11-02 Microfluidic serrs detection

Publications (1)

Publication Number Publication Date
ATE365324T1 true ATE365324T1 (de) 2007-07-15

Family

ID=9925010

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02772626T ATE365324T1 (de) 2001-11-02 2002-11-04 Nachweis durch serrs in mikrofluidischer umgebung

Country Status (6)

Country Link
EP (1) EP1440317B1 (de)
JP (1) JP2005507500A (de)
AT (1) ATE365324T1 (de)
DE (1) DE60220815T2 (de)
GB (1) GB0126319D0 (de)
WO (1) WO2003038436A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005108571A1 (ja) * 2004-05-07 2005-11-17 Konica Minolta Medical & Graphic, Inc. 検査用マイクロリアクタおよび遺伝子検査装置ならびに遺伝子検査方法
WO2006010367A2 (en) 2004-07-26 2006-02-02 Danmarks Tekniske Universitet On-chip spectroscopy
WO2007021820A2 (en) 2005-08-11 2007-02-22 Eksigent Technologies, Llc Methods for measuring biochemical reactions
US8101403B2 (en) * 2006-10-04 2012-01-24 University Of Washington Method and device for rapid parallel microfluidic molecular affinity assays
GB0621050D0 (en) 2006-10-23 2006-11-29 Univ Strathclyde Functionalised polymers for labelling metal surfaces
JP5551355B2 (ja) * 2008-12-04 2014-07-16 川崎重工業株式会社 細胞カップリングモジュール、細胞カップリング装置及び細胞カップリング方法
DE102011016059B4 (de) 2011-04-01 2019-02-21 Friedrich-Schiller-Universität Jena Verfahren zur Korrektur von Raman-spektroskopischen Daten in einem Mehrphasensystem
JP6410290B2 (ja) * 2014-04-24 2018-10-24 公立大学法人兵庫県立大学 表面増強ラマン測定方法および表面増強ラマン測定装置
JP6536931B2 (ja) * 2014-11-18 2019-07-03 公立大学法人兵庫県立大学 表面増強ラマン測定方法および表面増強ラマン測定装置
EP3234557A1 (de) * 2014-12-16 2017-10-25 Medcom Advance, S.A. Analysevorrichtung, analyseeinrichtung zur identifizierung von analyten in flüssigkeiten und verwendung der analysevorrichtung
PH12022550104A1 (en) * 2019-07-15 2022-11-21 Sicpa Holding Sa Method for manufacturing surface enhanced raman spectroscopy tags
DE102021107229A1 (de) 2021-03-23 2022-09-29 Robert Bosch Gesellschaft mit beschränkter Haftung Online- oder In-situ-Messeinrichtung für eine Konzentrationsmessung eines Gases
KR102727404B1 (ko) * 2022-01-05 2024-11-08 ㈜피코파운드리 표면플라즈몬 공명에 기반하는 표면증강라만산란 기판 및 그 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6025202A (en) * 1995-02-09 2000-02-15 The Penn State Research Foundation Self-assembled metal colloid monolayers and detection methods therewith
WO1999018438A1 (en) * 1997-10-02 1999-04-15 Aclara Biosciences, Inc. Capillary assays involving separation of free and bound species
GB9810865D0 (en) * 1998-05-20 1998-07-22 Zeneca Ltd Nucleic acid sequence identification
AU1438701A (en) * 1999-10-27 2001-05-08 Caliper Technologies Corporation Pressure induced reagent introduction and electrophoretic separation
JP3316485B2 (ja) * 1999-11-17 2002-08-19 三菱重工業株式会社 ダイオキシン類分析方法及び装置
GB0008618D0 (en) * 2000-04-08 2000-05-31 Univ Strathclyde Analyte detection & apparatus therefor

Also Published As

Publication number Publication date
GB0126319D0 (en) 2002-01-02
EP1440317B1 (de) 2007-06-20
JP2005507500A (ja) 2005-03-17
DE60220815D1 (de) 2007-08-02
WO2003038436A2 (en) 2003-05-08
DE60220815T2 (de) 2008-03-06
EP1440317A2 (de) 2004-07-28
WO2003038436A3 (en) 2004-03-11

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