ATE270286T1 - Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung - Google Patents

Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung

Info

Publication number: ATE270286T1
Authority: AT; Austria
Prior art keywords: chain; alkyl; present; compound; aryl
Prior art date: 1997-07-25

Application number

AT98935844T

Other languages

English (en)

Inventor

Michael R Boyd

Tawnya C Mckee

John H Ii Cardellina

John A Beutler

Karen Erickson

Deborah Galinis

Lewis Pannell

Original Assignee

Us Gov Health & Human Serv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-07-25

Filing date

1998-07-23

Publication date

2004-07-15

1998-07-23 Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv

2004-07-15 Application granted granted Critical

2004-07-15 Publication of ATE270286T1 publication Critical patent/ATE270286T1/de

Links

150000002596 lactones Chemical class 0.000 title abstract 2
239000000203 mixture Substances 0.000 title 1
125000003118 aryl group Chemical group 0.000 abstract 5
150000001875 compounds Chemical class 0.000 abstract 4
125000004429 atom Chemical group 0.000 abstract 3
-1 oxime methyl ether Chemical class 0.000 abstract 3
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 2
229920006395 saturated elastomer Polymers 0.000 abstract 2
125000004417 unsaturated alkyl group Chemical group 0.000 abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
201000011510 cancer Diseases 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
150000002923 oximes Chemical class 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000001424 substituent group Chemical group 0.000 abstract 1
125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Pyrane Compounds (AREA)
Medicinal Preparation (AREA)

AT98935844T 1997-07-25 1998-07-23 Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung ATE270286T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US5378497P	1997-07-25	1997-07-25
PCT/US1998/015011 WO1999005136A1 (en)	1997-07-25	1998-07-23	Macrocyclic lactones, compositions, and methods of use

Publications (1)

Publication Number	Publication Date
ATE270286T1 true ATE270286T1 (de)	2004-07-15

Family

ID=21986519

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98935844T ATE270286T1 (de)	1997-07-25	1998-07-23	Macrozyklische laktone, zusammensetzungen und verfahren zur verwendung

Country Status (8)

Country	Link
US (1)	US6353019B1 (de)
EP (1)	EP1000053B1 (de)
JP (1)	JP2001510838A (de)
AT (1)	ATE270286T1 (de)
AU (1)	AU740668B2 (de)
CA (1)	CA2297198C (de)
DE (1)	DE69824855T2 (de)
WO (1)	WO1999005136A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7381744B1 (en) *	1999-03-05	2008-06-03	The United States Of America As Represented By The Department Of Health And Human Services	Method of treating osteoporosis comprising vacuolar-type (H+)-ATPase-inhibiting compounds
US7144918B2 (en) *	2000-07-24	2006-12-05	The United States Of America As Represented By The Department Of Health And Human Services	Biologically active macrolides, compositions, and uses thereof
AU7815201A (en)	2000-08-04	2002-02-18	Univ Texas	Synthetic salicylihalamides, apicularens and derivatives thereof
US6734209B2 (en)	2001-08-03	2004-05-11	Board Of Regents The University Of Texas System	Synthetic salicylihalamides, apicularens and derivatives thereof
EP1944307A3 (de)	2000-08-04	2008-07-30	Board of Regents, The University of Texas System	Synthetische Salicylihalamide, Apicularene und Derivate davon
US20030064542A1 (en) *	2001-10-02	2003-04-03	Corisis David J.	Methods of packaging an integrated circuit
AR045799A1 (es) *	2003-09-24	2005-11-16	Glaxo Group Ltd	Compuesto 6- oxo-2,5- dioxabiciclico y su uso para preparar una composicion farmaceutica
WO2015079009A1 (en) *	2013-11-28	2015-06-04	Universiteit Gent	Peloruside analogs

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU202248B (en) *	1988-06-14	1991-02-28	Chinoin Gyogyszer Es Vegyeszet	Process for producing pseudo-primicin, it's components and pharmaceutical compositions containing them as active components
US5430053A (en)	1994-04-19	1995-07-04	Arizona Board Of Regents Acting On Behalf Of Arizona State University	Isolation and structure of dictyostatin 1
US6207826B1 (en) *	1995-03-27	2001-03-27	Isis Pharmaceuticals, Inc.	Macrocyclic compounds having nitrogen-containing linkages
ES2149468T3 (es) *	1995-04-26	2000-11-01	Kyowa Hakko Kogyo Kk	Derivados de radicicol.
US6124453A (en) *	1995-07-04	2000-09-26	Novartis Ag	Macrolides
US6441186B1 (en)	1996-12-13	2002-08-27	The Scripps Research Institute	Epothilone analogs
JPH11180984A (ja) *	1997-12-22	1999-07-06	Kyowa Hakko Kogyo Co Ltd	クロラクトマイシン化合物
US6121257A (en) *	1999-03-31	2000-09-19	Abbott Laboratories	Sulfamate containing macrocyclic immunomodulators

1998
- 1998-07-23 CA CA2297198A patent/CA2297198C/en not_active Expired - Fee Related
- 1998-07-23 WO PCT/US1998/015011 patent/WO1999005136A1/en not_active Ceased
- 1998-07-23 DE DE69824855T patent/DE69824855T2/de not_active Expired - Lifetime
- 1998-07-23 AU AU85015/98A patent/AU740668B2/en not_active Ceased
- 1998-07-23 US US09/463,037 patent/US6353019B1/en not_active Expired - Lifetime
- 1998-07-23 JP JP2000504132A patent/JP2001510838A/ja active Pending
- 1998-07-23 AT AT98935844T patent/ATE270286T1/de not_active IP Right Cessation
- 1998-07-23 EP EP98935844A patent/EP1000053B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
EP1000053A1 (de)	2000-05-17
AU740668B2 (en)	2001-11-08
CA2297198C (en)	2010-06-22
DE69824855D1 (de)	2004-08-05
EP1000053B1 (de)	2004-06-30
WO1999005136A1 (en)	1999-02-04
DE69824855T2 (de)	2005-08-25
AU8501598A (en)	1999-02-16
JP2001510838A (ja)	2001-08-07
US6353019B1 (en)	2002-03-05
CA2297198A1 (en)	1999-02-04

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Legal Events

Date	Code	Title	Description
2004-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties