ATE270336T1 - Nisine - Google Patents

Nisine

Info

Publication number: ATE270336T1
Authority: AT; Austria
Prior art keywords: pct; organism; nisin; variant; sec
Prior art date: 1992-04-02

Application number

AT93907964T

Other languages

English (en)

Inventor

Michael John Gasson

Helen Mair Dodd

Original Assignee

Inst Of Food Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-02

Filing date

1993-04-01

Publication date

2004-07-15

1993-04-01 Application filed by Inst Of Food Res filed Critical Inst Of Food Res

2004-07-15 Application granted granted Critical

2004-07-15 Publication of ATE270336T1 publication Critical patent/ATE270336T1/de

Links

NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 abstract 4
108010053775 Nisin Proteins 0.000 abstract 4
239000004309 nisin Substances 0.000 abstract 4
235000010297 nisin Nutrition 0.000 abstract 4
108091026890 Coding region Proteins 0.000 abstract 1
101100510641 Lactococcus lactis subsp. lactis spaN gene Proteins 0.000 abstract 1
230000036039 immunity Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000004048 modification Effects 0.000 abstract 1
238000012986 modification Methods 0.000 abstract 1
IATSBFLNMNJNHI-XFCJPLPPSA-N prenisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C IATSBFLNMNJNHI-XFCJPLPPSA-N 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
230000001105 regulatory effect Effects 0.000 abstract 1
230000003248 secreting effect Effects 0.000 abstract 1
230000005945 translocation Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biotechnology (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Wood Science & Technology (AREA)
Biophysics (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Gastroenterology & Hepatology (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Medicinal Chemistry (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Insulated Gate Type Field-Effect Transistor (AREA)
Saccharide Compounds (AREA)

AT93907964T 1992-04-02 1993-04-01 Nisine ATE270336T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB929207267A GB9207267D0 (en)	1992-04-02	1992-04-02	Nisins
PCT/GB1993/000676 WO1993020213A1 (en)	1992-04-02	1993-04-01	Nisins

Publications (1)

Publication Number	Publication Date
ATE270336T1 true ATE270336T1 (de)	2004-07-15

Family

ID=10713353

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT93907964T ATE270336T1 (de)	1992-04-02	1993-04-01	Nisine

Country Status (7)

Country	Link
US (1)	US6100056A (de)
EP (1)	EP0633939B1 (de)
AT (1)	ATE270336T1 (de)
CA (1)	CA2133578A1 (de)
DE (1)	DE69333564T2 (de)
GB (2)	GB9207267D0 (de)
WO (1)	WO1993020213A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL9401935A (nl) *	1994-11-18	1996-07-01	Nl Zuivelonderzoek Inst	Werkwijze voor het regelen van de gen-expressie in melkzuurbacteriën.
EP0712935B1 (de) *	1994-11-18	2002-06-19	Stichting Nederlands Instituut Voor Zuivelonderzoek	Verfahren zur Kontrolle der Genexpression in Milchsäurebakterien
GB9423404D0 (en) *	1994-11-19	1995-01-11	Biotech & Biolog Scien Res	Production of nisin
US6861236B2 (en)	2002-05-24	2005-03-01	Applied Nanosystems B.V.	Export and modification of (poly)peptides in the lantibiotic way
CN106755220A (zh) *	2015-11-23	2017-05-31	武汉臻智生物科技有限公司	制备乳酸链球菌素的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE88215T1 (de) *	1983-09-06	1993-04-15	Microlife Technics	Abgeleitete nisin produzierende mikroorganismen, verfahren zur herstellung und verwendung und so erhaltene produkte.
US4990452A (en) *	1986-02-12	1991-02-05	Genex Corporation	Combining mutations for stabilization of subtilisin
US5218101A (en) *	1988-07-05	1993-06-08	The University Of Maryland	Leader sequence inducing a post-translational modification of polypeptides in bacteria, and gene therefor
EP0579730B1 (de) *	1991-04-11	2003-02-26	Stichting Nederlands Instituut Voor Zuivelonderzoek (Nizo)	Nisin a aehnliche lantibiotika, diese produzierende milchsaeurebakterien und deren herstellung

1992
- 1992-04-02 GB GB929207267A patent/GB9207267D0/en active Pending
1993
- 1993-04-01 CA CA002133578A patent/CA2133578A1/en not_active Abandoned
- 1993-04-01 AT AT93907964T patent/ATE270336T1/de not_active IP Right Cessation
- 1993-04-01 GB GB9419872A patent/GB2280442B/en not_active Expired - Fee Related
- 1993-04-01 US US08/773,731 patent/US6100056A/en not_active Expired - Fee Related
- 1993-04-01 EP EP93907964A patent/EP0633939B1/de not_active Expired - Lifetime
- 1993-04-01 WO PCT/GB1993/000676 patent/WO1993020213A1/en not_active Ceased
- 1993-04-01 DE DE69333564T patent/DE69333564T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
WO1993020213A1 (en)	1993-10-14
EP0633939A1 (de)	1995-01-18
DE69333564D1 (de)	2004-08-05
GB9207267D0 (en)	1992-05-13
EP0633939B1 (de)	2004-06-30
GB2280442A (en)	1995-02-01
CA2133578A1 (en)	1994-10-14
GB2280442B (en)	1995-10-18
DE69333564T2 (de)	2005-07-28
GB9419872D0 (en)	1994-11-23
US6100056A (en)	2000-08-08

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Legal Events

Date	Code	Title	Description
2004-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties