ATE292686T1 - Herstellung von nisin-varianten - Google Patents

Herstellung von nisin-varianten

Info

Publication number: ATE292686T1
Authority: AT; Austria
Prior art keywords: nisa gene; natural; production; variant; nisin
Prior art date: 1994-11-19

Application number

AT95937939T

Other languages

English (en)

Inventor

Michael John Gasson

Helen Mair Dodd

Original Assignee

Inst Of Food Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-19

Filing date

1995-11-20

Publication date

2005-04-15

1995-11-20 Application filed by Inst Of Food Res filed Critical Inst Of Food Res

2005-04-15 Application granted granted Critical

2005-04-15 Publication of ATE292686T1 publication Critical patent/ATE292686T1/de

Links

101100510641 Lactococcus lactis subsp. lactis spaN gene Proteins 0.000 abstract 6
230000002759 chromosomal effect Effects 0.000 abstract 2
NVNLLIYOARQCIX-MSHCCFNRSA-N Nisin Chemical compound N1C(=O)[C@@H](CC(C)C)NC(=O)C(=C)NC(=O)[C@@H]([C@H](C)CC)NC(=O)[C@@H](NC(=O)C(=C/C)/NC(=O)[C@H](N)[C@H](C)CC)CSC[C@@H]1C(=O)N[C@@H]1C(=O)N2CCC[C@@H]2C(=O)NCC(=O)N[C@@H](C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(NCC(=O)N[C@H](C)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCSC)C(=O)NCC(=O)N[C@H](CS[C@@H]2C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CCSC)C(=O)N[C@H](CCCCN)C(=O)N[C@@H]2C(N[C@H](C)C(=O)N[C@@H]3C(=O)N[C@@H](C(N[C@H](CC=4NC=NC=4)C(=O)N[C@H](CS[C@@H]3C)C(=O)N[C@H](CO)C(=O)N[C@H]([C@H](C)CC)C(=O)N[C@H](CC=3NC=NC=3)C(=O)N[C@H](C(C)C)C(=O)NC(=C)C(=O)N[C@H](CCCCN)C(O)=O)=O)CS[C@@H]2C)=O)=O)CS[C@@H]1C NVNLLIYOARQCIX-MSHCCFNRSA-N 0.000 abstract 1
108010053775 Nisin Proteins 0.000 abstract 1
239000004309 nisin Substances 0.000 abstract 1
235000010297 nisin Nutrition 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Biomedical Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Microbiology (AREA)
Gastroenterology & Hepatology (AREA)
Physics & Mathematics (AREA)
Medicinal Chemistry (AREA)
Plant Pathology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Saccharide Compounds (AREA)
Holo Graphy (AREA)
Peptides Or Proteins (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT95937939T 1994-11-19 1995-11-20 Herstellung von nisin-varianten ATE292686T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9423404A GB9423404D0 (en)	1994-11-19	1994-11-19	Production of nisin
PCT/GB1995/002699 WO1996016180A1 (en)	1994-11-19	1995-11-20	Production of variant nisin

Publications (1)

Publication Number	Publication Date
ATE292686T1 true ATE292686T1 (de)	2005-04-15

Family

ID=10764691

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95937939T ATE292686T1 (de)	1994-11-19	1995-11-20	Herstellung von nisin-varianten

Country Status (19)

Country	Link
US (1)	US6448034B1 (de)
EP (1)	EP0793727B1 (de)
JP (1)	JPH11500604A (de)
KR (1)	KR970707290A (de)
CN (1)	CN1085249C (de)
AT (1)	ATE292686T1 (de)
AU (1)	AU708788B2 (de)
BR (1)	BR9510454A (de)
CA (1)	CA2205204A1 (de)
CZ (1)	CZ152197A3 (de)
DE (1)	DE69534133T2 (de)
FI (1)	FI972100A7 (de)
GB (1)	GB9423404D0 (de)
HU (1)	HUT77421A (de)
NO (1)	NO972277L (de)
NZ (1)	NZ295425A (de)
PL (1)	PL320328A1 (de)
SK (1)	SK62297A3 (de)
WO (1)	WO1996016180A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5861275A (en) *	1995-09-28	1999-01-19	The University Of Maryland	Lantibiotic mutants and chimeras of enhanced stability and activity, leader sequences therefor, genes encoding the same, and methods of producing and using the same
US7034113B2 (en) *	2002-02-22	2006-04-25	Paradigm Diagnostics, Llc	Bacteriocin-metal complexes in the detection of pathogens and other biological analytes
US6861236B2 (en)	2002-05-24	2005-03-01	Applied Nanosystems B.V.	Export and modification of (poly)peptides in the lantibiotic way
BR0316776A (pt) *	2002-12-10	2005-10-25	Biosynexus Inc	Formula para anti-infeccioso tópico
CA2617133C (en) *	2005-07-28	2014-09-30	Biosynexus Incorporated	Compositions and methods for treating bacteria
WO2007092582A2 (en) *	2006-02-08	2007-08-16	Biosynexus Incorporated	Neutralization of bacterial spores
CA2865395A1 (en) *	2012-02-27	2013-09-06	Oragenics, Inc.	Variants of the lantibiotic mu1140 and other lantibiotics with improved pharmacological properties and structural features
CN110627880B (zh) *	2018-06-25	2024-03-19	武汉合生科技有限公司	分离的多肽及其应用
US20220240529A1 (en)	2019-05-31	2022-08-04	Chr. Hansen A/S	Composition comprising lactococcus, methods and products thereof
CN120865362A (zh) *	2025-08-20	2025-10-31	中国农业科学院农业质量标准与检测技术研究所	一种乳链菌肽的分离纯化方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3382675T2 (de) *	1983-09-06	1993-07-29	Microlife Technics	Abgeleitete nisin produzierende mikroorganismen, verfahren zur herstellung und verwendung und so erhaltene produkte.
WO1992018633A1 (en) *	1991-04-11	1992-10-29	Stichting Nederlands Instituut Voor Zuivelonderzoek (Nizo)	Lantibiotics similar to nisin a, lactic acid bacteria which produce such lantibiotics, method for constructing such lactic acid bacteria and method for preserving foodstuffs with the aid of these lantibiotics and these lactic acid bacteria producing lantibiotics
GB9207267D0 (en) *	1992-04-02	1992-05-13	Agricultural & Food Res	Nisins

1994
- 1994-11-19 GB GB9423404A patent/GB9423404D0/en active Pending
1995
- 1995-11-20 CN CN95197092A patent/CN1085249C/zh not_active Expired - Fee Related
- 1995-11-20 KR KR1019970703350A patent/KR970707290A/ko not_active Withdrawn
- 1995-11-20 NZ NZ295425A patent/NZ295425A/xx not_active IP Right Cessation
- 1995-11-20 CZ CZ971521A patent/CZ152197A3/cs unknown
- 1995-11-20 BR BR9510454A patent/BR9510454A/pt not_active Application Discontinuation
- 1995-11-20 EP EP95937939A patent/EP0793727B1/de not_active Expired - Lifetime
- 1995-11-20 WO PCT/GB1995/002699 patent/WO1996016180A1/en not_active Ceased
- 1995-11-20 HU HU9800206A patent/HUT77421A/hu unknown
- 1995-11-20 US US08/836,687 patent/US6448034B1/en not_active Expired - Fee Related
- 1995-11-20 AT AT95937939T patent/ATE292686T1/de not_active IP Right Cessation
- 1995-11-20 CA CA002205204A patent/CA2205204A1/en not_active Abandoned
- 1995-11-20 FI FI972100A patent/FI972100A7/fi not_active IP Right Cessation
- 1995-11-20 JP JP8516660A patent/JPH11500604A/ja active Pending
- 1995-11-20 DE DE69534133T patent/DE69534133T2/de not_active Expired - Fee Related
- 1995-11-20 SK SK622-97A patent/SK62297A3/sk unknown
- 1995-11-20 PL PL95320328A patent/PL320328A1/xx unknown
- 1995-11-20 AU AU38761/95A patent/AU708788B2/en not_active Ceased
1997
- 1997-05-20 NO NO972277A patent/NO972277L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CA2205204A1 (en)	1996-05-30
AU3876195A (en)	1996-06-17
DE69534133T2 (de)	2006-03-02
PL320328A1 (en)	1997-09-29
EP0793727B1 (de)	2005-04-06
FI972100A0 (fi)	1997-05-16
CN1171134A (zh)	1998-01-21
EP0793727A1 (de)	1997-09-10
KR970707290A (ko)	1997-12-01
SK62297A3 (en)	1997-12-10
US6448034B1 (en)	2002-09-10
BR9510454A (pt)	1998-12-15
FI972100L (fi)	1997-07-16
HUT77421A (hu)	1998-04-28
NO972277D0 (no)	1997-05-20
CN1085249C (zh)	2002-05-22
NZ295425A (en)	1999-07-29
JPH11500604A (ja)	1999-01-19
DE69534133D1 (de)	2005-05-12
CZ152197A3 (en)	1997-10-15
NO972277L (no)	1997-05-20
AU708788B2 (en)	1999-08-12
FI972100A7 (fi)	1997-07-16
GB9423404D0 (en)	1995-01-11
WO1996016180A1 (en)	1996-05-30

Similar Documents

Publication	Publication Date	Title
DE58900941D1 (de)	1992-04-16	Verwendung von 1,1,1,4,4,4-hexafluorbutan als treib- und daemmgas fuer die herstellung von kunststoff-schaumstoffen.
DE58902995D1 (de)	1993-01-28	Nichtfluechtige speicherzelle und verfahren zur herstellung.
DE58906718D1 (de)	1994-02-24	Kunststeine, verfahren zur herstellung und verwendung derselben.
DE3861018D1 (de)	1990-12-13	Mineralischer stoff, verfahren zu seiner herstellung und verwendung desselben.
DE69404883D1 (de)	1997-09-18	Verfahren zur Herstellung von sanften, ungekreppten, durchblasgetrockneten Blättern
DE3585542D1 (de)	1992-04-09	Methoden zur herstellung biologisch aktiver membranen und ihre verwendungen.
DE59303423D1 (de)	1996-09-19	Wachsdispersionen, deren herstellung und verwendung
DE3789304D1 (de)	1994-04-14	Allylgruppe enthaltende oligoäthylenoxypolyphosphazene, verfahren zur herstellung und sekundär batterien unter verwendung derselben.
DE68907447D1 (de)	1993-08-12	Geblasene, einstueckige flasche und verfahren zur herstellung derselben.
DE3750087D1 (de)	1994-07-21	Dekorblatt, sowie verfahren zur herstellung desselben.
ATE149523T1 (de)	1997-03-15	Verfahren zur herstellung von interferon-alpha-2 kristallen
DE69534133D1 (de)	2005-05-12	Herstellung von nisin-varianten
DE69001573D1 (de)	1993-06-17	Zusammensetzungen zur herstellung von in dosisformen aktiven vitaminen d3 sowie verfahren zur herstellung stabiler, in dosisformen aktiver vitamine d3 unter deren verwendung.
DE59003318D1 (de)	1993-12-09	Offenporige Formkörper, ihre Herstellung und ihre Verwendung.
DE3575071D1 (de)	1990-02-08	Epipodophyllotoxinchinon-glukosid-abkoemmlinge, verfahren zur herstellung und verwendung.
DE68906431D1 (de)	1993-06-17	Verlaengerte elektrolumineszierende zelle sowie verfahren zur herstellung.
DE3576361D1 (de)	1990-04-12	Rekombinante dna, damit transformierter mikroorganismus, und verfahren zur herstellung von menschlicher cu-zn superoxiddismutase unter verwendung des transformierten mikroorganismus.
DE59002322D1 (de)	1993-09-16	Verfahren zur herstellung von 1,1,1,3,3,3-hexafluorpropan und 2-chlor-1,1,1,3,3,3-hexafluorpropan.
ATE85030T1 (de)	1993-02-15	Verfahren zur herstellung von wasserstoffperoxid.
DE3779266D1 (de)	1992-06-25	Verfahren zur herstellung metallischer formkoerper, sowie damit hergestellte formkoerper.
DE58905117D1 (de)	1993-09-09	Verfahren zur herstellung von 4-chlor-2,5-dimethoxyanilin.
DE69518290D1 (de)	2000-09-14	Kornwachstumsverfahren zur Herstellung von Emulsionen mit hochbromidhaltigem, ultradünnem, tafelförmigem Korn
DE69502571D1 (de)	1998-06-25	Prozess für die Herstellung von fermentierbarem Material
DE58905793D1 (de)	1993-11-04	Schneideinsatz und verfahren zu seiner herstellung.
DE58901165D1 (de)	1992-05-21	Verfahren zur herstellung von 2,4-dihydroxybenzoesaeure.

Legal Events

Date	Code	Title	Description
2005-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties