ATE270890T1 - Optische papillarzirkulation verbesserende mittel - Google Patents

Optische papillarzirkulation verbesserende mittel

Info

Publication number: ATE270890T1
Authority: AT; Austria
Prior art keywords: optic nerve; nerve head; papillary; optical; circulation
Prior art date: 1998-01-29

Application number

AT99900647T

Other languages

English (en)

Inventor

Hideaki Hara

Masamitsu Shimazawa

Yasushi Iwakura

Tetsuya Sugiyama

Original Assignee

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-29

Filing date

1999-01-21

Publication date

2004-07-15

1999-01-21 Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv

2004-07-15 Application granted granted Critical

2004-07-15 Publication of ATE270890T1 publication Critical patent/ATE270890T1/de

Links

230000004087 circulation Effects 0.000 title abstract 3
230000003287 optical effect Effects 0.000 title 1
210000003733 optic disk Anatomy 0.000 abstract 3
239000003814 drug Substances 0.000 abstract 2
229940079593 drug Drugs 0.000 abstract 2
JQSAYKKFZOSZGJ-UHFFFAOYSA-N 1-[bis(4-fluorophenyl)methyl]-4-[(2,3,4-trimethoxyphenyl)methyl]piperazine Chemical compound COC1=C(OC)C(OC)=CC=C1CN1CCN(C(C=2C=CC(F)=CC=2)C=2C=CC(F)=CC=2)CC1 JQSAYKKFZOSZGJ-UHFFFAOYSA-N 0.000 abstract 1
206010067013 Normal tension glaucoma Diseases 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
230000017531 blood circulation Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000001077 hypotensive effect Effects 0.000 abstract 1
230000001965 increasing effect Effects 0.000 abstract 1
229950007692 lomerizine Drugs 0.000 abstract 1
201000002978 low tension glaucoma Diseases 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000009885 systemic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT99900647T 1998-01-29 1999-01-21 Optische papillarzirkulation verbesserende mittel ATE270890T1 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP1683198		1998-01-29
JP25237598		1998-09-07
PCT/JP1999/000202 WO1999038515A1 (en)	1998-01-29	1999-01-21	Optic papillary circulation improving agents

Publications (1)

Publication Number	Publication Date
ATE270890T1 true ATE270890T1 (de)	2004-07-15

Family

ID=26353257

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99900647T ATE270890T1 (de)	1998-01-29	1999-01-21	Optische papillarzirkulation verbesserende mittel

Country Status (11)

Country	Link
US (1)	US6387910B1 (de)
EP (1)	EP1051973B1 (de)
JP (1)	JP4456269B2 (de)
KR (1)	KR100585299B1 (de)
CN (1)	CN1149086C (de)
AT (1)	ATE270890T1 (de)
DE (1)	DE69918671T2 (de)
ES (1)	ES2224597T3 (de)
PT (1)	PT1051973E (de)
TW (1)	TW461815B (de)
WO (1)	WO1999038515A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5841529B2 (ja) *	2010-05-27	2016-01-13	あすか製薬株式会社	複素環化合物及びｈ１受容体拮抗剤
CN109580836A (zh) *	2018-12-31	2019-04-05	辰欣药业股份有限公司	一种盐酸洛美利嗪原料及制剂有关物质的检测方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS60222472A (ja)	1984-03-30	1985-11-07	Kanebo Ltd	新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
WO1990006118A1 (en)	1988-12-05	1990-06-14	Houston Biotechnology Incorporated	Therapeutic use of dihydropyrimidones and benzazepine and benzothiazepine derivatives in retinal or optic nerve dysfunction
FR2669132A1 (fr) *	1990-11-09	1992-05-15	Guerin James	Dispositif de memorisation d'informations connectable a un ordinateur.
CA2131101A1 (en)	1992-05-13	1993-11-25	Louis Desantis Jr.	Topical ophthalmic compositions comprising a combination of calcium antagonists with known antiglaucoma agents

1999
- 1999-01-21 WO PCT/JP1999/000202 patent/WO1999038515A1/ja not_active Ceased
- 1999-01-21 AT AT99900647T patent/ATE270890T1/de not_active IP Right Cessation
- 1999-01-21 US US09/601,231 patent/US6387910B1/en not_active Expired - Fee Related
- 1999-01-21 DE DE69918671T patent/DE69918671T2/de not_active Expired - Fee Related
- 1999-01-21 EP EP99900647A patent/EP1051973B1/de not_active Expired - Lifetime
- 1999-01-21 CN CNB998045942A patent/CN1149086C/zh not_active Expired - Fee Related
- 1999-01-21 JP JP2000529248A patent/JP4456269B2/ja not_active Expired - Fee Related
- 1999-01-21 ES ES99900647T patent/ES2224597T3/es not_active Expired - Lifetime
- 1999-01-21 PT PT99900647T patent/PT1051973E/pt unknown
- 1999-01-21 KR KR1020007008272A patent/KR100585299B1/ko not_active Expired - Fee Related
- 1999-01-22 TW TW088100938A patent/TW461815B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR100585299B1 (ko)	2006-06-01
CN1295475A (zh)	2001-05-16
CN1149086C (zh)	2004-05-12
DE69918671T2 (de)	2005-07-28
US6387910B1 (en)	2002-05-14
KR20010024889A (ko)	2001-03-26
EP1051973B1 (de)	2004-07-14
DE69918671D1 (de)	2004-08-19
ES2224597T3 (es)	2005-03-01
JP4456269B2 (ja)	2010-04-28
TW461815B (en)	2001-11-01
PT1051973E (pt)	2004-11-30
EP1051973A4 (de)	2002-02-06
EP1051973A1 (de)	2000-11-15
WO1999038515A1 (en)	1999-08-05

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Legal Events

Date

Code

Title

Description

2005-04-15

UEP

Publication of translation of european patent specification

Ref document number: 1051973

Country of ref document: EP

2010-10-15

REN

Ceased due to non-payment of the annual fee