ATE215821T1 - Entzündungshemmende augentropfen - Google Patents

Entzündungshemmende augentropfen

Info

Publication number: ATE215821T1
Authority: AT; Austria
Prior art keywords: eye drops; inflammatory eye; eyedrops; diclofenac sodium; inflammatory
Prior art date: 1995-01-20

Application number

AT95941885T

Other languages

English (en)

Inventor

Masanobu Takeuchi

Hiroki Maruyama

Hiroe Suzuki

Touru Oguma

Makoto Maeda

Original Assignee

Wakamoto Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-01-20

Filing date

1995-12-26

Publication date

2002-04-15

1995-12-26 Application filed by Wakamoto Pharma Co Ltd filed Critical Wakamoto Pharma Co Ltd

2002-04-15 Application granted granted Critical

2002-04-15 Publication of ATE215821T1 publication Critical patent/ATE215821T1/de

Links

239000003889 eye drop Substances 0.000 title abstract 3
229940012356 eye drops Drugs 0.000 title abstract 3
230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
229960001193 diclofenac sodium Drugs 0.000 abstract 2
JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 abstract 2
229920000858 Cyclodextrin Polymers 0.000 abstract 1
229960000686 benzalkonium chloride Drugs 0.000 abstract 1
229960001950 benzethonium chloride Drugs 0.000 abstract 1
UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 abstract 1
CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
GDSRMADSINPKSL-HSEONFRVSA-N gamma-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO GDSRMADSINPKSL-HSEONFRVSA-N 0.000 abstract 1
229940080345 gamma-cyclodextrin Drugs 0.000 abstract 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT95941885T 1995-01-20 1995-12-26 Entzündungshemmende augentropfen ATE215821T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2448595		1995-01-20
PCT/JP1995/002680 WO1996022088A1 (en)	1995-01-20	1995-12-26	Anti-inflammatory eyedrops

Publications (1)

Publication Number	Publication Date
ATE215821T1 true ATE215821T1 (de)	2002-04-15

Family

ID=26361998

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95941885T ATE215821T1 (de)	1995-01-20	1995-12-26	Entzündungshemmende augentropfen

Country Status (11)

Country	Link
US (1)	US5929115A (de)
EP (1)	EP0807434B1 (de)
JP (1)	JP3672569B2 (de)
AT (1)	ATE215821T1 (de)
AU (1)	AU690794B2 (de)
CA (1)	CA2210749C (de)
DE (1)	DE69526369T2 (de)
FI (1)	FI973060A7 (de)
NO (1)	NO973343L (de)
RU (1)	RU2136252C1 (de)
WO (1)	WO1996022088A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PT877600E (pt) *	1996-08-09	2004-02-27	Alcon Mfg Ltd	Sistemas conservantes para composicoes farmaceuticas contendo ciclodextrinas
RU2156128C1 (ru) *	2000-01-05	2000-09-20	Гапонюк Петр Яковлевич	Глазные капли для лечения воспалительных заболеваний глаз с аллергическими проявлениями
JP3450805B2 (ja) *	2000-08-08	2003-09-29	わかもと製薬株式会社	水性医薬組成物
RU2197246C2 (ru) *	2000-10-05	2003-01-27	Новикова Людмила Серафимовна	Глазной препарат и способ его получения
RU2193403C1 (ru) *	2001-05-23	2002-11-27	Московский научно-исследовательский институт глазных болезней им. Гельмгольца	Глазные капли для лечения аллергических конъюнктивитов и кератоконъюнктивитов
RU2216331C1 (ru) *	2002-02-26	2003-11-20	Уфимский научно-исследовательский институт глазных болезней	Глазные капли
US20040013729A1 (en) *	2002-07-18	2004-01-22	Buono Lawrence M.	Single-drop multiple-agent composition for topical delivery to the eye
KR20050092429A (ko) *	2003-01-22	2005-09-21	니찌방 가부시기가이샤	안질환 치료용 경피 흡수형 제제, 그 사용, 및 안질환치료약의 눈의 국소 조직으로의 이행 방법
JP4947977B2 (ja) *	2003-10-31	2012-06-06	わかもと製薬株式会社	可逆性熱ゲル化水性組成物
PT1905453E (pt) *	2005-07-13	2012-12-04	Santen Pharmaceutical Co Ltd	Composição conservante para utilização oftálmica
US20070232567A1 (en) *	2006-03-28	2007-10-04	Curtis Wright	Formulations Of Low Dose Non-Steroidal Anti-Inflammatory Drugs And Beta-Cyclodextrin
CN101410123A (zh)	2006-03-28	2009-04-15	杰佛林制药公司	低剂量的双氯芬酸和β－环糊精的制剂
BR112013034051A2 (pt) *	2011-06-29	2019-09-24	Allergan Inc	formulações de macrogol 15 hidroxiestearato
WO2013149075A1 (en) *	2012-03-29	2013-10-03	Cxl Ophthalmics, Llc	Compositions and methods for treating or preventing diseases associated with oxidative stress
EP3452093B1 (de) *	2016-05-06	2021-04-28	Sacsh Corp.	Ophthalmische zusammensetzungen
US11110073B2 (en) *	2017-03-24	2021-09-07	Cadila Healthcare Limited	Storage stable aqueous injectable solution comprising diclofenac
CA3074326A1 (en) *	2017-09-01	2019-03-07	Murray & Poole Enterprises, Ltd.	Methods and compositions for the treatment of ophthalmic conditions
US11707443B2 (en)	2019-09-26	2023-07-25	Rk Pharma Inc.	Storage stable aqueous parenteral solutions comprising diclofenac
WO2022156371A1 (zh) *	2021-01-22	2022-07-28	成都瑞沐生物医药科技有限公司	一种眼用制剂的载体或辅料及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS58174309A (ja) *	1982-04-06	1983-10-13	Wakamoto Pharmaceut Co Ltd	消炎点眼剤
JPS58174310A (ja) *	1982-04-06	1983-10-13	Wakamoto Pharmaceut Co Ltd	抗炎症点眼剤
JPS5929616A (ja) *	1982-08-10	1984-02-16	Kaken Pharmaceut Co Ltd	抗炎症眼科用液剤およびその製法
JPS60136516A (ja) *	1983-12-26	1985-07-20	Kaken Pharmaceut Co Ltd	抗炎症眼科用液剤およびその製法
DE3612537C1 (de) *	1986-04-14	1987-07-16	Dispersa Ag	Arzneimittel zur Behandlung von Entzuendungen im Auge
JPS6416728A (en) *	1987-07-07	1989-01-20	Santen Pharmaceutical Co Ltd	Aqueous preparation
DK174702B1 (da) *	1987-09-11	2003-09-29	Syntex Llc	Konserveringssystem til ophthalmiske formuleringer
US4960799A (en) *	1988-09-13	1990-10-02	Ciba-Geigy Corporation	Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
TW200402B (de) *	1990-08-13	1993-02-21	Senju Pharma Co
JPH0616547A (ja) *	1992-07-01	1994-01-25	Wakamoto Pharmaceut Co Ltd	消炎点眼剤
ES2079994B1 (es) *	1992-10-07	1996-08-01	Cusi Lab	Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica.
AU5599594A (en) *	1992-11-16	1994-06-08	Ciba-Geigy Ag	Polyvinyl alcohol/borate ophthalmic drug delivery system
RU2049467C1 (ru) *	1993-04-16	1995-12-10	Научно-исследовательская фирма "Ультрасан"	Антибактериальный, противовоспалительный препарат
RU2062079C1 (ru) *	1993-08-25	1996-06-20	Уфимский научно-исследовательский институт глазных болезней	Глазные капли
US5576311A (en) *	1994-11-30	1996-11-19	Pharmos Corporation	Cyclodextrins as suspending agents for pharmaceutical suspensions

1995
- 1995-12-26 AU AU43156/96A patent/AU690794B2/en not_active Ceased
- 1995-12-26 WO PCT/JP1995/002680 patent/WO1996022088A1/ja not_active Ceased
- 1995-12-26 RU RU97113691/14A patent/RU2136252C1/ru not_active IP Right Cessation
- 1995-12-26 FI FI973060A patent/FI973060A7/fi unknown
- 1995-12-26 EP EP95941885A patent/EP0807434B1/de not_active Expired - Lifetime
- 1995-12-26 CA CA002210749A patent/CA2210749C/en not_active Expired - Fee Related
- 1995-12-26 US US08/875,101 patent/US5929115A/en not_active Expired - Fee Related
- 1995-12-26 DE DE69526369T patent/DE69526369T2/de not_active Expired - Fee Related
- 1995-12-26 AT AT95941885T patent/ATE215821T1/de not_active IP Right Cessation
- 1995-12-26 JP JP52215596A patent/JP3672569B2/ja not_active Expired - Fee Related
1997
- 1997-07-18 NO NO973343A patent/NO973343L/no unknown

Also Published As

Publication number	Publication date
NO973343L (no)	1997-09-19
AU690794B2 (en)	1998-04-30
EP0807434A1 (de)	1997-11-19
DE69526369D1 (de)	2002-05-16
DE69526369T2 (de)	2002-11-07
CA2210749A1 (en)	1996-07-25
NO973343D0 (no)	1997-07-18
RU2136252C1 (ru)	1999-09-10
FI973060L (fi)	1997-07-18
AU4315696A (en)	1996-08-07
CA2210749C (en)	2001-04-10
EP0807434A4 (de)	1998-04-22
FI973060A0 (fi)	1997-07-18
US5929115A (en)	1999-07-27
WO1996022088A1 (en)	1996-07-25
FI973060A7 (fi)	1997-07-18
EP0807434B1 (de)	2002-04-10
JP3672569B2 (ja)	2005-07-20

Legal Events

Date	Code	Title	Description
2002-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE215821T1 (de)	2002-04-15	Entzündungshemmende augentropfen
TR199701654T1 (xx)	1998-05-21	4-Fenilaminotiyazol t�revleri.
PL312615A1 (en)	1996-04-29	Ophthalmologic solution based on diclofenac and tobramycine, and its applications
AU633754B2 (en)	1993-02-04	Composition for eye drops
NO308848B1 (no)	2000-11-06	Kromanforbindelse og farmasøytisk preparat som inneholder den
ES2093791T3 (es)	1997-01-01	Composiciones desinfectantes esporicidas, produccion y uso de las mismas.
FI970489L (fi)	1997-02-05	Paikallisesti käytettäviä silmälääkekoostumuksia, jotka sisältävät doksepiinijohdoksia ja soveltuvat allergisten silmäsairauksien hoitoon
DK0562512T3 (da)	2001-03-19	Sulfonamidocarbonylpyridin-2-carboxylsyreamider samt deres anvendelse som lægemidler
PT768086E (pt)	2003-01-31	Tratamento de tinido utilizando agentes neuroprotectores
AU557730B2 (en)	1987-01-08	Lens sterilizing solution using chlorhexidine
CA2189424A1 (en)	1995-11-30	Non-steroidal anti-inflammatory ophthalmic suspensions
RU97113691A (ru)	1999-06-10	Противовосполительные глазные капли
AU2388392A (en)	1993-02-23	Oxicam or oxicam derivatives-containing ophthalmic compositions
AU5707090A (en)	1991-01-31	Hair treatment composition
ATE204752T1 (de)	2001-09-15	Therapeutische anwendungen von 2',5'- oligoadenylat-derivaten
NO971604L (no)	1997-04-08	Orale sabeluzolsuspensjoner
YU48341B (sh)	1998-07-10	Preparat herbicida
IT1282289B1 (it)	1998-03-16	17-idrossiimminoalchil e 17-idrossiimminometilalchenil ciclopentaperidrofenantreni attivi sul sistema cardiovascolare,
NO995847L (no)	2000-01-28	Salter av optisk aktivt sulfoksydderivat
BR9712628A (pt)	1999-10-26	Derivados de 8(9)-deidroestradiol
SK2021U (sk)	1998-12-02	Očné kvapky s protizápalovým účinkom na báze 2-[(2,6-dichlórfenyl)amino] fenylacetátu sodného
ITFI910140U1 (it)	1993-05-08	Presidio dell'articolazione scapolo-omerale