ATE215821T1 - Entzündungshemmende augentropfen - Google Patents

Entzündungshemmende augentropfen

Info

Publication number: ATE215821T1
Authority: AT; Austria
Prior art keywords: eye drops; inflammatory eye; eyedrops; diclofenac sodium; inflammatory
Prior art date: 1995-01-20

Application number

AT95941885T

Other languages

English (en)

Inventor

Masanobu Takeuchi

Hiroki Maruyama

Hiroe Suzuki

Touru Oguma

Makoto Maeda

Original Assignee

Wakamoto Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-01-20

Filing date

1995-12-26

Publication date

2002-04-15

1995-12-26 Application filed by Wakamoto Pharma Co Ltd filed Critical Wakamoto Pharma Co Ltd

2002-04-15 Application granted granted Critical

2002-04-15 Publication of ATE215821T1 publication Critical patent/ATE215821T1/de

Links

239000003889 eye drop Substances 0.000 title abstract 3
229940012356 eye drops Drugs 0.000 title abstract 3
230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
229960001193 diclofenac sodium Drugs 0.000 abstract 2
JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 abstract 2
229920000858 Cyclodextrin Polymers 0.000 abstract 1
229960000686 benzalkonium chloride Drugs 0.000 abstract 1
229960001950 benzethonium chloride Drugs 0.000 abstract 1
UREZNYTWGJKWBI-UHFFFAOYSA-M benzethonium chloride Chemical compound [Cl-].C1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 UREZNYTWGJKWBI-UHFFFAOYSA-M 0.000 abstract 1
CADWTSSKOVRVJC-UHFFFAOYSA-N benzyl(dimethyl)azanium;chloride Chemical compound [Cl-].C[NH+](C)CC1=CC=CC=C1 CADWTSSKOVRVJC-UHFFFAOYSA-N 0.000 abstract 1
GDSRMADSINPKSL-HSEONFRVSA-N gamma-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO GDSRMADSINPKSL-HSEONFRVSA-N 0.000 abstract 1
229940080345 gamma-cyclodextrin Drugs 0.000 abstract 1
235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Ophthalmology & Optometry (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT95941885T 1995-01-20 1995-12-26 Entzündungshemmende augentropfen ATE215821T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2448595		1995-01-20
PCT/JP1995/002680 WO1996022088A1 (en)	1995-01-20	1995-12-26	Anti-inflammatory eyedrops

Publications (1)

Publication Number	Publication Date
ATE215821T1 true ATE215821T1 (de)	2002-04-15

Family

ID=26361998

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95941885T ATE215821T1 (de)	1995-01-20	1995-12-26	Entzündungshemmende augentropfen

Country Status (11)

Country	Link
US (1)	US5929115A (de)
EP (1)	EP0807434B1 (de)
JP (1)	JP3672569B2 (de)
AT (1)	ATE215821T1 (de)
AU (1)	AU690794B2 (de)
CA (1)	CA2210749C (de)
DE (1)	DE69526369T2 (de)
FI (1)	FI973060L (de)
NO (1)	NO973343L (de)
RU (1)	RU2136252C1 (de)
WO (1)	WO1996022088A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0877600B1 (de) *	1996-08-09	2003-10-22	Alcon Manufacturing Ltd.	Konservierungssysteme fur cyclodextrine enthaltende arzneimittel
RU2156128C1 (ru) *	2000-01-05	2000-09-20	Гапонюк Петр Яковлевич	Глазные капли для лечения воспалительных заболеваний глаз с аллергическими проявлениями
JP3450805B2 (ja) *	2000-08-08	2003-09-29	わかもと製薬株式会社	水性医薬組成物
RU2197246C2 (ru) *	2000-10-05	2003-01-27	Новикова Людмила Серафимовна	Глазной препарат и способ его получения
RU2193403C1 (ru) *	2001-05-23	2002-11-27	Московский научно-исследовательский институт глазных болезней им. Гельмгольца	Глазные капли для лечения аллергических конъюнктивитов и кератоконъюнктивитов
RU2216331C1 (ru) *	2002-02-26	2003-11-20	Уфимский научно-исследовательский институт глазных болезней	Глазные капли
US20040013729A1 (en) *	2002-07-18	2004-01-22	Buono Lawrence M.	Single-drop multiple-agent composition for topical delivery to the eye
WO2004064817A1 (ja) *	2003-01-22	2004-08-05	Nichiban Co., Ltd.	眼疾患治療用経皮吸収型製剤、その使用、及び眼疾患治療薬の眼の局所組織への移行方法
EP1681065A4 (de) *	2003-10-31	2011-12-28	Wakamoto Pharma Co Ltd	Zusammensetzung auf wasserbasis mit reversibler thermogelierung
US20080269353A1 (en) *	2005-07-13	2008-10-30	Santen Pharmaceutical Co., Ltd.	Preventative Composition For Ophthalmic Use
MX2008012495A (es) *	2006-03-28	2009-01-07	Javelin Pharmaceuticals Inc	Formulaciones de dosis baja de diclofenaco y beta-ciclodextrina.
KR20090010953A (ko) *	2006-03-28	2009-01-30	자블린 파머슈티칼스 인코포레이티드	저 복용량의 비-스테로이드성 항염증성 약물 및 베타-사이클로덱스트린 제형
WO2013003827A2 (en) *	2011-06-29	2013-01-03	Allergan, Inc.	Macrogol 15 hydroxystearate formulations
US9566301B2 (en) *	2012-03-29	2017-02-14	Cxl Ophthalmics, Llc	Compositions and methods for treating or preventing diseases associated with oxidative stress
JP6941157B2 (ja) *	2016-05-06	2021-09-29	サックシュ・コーポレーション	眼科用組成物
US11110073B2 (en) *	2017-03-24	2021-09-07	Cadila Healthcare Limited	Storage stable aqueous injectable solution comprising diclofenac
WO2019043169A1 (en) *	2017-09-01	2019-03-07	Murray & Poole Enterprises, Ltd	METHODS AND COMPOSITIONS FOR THE TREATMENT OF OPHTHALMIC CONDITIONS
US11707443B2 (en)	2019-09-26	2023-07-25	Rk Pharma Inc.	Storage stable aqueous parenteral solutions comprising diclofenac
WO2022156371A1 (zh) *	2021-01-22	2022-07-28	成都瑞沐生物医药科技有限公司	一种眼用制剂的载体或辅料及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS58174310A (ja) *	1982-04-06	1983-10-13	Wakamoto Pharmaceut Co Ltd	抗炎症点眼剤
JPS58174309A (ja) *	1982-04-06	1983-10-13	Wakamoto Pharmaceut Co Ltd	消炎点眼剤
JPS5929616A (ja) *	1982-08-10	1984-02-16	Kaken Pharmaceut Co Ltd	抗炎症眼科用液剤およびその製法
JPS60136516A (ja) *	1983-12-26	1985-07-20	Kaken Pharmaceut Co Ltd	抗炎症眼科用液剤およびその製法
DE3612537C1 (de) *	1986-04-14	1987-07-16	Dispersa Ag	Arzneimittel zur Behandlung von Entzuendungen im Auge
JPS6416728A (en) *	1987-07-07	1989-01-20	Santen Pharmaceutical Co Ltd	Aqueous preparation
ZA886757B (en) *	1987-09-11	1990-05-30	Syntex Inc	Preservative system for ophthalmics formulations
US4960799A (en) *	1988-09-13	1990-10-02	Ciba-Geigy Corporation	Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
TW200402B (de) *	1990-08-13	1993-02-21	Senju Pharma Co
JPH0616547A (ja) *	1992-07-01	1994-01-25	Wakamoto Pharmaceut Co Ltd	消炎点眼剤
ES2079994B1 (es) *	1992-10-07	1996-08-01	Cusi Lab	Formulacion farmaceutica a base de polimixina-trimetoprim y un agente antiinflamatorio para su utilizacion topica oftalmica y otica.
WO1994010976A1 (en) *	1992-11-16	1994-05-26	Ciba Vision Ag, Hettlingen	Polyvinyl alcohol/borate ophthalmic drug delivery system
RU2049467C1 (ru) *	1993-04-16	1995-12-10	Научно-исследовательская фирма "Ультрасан"	Антибактериальный, противовоспалительный препарат
RU2062079C1 (ru) *	1993-08-25	1996-06-20	Уфимский научно-исследовательский институт глазных болезней	Глазные капли
US5576311A (en) *	1994-11-30	1996-11-19	Pharmos Corporation	Cyclodextrins as suspending agents for pharmaceutical suspensions

1995
- 1995-12-26 AU AU43156/96A patent/AU690794B2/en not_active Ceased
- 1995-12-26 US US08/875,101 patent/US5929115A/en not_active Expired - Fee Related
- 1995-12-26 WO PCT/JP1995/002680 patent/WO1996022088A1/ja not_active Ceased
- 1995-12-26 JP JP52215596A patent/JP3672569B2/ja not_active Expired - Fee Related
- 1995-12-26 FI FI973060A patent/FI973060L/fi unknown
- 1995-12-26 DE DE69526369T patent/DE69526369T2/de not_active Expired - Fee Related
- 1995-12-26 CA CA002210749A patent/CA2210749C/en not_active Expired - Fee Related
- 1995-12-26 AT AT95941885T patent/ATE215821T1/de not_active IP Right Cessation
- 1995-12-26 EP EP95941885A patent/EP0807434B1/de not_active Expired - Lifetime
- 1995-12-26 RU RU97113691/14A patent/RU2136252C1/ru not_active IP Right Cessation
1997
- 1997-07-18 NO NO973343A patent/NO973343L/no unknown

Also Published As

Publication number	Publication date
DE69526369T2 (de)	2002-11-07
EP0807434A1 (de)	1997-11-19
NO973343L (no)	1997-09-19
WO1996022088A1 (en)	1996-07-25
FI973060A0 (fi)	1997-07-18
EP0807434B1 (de)	2002-04-10
EP0807434A4 (de)	1998-04-22
FI973060A7 (fi)	1997-07-18
DE69526369D1 (de)	2002-05-16
US5929115A (en)	1999-07-27
CA2210749C (en)	2001-04-10
JP3672569B2 (ja)	2005-07-20
NO973343D0 (no)	1997-07-18
AU4315696A (en)	1996-08-07
FI973060L (fi)	1997-07-18
CA2210749A1 (en)	1996-07-25
AU690794B2 (en)	1998-04-30
RU2136252C1 (ru)	1999-09-10

Legal Events

Date	Code	Title	Description
2002-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69526369D1 (de)	2002-05-16	Entzündungshemmende augentropfen
TR199701654T1 (xx)	1998-05-21	4-Fenilaminotiyazol t�revleri.
PL312615A1 (en)	1996-04-29	Ophthalmologic solution based on diclofenac and tobramycine, and its applications
AU633754B2 (en)	1993-02-04	Composition for eye drops
NO308848B1 (no)	2000-11-06	Kromanforbindelse og farmasøytisk preparat som inneholder den
ES2093791T3 (es)	1997-01-01	Composiciones desinfectantes esporicidas, produccion y uso de las mismas.
FI970489L (fi)	1997-02-05	Paikallisesti käytettäviä silmälääkekoostumuksia, jotka sisältävät doksepiinijohdoksia ja soveltuvat allergisten silmäsairauksien hoitoon
DK0562512T3 (da)	2001-03-19	Sulfonamidocarbonylpyridin-2-carboxylsyreamider samt deres anvendelse som lægemidler
ES2181853T3 (es)	2003-03-01	Tratamiento del tinnitus empleando agentes neuroprotectores.
AU557730B2 (en)	1987-01-08	Lens sterilizing solution using chlorhexidine
CA2189424A1 (en)	1995-11-30	Non-steroidal anti-inflammatory ophthalmic suspensions
RU97113691A (ru)	1999-06-10	Противовосполительные глазные капли
AU2388392A (en)	1993-02-23	Oxicam or oxicam derivatives-containing ophthalmic compositions
AU5707090A (en)	1991-01-31	Hair treatment composition
ATE204752T1 (de)	2001-09-15	Therapeutische anwendungen von 2',5'- oligoadenylat-derivaten
NO971604L (no)	1997-04-08	Orale sabeluzolsuspensjoner
MA23133A1 (fr)	1994-10-01	Derives d'acide d'acyloxyhexanoique .
YU48341B (sh)	1998-07-10	Preparat herbicida
IT1282289B1 (it)	1998-03-16	17-idrossiimminoalchil e 17-idrossiimminometilalchenil ciclopentaperidrofenantreni attivi sul sistema cardiovascolare,
ES2116399T3 (es)	1998-07-16	Derivados tiazolicos de alcoxiacrilatos con una actividad fungicida.
NO995847L (no)	2000-01-28	Salter av optisk aktivt sulfoksydderivat
BR9712628A (pt)	1999-10-26	Derivados de 8(9)-deidroestradiol
SK2021U (sk)	1998-12-02	Očné kvapky s protizápalovým účinkom na báze 2-[(2,6-dichlórfenyl)amino] fenylacetátu sodného
BR7300396U (pt)	1994-10-25	Arca de noé, templo de adoração e adorno