ATE271563T1 - Neues verfahren zur herstellung von cyklosporinderivaten - Google Patents
Neues verfahren zur herstellung von cyklosporinderivatenInfo
- Publication number
- ATE271563T1 ATE271563T1 AT98962475T AT98962475T ATE271563T1 AT E271563 T1 ATE271563 T1 AT E271563T1 AT 98962475 T AT98962475 T AT 98962475T AT 98962475 T AT98962475 T AT 98962475T AT E271563 T1 ATE271563 T1 AT E271563T1
- Authority
- AT
- Austria
- Prior art keywords
- new process
- cyclosporine derivatives
- producing
- producing cyclosporine
- derivatives
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9716189A FR2772768B1 (fr) | 1997-12-19 | 1997-12-19 | Nouveau procede de preparation de derives de cyclosporine |
| PCT/FR1998/002745 WO1999032512A1 (fr) | 1997-12-19 | 1998-12-16 | Nouveau procede de preparation de derives de cyclosporine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE271563T1 true ATE271563T1 (de) | 2004-08-15 |
Family
ID=9514865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98962475T ATE271563T1 (de) | 1997-12-19 | 1998-12-16 | Neues verfahren zur herstellung von cyklosporinderivaten |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1040121B1 (de) |
| JP (1) | JP3980269B2 (de) |
| AR (1) | AR014136A1 (de) |
| AT (1) | ATE271563T1 (de) |
| AU (1) | AU1764099A (de) |
| DE (1) | DE69825179T2 (de) |
| DK (1) | DK1040121T3 (de) |
| ES (1) | ES2224454T3 (de) |
| FR (1) | FR2772768B1 (de) |
| MA (1) | MA26585A1 (de) |
| PE (1) | PE20020526A1 (de) |
| PT (1) | PT1040121E (de) |
| TN (1) | TNSN98231A1 (de) |
| WO (1) | WO1999032512A1 (de) |
| ZA (1) | ZA9811531B (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2780061B1 (fr) * | 1998-06-22 | 2001-09-07 | Rhone Poulenc Rorer Sa | Nouveau procede de preparation de derives de cyclosporine |
| WO2003033526A2 (en) * | 2001-10-19 | 2003-04-24 | Isotechnika Inc. | Synthesis of cyclosporin analogs |
| KR20040039622A (ko) * | 2002-11-04 | 2004-05-12 | 주식회사 엘지생활건강 | 모발 성장 효과를 갖는 사이클로스포린 3 위치 유도체를유효성분으로 하는 모발 성장 촉진제 |
| JP2006524232A (ja) | 2003-03-17 | 2006-10-26 | アルバニー モレキュラー リサーチ インコーポレーティッド | 新規サイクロスポリン |
| JP2008514701A (ja) | 2004-09-29 | 2008-05-08 | エーエムアール テクノロジー インコーポレイテッド | シクロスポリンアルキン類似体およびそれらの薬学的使用 |
| EP1804823A4 (de) | 2004-09-29 | 2010-06-09 | Amr Technology Inc | Neue cyclosporin-analoga und ihre pharmazeutischen anwendungen |
| US7196161B2 (en) | 2004-10-01 | 2007-03-27 | Scynexis Inc. | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection |
| US7361636B2 (en) | 2004-10-06 | 2008-04-22 | Amr Technology, Inc. | Cyclosporin alkynes and their utility as pharmaceutical agents |
| BRPI0616476A2 (pt) | 2005-09-30 | 2011-06-21 | Scynexis Inc | uso de uma quantidade terapeuticamente eficaz de um derivado de ciclosporina, e, composição farmacêutica |
| US8329658B2 (en) | 2005-09-30 | 2012-12-11 | Scynexis, Inc. | Arylalkyl and heteroarylalkyl derivatives of cyclosporine A for the treatment and prevention of viral infection |
| ATE502633T1 (de) | 2006-05-19 | 2011-04-15 | Scynexis Inc | Cyclosporins zur behandlung und vorbeugung von augenerkrankungen |
| US7576057B2 (en) | 2006-11-20 | 2009-08-18 | Scynexis, Inc. | Cyclic peptides |
| US9090671B2 (en) | 2008-06-06 | 2015-07-28 | Scynexis, Inc. | Macrocyclic peptides |
| EP2376524B1 (de) | 2008-12-31 | 2017-03-15 | Cypralis Limited | Derivate von cyclosporin a |
| AU2010254316A1 (en) * | 2009-05-27 | 2011-12-22 | Allergan, Inc. | Cyclosporin derivatives for treating inflammatory diseases and conditions |
| AU2010339460A1 (en) | 2009-12-30 | 2012-07-19 | Scynexis Inc. | Cyclosporine analogues |
| US9175042B2 (en) * | 2010-10-12 | 2015-11-03 | Allergan, Inc. | Cyclosporin analogs |
| JP6144627B2 (ja) | 2010-12-15 | 2017-06-07 | コントラヴィア ファーマシューティカルズ、インク． | アミノ酸１および３で修飾されたシクロスポリン類似体分子 |
| WO2020037530A1 (en) * | 2018-08-22 | 2020-02-27 | Waterstone Pharmaceuticals (Wuhan) Co., Ltd. | Crystalline form of compound and uses thereof in medicine |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0194972B1 (de) * | 1985-03-11 | 1992-07-29 | Sandoz Ag | Cyclosporine |
| PL324531A1 (en) * | 1995-07-17 | 1998-06-08 | Chem Ag C | Derivatives of cyclosporin effective against hiv virus |
-
1997
- 1997-12-19 FR FR9716189A patent/FR2772768B1/fr not_active Expired - Fee Related
-
1998
- 1998-12-15 ZA ZA9811531A patent/ZA9811531B/xx unknown
- 1998-12-15 MA MA25395A patent/MA26585A1/fr unknown
- 1998-12-16 PT PT98962475T patent/PT1040121E/pt unknown
- 1998-12-16 EP EP98962475A patent/EP1040121B1/de not_active Expired - Lifetime
- 1998-12-16 DK DK98962475T patent/DK1040121T3/da active
- 1998-12-16 ES ES98962475T patent/ES2224454T3/es not_active Expired - Lifetime
- 1998-12-16 WO PCT/FR1998/002745 patent/WO1999032512A1/fr not_active Ceased
- 1998-12-16 JP JP2000525449A patent/JP3980269B2/ja not_active Expired - Fee Related
- 1998-12-16 AU AU17640/99A patent/AU1764099A/en not_active Abandoned
- 1998-12-16 DE DE69825179T patent/DE69825179T2/de not_active Expired - Lifetime
- 1998-12-16 AT AT98962475T patent/ATE271563T1/de active
- 1998-12-17 TN TNTNSN98231A patent/TNSN98231A1/fr unknown
- 1998-12-18 AR ARP980106479A patent/AR014136A1/es unknown
-
2000
- 2000-11-23 PE PE2000001248A patent/PE20020526A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1040121B1 (de) | 2004-07-21 |
| DK1040121T3 (da) | 2004-11-29 |
| FR2772768A1 (fr) | 1999-06-25 |
| DE69825179D1 (de) | 2004-08-26 |
| WO1999032512A1 (fr) | 1999-07-01 |
| JP2002502803A (ja) | 2002-01-29 |
| JP3980269B2 (ja) | 2007-09-26 |
| AR014136A1 (es) | 2001-02-07 |
| ZA9811531B (en) | 1999-06-15 |
| TNSN98231A1 (fr) | 2005-03-15 |
| AU1764099A (en) | 1999-07-12 |
| PE20020526A1 (es) | 2002-07-10 |
| FR2772768B1 (fr) | 2000-01-14 |
| DE69825179T2 (de) | 2005-09-08 |
| PT1040121E (pt) | 2004-11-30 |
| MA26585A1 (fr) | 2004-12-20 |
| ES2224454T3 (es) | 2005-03-01 |
| EP1040121A1 (de) | 2000-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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