ATE219056T1 - Verfahren zur herstellung von alpha- bromolactamderivaten - Google Patents

Verfahren zur herstellung von alpha- bromolactamderivaten

Info

Publication number
ATE219056T1
ATE219056T1 AT98103570T AT98103570T ATE219056T1 AT E219056 T1 ATE219056 T1 AT E219056T1 AT 98103570 T AT98103570 T AT 98103570T AT 98103570 T AT98103570 T AT 98103570T AT E219056 T1 ATE219056 T1 AT E219056T1
Authority
AT
Austria
Prior art keywords
bromolactam
derivatives
producing alpha
alpha
producing
Prior art date
Application number
AT98103570T
Other languages
English (en)
Inventor
Stefan Abrecht
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Application granted granted Critical
Publication of ATE219056T1 publication Critical patent/ATE219056T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98103570T 1997-03-10 1998-03-02 Verfahren zur herstellung von alpha- bromolactamderivaten ATE219056T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97103964 1997-03-10

Publications (1)

Publication Number Publication Date
ATE219056T1 true ATE219056T1 (de) 2002-06-15

Family

ID=8226572

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98103570T ATE219056T1 (de) 1997-03-10 1998-03-02 Verfahren zur herstellung von alpha- bromolactamderivaten

Country Status (16)

Country Link
US (1) US6114541A (de)
EP (1) EP0864564B1 (de)
JP (1) JP2938427B2 (de)
KR (1) KR100280561B1 (de)
CN (1) CN1193014A (de)
AR (1) AR015571A1 (de)
AT (1) ATE219056T1 (de)
AU (1) AU728147B2 (de)
BR (1) BR9800844A (de)
CA (1) CA2231631A1 (de)
CY (1) CY2392B1 (de)
DE (1) DE69805887T2 (de)
DK (1) DK0864564T3 (de)
ES (1) ES2176841T3 (de)
TR (1) TR199800403A3 (de)
ZA (1) ZA981885B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901712D0 (sv) * 1999-05-11 1999-05-11 Astra Ab New process
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
TW201615643A (zh) 2014-06-02 2016-05-01 伊史帝夫博士實驗室股份有限公司 具有多重模式抗疼痛活性之1-氧雜-4,9-二氮雜螺十一烷化合物之烷基與芳基衍生物
TWI685497B (zh) 2014-06-02 2020-02-21 西班牙商伊史帝夫製藥公司 具有多重模式抗疼痛活性的1-氧雜-4,9-二氮雜螺十一烷化合物之烷基衍生物
US10421750B2 (en) 2015-10-23 2019-09-24 Esteve Pharmaceuticals, S.A. Substituted morpholine derivatives having activity against pain
DK3365346T3 (da) 2015-10-23 2020-03-09 Esteve Pharmaceuticals Sa Oxa-diazaspiroforbindelser med aktivitet mod smerter
ES2794801T3 (es) 2015-10-23 2020-11-19 Esteve Pharmaceuticals Sa Compuestos oxaazaespíricos con actividad contra el dolor
UA123775C2 (uk) 2015-11-16 2021-06-02 Естев Фармас'Ютікалз, С.А. Оксадіазаспіросполуки для лікування зловживання наркотичними засобами та залежності від них
CN107129454A (zh) * 2017-05-04 2017-09-05 唐山威格化学工业有限公司 N‑辛基吡咯烷酮的合成方法
TWI835755B (zh) 2017-10-17 2024-03-21 西班牙商塔拉森空調公司 (r)-9-(2,5-二氟苯乙基)-4-乙基-2-甲基-1-氧雜-4,9-二氮雜螺[5.5]十一烷-3-酮之鹽

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT620225E (pt) * 1993-04-16 2003-03-31 Basilea Pharmaceutica Ag Derivados de cefalosporina
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
US5811419A (en) * 1996-01-16 1998-09-22 Hoffmann-La Roche Inc. Isooxacephem-derivatives

Also Published As

Publication number Publication date
BR9800844A (pt) 2000-05-02
AR015571A1 (es) 2001-05-16
DE69805887D1 (de) 2002-07-18
AU728147B2 (en) 2001-01-04
ES2176841T3 (es) 2002-12-01
KR100280561B1 (ko) 2001-02-01
AU5737498A (en) 1998-09-10
TR199800403A2 (xx) 1998-09-21
KR19980080035A (ko) 1998-11-25
CN1193014A (zh) 1998-09-16
JPH10273481A (ja) 1998-10-13
EP0864564A1 (de) 1998-09-16
ZA981885B (en) 1998-09-10
EP0864564B1 (de) 2002-06-12
CA2231631A1 (en) 1998-09-10
CY2392B1 (en) 2004-09-10
DK0864564T3 (da) 2002-09-23
JP2938427B2 (ja) 1999-08-23
US6114541A (en) 2000-09-05
TR199800403A3 (tr) 1998-09-21
DE69805887T2 (de) 2003-02-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification