ATE273031T1 - Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen - Google Patents

Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen

Info

Publication number
ATE273031T1
ATE273031T1 AT98964242T AT98964242T ATE273031T1 AT E273031 T1 ATE273031 T1 AT E273031T1 AT 98964242 T AT98964242 T AT 98964242T AT 98964242 T AT98964242 T AT 98964242T AT E273031 T1 ATE273031 T1 AT E273031T1
Authority
AT
Austria
Prior art keywords
aminobiguanides
contact lenses
pharmaceutical preparations
disinfecting contact
preserving pharmaceutical
Prior art date
Application number
AT98964242T
Other languages
English (en)
Inventor
Joonsup Park
Nissanke L Dassanayake
Nathaniel D Mcqueen
Ronald L Schlitzer
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of ATE273031T1 publication Critical patent/ATE273031T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/141—Biguanides, e.g. chlorhexidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Eyeglasses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98964242T 1997-12-19 1998-12-18 Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen ATE273031T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6833097P 1997-12-19 1997-12-19
PCT/US1998/027332 WO1999032158A2 (en) 1997-12-19 1998-12-18 Aminobiguanides to disinfect contact lenses and preserve pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE273031T1 true ATE273031T1 (de) 2004-08-15

Family

ID=22081876

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98964242T ATE273031T1 (de) 1997-12-19 1998-12-18 Aminobiguanide und ihre verwendung zur desinfektion von kontaktlinsen und konservierung von pharmazeutischen zubereitungen

Country Status (16)

Country Link
US (2) US6664294B1 (de)
EP (1) EP1042007B1 (de)
JP (1) JP4027595B2 (de)
KR (1) KR100489905B1 (de)
AR (1) AR016708A1 (de)
AT (1) ATE273031T1 (de)
AU (1) AU751002B2 (de)
BR (1) BR9814299A (de)
CA (1) CA2309172C (de)
DE (1) DE69825625T2 (de)
ES (1) ES2226198T3 (de)
NO (1) NO20003119D0 (de)
NZ (1) NZ505742A (de)
TW (1) TW516960B (de)
WO (1) WO1999032158A2 (de)
ZA (1) ZA9811445B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA9811445B (en) 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
WO2001054687A1 (en) * 2000-01-25 2001-08-02 Alcon Universal Ltd. Ophthalmic anti-allergy compositions suitable for use with contact lenses
US8097270B2 (en) 2001-12-21 2012-01-17 Novartis Ag Use of nanoparticles as carriers for biocides in ophthalmic compositions
US20050003014A1 (en) 2001-12-21 2005-01-06 Ketelson Howard Allen Use of synthetic inorganic nanoparticles as carriers for ophthalmic and otic drugs
TWI354021B (en) 2002-12-23 2011-12-11 Alcon Inc Compositions and methods for inhibiting protein on
TWI322828B (en) * 2002-12-23 2010-04-01 Alcon Inc Use of multifunctional surface active agents to clean contact lenses
US20050118129A1 (en) * 2003-12-01 2005-06-02 Erning Xia Gentle and enhanced preservative systems
US6936640B2 (en) * 2003-12-04 2005-08-30 Alcon, Inc. Biguanide/quaternary ammonium containing copolymeric biocides and use thereof in pharmaceutical compositions
DE602004020665D1 (de) * 2003-12-09 2009-05-28 Alcon Inc Verwendung von bisaminen zur verstärkung der antimn
JP2007513951A (ja) * 2003-12-09 2007-05-31 アルコン、インコーポレイテッド 医薬品組成物の抗菌活性を増強する有機緩衝剤の使用
JP5033380B2 (ja) * 2006-08-30 2012-09-26 ディバーシー株式会社 食器、調理器具、食品加工場内もしくは厨房内の設備用殺菌剤組成物および殺菌洗浄剤組成物、ならびにこれらを用いた食器、調理器具、食品加工場内もしくは厨房内の設備の殺菌方法あるいは殺菌洗浄方法
TWI434926B (zh) * 2006-12-11 2014-04-21 Alcon Res Ltd 眼用組成物中聚氧化乙烯-聚氧化丁烯（ｐｅｏ-ｐｂｏ）嵌段共聚物之使用
US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
FR2928519B1 (fr) * 2008-03-13 2012-12-21 Ogf Nouvelle composition pour la conservation des tissus
US8093352B2 (en) * 2008-08-05 2012-01-10 Alcon Research, Ltd. Polyalkylene oxide polyquaternary ammonium biocides
CN102186908B (zh) 2008-09-19 2013-10-16 3M创新有限公司 配体接枝官能化基材
US20100086513A1 (en) * 2008-09-30 2010-04-08 Oliveira Marcos A Method for Effecting Antimicrobial Activity Using Polyamine Analogues
US8431751B1 (en) 2008-12-24 2013-04-30 Alcon Research, Ltd. Polymeric quaternary ammonium compounds with vicinal hydroxy groups
TW201105369A (en) * 2009-05-29 2011-02-16 Alcon Res Ltd N-halamine formulations with enhanced antimicrobial activity
TWI547522B (zh) * 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
WO2011153349A1 (en) 2010-06-02 2011-12-08 Alcon Research, Ltd. Ophthalmic compositions comprising pbo-peo-pbo block copolymers
EP3876737A4 (de) 2018-11-08 2021-12-29 Hwang-Hsing Chen Tris-substituierte biguanidverbindungen und deren verwendungen

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3270036A (en) * 1965-10-07 1966-08-30 Squibb & Sons Inc Adamantylbiguanides
GB1351025A (en) 1971-08-20 1974-04-24 Aron Md Samuel J Oxadiazol-5-yl biguanide derivatives method for their preparation and pharmaceutical compositions containing them
EP0055515B1 (de) 1980-12-18 1985-02-20 Smith and Nephew Associated Companies p.l.c. Sterilisationszubereitungen für Linsen und ihre Anwendung
US4407791A (en) 1981-09-28 1983-10-04 Alcon Laboratories, Inc. Ophthalmic solutions
GB8312664D0 (en) 1983-05-09 1983-06-15 Ici Plc Bis(1-substituted biguanide)derivatives
US4537746A (en) 1983-12-29 1985-08-27 Bausch & Lomb Incorporated Methods for disinfecting and preserving contact lenses
DE3575672D1 (de) 1985-07-22 1990-03-08 Bausch & Lomb Verfahren und loesung zur desinfektion und konservierung von kontaktlinsen.
US5185337A (en) 1989-03-29 1993-02-09 Otsuka Pharmaceutical Co., Ltd. Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use
US5262411A (en) 1989-12-29 1993-11-16 Otsuka Pharmaceutical Co., Ltd. Isocephem derivatives, and antimicrobial composition containing the derivatives
JPH0426668A (ja) * 1990-05-10 1992-01-29 Hb Fuller Licensing & Financing Inc 新規の生物致死組成物
CA2064664C (en) * 1991-04-05 2000-01-11 Hiroshi Ishikawa Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
EP0575290B1 (de) * 1992-06-17 2006-08-23 Novartis AG Kontaktlinsenpflegemittel für harte und weiche Kontaktlinsen
TW203128B (en) 1992-06-17 1993-04-01 Ciba Geigy Ag The protection method for hard and soft contact lens
JP3452572B2 (ja) 1993-01-07 2003-09-29 ポリマー テクノロジー コーポレイション コンタクトレンズ溶液用の防腐剤系
WO1994025426A1 (en) 1993-04-28 1994-11-10 Alcon Laboratories, Inc. Diamines as antimicrobial agents and use thereof in ophthalmic composition
US5631005A (en) 1994-09-21 1997-05-20 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5415837A (en) 1993-10-25 1995-05-16 Alcon Laboratories, Inc. Use of diamines to disinfect and clean contact lenses
ZA9811445B (en) 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.

Also Published As

Publication number Publication date
JP4027595B2 (ja) 2007-12-26
NO20003119L (no) 2000-06-16
KR100489905B1 (ko) 2005-05-17
HK1029290A1 (en) 2001-03-30
ZA9811445B (en) 1999-08-16
JP2001526090A (ja) 2001-12-18
WO1999032158A3 (en) 1999-09-02
TW516960B (en) 2003-01-11
WO1999032158A2 (en) 1999-07-01
US6916958B2 (en) 2005-07-12
CA2309172A1 (en) 1999-07-01
BR9814299A (pt) 2001-10-30
AU751002B2 (en) 2002-08-08
NO20003119D0 (no) 2000-06-16
CA2309172C (en) 2006-07-11
AU1941599A (en) 1999-07-12
ES2226198T3 (es) 2005-03-16
AR016708A1 (es) 2001-07-25
DE69825625T2 (de) 2005-09-15
EP1042007A2 (de) 2000-10-11
KR20010033339A (ko) 2001-04-25
EP1042007B1 (de) 2004-08-11
US6664294B1 (en) 2003-12-16
DE69825625D1 (de) 2004-09-16
US20040063791A1 (en) 2004-04-01
NZ505742A (en) 2002-11-26

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