ATE27452T1 - Substituierte o-phenylendiaminderivate. - Google Patents

Substituierte o-phenylendiaminderivate.

Info

Publication number: ATE27452T1
Authority: AT; Austria
Prior art keywords: alkyl; conhch3; conh2; substituted; nhcoch3
Prior art date: 1982-05-24

Application number

AT83302921T

Other languages

English (en)

Inventor

Graham John Atwell

Bruce Charles Baguley

William Alexander Denny

Gordon William Rewcastle

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-05-24

Filing date

1983-05-20

Publication date

1987-06-15

1983-05-20 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

1987-06-15 Application granted granted Critical

1987-06-15 Publication of ATE27452T1 publication Critical patent/ATE27452T1/de

Links

150000004987 o-phenylenediamines Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 4
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 3
-1 O-alkyl Chemical group 0.000 abstract 2
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000001335 aliphatic alkanes Chemical group 0.000 abstract 1
MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
230000000259 anti-tumor effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/22—Amides of acids of phosphorus
- C07F9/24—Esteramides
- C07F9/2454—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
- C07F9/247—Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aromatic amines (N-C aromatic linkage)

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)
Other In-Based Heterocyclic Compounds (AREA)

AT83302921T 1982-05-24 1983-05-20 Substituierte o-phenylendiaminderivate. ATE27452T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NZ200715A NZ200715A (en)	1982-05-24	1982-05-24	Acridine derivatives and pharmaceutical compositions containing such
EP83302921A EP0095355B1 (de)	1982-05-24	1983-05-20	Substituierte o-Phenylendiaminderivate

Publications (1)

Publication Number	Publication Date
ATE27452T1 true ATE27452T1 (de)	1987-06-15

Family

ID=19919975

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT83302921T ATE27452T1 (de)	1982-05-24	1983-05-20	Substituierte o-phenylendiaminderivate.

Country Status (6)

Country	Link
US (1)	US4603125A (de)
EP (1)	EP0095355B1 (de)
JP (1)	JPS5916869A (de)
AT (1)	ATE27452T1 (de)
DE (2)	DE3371782D1 (de)
NZ (1)	NZ200715A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ200715A (en) *	1982-05-24	1986-06-11	New Zealand Dev Finance	Acridine derivatives and pharmaceutical compositions containing such
US4795826A (en) *	1982-05-24	1989-01-03	Atwell Graham J	Ortho-phenylenediamine compounds
JPS63101369A (ja) *	1986-10-17	1988-05-06	Mect Corp	インデノキノリン系化合物、その製造法及びその化合物を有効成分とする抗癌剤
JPH02256667A (ja) *	1988-12-27	1990-10-17	Masatoshi Yamato	縮合キノリン系化合物およびその製造方法
US5217961A (en) *	1988-12-27	1993-06-08	Mect Corporation	Condensed quinoline system N-glycosides
AU7579991A (en) *	1990-02-20	1991-09-18	Gilead Sciences, Inc.	Pseudonucleosides and pseudonucleotides and their polymers
US5354864A (en) *	1992-05-21	1994-10-11	Sloan-Kettering Institute For Cancer Research	3-(9-acridinylamino)-5-hydroxymethylaniline derivatives as anticancer agents
CA2400403C (en) *	2000-02-18	2011-07-19	New York Medical College	1-nitroacridine/tumor inhibitor compositions
US20020169183A1 (en) *	2001-03-08	2002-11-14	Villar Hugo O.	Acridines as stimulators for Fas-mediated apoptosis
US6914700B2 (en)	2003-04-17	2005-07-05	Lexmark International, Inc.	Method for reducing migrating residual error in error diffusion halftoning

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4060527A (en) *	1975-06-23	1977-11-29	Fuji Chemical Industries, Ltd.	Pyrido[2,3-c]-acridine-1-hydroxy-2-carboxylic acid derivatives
US4258191A (en) *	1979-03-29	1981-03-24	The United States Of America As Represented By The Secretary Of Health, Education And Welfare	Multi-step process for the production of methanesulfon-m-anisidide, 4'-(9-acridinylamino)-
DE2942511A1 (de) *	1979-10-20	1981-04-30	Basf Ag, 6700 Ludwigshafen	Verfahren zur hertellung von arylmono- und polyurethanen
AU534608B2 (en) *	1979-09-14	1984-02-09	Warner-Lambert Corporation	Compounds having antitumour properties
EP0039224B1 (de) *	1980-04-28	1984-06-27	Development Finance Corporation Of New Zealand	Verbindung mit Antitumor-Eigenschaften
NZ198115A (en) *	1981-08-21	1985-05-31	New Zealand Dev Finance	9-anilinoacridines;pharmaceutical compositions
NZ200715A (en) *	1982-05-24	1986-06-11	New Zealand Dev Finance	Acridine derivatives and pharmaceutical compositions containing such

1982
- 1982-05-24 NZ NZ200715A patent/NZ200715A/en unknown
1983
- 1983-05-20 EP EP83302921A patent/EP0095355B1/de not_active Expired
- 1983-05-20 DE DE8383302921T patent/DE3371782D1/de not_active Expired
- 1983-05-20 DE DE198383302921T patent/DE95355T1/de active Pending
- 1983-05-20 AT AT83302921T patent/ATE27452T1/de not_active IP Right Cessation
- 1983-05-20 JP JP58089047A patent/JPS5916869A/ja active Pending
- 1983-11-14 US US06/551,329 patent/US4603125A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US4603125A (en)	1986-07-29
EP0095355A1 (de)	1983-11-30
NZ200715A (en)	1986-06-11
EP0095355B1 (de)	1987-05-27
JPS5916869A (ja)	1984-01-28
DE3371782D1 (en)	1987-07-02
DE95355T1 (de)	1984-10-25

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Legal Events

Date	Code	Title	Description
1988-05-15	UEP	Publication of translation of european patent specification
1991-02-15	REN	Ceased due to non-payment of the annual fee