ATE274914T1 - Verfahren zur herstellung einer zusammensetzung enthaltend modifizierten tierlichen lungensurfactant - Google Patents
Verfahren zur herstellung einer zusammensetzung enthaltend modifizierten tierlichen lungensurfactantInfo
- Publication number
- ATE274914T1 ATE274914T1 AT96920616T AT96920616T ATE274914T1 AT E274914 T1 ATE274914 T1 AT E274914T1 AT 96920616 T AT96920616 T AT 96920616T AT 96920616 T AT96920616 T AT 96920616T AT E274914 T1 ATE274914 T1 AT E274914T1
- Authority
- AT
- Austria
- Prior art keywords
- surfactant
- lung surfactant
- lung
- phospholipid
- protein
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 229940066294 lung surfactant Drugs 0.000 title abstract 3
- 239000003580 lung surfactant Substances 0.000 title abstract 3
- 241001465754 Metazoa Species 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000011149 active material Substances 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 210000004072 lung Anatomy 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 102000018616 Apolipoproteins B Human genes 0.000 abstract 1
- 108010027006 Apolipoproteins B Proteins 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 230000006835 compression Effects 0.000 abstract 1
- 238000007906 compression Methods 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 230000002950 deficient Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 230000002269 spontaneous effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/42—Respiratory system, e.g. lungs, bronchi or lung cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Fodder In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/475,539 US6129934A (en) | 1995-06-07 | 1995-06-07 | Modification of animal lung surfactant for treating respiratory disease due to lung surfactant deficiency or dysfunction |
| PCT/US1996/008828 WO1996040177A1 (en) | 1995-06-07 | 1996-06-05 | Modified animal lung surfactant and its therapeutic use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE274914T1 true ATE274914T1 (de) | 2004-09-15 |
Family
ID=23888024
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96920616T ATE274914T1 (de) | 1995-06-07 | 1996-06-05 | Verfahren zur herstellung einer zusammensetzung enthaltend modifizierten tierlichen lungensurfactant |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6129934A (de) |
| EP (1) | EP0831862B1 (de) |
| AT (1) | ATE274914T1 (de) |
| AU (1) | AU5886896A (de) |
| CA (1) | CA2221625A1 (de) |
| DE (1) | DE69633279D1 (de) |
| WO (1) | WO1996040177A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5958902A (en) * | 1997-04-16 | 1999-09-28 | Wisconsin Alumni Research Foundation | Method and composition for treating sleep apnea |
| US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
| US6309623B1 (en) | 1997-09-29 | 2001-10-30 | Inhale Therapeutic Systems, Inc. | Stabilized preparations for use in metered dose inhalers |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| DE69920480T2 (de) * | 1998-07-30 | 2005-10-13 | Colgate-Palmolive Co. | Wasser-in-öl-mikroemulsion zur erzielung kosmetischer eigenschaften in zusammensetzungen auf basis von wäscheweichmachern |
| AU6083899A (en) * | 1999-09-16 | 2001-04-17 | Aventis Behring Gmbh | Combination of c1-inh and lung surfactant for the treatment of respiratory disorders |
| US6156294A (en) | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| US6676930B2 (en) | 1999-11-28 | 2004-01-13 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| AU2001265876A1 (en) * | 2000-04-12 | 2001-10-23 | Byk Gulden Lomberg Chemische Fabrik G.M.B.H. | Novel use of pulmonary surfactant for the prophylaxis or early treatment of acute pulmonary diseases |
| US20040254112A1 (en) * | 2000-04-12 | 2004-12-16 | Dietrich Hafner | Use of pulmonary surfactant for the early treatment of acute pulmonary diseases |
| US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
| US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
| US7442388B2 (en) | 2000-05-10 | 2008-10-28 | Weers Jeffry G | Phospholipid-based powders for drug delivery |
| JP2004507485A (ja) * | 2000-09-01 | 2004-03-11 | ラーソン，マーカス | 動的膨張挙動を有する肺界面活性組成物 |
| US7368102B2 (en) | 2001-12-19 | 2008-05-06 | Nektar Therapeutics | Pulmonary delivery of aminoglycosides |
| CA2487072A1 (en) * | 2002-05-23 | 2003-12-04 | Ortho-Clinical Diagnostics, Inc. | Capture, concentration and quantitation of abnormal prion protein from biological fluids using depth filtration |
| WO2006118966A2 (en) * | 2005-05-03 | 2006-11-09 | The Hospital For Sick Children | Phospholipid formulations and uses thereof in lung disease detection and treatment |
| EP4366691A1 (de) | 2021-07-05 | 2024-05-15 | Chiesi Farmaceutici S.p.A. | Verfahren zur herstellung eines lungensurfactants |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS55160721A (en) * | 1979-06-02 | 1980-12-13 | Tokyo Tanabe Co Ltd | Pulmonary surfactant ta-546, its preparation, and remedy for pulmonary hyaline membrane syndrome comprising it as active constituent |
| JPS5845299A (ja) * | 1981-09-10 | 1983-03-16 | 東京田辺製薬株式会社 | 新規な表面活性物質、その製造法及びそれを含有する呼吸窮迫疾候群治療剤 |
| JPS59164724A (ja) * | 1983-03-10 | 1984-09-17 | Tokyo Tanabe Co Ltd | サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤 |
| FR2586587B1 (fr) * | 1985-08-30 | 1987-10-23 | Adir | Nouveaux surfactants artificiels, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| US5013720A (en) * | 1986-05-06 | 1991-05-07 | Abbott Laboratories | SAP-6-Val proteins and methods |
| IT1203873B (it) * | 1987-04-08 | 1989-02-23 | Chiesi Farma Spa | Composizioni farmaceutiche che lo surfattante polmonare naturale, contengono. metodo di preparazione e |
| US5164369A (en) * | 1988-01-06 | 1992-11-17 | The Scripps Research Institute | Pulmonary surfactant protein and related polypeptide |
| DE3921954A1 (de) * | 1989-07-04 | 1991-01-17 | Thomae Gmbh Dr K | Niedrig-viskose, hochkonzentrierte surfactant-suspension |
| GB9021080D0 (en) * | 1990-09-26 | 1990-11-07 | Univ Western Ontario | Lipid extract surfactant and method of producing same |
-
1995
- 1995-06-07 US US08/475,539 patent/US6129934A/en not_active Expired - Lifetime
-
1996
- 1996-06-05 CA CA002221625A patent/CA2221625A1/en not_active Abandoned
- 1996-06-05 AU AU58868/96A patent/AU5886896A/en not_active Abandoned
- 1996-06-05 WO PCT/US1996/008828 patent/WO1996040177A1/en not_active Ceased
- 1996-06-05 AT AT96920616T patent/ATE274914T1/de not_active IP Right Cessation
- 1996-06-05 DE DE69633279T patent/DE69633279D1/de not_active Expired - Lifetime
- 1996-06-05 EP EP96920616A patent/EP0831862B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0831862A1 (de) | 1998-04-01 |
| US6129934A (en) | 2000-10-10 |
| DE69633279D1 (de) | 2004-10-07 |
| CA2221625A1 (en) | 1996-12-19 |
| WO1996040177A1 (en) | 1996-12-19 |
| EP0831862B1 (de) | 2004-09-01 |
| AU5886896A (en) | 1996-12-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |