ATE275403T1 - Kalziumsalze von 1,5-benzodiazepin-derivaten, verfahren zu deren herstellung und diese enthaltende medikamente - Google Patents

Kalziumsalze von 1,5-benzodiazepin-derivaten, verfahren zu deren herstellung und diese enthaltende medikamente

Info

Publication number
ATE275403T1
ATE275403T1 AT00979047T AT00979047T ATE275403T1 AT E275403 T1 ATE275403 T1 AT E275403T1 AT 00979047 T AT00979047 T AT 00979047T AT 00979047 T AT00979047 T AT 00979047T AT E275403 T1 ATE275403 T1 AT E275403T1
Authority
AT
Austria
Prior art keywords
calcium salts
production
containing same
benzodiazepine derivatives
medications containing
Prior art date
Application number
AT00979047T
Other languages
English (en)
Inventor
Katsuo Shinozaki
Masakazu Murata
Kiyoto Maeda
Hiroaki Taguchi
Nobuo Kawase
Naoyoshi Miura
Original Assignee
Zeria Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zeria Pharm Co Ltd filed Critical Zeria Pharm Co Ltd
Application granted granted Critical
Publication of ATE275403T1 publication Critical patent/ATE275403T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
AT00979047T 1999-12-02 2000-12-01 Kalziumsalze von 1,5-benzodiazepin-derivaten, verfahren zu deren herstellung und diese enthaltende medikamente ATE275403T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP34279999 1999-12-02
PCT/JP2000/008511 WO2001040197A1 (en) 1999-12-02 2000-12-01 Calcium salts of 1,5-benzodiazepine derivatives, process for producing the salts and drugs containing the same

Publications (1)

Publication Number Publication Date
ATE275403T1 true ATE275403T1 (de) 2004-09-15

Family

ID=18356597

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00979047T ATE275403T1 (de) 1999-12-02 2000-12-01 Kalziumsalze von 1,5-benzodiazepin-derivaten, verfahren zu deren herstellung und diese enthaltende medikamente

Country Status (13)

Country Link
US (1) US6747022B2 (de)
EP (1) EP1234818B1 (de)
JP (1) JP3922024B2 (de)
KR (1) KR100753005B1 (de)
CN (1) CN1221538C (de)
AT (1) ATE275403T1 (de)
AU (1) AU776283B2 (de)
CA (1) CA2392057C (de)
DE (1) DE60013639T2 (de)
ES (1) ES2228633T3 (de)
PT (1) PT1234818E (de)
TW (1) TWI288747B (de)
WO (1) WO2001040197A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100481894C (zh) * 2000-08-28 2009-04-22 索尼电子有限公司 用于交互式电视的系统
CN101098854B (zh) 2004-07-23 2012-12-05 恩多塞特公司 二价连接体及其轭合物
PL1839662T3 (pl) * 2005-01-19 2010-08-31 Zeria Pharm Co Ltd Środek przeciwnowotworowy
BRPI0812970A2 (pt) 2007-06-25 2019-09-24 Endocyte Inc conjugados contendo espaçadores hidrofílicos
US9877965B2 (en) 2007-06-25 2018-01-30 Endocyte, Inc. Vitamin receptor drug delivery conjugates for treating inflammation
TWI459948B (zh) 2008-05-15 2014-11-11 Zeria Pharm Co Ltd The use of a 1,5-benzodiazepine derivative or a pharmaceutically acceptable salt thereof for the manufacture of a pain therapeutic agent composition
CN102333763A (zh) 2009-03-31 2012-01-25 善利亚新药工业股份有限公司 1,5-苯二氮䓬衍生物的制备方法
WO2013126797A1 (en) 2012-02-24 2013-08-29 Purdue Research Foundation Cholecystokinin b receptor targeting for imaging and therapy
CN104604880A (zh) * 2014-12-31 2015-05-13 江阴苏利化学股份有限公司 一种含有氮杂卓的防治甘蓝蚜虫的农药组合物
JP2019131467A (ja) * 2016-04-08 2019-08-08 ゼリア新薬工業株式会社 １，５−ベンゾジアゼピン化合物の結晶
JP2019167295A (ja) * 2016-07-04 2019-10-03 ゼリア新薬工業株式会社 １，５−ベンゾジアゼピン化合物カルシウム塩の製造法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1332410C (en) 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
RU94046297A (ru) 1992-06-24 1996-11-27 Яманоути Фармасьютикал Ко. Новое бензодиазепиновое производное, способ его получения фармкомпозиция
DE69430068T2 (de) 1993-12-28 2002-08-14 SHIONOGI & CO., LTD. Benzodiazepinderivate
JP3999819B2 (ja) * 1996-12-10 2007-10-31 ゼリア新薬工業株式会社 １，５―ベンゾジアセピン誘導体
JP2000026434A (ja) 1998-06-05 2000-01-25 Zeria Pharmaceut Co Ltd 新規１，５−ベンゾジアゼピン誘導体

Also Published As

Publication number Publication date
EP1234818A4 (de) 2002-11-06
AU1650301A (en) 2001-06-12
EP1234818B1 (de) 2004-09-08
US20030096809A1 (en) 2003-05-22
CN1409706A (zh) 2003-04-09
EP1234818A1 (de) 2002-08-28
AU776283B2 (en) 2004-09-02
KR100753005B1 (ko) 2007-08-30
DE60013639D1 (de) 2004-10-14
TWI288747B (en) 2007-10-21
KR20020058038A (ko) 2002-07-12
CA2392057A1 (en) 2001-06-07
DE60013639T2 (de) 2005-02-03
PT1234818E (pt) 2005-01-31
WO2001040197A1 (en) 2001-06-07
JP3922024B2 (ja) 2007-05-30
CN1221538C (zh) 2005-10-05
US6747022B2 (en) 2004-06-08
CA2392057C (en) 2009-10-27
ES2228633T3 (es) 2005-04-16

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