ATE275585T1 - Heteropolysaccharid-konjugate, halbinterpenetrierende polysaccharidgele und verfahren zu deren herstellung - Google Patents
Heteropolysaccharid-konjugate, halbinterpenetrierende polysaccharidgele und verfahren zu deren herstellungInfo
- Publication number
- ATE275585T1 ATE275585T1 AT98920055T AT98920055T ATE275585T1 AT E275585 T1 ATE275585 T1 AT E275585T1 AT 98920055 T AT98920055 T AT 98920055T AT 98920055 T AT98920055 T AT 98920055T AT E275585 T1 ATE275585 T1 AT E275585T1
- Authority
- AT
- Austria
- Prior art keywords
- alginate
- glycosaminoglycan
- cross
- polymerized
- linked
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000004676 glycans Chemical class 0.000 title 1
- 229920001282 polysaccharide Polymers 0.000 title 1
- 239000005017 polysaccharide Substances 0.000 title 1
- FHVDTGUDJYJELY-UHFFFAOYSA-N 6-{[2-carboxy-4,5-dihydroxy-6-(phosphanyloxy)oxan-3-yl]oxy}-4,5-dihydroxy-3-phosphanyloxane-2-carboxylic acid Chemical compound O1C(C(O)=O)C(P)C(O)C(O)C1OC1C(C(O)=O)OC(OP)C(O)C1O FHVDTGUDJYJELY-UHFFFAOYSA-N 0.000 abstract 5
- 229920002683 Glycosaminoglycan Polymers 0.000 abstract 5
- 229940072056 alginate Drugs 0.000 abstract 5
- 235000010443 alginic acid Nutrition 0.000 abstract 5
- 229920000615 alginic acid Polymers 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 5
- 239000000499 gel Substances 0.000 abstract 4
- 159000000007 calcium salts Chemical class 0.000 abstract 2
- 238000005859 coupling reaction Methods 0.000 abstract 2
- -1 e.g. Chemical compound 0.000 abstract 2
- 229910017053 inorganic salt Inorganic materials 0.000 abstract 2
- IXPNQXFRVYWDDI-UHFFFAOYSA-N 1-methyl-2,4-dioxo-1,3-diazinane-5-carboximidamide Chemical compound CN1CC(C(N)=N)C(=O)NC1=O IXPNQXFRVYWDDI-UHFFFAOYSA-N 0.000 abstract 1
- 239000011324 bead Substances 0.000 abstract 1
- 238000004132 cross linking Methods 0.000 abstract 1
- 239000003094 microcapsule Substances 0.000 abstract 1
- 239000003973 paint Substances 0.000 abstract 1
- 230000000379 polymerizing effect Effects 0.000 abstract 1
- 235000010413 sodium alginate Nutrition 0.000 abstract 1
- 229940005550 sodium alginate Drugs 0.000 abstract 1
- 239000000661 sodium alginate Substances 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
- A61L17/14—Post-treatment to improve physical properties
- A61L17/145—Coating
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/04—Alginic acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Botany (AREA)
- Vascular Medicine (AREA)
- Zoology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Surgery (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Colloid Chemistry (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4511197P | 1997-04-30 | 1997-04-30 | |
| US08/877,682 US6281341B1 (en) | 1997-04-30 | 1997-06-17 | Hetero-polysaccharide conjugate and methods of making and using the same |
| PCT/US1998/008752 WO1998049202A1 (en) | 1997-04-30 | 1998-04-30 | NOVEL HETERO-POLYSACCHARIDE CONJUGATES, NOVEL s-INP POLYSACCHARIDE GELS AND METHODS OF MAKING AND USING THE SAME |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE275585T1 true ATE275585T1 (de) | 2004-09-15 |
Family
ID=26722388
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98920055T ATE275585T1 (de) | 1997-04-30 | 1998-04-30 | Heteropolysaccharid-konjugate, halbinterpenetrierende polysaccharidgele und verfahren zu deren herstellung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6281341B1 (de) |
| EP (1) | EP0977780B1 (de) |
| AT (1) | ATE275585T1 (de) |
| BR (1) | BR9809326A (de) |
| DE (1) | DE69826119T2 (de) |
| WO (1) | WO1998049202A1 (de) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6958148B1 (en) | 1998-01-20 | 2005-10-25 | Pericor Science, Inc. | Linkage of agents to body tissue using microparticles and transglutaminase |
| US6919076B1 (en) | 1998-01-20 | 2005-07-19 | Pericor Science, Inc. | Conjugates of agents and transglutaminase substrate linking molecules |
| DE60026974T2 (de) * | 1999-01-04 | 2007-04-19 | Biomm, Inc., Miami | Neue polymerformulierungen, die perfluorierte verbindungen enthalten, zum konstruieren von zellen und geweben zur transplantation, welche den stoffwechsel und das überleben von zellen verbessern, sowie verfahren zu deren herstellung |
| EP2428563A1 (de) | 2005-02-10 | 2012-03-14 | Regents Of The University Of Minnesota | Vaskuläre/Lymphatische Endothelzellen |
| FR2925316B1 (fr) * | 2007-12-21 | 2010-02-12 | Oreal | Kit comprenant un alginate et un agent de complexation sous forme de sel insoluble dans l'eau |
| FR2925306B1 (fr) * | 2007-12-21 | 2010-03-05 | Oreal | Kit pour la peau et les levres comprenant un alginate et un agent de complexation |
| FR2925310B1 (fr) * | 2007-12-21 | 2010-03-05 | Oreal | Kit de mascara comprenant un alginate et un agent de complexation |
| FR2925315B1 (fr) * | 2007-12-21 | 2010-02-12 | Oreal | Kit comprenant un alginate et un agent de complexation sous forme de sel hydrosoluble |
| WO2009108760A2 (en) | 2008-02-26 | 2009-09-03 | Board Of Regents, The University Of Texas System | Dendritic macroporous hydrogels prepared by crystal templating |
| EP2196196A1 (de) * | 2008-12-10 | 2010-06-16 | Medipol S.A. | Verbindung, Medikament, Impfstoff und Nanokapseln |
| CN101570582B (zh) * | 2009-05-26 | 2011-07-20 | 中山大学附属第一医院 | 一种具有水溶性和生物降解性的电活性聚合物及其制备方法和应用 |
| US9085757B2 (en) | 2010-06-17 | 2015-07-21 | Regents Of The University Of Minnesota | Production of insulin producing cells |
| WO2012048283A1 (en) | 2010-10-08 | 2012-04-12 | Board Of Regents, The University Of Texas System | One-step processing of hydrogels for mechanically robust and chemically desired features |
| US9095558B2 (en) | 2010-10-08 | 2015-08-04 | Board Of Regents, The University Of Texas System | Anti-adhesive barrier membrane using alginate and hyaluronic acid for biomedical applications |
| WO2013071216A1 (en) * | 2011-11-11 | 2013-05-16 | Miba Medical Inc. | Injectable filler |
| EP2892541B1 (de) | 2012-09-04 | 2021-04-21 | Technion Research & Development Foundation Limited | Verwendung einer dezellularisierten extrazellulären matrix zur zellenverkapselung |
| MX375019B (es) | 2012-12-11 | 2025-03-06 | Univ Texas | Membrana de hidrogel para prevención de la adhesión. |
| FI129934B (en) | 2015-02-13 | 2022-11-15 | Upm Kymmene Corp | Sewing thread, method of making sewing thread and its use |
| MA46426A (fr) | 2016-09-16 | 2019-07-24 | Glycologix Llc | Biomatériaux à base de glycosaminoglycanes sulfatés utilisés en tant que mimétiques de protéoglycanes |
| WO2018165327A1 (en) | 2017-03-08 | 2018-09-13 | Alafair Biosciences, Inc. | Hydrogel medium for the storage and preservation of tissue |
| CN116710110A (zh) | 2020-12-28 | 2023-09-05 | 持田制药株式会社 | 新型的多层聚合物涂层交联海藻酸凝胶纤维 |
| US20240342340A1 (en) | 2020-12-28 | 2024-10-17 | Mochida Pharmaceutical Co., Ltd. | Multilayer structure using chemically crosslinked alginic acid |
| CN117089332A (zh) * | 2023-07-05 | 2023-11-21 | 西南石油大学 | 一种环境友好的酸化用互穿网络凝胶暂堵剂及制备方法 |
| WO2025252718A1 (en) | 2024-06-04 | 2025-12-11 | Chemetall Gmbh | Amino acid-based copolymer comprising composition for use in chemical pretreatment of metallic substrates |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4409331A (en) * | 1979-03-28 | 1983-10-11 | Damon Corporation | Preparation of substances with encapsulated cells |
| US5129877A (en) * | 1988-04-29 | 1992-07-14 | University Of Georgia Research Foundation, Inc. | Receptor-mediated delivery system |
| FR2636339B1 (fr) * | 1988-09-09 | 1992-07-17 | Auge Pier | Gel aqueux a base d'acide hyaluronique et d'acide desoxyribonucleique utilisable en cosmetique, et procede de preparation |
| FR2652741B1 (fr) * | 1989-10-10 | 1994-03-04 | Laboratoires Care System | Composition antimicrobienne pour application sur la peau, applications comme deodorant corporel et bactericide cutane. |
| US5084350A (en) * | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
| IT1248666B (it) * | 1990-05-30 | 1995-01-26 | Fidia Spa | Gel in forma di film autosupportanti altamente idrati, processo per laloro preparazione e impiego nella terapia di lesioni e/o patologie cutanee |
| GB9320232D0 (en) | 1993-10-01 | 1993-11-17 | C V Lab Ltd | Alginate wound dressing |
-
1997
- 1997-06-17 US US08/877,682 patent/US6281341B1/en not_active Expired - Fee Related
-
1998
- 1998-04-30 BR BR9809326-6A patent/BR9809326A/pt not_active Application Discontinuation
- 1998-04-30 AT AT98920055T patent/ATE275585T1/de not_active IP Right Cessation
- 1998-04-30 DE DE69826119T patent/DE69826119T2/de not_active Expired - Fee Related
- 1998-04-30 EP EP98920055A patent/EP0977780B1/de not_active Expired - Lifetime
- 1998-04-30 WO PCT/US1998/008752 patent/WO1998049202A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0977780A4 (de) | 2002-02-27 |
| EP0977780A1 (de) | 2000-02-09 |
| DE69826119T2 (de) | 2005-09-15 |
| US6281341B1 (en) | 2001-08-28 |
| BR9809326A (pt) | 2000-07-04 |
| WO1998049202A1 (en) | 1998-11-05 |
| DE69826119D1 (de) | 2004-10-14 |
| EP0977780B1 (de) | 2004-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0977780 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |