ATE276234T1 - Harnstoffderivate zur schmerzbekämpfung - Google Patents

Harnstoffderivate zur schmerzbekämpfung

Info

Publication number
ATE276234T1
ATE276234T1 AT99931710T AT99931710T ATE276234T1 AT E276234 T1 ATE276234 T1 AT E276234T1 AT 99931710 T AT99931710 T AT 99931710T AT 99931710 T AT99931710 T AT 99931710T AT E276234 T1 ATE276234 T1 AT E276234T1
Authority
AT
Austria
Prior art keywords
fighting
pain
urea derivatives
urea
derivatives
Prior art date
Application number
AT99931710T
Other languages
English (en)
Inventor
Daniel Methylgene Inc Delorme
Vlad Gregor
Edward Roberts
Eric Alanex Corp Sun
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE276234T1 publication Critical patent/ATE276234T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0446—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT99931710T 1998-06-22 1999-06-16 Harnstoffderivate zur schmerzbekämpfung ATE276234T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9802209A SE9802209D0 (sv) 1998-06-22 1998-06-22 Novel compounds
PCT/SE1999/001075 WO1999067204A1 (en) 1998-06-22 1999-06-16 Novel compounds

Publications (1)

Publication Number Publication Date
ATE276234T1 true ATE276234T1 (de) 2004-10-15

Family

ID=20411787

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99931710T ATE276234T1 (de) 1998-06-22 1999-06-16 Harnstoffderivate zur schmerzbekämpfung

Country Status (11)

Country Link
US (2) US6777561B1 (de)
EP (1) EP1089965B1 (de)
AR (1) AR029302A1 (de)
AT (1) ATE276234T1 (de)
AU (1) AU4814699A (de)
CA (1) CA2335528A1 (de)
DE (1) DE69920224T2 (de)
ES (1) ES2228066T3 (de)
PT (1) PT1089965E (de)
SE (1) SE9802209D0 (de)
WO (1) WO1999067204A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69926806D1 (de) * 1998-12-18 2005-09-22 Bristol Myers Squibb Pharma Co N-ureidoalkylpiperidine als modulatoren der aktivität der chemokinrezeptoren
WO2000035449A1 (en) * 1998-12-18 2000-06-22 Du Pont Pharmaceuticals Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6525069B1 (en) 1998-12-18 2003-02-25 Bristol-Myers Squibb Pharma Co. N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6331541B1 (en) 1998-12-18 2001-12-18 Soo S. Ko N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6492400B1 (en) 1998-12-18 2002-12-10 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6897234B2 (en) 1999-12-17 2005-05-24 Bristol-Myers Squibb Pharma Company N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
JP2004516238A (ja) * 2000-06-21 2004-06-03 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー ケモカイン受容体活性調節剤としてのｎ−ウレイドアルキル−ピペリジン
JP2004517805A (ja) 2000-06-30 2004-06-17 ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー ケモカイン受容体活性調節剤としてのｎ−ウレイドヘテロシクロアルキル−ピペリジン
US7332514B2 (en) 2002-08-30 2008-02-19 Japan Tobacco Inc. Dibenzylamine compound and medicinal use thereof
KR101025633B1 (ko) 2002-09-19 2011-03-30 일라이 릴리 앤드 캄파니 오피오이드 수용체 안타고니스트로서의 디아릴 에테르
RS53347B (sr) * 2008-12-09 2014-10-31 Gilead Sciences, Inc. Modulatori toll-sličnih receptora

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH441366A (de) 1961-06-09 1967-08-15 Hoffmann La Roche Verfahren zur Herstellung von substituierten Hydrazinverbindungen
NL7800026A (nl) * 1977-01-07 1978-07-11 Acna Werkwijze voor de bereiding van gesubstitueerde amino-benzenen.
DE3483308D1 (de) 1983-11-21 1990-10-31 Fujisawa Pharmaceutical Co Semicarbazid-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
CN1021819C (zh) * 1988-01-20 1993-08-18 山之内制药株式会社 作为药物有用的双脲衍生物的制备方法
TW209868B (de) 1991-04-04 1993-07-21 Yoshitomi Pharmaceutical
GB9511355D0 (en) * 1995-06-06 1995-08-02 Fujisawa Pharmaceutical Co Urea derivatives
DE19544687A1 (de) * 1995-11-30 1997-06-05 Thomae Gmbh Dr K Aminosäurederivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
US5770615A (en) 1996-04-04 1998-06-23 Bristol-Myers Squibb Company Catecholamine surrogates useful as β3 agonists
US5866609A (en) 1996-08-09 1999-02-02 Ss Pharmaceutical Co., Ltd. Substituted vinylurea derivatives and medicine containing the same
DE69826695T2 (de) 1997-05-23 2006-02-02 Bayer Pharmaceuticals Corp., West Haven Arylharnstoffderivate zur behandlung von inflammatorischen oder immunomodulatorischen erkrankungen

Also Published As

Publication number Publication date
WO1999067204A1 (en) 1999-12-29
AU4814699A (en) 2000-01-10
US20050032789A1 (en) 2005-02-10
DE69920224D1 (de) 2004-10-21
EP1089965A1 (de) 2001-04-11
EP1089965B1 (de) 2004-09-15
DE69920224T2 (de) 2005-10-13
US6777561B1 (en) 2004-08-17
AR029302A1 (es) 2003-06-25
PT1089965E (pt) 2004-12-31
CA2335528A1 (en) 1999-12-29
ES2228066T3 (es) 2005-04-01
SE9802209D0 (sv) 1998-06-22

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