ATE277024T1 - Verfahren zur herstellung eines 4- thiazolylmethylderivates - Google Patents

Verfahren zur herstellung eines 4- thiazolylmethylderivates

Info

Publication number
ATE277024T1
ATE277024T1 AT99906538T AT99906538T ATE277024T1 AT E277024 T1 ATE277024 T1 AT E277024T1 AT 99906538 T AT99906538 T AT 99906538T AT 99906538 T AT99906538 T AT 99906538T AT E277024 T1 ATE277024 T1 AT E277024T1
Authority
AT
Austria
Prior art keywords
thiazolylmethyl
derivative
producing
halogen
production
Prior art date
Application number
AT99906538T
Other languages
English (en)
Inventor
Masaaki Uenaka
Masahiko Nagai
Naotake Kobayashi
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE277024T1 publication Critical patent/ATE277024T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT99906538T 1998-03-02 1999-03-01 Verfahren zur herstellung eines 4- thiazolylmethylderivates ATE277024T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4925998 1998-03-02
PCT/JP1999/000975 WO1999045000A1 (en) 1998-03-02 1999-03-01 Process for producing 4-thiazolylmethyl derivative

Publications (1)

Publication Number Publication Date
ATE277024T1 true ATE277024T1 (de) 2004-10-15

Family

ID=12825843

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99906538T ATE277024T1 (de) 1998-03-02 1999-03-01 Verfahren zur herstellung eines 4- thiazolylmethylderivates

Country Status (9)

Country Link
US (1) US6506903B1 (de)
EP (1) EP1069118B1 (de)
JP (1) JP3811885B2 (de)
AT (1) ATE277024T1 (de)
AU (1) AU2642399A (de)
DE (1) DE69920423T2 (de)
ES (1) ES2229680T3 (de)
TW (1) TW530052B (de)
WO (1) WO1999045000A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2383300C (en) * 1999-08-30 2012-01-24 Shionogi & Co., Ltd. Processes for the preparation of oxo-oxazoline or alloamino acid derivatives
TWI285110B (en) * 2000-08-31 2007-08-11 Shionogi & Co Parkinson disease therapeutic agent
CN101903010B (zh) 2007-12-19 2014-11-26 雅芳产品公司 含有非成蛋白质性氨基酸的局部组合物以及治疗皮肤的方法
JP5981719B2 (ja) * 2009-06-08 2016-08-31 株式会社カネカ 光学活性チアゾリルアラニン誘導体およびその塩の製造方法
CN118028395B (zh) * 2023-12-26 2025-11-28 中国科学院青岛生物能源与过程研究所 一种生物酶法合成(s)-2-氨基-3-(噻唑-4-基)丙酸的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3886467T2 (de) * 1987-08-01 1994-06-01 Takeda Chemical Industries Ltd Alpha-ungesättigte Amine, ihre Herstellung und Verwendung.
US5275950A (en) 1990-05-11 1994-01-04 Abbott Laboratories Process for the preparation of a renin inhibiting compound
US5492916A (en) * 1993-12-23 1996-02-20 Merck & Co., Inc. Di- and tri-substituted piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone
US5459274A (en) 1994-05-13 1995-10-17 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-alkyl-N-pyridinyl-1H-indol-1-amines
WO1998008867A1 (en) 1996-08-28 1998-03-05 Shionogi & Co., Ltd. Novel peptide derivatives having thiazolyl-alanine residue

Also Published As

Publication number Publication date
AU2642399A (en) 1999-09-20
WO1999045000A1 (en) 1999-09-10
ES2229680T3 (es) 2005-04-16
TW530052B (en) 2003-05-01
EP1069118B1 (de) 2004-09-22
US6506903B1 (en) 2003-01-14
EP1069118A4 (de) 2002-06-05
DE69920423T2 (de) 2006-02-23
EP1069118A1 (de) 2001-01-17
DE69920423D1 (de) 2004-10-28
JP3811885B2 (ja) 2006-08-23

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties