ATE278029T1 - Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression - Google Patents

Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Info

Publication number
ATE278029T1
ATE278029T1 AT99903600T AT99903600T ATE278029T1 AT E278029 T1 ATE278029 T1 AT E278029T1 AT 99903600 T AT99903600 T AT 99903600T AT 99903600 T AT99903600 T AT 99903600T AT E278029 T1 ATE278029 T1 AT E278029T1
Authority
AT
Austria
Prior art keywords
gene expression
vector
promoter
coding sequence
retroviral vector
Prior art date
Application number
AT99903600T
Other languages
English (en)
Inventor
Walter Guenzburg
Dieter Klein
Walter Tabotta
Brian Salmons
Original Assignee
Inst Virologie Teilrechtsfaehi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Virologie Teilrechtsfaehi filed Critical Inst Virologie Teilrechtsfaehi
Application granted granted Critical
Publication of ATE278029T1 publication Critical patent/ATE278029T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99903600T 1998-01-06 1999-01-03 Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression ATE278029T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK598 1998-01-06
PCT/EP1999/000002 WO1999035280A1 (en) 1998-01-06 1999-01-03 Reconstituting retroviral vector (recon vector) for targeted gene expression

Publications (1)

Publication Number Publication Date
ATE278029T1 true ATE278029T1 (de) 2004-10-15

Family

ID=8088665

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99903600T ATE278029T1 (de) 1998-01-06 1999-01-03 Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Country Status (7)

Country Link
US (1) US6821776B1 (de)
EP (1) EP1045922B1 (de)
AT (1) ATE278029T1 (de)
AU (1) AU2419599A (de)
DE (1) DE69920659T2 (de)
ES (1) ES2229674T3 (de)
WO (1) WO1999035280A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69627644T2 (de) 1995-03-09 2004-02-19 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
US7101541B2 (en) 2000-05-19 2006-09-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Utilization of non-viral sequences for minus-strand DNA transfer and gene reconstitution
JP2004535151A (ja) * 2000-10-10 2004-11-25 インスティトゥート フューア ヴィロロギー タイルレヒツフェヒゲス インスティトゥート アン デア ヴェテリネーアメディツィニーシェン ウニヴェルズィテート ヴィーン ウイルス性成分の活性および／または特異性の評価に対する新システム
DE10292896D2 (de) * 2001-07-05 2004-07-01 Univ Goettingen Georg August Gentherapeutisches Verfahren zur Behandlung von GnRH-Rezeptor-positiven Karzinomen durch GnRH induzierte tumorzellspezifische Aktivierung eines therapeutischen Gens, zugehörige Nukleinsäurekonstrukte und Vektoren
EP1273309A1 (de) * 2001-07-05 2003-01-08 Georg-August Universität Göttingen Gentherapeutisches Verfahren zur Behandlung von GnRH-Rezeptor-positiven Karzinomen durch GnRH induzierte tumorzellspezifische Aktivierung eines therapeutischen Gens, zugehörige Nukleinsäurekonstrukte und Vektoren
US20090214496A1 (en) * 2006-01-30 2009-08-27 Licentia Ltd. Bmx/etk tyrosine kinase gene therapy materials and methods
MX2017017062A (es) * 2015-07-01 2018-09-05 The Regents Of Univ Of California Vectores retrovirales que contienen un promotor de ubiquitina c humana de orientacion inversa.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011539A1 (en) * 1988-05-17 1989-11-30 Sloan-Kettering Institute For Cancer Research Retroviral vector
US5658775A (en) 1988-05-17 1997-08-19 Sloan-Kettering Institute For Cancer Research Double copy retroviral vector
RU2199585C2 (ru) * 1994-09-02 2003-02-27 ГСФ-Форшунгсцентрум фюр Умвельт унд Гезундхайт ГмбХ Ретровирусная векторная конструкция, подвергающаяся промоторной конверсии, способ введения гомологичных или гетерологичных нуклеотидных последовательностей в человеческие или животные клетки in vitro и/или in vivo, рекомбинантная ретровирусная частица, фармацевтическая композиция для генной терапии
DE69627644T2 (de) * 1995-03-09 2004-02-19 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
EP0848757B1 (de) 1995-09-06 2002-03-06 Austrian Nordic Biotherapeutics AG Expression von heterologen genen in menschlichen brustzellen, einschliesslich menschliche brustkarzionomzellen unter der kontrolle von regulatorischen sequenzen von wap oder mmtv

Also Published As

Publication number Publication date
AU2419599A (en) 1999-07-26
US6821776B1 (en) 2004-11-23
WO1999035280A1 (en) 1999-07-15
EP1045922B1 (de) 2004-09-29
ES2229674T3 (es) 2005-04-16
DE69920659T2 (de) 2006-03-09
DE69920659D1 (de) 2004-11-04
EP1045922A1 (de) 2000-10-25

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