ATE278029T1 - Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression - Google Patents

Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Info

Publication number
ATE278029T1
ATE278029T1 AT99903600T AT99903600T ATE278029T1 AT E278029 T1 ATE278029 T1 AT E278029T1 AT 99903600 T AT99903600 T AT 99903600T AT 99903600 T AT99903600 T AT 99903600T AT E278029 T1 ATE278029 T1 AT E278029T1
Authority
AT
Austria
Prior art keywords
gene expression
vector
promoter
coding sequence
retroviral vector
Prior art date
Application number
AT99903600T
Other languages
English (en)
Inventor
Walter Guenzburg
Dieter Klein
Walter Tabotta
Brian Salmons
Original Assignee
Inst Virologie Teilrechtsfaehi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Virologie Teilrechtsfaehi filed Critical Inst Virologie Teilrechtsfaehi
Application granted granted Critical
Publication of ATE278029T1 publication Critical patent/ATE278029T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99903600T 1998-01-06 1999-01-03 Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression ATE278029T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK598 1998-01-06
PCT/EP1999/000002 WO1999035280A1 (en) 1998-01-06 1999-01-03 Reconstituting retroviral vector (recon vector) for targeted gene expression

Publications (1)

Publication Number Publication Date
ATE278029T1 true ATE278029T1 (de) 2004-10-15

Family

ID=8088665

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99903600T ATE278029T1 (de) 1998-01-06 1999-01-03 Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Country Status (7)

Country Link
US (1) US6821776B1 (de)
EP (1) EP1045922B1 (de)
AT (1) ATE278029T1 (de)
AU (1) AU2419599A (de)
DE (1) DE69920659T2 (de)
ES (1) ES2229674T3 (de)
WO (1) WO1999035280A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996028563A1 (en) 1995-03-09 1996-09-19 Bavarian Nordic Vectors carrying therapeutic genes encoding antimicrobial peptides for gene therapy
WO2001090391A2 (en) 2000-05-19 2001-11-29 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Utilization of non-viral sequences for minus-strand dna transfer and gene reconstitution
EP1341558A2 (de) * 2000-10-10 2003-09-10 Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien System für die auswertung der aktivität und/oder spezifität einer viraler komponente
EP1273309A1 (de) * 2001-07-05 2003-01-08 Georg-August Universität Göttingen Gentherapeutisches Verfahren zur Behandlung von GnRH-Rezeptor-positiven Karzinomen durch GnRH induzierte tumorzellspezifische Aktivierung eines therapeutischen Gens, zugehörige Nukleinsäurekonstrukte und Vektoren
DE10292896D2 (de) * 2001-07-05 2004-07-01 Univ Goettingen Georg August Gentherapeutisches Verfahren zur Behandlung von GnRH-Rezeptor-positiven Karzinomen durch GnRH induzierte tumorzellspezifische Aktivierung eines therapeutischen Gens, zugehörige Nukleinsäurekonstrukte und Vektoren
WO2007089780A2 (en) * 2006-01-30 2007-08-09 Licentia, Ltd. Bmx/etk tyrosine kinase gene therapy materials and methods
PE20180772A1 (es) * 2015-07-01 2018-05-07 Univ California Vectores retrovirales que contienen un promotor de ubiquitina c humana de orientacion inversa

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02504344A (ja) * 1988-05-17 1990-12-13 スローン‐ケツテリング・インステイテユート・フオー・キヤンサー・リサーチ レトロウイルスベクター
US5658775A (en) 1988-05-17 1997-08-19 Sloan-Kettering Institute For Cancer Research Double copy retroviral vector
JP4037446B2 (ja) * 1994-09-02 2008-01-23 ゲーエスエフ − フォルシュンクスツェントルム・フューア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー 非自己不活化性の発現標的化レトロウイルスベクタ
WO1996028563A1 (en) * 1995-03-09 1996-09-19 Bavarian Nordic Vectors carrying therapeutic genes encoding antimicrobial peptides for gene therapy
JPH11511979A (ja) 1995-09-06 1999-10-19 ババリアン・ノルディック・リサーチ・インスティテュート・アクティーゼルスカブ ヒト乳癌細胞を含むヒト乳腺細胞を標的として、連結された異種性遺伝子を発現させるためのｗａｐまたはｍｍｔｖ制御配列の使用

Also Published As

Publication number Publication date
ES2229674T3 (es) 2005-04-16
EP1045922B1 (de) 2004-09-29
DE69920659D1 (de) 2004-11-04
AU2419599A (en) 1999-07-26
EP1045922A1 (de) 2000-10-25
US6821776B1 (en) 2004-11-23
WO1999035280A1 (en) 1999-07-15
DE69920659T2 (de) 2006-03-09

Similar Documents

Publication Publication Date Title
Ohkawa et al. Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus.
FI951404A0 (fi) Adenovirusvektoreita vieraiden geenien siirtämiseksi keskushermostojärjestelmän, erityisesti aivojen, soluihin
IL110182A0 (en) Retroviral carrier for the transference and introduction of genes for therapeutic aims into eukaryotic cells
DE69830663D1 (de) Nicht-primaten lentivirale vektoren und verpackungssysteme
WO1996037623B1 (en) Retroviral vectors
ATE553205T1 (de) Verwendung von dns-sequenzen mit triplex-structur zum transfer von nukleotidsequenzen
EP0267851A3 (en) Hybrid promoter, expression controlling dna sequence and expression vector
PL319512A1 (en) Viral material and nucleotidic fragments associated with sclerosis multiplex or diagnostic, prophylactic and therapeutic purposes
ATE278029T1 (de) Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression
FI940867L (fi) Ilmentämisrakenteita, jotka sisältävät HIV:iä estäviä antisense- ja muita nukleotidisekvenssejä, retrovirusvektoreita ja näitä sisältäviä yhdistelmäretroviruksia
WO1997022695A3 (fr) Sequences nucleotidiques, proteines, medicaments et agents diagnostiques utiles dans le traitement du cancer
JP4037446B2 (ja) 非自己不活化性の発現標的化レトロウイルスベクタ
DK0630409T3 (da) Defekt-pakkende ikke-onkovirus-vektorer baseret på MPMV
ZA961349B (en) Amplifying sequences vectors comprising these sequences and their uses in compositions for the expression of nucleotide sequences in transfected cells therapeutic and vaccine applications
BR9815285A (pt) Vetores alfavìrus para vacina de paramixovìrus
ATE552887T1 (de) Tumorspezifischer vektor für die gentherapie
WO2002086064A3 (en) Inducible expression of transfected genes
EP1264892A3 (de) Lentivirale Vektoren mit Endothelzellen spezifischen Promotoren
ZA941287B (en) Expression constructs containing HIV inhibitory antisense and other nucleotide sequences, retroviral vectors and recombinant retroviruses containing same.
WO2000053789A3 (de) Retrovirale expressionsvektoren auf der basis von herv-ltr-sequenzen
WO2000078939A3 (de) Vektoren zur gentherapeutischen tumorbehandlung
NO945020L (no) Selv-stabiliserende oligonukleotider som terapeutiske midler

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1045922

Country of ref document: EP

REN Ceased due to non-payment of the annual fee