DE69920659D1 - Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression - Google Patents

Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Info

Publication number
DE69920659D1
DE69920659D1 DE69920659T DE69920659T DE69920659D1 DE 69920659 D1 DE69920659 D1 DE 69920659D1 DE 69920659 T DE69920659 T DE 69920659T DE 69920659 T DE69920659 T DE 69920659T DE 69920659 D1 DE69920659 D1 DE 69920659D1
Authority
DE
Germany
Prior art keywords
gene expression
vector
promoter
coding sequence
retroviral vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69920659T
Other languages
English (en)
Other versions
DE69920659T2 (de
Inventor
Walter Guenzburg
Dieter Klein
Walter Tabotta
Brian Salmons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Original Assignee
Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut fuer Virologie der Veterinaermedizinische Universitaet Wien filed Critical Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Application granted granted Critical
Publication of DE69920659D1 publication Critical patent/DE69920659D1/de
Publication of DE69920659T2 publication Critical patent/DE69920659T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69920659T 1998-01-06 1999-01-03 Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression Expired - Fee Related DE69920659T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK598 1998-01-06
DK598 1998-01-06
PCT/EP1999/000002 WO1999035280A1 (en) 1998-01-06 1999-01-03 Reconstituting retroviral vector (recon vector) for targeted gene expression

Publications (2)

Publication Number Publication Date
DE69920659D1 true DE69920659D1 (de) 2004-11-04
DE69920659T2 DE69920659T2 (de) 2006-03-09

Family

ID=8088665

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69920659T Expired - Fee Related DE69920659T2 (de) 1998-01-06 1999-01-03 Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Country Status (7)

Country Link
US (1) US6821776B1 (de)
EP (1) EP1045922B1 (de)
AT (1) ATE278029T1 (de)
AU (1) AU2419599A (de)
DE (1) DE69920659T2 (de)
ES (1) ES2229674T3 (de)
WO (1) WO1999035280A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69627644T2 (de) 1995-03-09 2004-02-19 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
US7101541B2 (en) 2000-05-19 2006-09-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Utilization of non-viral sequences for minus-strand DNA transfer and gene reconstitution
JP2004535151A (ja) * 2000-10-10 2004-11-25 インスティトゥート フューア ヴィロロギー タイルレヒツフェヒゲス インスティトゥート アン デア ヴェテリネーアメディツィニーシェン ウニヴェルズィテート ヴィーン ウイルス性成分の活性および／または特異性の評価に対する新システム
DE10292896D2 (de) * 2001-07-05 2004-07-01 Univ Goettingen Georg August Gentherapeutisches Verfahren zur Behandlung von GnRH-Rezeptor-positiven Karzinomen durch GnRH induzierte tumorzellspezifische Aktivierung eines therapeutischen Gens, zugehörige Nukleinsäurekonstrukte und Vektoren
EP1273309A1 (de) * 2001-07-05 2003-01-08 Georg-August Universität Göttingen Gentherapeutisches Verfahren zur Behandlung von GnRH-Rezeptor-positiven Karzinomen durch GnRH induzierte tumorzellspezifische Aktivierung eines therapeutischen Gens, zugehörige Nukleinsäurekonstrukte und Vektoren
US20090214496A1 (en) * 2006-01-30 2009-08-27 Licentia Ltd. Bmx/etk tyrosine kinase gene therapy materials and methods
MX2017017062A (es) * 2015-07-01 2018-09-05 The Regents Of Univ Of California Vectores retrovirales que contienen un promotor de ubiquitina c humana de orientacion inversa.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011539A1 (en) * 1988-05-17 1989-11-30 Sloan-Kettering Institute For Cancer Research Retroviral vector
US5658775A (en) 1988-05-17 1997-08-19 Sloan-Kettering Institute For Cancer Research Double copy retroviral vector
RU2199585C2 (ru) * 1994-09-02 2003-02-27 ГСФ-Форшунгсцентрум фюр Умвельт унд Гезундхайт ГмбХ Ретровирусная векторная конструкция, подвергающаяся промоторной конверсии, способ введения гомологичных или гетерологичных нуклеотидных последовательностей в человеческие или животные клетки in vitro и/или in vivo, рекомбинантная ретровирусная частица, фармацевтическая композиция для генной терапии
DE69627644T2 (de) * 1995-03-09 2004-02-19 GSF-Forschungszentrum für Umwelt und Gesundheit GmbH Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
EP0848757B1 (de) 1995-09-06 2002-03-06 Austrian Nordic Biotherapeutics AG Expression von heterologen genen in menschlichen brustzellen, einschliesslich menschliche brustkarzionomzellen unter der kontrolle von regulatorischen sequenzen von wap oder mmtv

Also Published As

Publication number Publication date
AU2419599A (en) 1999-07-26
US6821776B1 (en) 2004-11-23
WO1999035280A1 (en) 1999-07-15
EP1045922B1 (de) 2004-09-29
ES2229674T3 (es) 2005-04-16
DE69920659T2 (de) 2006-03-09
EP1045922A1 (de) 2000-10-25
ATE278029T1 (de) 2004-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee