DE69920659D1 - Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression - Google Patents

Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Info

Publication number
DE69920659D1
DE69920659D1 DE69920659T DE69920659T DE69920659D1 DE 69920659 D1 DE69920659 D1 DE 69920659D1 DE 69920659 T DE69920659 T DE 69920659T DE 69920659 T DE69920659 T DE 69920659T DE 69920659 D1 DE69920659 D1 DE 69920659D1
Authority
DE
Germany
Prior art keywords
gene expression
vector
promoter
coding sequence
retroviral vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69920659T
Other languages
English (en)
Other versions
DE69920659T2 (de
Inventor
Walter Guenzburg
Dieter Klein
Walter Tabotta
Brian Salmons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Original Assignee
Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut fuer Virologie der Veterinaermedizinische Universitaet Wien filed Critical Institut fuer Virologie der Veterinaermedizinische Universitaet Wien
Publication of DE69920659D1 publication Critical patent/DE69920659D1/de
Application granted granted Critical
Publication of DE69920659T2 publication Critical patent/DE69920659T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041—Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69920659T 1998-01-06 1999-01-03 Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression Expired - Fee Related DE69920659T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK598 1998-01-06
DK598 1998-01-06
PCT/EP1999/000002 WO1999035280A1 (en) 1998-01-06 1999-01-03 Reconstituting retroviral vector (recon vector) for targeted gene expression

Publications (2)

Publication Number Publication Date
DE69920659D1 true DE69920659D1 (de) 2004-11-04
DE69920659T2 DE69920659T2 (de) 2006-03-09

Family

ID=8088665

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69920659T Expired - Fee Related DE69920659T2 (de) 1998-01-06 1999-01-03 Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression

Country Status (7)

Country Link
US (1) US6821776B1 (de)
EP (1) EP1045922B1 (de)
AT (1) ATE278029T1 (de)
AU (1) AU2419599A (de)
DE (1) DE69920659T2 (de)
ES (1) ES2229674T3 (de)
WO (1) WO1999035280A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE238427T1 (de) 1995-03-09 2003-05-15 Austrian Nordic Biotherapeutic Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
WO2001090391A2 (en) 2000-05-19 2001-11-29 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Utilization of non-viral sequences for minus-strand dna transfer and gene reconstitution
AU2002218218A1 (en) * 2000-10-10 2002-04-22 Austrian Nordic Biotherapeutics Ag A novel system for the evaluation of the activity and/or specificity of a viral component
EP1273309A1 (de) * 2001-07-05 2003-01-08 Georg-August Universität Göttingen Gentherapeutisches Verfahren zur Behandlung von GnRH-Rezeptor-positiven Karzinomen durch GnRH induzierte tumorzellspezifische Aktivierung eines therapeutischen Gens, zugehörige Nukleinsäurekonstrukte und Vektoren
DE10292896D2 (de) * 2001-07-05 2004-07-01 Univ Goettingen Georg August Gentherapeutisches Verfahren zur Behandlung von GnRH-Rezeptor-positiven Karzinomen durch GnRH induzierte tumorzellspezifische Aktivierung eines therapeutischen Gens, zugehörige Nukleinsäurekonstrukte und Vektoren
WO2007089780A2 (en) * 2006-01-30 2007-08-09 Licentia, Ltd. Bmx/etk tyrosine kinase gene therapy materials and methods
KR20180015751A (ko) * 2015-07-01 2018-02-13 더 리전트 오브 더 유니버시티 오브 캘리포니아 역배향 인간 유비퀴틴 c 프로모터를 함유하는 레트로바이러스 벡터들

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02504344A (ja) * 1988-05-17 1990-12-13 スローン‐ケツテリング・インステイテユート・フオー・キヤンサー・リサーチ レトロウイルスベクター
US5658775A (en) 1988-05-17 1997-08-19 Sloan-Kettering Institute For Cancer Research Double copy retroviral vector
MX9701544A (es) * 1994-09-02 1998-03-31 Gsf Forschungszentrum Umwelt Vectores de expresion retrovirales dirigidos, no autoinactivantes.
ATE238427T1 (de) * 1995-03-09 2003-05-15 Austrian Nordic Biotherapeutic Vektoren, die therapeutische gene fuer antimikrobielle peptide enthalten, zur verwendung in der gentherapie
AU6987696A (en) 1995-09-06 1997-03-27 Bavarian Nordic Research Institute A/S The use of the wap of mmtv regulatory sequences for targeted expression of linked heterologous genes in human mammary cells, including human mammary carcinoma cells

Also Published As

Publication number Publication date
EP1045922B1 (de) 2004-09-29
AU2419599A (en) 1999-07-26
EP1045922A1 (de) 2000-10-25
DE69920659T2 (de) 2006-03-09
WO1999035280A1 (en) 1999-07-15
US6821776B1 (en) 2004-11-23
ATE278029T1 (de) 2004-10-15
ES2229674T3 (es) 2005-04-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee