ATE278651T1 - Verfahren zur herstellung von arylsulfonylchlorid - Google Patents

Verfahren zur herstellung von arylsulfonylchlorid

Info

Publication number: ATE278651T1
Authority: AT; Austria
Prior art keywords: alkyl; reaction; oxadiazol; ester; anhydride
Prior art date: 1997-03-07

Application number

AT98908219T

Other languages

English (en)

Inventor

Philip John Hogan

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-07

Filing date

1998-03-03

Publication date

2004-10-15

1998-03-03 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE278651T1 publication Critical patent/ATE278651T1/de

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 title 1
238000006243 chemical reaction Methods 0.000 abstract 6
125000000217 alkyl group Chemical group 0.000 abstract 4
125000004509 1,3,4-oxadiazol-2-yl group Chemical group O1C(=NN=C1)* 0.000 abstract 3
KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 2
150000008064 anhydrides Chemical class 0.000 abstract 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
150000002148 esters Chemical class 0.000 abstract 2
125000005929 isobutyloxycarbonyl group Chemical group [H]C([H])([H])C([H])(C([H])([H])[H])C([H])([H])OC(*)=O 0.000 abstract 2
FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
PQCXFUXRTRESBD-UHFFFAOYSA-N (4-methoxycarbonylphenyl)boronic acid Chemical compound COC(=O)C1=CC=C(B(O)O)C=C1 PQCXFUXRTRESBD-UHFFFAOYSA-N 0.000 abstract 1
MEQBJJUWDCYIAB-UHFFFAOYSA-N 2-chloropyridin-3-amine Chemical compound NC1=CC=CN=C1Cl MEQBJJUWDCYIAB-UHFFFAOYSA-N 0.000 abstract 1
JRIUSNXEAMPSCD-UHFFFAOYSA-N 2-methylpropyl n-(3-methoxy-5-methylpyrazin-2-yl)carbamate Chemical compound COC1=NC(C)=CN=C1NC(=O)OCC(C)C JRIUSNXEAMPSCD-UHFFFAOYSA-N 0.000 abstract 1
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 1
PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 abstract 1
229910000102 alkali metal hydride Inorganic materials 0.000 abstract 1
150000008046 alkali metal hydrides Chemical class 0.000 abstract 1
239000002585 base Substances 0.000 abstract 1
ZADPBFCGQRWHPN-UHFFFAOYSA-N boronic acid Chemical compound OBO ZADPBFCGQRWHPN-UHFFFAOYSA-N 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
239000012954 diazonium Substances 0.000 abstract 1
150000001989 diazonium salts Chemical class 0.000 abstract 1
239000012442 inert solvent Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000004492 methyl ester group Chemical group 0.000 abstract 1
229910052763 palladium Inorganic materials 0.000 abstract 1
125000006239 protecting group Chemical group 0.000 abstract 1
230000027756 respiratory electron transport chain Effects 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pyridine Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Physical Or Chemical Processes And Apparatus (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Catalysts (AREA)

AT98908219T 1997-03-07 1998-03-03 Verfahren zur herstellung von arylsulfonylchlorid ATE278651T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GBGB9704762.5A GB9704762D0 (en)	1997-03-07	1997-03-07	Chemical process
PCT/GB1998/000651 WO1998040332A1 (en)	1997-03-07	1998-03-03	Process for the manufacture of arylsulfonyl chloride

Publications (1)

Publication Number	Publication Date
ATE278651T1 true ATE278651T1 (de)	2004-10-15

Family

ID=10808874

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT98908219T ATE278651T1 (de)	1997-03-07	1998-03-03	Verfahren zur herstellung von arylsulfonylchlorid

Country Status (12)

Country	Link
US (2)	US6531605B1 (de)
EP (1)	EP0973704B1 (de)
JP (1)	JP4046360B2 (de)
AT (1)	ATE278651T1 (de)
AU (1)	AU6630098A (de)
DE (1)	DE69826845T2 (de)
DK (1)	DK0973704T3 (de)
ES (1)	ES2227807T3 (de)
GB (1)	GB9704762D0 (de)
PT (1)	PT973704E (de)
WO (1)	WO1998040332A1 (de)
ZA (1)	ZA981933B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BR0213824A (pt) *	2001-11-06	2004-08-31	Wyeth Corp	Processo para a preparação de cloretos de 2-[alquil(aril)] sulfonilbenzenossulfonila e dos seus intermediários
GB0219660D0 (en)	2002-08-23	2002-10-02	Astrazeneca Ab	Therapeutic use
GB0403744D0 (en) *	2004-02-20	2004-03-24	Astrazeneca Ab	Chemical process
US7625895B2 (en) *	2007-04-12	2009-12-01	Hoffmann-Le Roche Inc.	Diphenyl-dihydro-imidazopyridinones
AU2009334570B2 (en)	2008-12-29	2016-06-09	Sanofi	Derivatives of 2-pyridin-2-yl-pyrazol-3(2h)-one, preparation and therapeutic use thereof
US20120309796A1 (en)	2011-06-06	2012-12-06	Fariborz Firooznia	Benzocycloheptene acetic acids
CN102491973A (zh) *	2011-12-15	2012-06-13	南京友杰医药科技有限公司	Zd-4054的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE859461C (de) *	1942-12-02	1952-12-15	Bayer Ag	Verfahren zur Darstellung von aromatischen Sulfonsaeurehalogeniden
CH590830A5 (de) *	1973-02-20	1977-08-31	Hoechst Ag
US4714700A (en) *	1982-04-20	1987-12-22	Choay S.A.	N-substituted 2,4-dialkoxy benzenesulfonamides and pharmaceutical compositions
UA58494C2 (uk) *	1995-06-07	2003-08-15	Зенека Лімітед	Похідні n-гетероарилпіридинсульфонаміду, фармацевтична композиція, спосіб одержання та спосіб протидії впливам ендотеліну

1997
- 1997-03-07 GB GBGB9704762.5A patent/GB9704762D0/en active Pending
1998
- 1998-03-03 ES ES98908219T patent/ES2227807T3/es not_active Expired - Lifetime
- 1998-03-03 US US09/380,478 patent/US6531605B1/en not_active Expired - Fee Related
- 1998-03-03 AT AT98908219T patent/ATE278651T1/de active
- 1998-03-03 AU AU66300/98A patent/AU6630098A/en not_active Abandoned
- 1998-03-03 DK DK98908219T patent/DK0973704T3/da active
- 1998-03-03 PT PT98908219T patent/PT973704E/pt unknown
- 1998-03-03 JP JP53933698A patent/JP4046360B2/ja not_active Expired - Fee Related
- 1998-03-03 EP EP98908219A patent/EP0973704B1/de not_active Expired - Lifetime
- 1998-03-03 DE DE69826845T patent/DE69826845T2/de not_active Expired - Lifetime
- 1998-03-03 WO PCT/GB1998/000651 patent/WO1998040332A1/en not_active Ceased
- 1998-03-06 ZA ZA981933A patent/ZA981933B/xx unknown
2003
- 2003-01-22 US US10/348,229 patent/US6943254B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
PT973704E (pt)	2005-01-31
ZA981933B (en)	1998-09-07
WO1998040332A1 (en)	1998-09-17
EP0973704A1 (de)	2000-01-26
US20030162973A1 (en)	2003-08-28
AU6630098A (en)	1998-09-29
DE69826845D1 (de)	2004-11-11
EP0973704B1 (de)	2004-10-06
GB9704762D0 (en)	1997-04-23
JP4046360B2 (ja)	2008-02-13
ES2227807T3 (es)	2005-04-01
US6531605B1 (en)	2003-03-11
DE69826845T2 (de)	2006-03-09
DK0973704T3 (da)	2005-01-17
JP2001514648A (ja)	2001-09-11
US6943254B2 (en)	2005-09-13

Legal Events

Date

Code

Title

Description

2005-05-15

UEP

Publication of translation of european patent specification

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