ATE279113T1 - Hypoxanthin- und thiohypxanthin-verbindungen - Google Patents

Hypoxanthin- und thiohypxanthin-verbindungen

Info

Publication number: ATE279113T1
Authority: AT; Austria
Prior art keywords: compounds; thiohypxanthine; hypoxanthine; inhibitors; formula
Prior art date: 1999-08-12

Application number

AT00953925T

Other languages

English (en)

Inventor

Mark Chasin

Peter Hofer

David Cavalla

Original Assignee

Euro Celtique Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-08-12

Filing date

2000-08-09

Publication date

2004-10-15

2000-08-09 Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE279113T1 publication Critical patent/ATE279113T1/de

Links

150000001875 compounds Chemical class 0.000 title abstract 3
FDGQSTZJBFJUBT-UHFFFAOYSA-N hypoxanthine Chemical compound O=C1NC=NC2=C1NC=N2 FDGQSTZJBFJUBT-UHFFFAOYSA-N 0.000 title 2
UGQMRVRMYYASKQ-UHFFFAOYSA-N Hypoxanthine nucleoside Natural products OC1C(O)C(CO)OC1N1C(NC=NC2=O)=C2N=C1 UGQMRVRMYYASKQ-UHFFFAOYSA-N 0.000 title 1
239000002587 phosphodiesterase IV inhibitor Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/36—Sulfur atom
- C07D473/38—Sulfur atom attached in position 6
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pulmonology (AREA)
Immunology (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

AT00953925T 1999-08-12 2000-08-09 Hypoxanthin- und thiohypxanthin-verbindungen ATE279113T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14862399P	1999-08-12	1999-08-12
PCT/US2000/021836 WO2001011967A1 (en)	1999-08-12	2000-08-09	Novel hypoxanthine and thiohypoxanthine compounds

Publications (1)

Publication Number	Publication Date
ATE279113T1 true ATE279113T1 (de)	2004-10-15

Family

ID=22526585

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00953925T ATE279113T1 (de)	1999-08-12	2000-08-09	Hypoxanthin- und thiohypxanthin-verbindungen

Country Status (7)

Country	Link
EP (1)	EP1202628B1 (de)
JP (1)	JP2003506467A (de)
AT (1)	ATE279113T1 (de)
AU (1)	AU6629000A (de)
CA (1)	CA2379356A1 (de)
DE (1)	DE60014915T2 (de)
WO (1)	WO2001011967A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2463067A1 (en) *	2001-10-26	2003-05-08	Sciclone Pharmaceuticals, Inc.	Pharmaceutical formulations comprising substituted xanthine compounds
AR039385A1 (es)	2002-04-19	2005-02-16	Astrazeneca Ab	Derivados de tioxantina como inhibidores de la mieloperoxidasa
CN114588161A (zh) *	2020-12-07	2022-06-07	四川大学华西医院	具有防治肺炎作用的次黄碱衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL24642A (en) *	1965-11-18	1971-06-23	Rashi M	Method for preparation of 6-thioxo purines from 6-methylthio purines
GB9312853D0 (en) *	1993-06-22	1993-08-04	Euro Celtique Sa	Chemical compounds
EP0814809B1 (de) *	1994-12-13	2003-08-13	Euroceltique S.A.	Arylthioxanthine
US5864037A (en) *	1996-06-06	1999-01-26	Euro-Celtique, S.A.	Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US6040447A (en) *	1997-12-12	2000-03-21	Euro-Celtique S.A.	Purine compounds having PDE IV inhibitory activity and methods of synthesis

2000
- 2000-08-09 WO PCT/US2000/021836 patent/WO2001011967A1/en not_active Ceased
- 2000-08-09 JP JP2001516330A patent/JP2003506467A/ja active Pending
- 2000-08-09 CA CA002379356A patent/CA2379356A1/en not_active Abandoned
- 2000-08-09 EP EP00953925A patent/EP1202628B1/de not_active Expired - Lifetime
- 2000-08-09 AT AT00953925T patent/ATE279113T1/de not_active IP Right Cessation
- 2000-08-09 AU AU66290/00A patent/AU6629000A/en not_active Abandoned
- 2000-08-09 DE DE60014915T patent/DE60014915T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE60014915T2 (de)	2005-10-13
WO2001011967A1 (en)	2001-02-22
AU6629000A (en)	2001-03-13
EP1202628A1 (de)	2002-05-08
EP1202628A4 (de)	2002-10-30
CA2379356A1 (en)	2001-02-22
JP2003506467A (ja)	2003-02-18
DE60014915D1 (de)	2004-11-18
EP1202628B1 (de)	2004-10-13

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Legal Events

Date	Code	Title	Description
2005-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties