ATE279395T1 - Carbostyrylderivate zur inhibition von hautrötungen und/oder von hautpigmentierung - Google Patents

Carbostyrylderivate zur inhibition von hautrötungen und/oder von hautpigmentierung

Info

Publication number
ATE279395T1
ATE279395T1 AT98937851T AT98937851T ATE279395T1 AT E279395 T1 ATE279395 T1 AT E279395T1 AT 98937851 T AT98937851 T AT 98937851T AT 98937851 T AT98937851 T AT 98937851T AT E279395 T1 ATE279395 T1 AT E279395T1
Authority
AT
Austria
Prior art keywords
skin
inhibiting
redness
pigmentation
carbostyryl derivatives
Prior art date
Application number
AT98937851T
Other languages
English (en)
Inventor
Yasuo Oshiro
Takao Nishi
Keiichi Kuwahara
Kozo Watanabe
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Application granted granted Critical
Publication of ATE279395T1 publication Critical patent/ATE279395T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
AT98937851T 1997-08-19 1998-08-18 Carbostyrylderivate zur inhibition von hautrötungen und/oder von hautpigmentierung ATE279395T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22243197 1997-08-19
PCT/JP1998/003657 WO1999009011A1 (en) 1997-08-19 1998-08-18 Carbostyril derivatives for inhibiting skin erythema and/or skin pigmentation

Publications (1)

Publication Number Publication Date
ATE279395T1 true ATE279395T1 (de) 2004-10-15

Family

ID=16782296

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98937851T ATE279395T1 (de) 1997-08-19 1998-08-18 Carbostyrylderivate zur inhibition von hautrötungen und/oder von hautpigmentierung

Country Status (19)

Country Link
US (1) US6133264A (de)
EP (1) EP1005458B1 (de)
JP (1) JPH11124366A (de)
KR (1) KR100397201B1 (de)
CN (1) CN1141298C (de)
AR (1) AR013945A1 (de)
AT (1) ATE279395T1 (de)
AU (1) AU725464B2 (de)
BR (1) BR9811307A (de)
CA (1) CA2297439C (de)
DE (1) DE69827014T2 (de)
DK (1) DK1005458T3 (de)
EG (1) EG24161A (de)
ES (1) ES2232001T3 (de)
ID (1) ID23521A (de)
MY (1) MY115907A (de)
PT (1) PT1005458E (de)
TW (1) TW436483B (de)
WO (1) WO1999009011A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020034772A1 (en) 1999-06-29 2002-03-21 Orlow Seth J. Methods and compositions that affect melanogenesis
US20020114769A1 (en) * 2000-09-14 2002-08-22 Rotenberg Susan A. Novel dequalinium analogs
WO2011094016A1 (en) 2010-01-28 2011-08-04 New York University Compounds, compositions and methods for preventing skin darkening
WO2012103487A1 (en) 2011-01-27 2012-08-02 New York University Coumarin compounds as melanogenesis modifiers and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1219587A (en) * 1981-12-14 1987-03-24 Norman P. Jensen Hydroxybenzylaminobenzenes as anti-inflammatory agents
US5082847A (en) * 1990-07-18 1992-01-21 Syntex (U.S.A.) Inc. Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility
US5576324A (en) * 1992-05-01 1996-11-19 Kowa Co., Ltd. Quinoline derivatives or salt thereof and remedy for cardiac diseases containing the same
TW448161B (en) * 1994-07-14 2001-08-01 Otsuka Pharma Co Ltd Cyclic amide derivatives
JP3042894B2 (ja) * 1995-07-07 2000-05-22 ファイザー製薬株式会社 サブスタンスｐアンタゴニストとしての置換ベンゾラクタム化合物
EP0918522A4 (de) * 1996-05-20 1999-08-18 Merck & Co Inc Antagonisten des gonadotropin-releasinghormons
WO1997044321A1 (en) * 1996-05-20 1997-11-27 Merck & Co., Inc. Antagonists of gonadotropin releasing hormone

Also Published As

Publication number Publication date
KR20010023086A (ko) 2001-03-26
CA2297439C (en) 2006-12-19
CA2297439A1 (en) 1999-02-25
CN1141298C (zh) 2004-03-10
AU725464B2 (en) 2000-10-12
BR9811307A (pt) 2000-08-29
TW436483B (en) 2001-05-28
AR013945A1 (es) 2001-01-31
JPH11124366A (ja) 1999-05-11
US6133264A (en) 2000-10-17
DK1005458T3 (da) 2005-01-31
MY115907A (en) 2003-09-30
DE69827014T2 (de) 2005-03-17
KR100397201B1 (ko) 2003-09-13
ID23521A (id) 2000-04-27
PT1005458E (pt) 2005-01-31
EG24161A (en) 2008-08-20
HK1029346A1 (en) 2001-03-30
EP1005458A1 (de) 2000-06-07
AU8650098A (en) 1999-03-08
ES2232001T3 (es) 2005-05-16
EP1005458B1 (de) 2004-10-13
DE69827014D1 (de) 2004-11-18
WO1999009011A1 (en) 1999-02-25
CN1267284A (zh) 2000-09-20

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