ATE279400T1 - 3-substituierte 5-aryl-4-isoxazolcarbonitrile mit antiviraler wirkung - Google Patents

3-substituierte 5-aryl-4-isoxazolcarbonitrile mit antiviraler wirkung

Info

Publication number
ATE279400T1
ATE279400T1 AT99924906T AT99924906T ATE279400T1 AT E279400 T1 ATE279400 T1 AT E279400T1 AT 99924906 T AT99924906 T AT 99924906T AT 99924906 T AT99924906 T AT 99924906T AT E279400 T1 ATE279400 T1 AT E279400T1
Authority
AT
Austria
Prior art keywords
aryl
substituted
carbonitriles
isoxazole
antiviral effect
Prior art date
Application number
AT99924906T
Other languages
English (en)
Inventor
Ernesto Geremia
Gianna Tempera
Angelo Castro
Adriana Garozzo
Francesco Guerrera
Rossella Maria Campagna
Original Assignee
Univ Catania
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Catania filed Critical Univ Catania
Application granted granted Critical
Publication of ATE279400T1 publication Critical patent/ATE279400T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT99924906T 1998-05-15 1999-05-07 3-substituierte 5-aryl-4-isoxazolcarbonitrile mit antiviraler wirkung ATE279400T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT98MI001072A IT1299263B1 (it) 1998-05-15 1998-05-15 5-aril-4-isossazolcarbonitrili 3 sostituiti ad attivita' antivirale
PCT/EP1999/003153 WO1999059984A1 (en) 1998-05-15 1999-05-07 3-substituted 5-aryl-4-isoxazolecarbonitriles having antiviral activity

Publications (1)

Publication Number Publication Date
ATE279400T1 true ATE279400T1 (de) 2004-10-15

Family

ID=11380033

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99924906T ATE279400T1 (de) 1998-05-15 1999-05-07 3-substituierte 5-aryl-4-isoxazolcarbonitrile mit antiviraler wirkung

Country Status (12)

Country Link
US (1) US6414004B1 (de)
EP (1) EP1077956B1 (de)
JP (1) JP2002515496A (de)
AT (1) ATE279400T1 (de)
AU (1) AU4140299A (de)
DE (1) DE69921118T2 (de)
DK (1) DK1077956T3 (de)
ES (1) ES2229711T3 (de)
IT (1) IT1299263B1 (de)
PT (1) PT1077956E (de)
SI (1) SI1077956T1 (de)
WO (1) WO1999059984A1 (de)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA846525B (en) * 1983-08-29 1985-04-24 Sterling Drug Inc (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof

Also Published As

Publication number Publication date
WO1999059984A1 (en) 1999-11-25
US6414004B1 (en) 2002-07-02
EP1077956B1 (de) 2004-10-13
DE69921118T2 (de) 2006-02-02
JP2002515496A (ja) 2002-05-28
SI1077956T1 (en) 2005-02-28
AU4140299A (en) 1999-12-06
PT1077956E (pt) 2005-01-31
DE69921118D1 (de) 2004-11-18
ITMI981072A1 (it) 1999-11-15
EP1077956A1 (de) 2001-02-28
IT1299263B1 (it) 2000-02-29
DK1077956T3 (da) 2005-01-31
ES2229711T3 (es) 2005-04-16

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