ATE279531T1 - Test zum nachweis der aktivität von phospho-n- acetylmuramyl-pentapeptid-translokase - Google Patents

Test zum nachweis der aktivität von phospho-n- acetylmuramyl-pentapeptid-translokase

Info

Publication number: ATE279531T1
Authority: AT; Austria
Prior art keywords: pentapeptide; source; phospho; activity; propionate
Prior art date: 1999-04-22

Application number

AT00925833T

Other languages

English (en)

Inventor

Kaveri Das

Janakiraman Ramachandran

Original Assignee

Astrazeneca Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-04-22

Filing date

2000-04-19

Publication date

2004-10-15

2000-04-19 Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE279531T1 publication Critical patent/ATE279531T1/de

Links

230000000694 effects Effects 0.000 title abstract 3
108700023478 Phospho-N-acetylmuramoyl-pentapeptide-transferases Proteins 0.000 title abstract 2
108090000790 Enzymes Proteins 0.000 abstract 2
102000004190 Enzymes Human genes 0.000 abstract 2
239000011541 reaction mixture Substances 0.000 abstract 2
AASBXERNXVFUEJ-UHFFFAOYSA-N (2,5-dioxopyrrolidin-1-yl) propanoate Chemical group CCC(=O)ON1C(=O)CCC1=O AASBXERNXVFUEJ-UHFFFAOYSA-N 0.000 abstract 1
XBDQKXXYIPTUBI-RVQWGROCSA-N 2,3-ditritiopropanoic acid Chemical group C(C(C[3H])[3H])(=O)O XBDQKXXYIPTUBI-RVQWGROCSA-N 0.000 abstract 1
239000012736 aqueous medium Substances 0.000 abstract 1
238000003556 assay Methods 0.000 abstract 1
239000003599 detergent Substances 0.000 abstract 1
UFPHFKCTOZIAFY-NTDVEAECSA-N ditrans,polycis-undecaprenyl phosphate Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/CC\C(C)=C/COP(O)(O)=O UFPHFKCTOZIAFY-NTDVEAECSA-N 0.000 abstract 1
238000006911 enzymatic reaction Methods 0.000 abstract 1
238000000605 extraction Methods 0.000 abstract 1
229910021645 metal ion Inorganic materials 0.000 abstract 1
230000020477 pH reduction Effects 0.000 abstract 1
150000003242 quaternary ammonium salts Chemical class 0.000 abstract 1
230000002285 radioactive effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Biophysics (AREA)
Analytical Chemistry (AREA)
Immunology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT00925833T 1999-04-22 2000-04-19 Test zum nachweis der aktivität von phospho-n- acetylmuramyl-pentapeptid-translokase ATE279531T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IN9900013		1999-04-22
PCT/SE2000/000772 WO2000065087A1 (en)	1999-04-22	2000-04-19	Assay for detecting phospho-n-acetylmuramyl-pentapeptide translocase activity

Publications (1)

Publication Number	Publication Date
ATE279531T1 true ATE279531T1 (de)	2004-10-15

Family

ID=11076654

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00925833T ATE279531T1 (de)	1999-04-22	2000-04-19	Test zum nachweis der aktivität von phospho-n- acetylmuramyl-pentapeptid-translokase

Country Status (9)

Country	Link
US (1)	US6537770B1 (de)
EP (1)	EP1171631B1 (de)
JP (1)	JP2002542792A (de)
CN (1)	CN1157484C (de)
AT (1)	ATE279531T1 (de)
AU (1)	AU769842B2 (de)
CA (1)	CA2370469A1 (de)
DE (1)	DE60014879T2 (de)
WO (1)	WO2000065087A1 (de)

Families Citing this family (28)

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US7157277B2 (en)	2001-11-28	2007-01-02	Neose Technologies, Inc.	Factor VIII remodeling and glycoconjugation of Factor VIII
US7439043B2 (en) *	2001-10-10	2008-10-21	Neose Technologies, Inc.	Galactosyl nucleotide sugars
US7173003B2 (en)	2001-10-10	2007-02-06	Neose Technologies, Inc.	Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en)	2001-10-10	2007-05-08	Neose Technologies, Inc.	Erythropoietin: remodeling and glycoconjugation of erythropoietin
US7473680B2 (en)	2001-11-28	2009-01-06	Neose Technologies, Inc.	Remodeling and glycoconjugation of peptides
SE0104102D0 (sv) *	2001-12-05	2001-12-05	Astrazeneca Ab	New assay
KR20060003862A (ko)	2003-03-14	2006-01-11	네오스 테크놀로지스, 인크.	수용성분기폴리머 및 그 접합체
WO2004091499A2 (en)	2003-04-09	2004-10-28	Neose Technologies, Inc.	Intracellular formation of peptide conjugates
US8791070B2 (en)	2003-04-09	2014-07-29	Novo Nordisk A/S	Glycopegylated factor IX
EP2055189A1 (de)	2003-04-09	2009-05-06	Neose Technologies, Inc.	Glycopegylierungsverfahren und durch die Verfahren hergestellte Proteine/Peptide
WO2005012484A2 (en)	2003-07-25	2005-02-10	Neose Technologies, Inc.	Antibody-toxin conjugates
ES2445948T3 (es)	2003-11-24	2014-03-06	Ratiopharm Gmbh	Eritropoyetina glicopegilada
US20080305992A1 (en)	2003-11-24	2008-12-11	Neose Technologies, Inc.	Glycopegylated erythropoietin
US20060040856A1 (en)	2003-12-03	2006-02-23	Neose Technologies, Inc.	Glycopegylated factor IX
US7338933B2 (en)	2004-01-08	2008-03-04	Neose Technologies, Inc.	O-linked glycosylation of peptides
WO2006010143A2 (en)	2004-07-13	2006-01-26	Neose Technologies, Inc.	Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
WO2006031811A2 (en)	2004-09-10	2006-03-23	Neose Technologies, Inc.	Glycopegylated interferon alpha
US20080176790A1 (en)	2004-10-29	2008-07-24	Defrees Shawn	Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf)
US9029331B2 (en)	2005-01-10	2015-05-12	Novo Nordisk A/S	Glycopegylated granulocyte colony stimulating factor
US20070154992A1 (en)	2005-04-08	2007-07-05	Neose Technologies, Inc.	Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
EP1891231A4 (de)	2005-05-25	2011-06-22	Novo Nordisk As	Glykopegylierter faktor ix
US20070105755A1 (en)	2005-10-26	2007-05-10	Neose Technologies, Inc.	One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en)	2005-11-03	2007-05-18	Neose Technologies, Inc.	Nucleotide sugar purification using membranes
ES2516694T3 (es)	2006-07-21	2014-10-31	Ratiopharm Gmbh	Glicosilación de péptidos a través de secuencias de glicosilación con unión en O
US8969532B2 (en)	2006-10-03	2015-03-03	Novo Nordisk A/S	Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
KR20100016160A (ko)	2007-04-03	2010-02-12	바이오제너릭스 에이지	글리코페길화 ｇ―ｃｓｆ를 이용하는 치료 방법
WO2008154639A2 (en)	2007-06-12	2008-12-18	Neose Technologies, Inc.	Improved process for the production of nucleotide sugars
KR101582841B1 (ko)	2008-02-27	2016-01-11	노보 노르디스크 에이/에스	콘쥬게이트된 인자 ｖｉｉｉ 분자

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5861318A (en)	1994-11-16	1999-01-19	Pharmacia & Upjohn Company	Scintillation proximity assay for N-acetylgalactosaminyltransferase activity
EP0890644A3 (de)	1997-07-10	1999-09-29	Smithkline Beecham Corporation	MurA Gen vom Staphylococcus aureus das für DP-N-Acetylglucosamine enolpyruvyl transferase kodiert
US6156537A (en)	1997-08-12	2000-12-05	Smithkline Beecham Corporation	Phospho-N-acetylmuramoyl-pentapeptide transferase of Streptococcus pneumoniae
EP1105148A4 (de)	1998-08-20	2003-02-05	Incara Pharmaceuticals Corp	Analoga von udp-murnac peptiden, testverfahren und kits
WO2001094623A1 (en) *	2000-06-08	2001-12-13	Astrazeneca Ab	Assay for detection of translocase enzyme activity in drug screening

2000
- 2000-04-19 AU AU44461/00A patent/AU769842B2/en not_active Ceased
- 2000-04-19 DE DE60014879T patent/DE60014879T2/de not_active Expired - Fee Related
- 2000-04-19 EP EP00925833A patent/EP1171631B1/de not_active Expired - Lifetime
- 2000-04-19 CN CNB00806590XA patent/CN1157484C/zh not_active Expired - Fee Related
- 2000-04-19 US US09/582,466 patent/US6537770B1/en not_active Expired - Fee Related
- 2000-04-19 WO PCT/SE2000/000772 patent/WO2000065087A1/en not_active Ceased
- 2000-04-19 AT AT00925833T patent/ATE279531T1/de not_active IP Right Cessation
- 2000-04-19 JP JP2000614421A patent/JP2002542792A/ja not_active Ceased
- 2000-04-19 CA CA002370469A patent/CA2370469A1/en not_active Abandoned

Also Published As

Publication number	Publication date
HK1044027A1 (en)	2002-10-04
JP2002542792A (ja)	2002-12-17
CA2370469A1 (en)	2000-11-02
DE60014879D1 (de)	2004-11-18
AU4446100A (en)	2000-11-10
EP1171631A1 (de)	2002-01-16
CN1157484C (zh)	2004-07-14
CN1348503A (zh)	2002-05-08
WO2000065087A1 (en)	2000-11-02
AU769842B2 (en)	2004-02-05
EP1171631B1 (de)	2004-10-13
US6537770B1 (en)	2003-03-25
DE60014879T2 (de)	2005-10-13

Legal Events

Date	Code	Title	Description
2005-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE279531T1 (de)	2004-10-15	Test zum nachweis der aktivität von phospho-n- acetylmuramyl-pentapeptid-translokase
ATE489633T1 (de)	2010-12-15	Verfahren zum frühzeitigen nachweis herzerkrankungen
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WO1998046993A3 (en)	1999-01-21	Method for diagnosing cancer by measuring the presence of creatine kinase inhibitor
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EP1204737A4 (de)	2004-04-14	Interne qualitätskontrolle
TR200501513T3 (tr)	2005-06-21	Tesadüfi ajanların saptanmasında ribozimlerin kullanılması.
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